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The map label for this gene is aatA [H]

Identifier: 162148896

GI number: 162148896

Start: 3216687

End: 3217889

Strand: Reverse

Name: aatA [H]

Synonym: GDI_3126

Alternate gene names: 162148896

Gene position: 3217889-3216687 (Counterclockwise)

Preceding gene: 162148897

Following gene: 162148895

Centisome position: 81.59

GC content: 67.33

Gene sequence:

>1203_bases
ATGGATCTTATCGCCGCCCGTCTAAACAAGGTCAGCCCCAGCCAGACCATCGCCATCTCCACCAAGGCGCGCGCCTTGAA
GGAAGCCGGACAGGACGTCATCAGCCTGTCGGCCGGCGAGCCCGATTTCGACACCCCCCGGAACATCAAGGACGCGGCGA
TCCGCGCCATCGAAGCGGGCCAGACGAAATATACCGACGTCGCCGGCACGCTGCCGCTGCGCCGGGCCGTGGCCGAGCGG
TTCCGCATCGATTCCGGCCTGGATTACACACCGGACGAGATCATCGTTTCCACCGGCGGCAAGCAGGTGATCTACAACGC
CATGGTCGCGACGCTGAATGCGGGGGACGAGGCGATCATCCCCGCGCCGTGCTGGGTGTCCTATCCCGATATCGTGGCGC
TGGCCGATGGCGTGCCCGTCATCGTCCCGTGCGCGGCGGAGACCGGGTTCAAGCTGCGGGCGGCCGACCTGGAGGCCGCC
ATCACGCCCCGGACCAAGTGGTTCTTCCTGAACTCGCCCTGCAACCCGACCGGCGCCGCCTATTCGGCCGAGGACCTGCG
GCCGATCTGCGACGTGCTGCTGCGGCACCCGGATGTCTGGATCTTCACCGACGATATCTATGACAAGCTGGTCTATGATG
GGTTCACGCCCGCCACCATCGTGCAGGTCGAACCCCGGCTGCGCGACCGGACGGTGACGATGAACGGTGTGTCCAAGGCC
TATGCCATGACCGGCTGGCGCATCGGCTTTTCCGGCGCGCCGGCCGTGCTGACGCGCGCGATGAACAAGCTGCAGAGCCA
GTCGACCTCGGGCACCTGCTCGATCAGCCAGGCGGCGGCGCTGGAGGCCCTGTCCGGCCCGCAGGACTTCATCGGCGACA
TGGTGCGCGCCTACCAGGACCGCCGCGACCTGGTGGTGGGCATGATGAACCAGGCGCGCGGCCTGACCTGTTCCCGGCCC
GAGGGCGCGTTCTACGTCTTCCCGTCGATCGAGGGATGCCTGGGCAAGGTCAGCGCCGGCGGGACGGCCATCGTCGATGA
CGAGGCCTTCGTCACCGCCCTGCTGGAGGAAGAGGGCGTGGCGGCGGTGCATGGCGCGGCCTTCATGTTCGCCGGCCATT
TCCGCATTTCCTACGCGACCGATACCGAAAGCCTGCGCGAAGCCTGCACCCGCATCCAGCGCTTCTGCGCCGGGTTGCGC
TGA

Upstream 100 bases:

>100_bases
GGATCAGCGGTTTACCTCGCGCTGCGCTTCGCATTACGGTGGCTTCCGCGTCGGGCCCGACAGGGGCGCGCGTTTCCCGT
TCCTCTGGATCTTCGGTGTC

Downstream 100 bases:

>100_bases
ACGTGACGGGCACGGGTCCGGCGGGCGTCGGGGTGGCCGAACCGGGCTTTGCCGCGCGCACCGCGCGCCTGGACTCGCCC
GCCACCATCGCCATGGCGGT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MDLIAARLNKVSPSQTIAISTKARALKEAGQDVISLSAGEPDFDTPRNIKDAAIRAIEAGQTKYTDVAGTLPLRRAVAER
FRIDSGLDYTPDEIIVSTGGKQVIYNAMVATLNAGDEAIIPAPCWVSYPDIVALADGVPVIVPCAAETGFKLRAADLEAA
ITPRTKWFFLNSPCNPTGAAYSAEDLRPICDVLLRHPDVWIFTDDIYDKLVYDGFTPATIVQVEPRLRDRTVTMNGVSKA
YAMTGWRIGFSGAPAVLTRAMNKLQSQSTSGTCSISQAAALEALSGPQDFIGDMVRAYQDRRDLVVGMMNQARGLTCSRP
EGAFYVFPSIEGCLGKVSAGGTAIVDDEAFVTALLEEEGVAAVHGAAFMFAGHFRISYATDTESLREACTRIQRFCAGLR

Sequences:

>Translated_400_residues
MDLIAARLNKVSPSQTIAISTKARALKEAGQDVISLSAGEPDFDTPRNIKDAAIRAIEAGQTKYTDVAGTLPLRRAVAER
FRIDSGLDYTPDEIIVSTGGKQVIYNAMVATLNAGDEAIIPAPCWVSYPDIVALADGVPVIVPCAAETGFKLRAADLEAA
ITPRTKWFFLNSPCNPTGAAYSAEDLRPICDVLLRHPDVWIFTDDIYDKLVYDGFTPATIVQVEPRLRDRTVTMNGVSKA
YAMTGWRIGFSGAPAVLTRAMNKLQSQSTSGTCSISQAAALEALSGPQDFIGDMVRAYQDRRDLVVGMMNQARGLTCSRP
EGAFYVFPSIEGCLGKVSAGGTAIVDDEAFVTALLEEEGVAAVHGAAFMFAGHFRISYATDTESLREACTRIQRFCAGLR
>Mature_400_residues
MDLIAARLNKVSPSQTIAISTKARALKEAGQDVISLSAGEPDFDTPRNIKDAAIRAIEAGQTKYTDVAGTLPLRRAVAER
FRIDSGLDYTPDEIIVSTGGKQVIYNAMVATLNAGDEAIIPAPCWVSYPDIVALADGVPVIVPCAAETGFKLRAADLEAA
ITPRTKWFFLNSPCNPTGAAYSAEDLRPICDVLLRHPDVWIFTDDIYDKLVYDGFTPATIVQVEPRLRDRTVTMNGVSKA
YAMTGWRIGFSGAPAVLTRAMNKLQSQSTSGTCSISQAAALEALSGPQDFIGDMVRAYQDRRDLVVGMMNQARGLTCSRP
EGAFYVFPSIEGCLGKVSAGGTAIVDDEAFVTALLEEEGVAAVHGAAFMFAGHFRISYATDTESLREACTRIQRFCAGLR

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=26.1306532663317, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=26.1306532663317, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI56713254, Length=365, Percent_Identity=25.7534246575342, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI56713256, Length=365, Percent_Identity=25.7534246575342, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI4507369, Length=394, Percent_Identity=24.1116751269036, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI169881281, Length=308, Percent_Identity=25, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1788627, Length=393, Percent_Identity=31.8066157760814, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1786816, Length=392, Percent_Identity=26.7857142857143, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788722, Length=400, Percent_Identity=29.75, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1790797, Length=313, Percent_Identity=27.1565495207668, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=401, Percent_Identity=26.1845386533666, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71994472, Length=376, Percent_Identity=25, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994476, Length=376, Percent_Identity=25, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=318, Percent_Identity=26.1006289308176, Blast_Score=101, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6322401, Length=401, Percent_Identity=23.1920199501247, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28573069, Length=390, Percent_Identity=24.8717948717949, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24646114, Length=390, Percent_Identity=24.8717948717949, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28573067, Length=390, Percent_Identity=24.8717948717949, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28573065, Length=390, Percent_Identity=24.8717948717949, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI18859735, Length=410, Percent_Identity=23.6585365853659, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43021; Mature: 43021

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLIAARLNKVSPSQTIAISTKARALKEAGQDVISLSAGEPDFDTPRNIKDAAIRAIEAG
CCCHHHHHCCCCCCCEEEEEHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCC
QTKYTDVAGTLPLRRAVAERFRIDSGLDYTPDEIIVSTGGKQVIYNAMVATLNAGDEAII
CCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHEECCCCCEEE
PAPCWVSYPDIVALADGVPVIVPCAAETGFKLRAADLEAAITPRTKWFFLNSPCNPTGAA
CCCCCCCCCCCEEECCCCCEEEECCCCCCCEEEECCCCEEECCCEEEEEECCCCCCCCCC
YSAEDLRPICDVLLRHPDVWIFTDDIYDKLVYDGFTPATIVQVEPRLRDRTVTMNGVSKA
CCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHH
YAMTGWRIGFSGAPAVLTRAMNKLQSQSTSGTCSISQAAALEALSGPQDFIGDMVRAYQD
HHEECEEECCCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHH
RRDLVVGMMNQARGLTCSRPEGAFYVFPSIEGCLGKVSAGGTAIVDDEAFVTALLEEEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHCCCCCCEEEECCHHHHHHHHHCCCC
AAVHGAAFMFAGHFRISYATDTESLREACTRIQRFCAGLR
EEEECCEEEEEEEEEEEEECCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLIAARLNKVSPSQTIAISTKARALKEAGQDVISLSAGEPDFDTPRNIKDAAIRAIEAG
CCCHHHHHCCCCCCCEEEEEHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCC
QTKYTDVAGTLPLRRAVAERFRIDSGLDYTPDEIIVSTGGKQVIYNAMVATLNAGDEAII
CCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHEECCCCCEEE
PAPCWVSYPDIVALADGVPVIVPCAAETGFKLRAADLEAAITPRTKWFFLNSPCNPTGAA
CCCCCCCCCCCEEECCCCCEEEECCCCCCCEEEECCCCEEECCCEEEEEECCCCCCCCCC
YSAEDLRPICDVLLRHPDVWIFTDDIYDKLVYDGFTPATIVQVEPRLRDRTVTMNGVSKA
CCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHH
YAMTGWRIGFSGAPAVLTRAMNKLQSQSTSGTCSISQAAALEALSGPQDFIGDMVRAYQD
HHEECEEECCCCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHH
RRDLVVGMMNQARGLTCSRPEGAFYVFPSIEGCLGKVSAGGTAIVDDEAFVTALLEEEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHCCCCCCEEEECCHHHHHHHHHCCCC
AAVHGAAFMFAGHFRISYATDTESLREACTRIQRFCAGLR
EEEECCEEEEEEEEEEEEECCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]