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The map label for this gene is thrB

Identifier: 162148871

GI number: 162148871

Start: 3194323

End: 3195288

Strand: Reverse

Name: thrB

Synonym: GDI_3101

Alternate gene names: 162148871

Gene position: 3195288-3194323 (Counterclockwise)

Preceding gene: 162148872

Following gene: 162148870

Centisome position: 81.01

GC content: 71.22

Gene sequence:

>966_bases
GTGGCGGTCTACACGGATGTGTCGGACGGGGCGCTGCGCGCGTTCCTGTCCCTGTACGATATCGGCGACCTGACGGCCTA
TCGCGGCATTGCCGAGGGCGTCGAGAACAGCAATTTCGTCCTGCGGACCACCGGCGGCGATTTCATCCTCACCTTGTACG
AACGGCGGGTGGACCCGGCCGACCTGCCCTGGTTCCTGGGGCTGATGGGCTGCCTGTCCGACCACGGCCTGTCCTGCCCG
CGTCCCGTCGTGGCGCGGGACGGGCAGGCGCTGCGCACGCTGGCCGGCCGCCCGGCGGCGATTACGACCTTCCTGCCCGG
CGTGTGGCCGCGCGAGGTGCGGGTGGCGCATTGCGCCCCGGTGGGCGCCGCCCTGGCAGCGCTGCACATGGCGGGGCAGG
GATTCGGGGCCGAGCGCGCCAACGCGCTGGGGCCGGATGCCTGGCCCGGCCTGGTCGCGGCATGCCGGGCCGATGGCGAT
TCGGTCCAGCCCGGCCTGATGGCGGAACTGGACGCGGCCCTGGCCGAGATCCTGCCCGCCTGGCCCGCCCGCGACGACCT
GCCGCGCGGGCAGATCCATGCCGACCTGTTCCCGGACAACGTGTTCTTCCTGGACGGCGCGGTGTCGGGAATCATCGACT
TCTACTTCGCCTGCACCGACCTGCTGGCCTACGACATCGCGATCTGCCTCAATGCCTGGTGTTTCGATGCGGACGGAACG
TTCGACGCCGCCCGGGGGCGGGCGCTGATCGCGGGGTACGAATCCGTGCGGCCCCTGACCGATGCCGAACGGCGGGCCCT
GCCGGTCCTGGCAGCCGGCGCCGCGACCCGTTTCCTGCTGACCCGGCTGTATGACTGGGTGAACACCCCGGCGGGGGCCA
TGGTCACGCGCAAGGACCCGCTGGATTACCTGAAGCGCCTGCGGTTCCACCGCGCGGCACGGAACATGGCGTCCTATGGC
CTCTGA

Upstream 100 bases:

>100_bases
GGCCAAGCGCTTCACCCTGGAAATCGAGGAACGGACGGTCAAGGAAGAGAACGTGACCTTCCGCCTGCCGGCCCCGCTGG
GCTAGGCCGGGCCCTTCCAC

Downstream 100 bases:

>100_bases
CCCCCACCACCCGCCCGAGGCGGATGCCGAAACCGACCTCGCCCTGGTCGAGATCTGGACCGATGGCGGCTGCAAGCCCA
ATCCCGGCCCCGGCGGCTGG

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MAVYTDVSDGALRAFLSLYDIGDLTAYRGIAEGVENSNFVLRTTGGDFILTLYERRVDPADLPWFLGLMGCLSDHGLSCP
RPVVARDGQALRTLAGRPAAITTFLPGVWPREVRVAHCAPVGAALAALHMAGQGFGAERANALGPDAWPGLVAACRADGD
SVQPGLMAELDAALAEILPAWPARDDLPRGQIHADLFPDNVFFLDGAVSGIIDFYFACTDLLAYDIAICLNAWCFDADGT
FDAARGRALIAGYESVRPLTDAERRALPVLAAGAATRFLLTRLYDWVNTPAGAMVTRKDPLDYLKRLRFHRAARNMASYG
L

Sequences:

>Translated_321_residues
MAVYTDVSDGALRAFLSLYDIGDLTAYRGIAEGVENSNFVLRTTGGDFILTLYERRVDPADLPWFLGLMGCLSDHGLSCP
RPVVARDGQALRTLAGRPAAITTFLPGVWPREVRVAHCAPVGAALAALHMAGQGFGAERANALGPDAWPGLVAACRADGD
SVQPGLMAELDAALAEILPAWPARDDLPRGQIHADLFPDNVFFLDGAVSGIIDFYFACTDLLAYDIAICLNAWCFDADGT
FDAARGRALIAGYESVRPLTDAERRALPVLAAGAATRFLLTRLYDWVNTPAGAMVTRKDPLDYLKRLRFHRAARNMASYG
L
>Mature_320_residues
AVYTDVSDGALRAFLSLYDIGDLTAYRGIAEGVENSNFVLRTTGGDFILTLYERRVDPADLPWFLGLMGCLSDHGLSCPR
PVVARDGQALRTLAGRPAAITTFLPGVWPREVRVAHCAPVGAALAALHMAGQGFGAERANALGPDAWPGLVAACRADGDS
VQPGLMAELDAALAEILPAWPARDDLPRGQIHADLFPDNVFFLDGAVSGIIDFYFACTDLLAYDIAICLNAWCFDADGTF
DAARGRALIAGYESVRPLTDAERRALPVLAAGAATRFLLTRLYDWVNTPAGAMVTRKDPLDYLKRLRFHRAARNMASYGL

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KHSE_GLUDA (A9HS91)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001603332.1
- RefSeq:   YP_002277608.1
- ProteinModelPortal:   A9HS91
- SMR:   A9HS91
- GeneID:   5791930
- GeneID:   6976705
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_3266
- HOGENOM:   HBG309377
- OMA:   ADLFRDN
- ProtClustDB:   PRK05231
- HAMAP:   MF_00301
- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009
- TIGRFAMs:   TIGR00938

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.39

Molecular weight: Translated: 34561; Mature: 34430

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYTDVSDGALRAFLSLYDIGDLTAYRGIAEGVENSNFVLRTTGGDFILTLYERRVDPA
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEHHHHCCCCC
DLPWFLGLMGCLSDHGLSCPRPVVARDGQALRTLAGRPAAITTFLPGVWPREVRVAHCAP
CCHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHCH
VGAALAALHMAGQGFGAERANALGPDAWPGLVAACRADGDSVQPGLMAELDAALAEILPA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
WPARDDLPRGQIHADLFPDNVFFLDGAVSGIIDFYFACTDLLAYDIAICLNAWCFDADGT
CCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
FDAARGRALIAGYESVRPLTDAERRALPVLAAGAATRFLLTRLYDWVNTPAGAMVTRKDP
CHHHCCCEEEECHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCH
LDYLKRLRFHRAARNMASYGL
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVYTDVSDGALRAFLSLYDIGDLTAYRGIAEGVENSNFVLRTTGGDFILTLYERRVDPA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEHHHHCCCCC
DLPWFLGLMGCLSDHGLSCPRPVVARDGQALRTLAGRPAAITTFLPGVWPREVRVAHCAP
CCHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHCH
VGAALAALHMAGQGFGAERANALGPDAWPGLVAACRADGDSVQPGLMAELDAALAEILPA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
WPARDDLPRGQIHADLFPDNVFFLDGAVSGIIDFYFACTDLLAYDIAICLNAWCFDADGT
CCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
FDAARGRALIAGYESVRPLTDAERRALPVLAAGAATRFLLTRLYDWVNTPAGAMVTRKDP
CHHHCCCEEEECHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCH
LDYLKRLRFHRAARNMASYGL
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA