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The map label for this gene is ptrB [H]

Identifier: 162148842

GI number: 162148842

Start: 3168009

End: 3170096

Strand: Direct

Name: ptrB [H]

Synonym: GDI_3071

Alternate gene names: 162148842

Gene position: 3168009-3170096 (Clockwise)

Preceding gene: 162148841

Following gene: 162148843

Centisome position: 80.32

GC content: 68.01

Gene sequence:

>2088_bases
ATGACCACCCCCCCGGTCGCCCGCACGGACCCCCAGACGATCACGCAGCTCGGCCGGGTCCGCATCGACGAATATGGGTG
GATGAAGGACGAGAACTGGCAGGCCGTCCTGCGCGACCCATCGGTGCTGCGCGCGGACATCGCGGCGCACCTGCGGGCCG
AGAACGCCTACACCGCCGCCATCCTGGCCCCGACCGAATCCCTGCAGGCCACCATCGCCGCCGAGATGAAGGCCCGCATC
CGCGAGGATGATACCTATCCCGCGCTGCCGCACGGTCCCTGGCGCTATTACATGCGCTACGCGGCCGGCGCCCAGCACCC
GATCCATGCCCGCCACCCCGAGGGCCGGCCCGAGGCCGAGACGATCCTGCTGGACGTGGACCGGATGGCGAAGGGGCACG
AGTATTTCGCCGTCGCCACAGCGACCCACAGCCCCGACCACCTGCTGTTCGCCCATGCCGAGGACAATCAGGGGTCCGAG
GTCTATCGCGTCGTCATCAGCGACATCGCGCGCGGCACGCCGGTCGGGCCGGCGATCGAAAACTGCAGCGGCAATTTCGC
GTTTTCGCCCGACGCGCGGCATCTGTTCTGGACCTGGCGGGACGCGCATGGCCGCCCGACGAAGATCTTTCGCCGCCGCA
TCGGCACCGACGAGGACGTGCTGGTCTACGAGGAAACGGACCCCGGCTTCTTCATCGGGGTCGAGGCCAGCCGCTCCGGA
CGCTGGATCGTCATTTCGGCCAGCAACCAGGACACGTCCGAATCCTGGCTGATCCCCGGCGGCAATCCCGAGGCGGCGGC
CGCGTGCGTCGAGCCGCGCCGCACCGGCGTGCTCTACAGCCTTAGCCACTGGGGGGACCGCTTCGCGATCCTGACCAACA
CCGACGGCGCCGTCGATTTCAAGCTGATGGAAGCGCCCGATACCACCCCGGGGCGGGCGCACTGGCGCGACCTGGTCCCG
CACCTGCCCGGCCGCTACATCACCGACTGCATGGCCTTTTCCGGGCATCTGGTCTGGCGCGAGCGCCGGGATGCCAACAC
CGCGCTGGTCGTCCGCCGCGTCGACGGGACCGAGCATGTCCTGTCATCGGACGAGGACGCCTATGTCCTGTCCTTCTCGG
GGTCCTTCGAATACGACACGCGCGAATTGCGCTATGTCTACCAGTCGCCGACCACGCCCCGGCAATGGTACGCCTATGAC
ATGGACAGCCGTACCCGCCACCTGCTGAAGACGCAGGAGGTACCGTCGGGACACGACCCGCGCGATTACAGATGCTGGCG
CCTGACCGCCACCGCACTGGACGGGACGCAGGTGCCGATCACCGTGCTGGGGCTGCACGGCACGCCCATCGACGGCTCCG
CCCCCCTGCTGCTCTATGGTTACGGCTCGTACGGCCATGCGATCGAACCGACCTTTTCCACTGGGGTCTTCAGCCTGGTG
GACCGGGGATGGTTCTACGCCATCGCCCATGTGCGCGGCGGGTCGGAAAAGGGCTGGAACTGGTTCCTGGGCGGACGGGG
CCGCAACAAGCCCAACAGCTTCACCGATTTCATCGCCTGCGCCGAACACCTGATCGCGGACGGCTTCACCGGGGCGGGAC
GGATCGTGACGGACGGGCGTTCCGCCGGCGGGATGGTCATGGGGGCGATCGCCAACATGCGCCCCGACCTGTTCGCGGGA
ATCGTCGCCGTGGTGCCGTTCGTGGACGAGCTGAACACGATGTCGGACACCAGTCTGCCGCTGACGCCGCCGGAATGGCC
GGAATGGGGCAATCCGCTGGAAGATGAAGCGGCCTACGACCTGATCGCCAGCTATGCCGCCTATGAACAGGTGGCGCCGC
GCCCGTATCCGGCGATCCTGGCCATCGGCGGCCTGTCGGACCCGCGCGTGACCTACTGGGAACCGGCGAAATGGATCGCC
CGGCTGCGCGCGCACACGACGTCGTCCCGCCCGCTGCTGCTGCGCATCAACATGGAGGCCGGGCATGGCGGCGCGTCCGG
CCGCTTCGACGCATTGAAGGAGGCCGCCCTGATCCAGGCCTTCGCCATCTGGGCGGTGGATACGACCGACCATACGAGAA
CCGAATGA

Upstream 100 bases:

>100_bases
CCAGACGTTCTGAGCGTCTGTCGCACCCGCGAGCGGTCGGGTATGGTCTTGAGCCAATACCGGCCCCGCCCCCGGCGGAC
AGCGATGGAGAGGATGCACG

Downstream 100 bases:

>100_bases
GCGAGACGGACATGAAACAGGCATCCGCCCAACGAGGAACAGCATGACGGATCAGCCCCCCTCGCCCCTTCTGCCGCCTC
CCGACCGCTCCCCCTTCCGC

Product: protease II

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MTTPPVARTDPQTITQLGRVRIDEYGWMKDENWQAVLRDPSVLRADIAAHLRAENAYTAAILAPTESLQATIAAEMKARI
REDDTYPALPHGPWRYYMRYAAGAQHPIHARHPEGRPEAETILLDVDRMAKGHEYFAVATATHSPDHLLFAHAEDNQGSE
VYRVVISDIARGTPVGPAIENCSGNFAFSPDARHLFWTWRDAHGRPTKIFRRRIGTDEDVLVYEETDPGFFIGVEASRSG
RWIVISASNQDTSESWLIPGGNPEAAAACVEPRRTGVLYSLSHWGDRFAILTNTDGAVDFKLMEAPDTTPGRAHWRDLVP
HLPGRYITDCMAFSGHLVWRERRDANTALVVRRVDGTEHVLSSDEDAYVLSFSGSFEYDTRELRYVYQSPTTPRQWYAYD
MDSRTRHLLKTQEVPSGHDPRDYRCWRLTATALDGTQVPITVLGLHGTPIDGSAPLLLYGYGSYGHAIEPTFSTGVFSLV
DRGWFYAIAHVRGGSEKGWNWFLGGRGRNKPNSFTDFIACAEHLIADGFTGAGRIVTDGRSAGGMVMGAIANMRPDLFAG
IVAVVPFVDELNTMSDTSLPLTPPEWPEWGNPLEDEAAYDLIASYAAYEQVAPRPYPAILAIGGLSDPRVTYWEPAKWIA
RLRAHTTSSRPLLLRINMEAGHGGASGRFDALKEAALIQAFAIWAVDTTDHTRTE

Sequences:

>Translated_695_residues
MTTPPVARTDPQTITQLGRVRIDEYGWMKDENWQAVLRDPSVLRADIAAHLRAENAYTAAILAPTESLQATIAAEMKARI
REDDTYPALPHGPWRYYMRYAAGAQHPIHARHPEGRPEAETILLDVDRMAKGHEYFAVATATHSPDHLLFAHAEDNQGSE
VYRVVISDIARGTPVGPAIENCSGNFAFSPDARHLFWTWRDAHGRPTKIFRRRIGTDEDVLVYEETDPGFFIGVEASRSG
RWIVISASNQDTSESWLIPGGNPEAAAACVEPRRTGVLYSLSHWGDRFAILTNTDGAVDFKLMEAPDTTPGRAHWRDLVP
HLPGRYITDCMAFSGHLVWRERRDANTALVVRRVDGTEHVLSSDEDAYVLSFSGSFEYDTRELRYVYQSPTTPRQWYAYD
MDSRTRHLLKTQEVPSGHDPRDYRCWRLTATALDGTQVPITVLGLHGTPIDGSAPLLLYGYGSYGHAIEPTFSTGVFSLV
DRGWFYAIAHVRGGSEKGWNWFLGGRGRNKPNSFTDFIACAEHLIADGFTGAGRIVTDGRSAGGMVMGAIANMRPDLFAG
IVAVVPFVDELNTMSDTSLPLTPPEWPEWGNPLEDEAAYDLIASYAAYEQVAPRPYPAILAIGGLSDPRVTYWEPAKWIA
RLRAHTTSSRPLLLRINMEAGHGGASGRFDALKEAALIQAFAIWAVDTTDHTRTE
>Mature_694_residues
TTPPVARTDPQTITQLGRVRIDEYGWMKDENWQAVLRDPSVLRADIAAHLRAENAYTAAILAPTESLQATIAAEMKARIR
EDDTYPALPHGPWRYYMRYAAGAQHPIHARHPEGRPEAETILLDVDRMAKGHEYFAVATATHSPDHLLFAHAEDNQGSEV
YRVVISDIARGTPVGPAIENCSGNFAFSPDARHLFWTWRDAHGRPTKIFRRRIGTDEDVLVYEETDPGFFIGVEASRSGR
WIVISASNQDTSESWLIPGGNPEAAAACVEPRRTGVLYSLSHWGDRFAILTNTDGAVDFKLMEAPDTTPGRAHWRDLVPH
LPGRYITDCMAFSGHLVWRERRDANTALVVRRVDGTEHVLSSDEDAYVLSFSGSFEYDTRELRYVYQSPTTPRQWYAYDM
DSRTRHLLKTQEVPSGHDPRDYRCWRLTATALDGTQVPITVLGLHGTPIDGSAPLLLYGYGSYGHAIEPTFSTGVFSLVD
RGWFYAIAHVRGGSEKGWNWFLGGRGRNKPNSFTDFIACAEHLIADGFTGAGRIVTDGRSAGGMVMGAIANMRPDLFAGI
VAVVPFVDELNTMSDTSLPLTPPEWPEWGNPLEDEAAYDLIASYAAYEQVAPRPYPAILAIGGLSDPRVTYWEPAKWIAR
LRAHTTSSRPLLLRINMEAGHGGASGRFDALKEAALIQAFAIWAVDTTDHTRTE

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172420, Length=529, Percent_Identity=30.0567107750473, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI284172413, Length=529, Percent_Identity=30.0567107750473, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI70778815, Length=529, Percent_Identity=30.0567107750473, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI284172438, Length=563, Percent_Identity=28.4191829484902, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI284172431, Length=563, Percent_Identity=28.4191829484902, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI41349456, Length=723, Percent_Identity=24.4813278008299, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI108860686, Length=527, Percent_Identity=27.5142314990512, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI108860692, Length=210, Percent_Identity=37.6190476190476, Blast_Score=131, Evalue=3e-30,
Organism=Escherichia coli, GI1788150, Length=689, Percent_Identity=34.3976777939042, Blast_Score=369, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24583414, Length=722, Percent_Identity=23.9612188365651, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI221510989, Length=730, Percent_Identity=22.7397260273973, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 77206; Mature: 77075

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPPVARTDPQTITQLGRVRIDEYGWMKDENWQAVLRDPSVLRADIAAHLRAENAYTAA
CCCCCCCCCCHHHHHHHHHEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCEEEE
ILAPTESLQATIAAEMKARIREDDTYPALPHGPWRYYMRYAAGAQHPIHARHPEGRPEAE
EECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCE
TILLDVDRMAKGHEYFAVATATHSPDHLLFAHAEDNQGSEVYRVVISDIARGTPVGPAIE
EEEEEHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHH
NCSGNFAFSPDARHLFWTWRDAHGRPTKIFRRRIGTDEDVLVYEETDPGFFIGVEASRSG
CCCCCEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCC
RWIVISASNQDTSESWLIPGGNPEAAAACVEPRRTGVLYSLSHWGDRFAILTNTDGAVDF
CEEEEECCCCCCCCCEEECCCCCHHHHEECCCCCCCEEEEECCCCCEEEEEECCCCCEEE
KLMEAPDTTPGRAHWRDLVPHLPGRYITDCMAFSGHLVWRERRDANTALVVRRVDGTEHV
EEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCEEEEEECCCCCEEEEEEECCCCHHH
LSSDEDAYVLSFSGSFEYDTRELRYVYQSPTTPRQWYAYDMDSRTRHLLKTQEVPSGHDP
HCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCC
RDYRCWRLTATALDGTQVPITVLGLHGTPIDGSAPLLLYGYGSYGHAIEPTFSTGVFSLV
CCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCEECCCHHHHHHHHH
DRGWFYAIAHVRGGSEKGWNWFLGGRGRNKPNSFTDFIACAEHLIADGFTGAGRIVTDGR
CCCEEEEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCC
SAGGMVMGAIANMRPDLFAGIVAVVPFVDELNTMSDTSLPLTPPEWPEWGNPLEDEAAYD
CCCCEEEEHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LIASYAAYEQVAPRPYPAILAIGGLSDPRVTYWEPAKWIARLRAHTTSSRPLLLRINMEA
HHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEECHHHHHHHHHHCCCCCCCEEEEEEECC
GHGGASGRFDALKEAALIQAFAIWAVDTTDHTRTE
CCCCCCCCHHHHHHHHHHEEEEEEEEECCCCCCCC
>Mature Secondary Structure 
TTPPVARTDPQTITQLGRVRIDEYGWMKDENWQAVLRDPSVLRADIAAHLRAENAYTAA
CCCCCCCCCHHHHHHHHHEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCEEEE
ILAPTESLQATIAAEMKARIREDDTYPALPHGPWRYYMRYAAGAQHPIHARHPEGRPEAE
EECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCE
TILLDVDRMAKGHEYFAVATATHSPDHLLFAHAEDNQGSEVYRVVISDIARGTPVGPAIE
EEEEEHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHH
NCSGNFAFSPDARHLFWTWRDAHGRPTKIFRRRIGTDEDVLVYEETDPGFFIGVEASRSG
CCCCCEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCC
RWIVISASNQDTSESWLIPGGNPEAAAACVEPRRTGVLYSLSHWGDRFAILTNTDGAVDF
CEEEEECCCCCCCCCEEECCCCCHHHHEECCCCCCCEEEEECCCCCEEEEEECCCCCEEE
KLMEAPDTTPGRAHWRDLVPHLPGRYITDCMAFSGHLVWRERRDANTALVVRRVDGTEHV
EEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCEEEEEECCCCCEEEEEEECCCCHHH
LSSDEDAYVLSFSGSFEYDTRELRYVYQSPTTPRQWYAYDMDSRTRHLLKTQEVPSGHDP
HCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCC
RDYRCWRLTATALDGTQVPITVLGLHGTPIDGSAPLLLYGYGSYGHAIEPTFSTGVFSLV
CCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCEECCCHHHHHHHHH
DRGWFYAIAHVRGGSEKGWNWFLGGRGRNKPNSFTDFIACAEHLIADGFTGAGRIVTDGR
CCCEEEEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCC
SAGGMVMGAIANMRPDLFAGIVAVVPFVDELNTMSDTSLPLTPPEWPEWGNPLEDEAAYD
CCCCEEEEHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LIASYAAYEQVAPRPYPAILAIGGLSDPRVTYWEPAKWIARLRAHTTSSRPLLLRINMEA
HHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEECHHHHHHHHHHCCCCCCCEEEEEEECC
GHGGASGRFDALKEAALIQAFAIWAVDTTDHTRTE
CCCCCCCCHHHHHHHHHHEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]