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The map label for this gene is clpX

Identifier: 162148814

GI number: 162148814

Start: 3135370

End: 3136629

Strand: Reverse

Name: clpX

Synonym: GDI_3043

Alternate gene names: 162148814

Gene position: 3136629-3135370 (Counterclockwise)

Preceding gene: 162148815

Following gene: 162148813

Centisome position: 79.53

GC content: 63.1

Gene sequence:

>1260_bases
ATGAACAACAAATCCAGCGATTCGAAGAACACACTGTATTGCTCGTTCTGCGGCAAGTCGCAGCATGAGGTCCGGAAGCT
GATCGCTGGTCCGACTGTCTTCATCTGCGACGAATGCGTCGAACTCTGCATGGACATCATCCGTGAGGAGCACAAGACGC
ACCTGGTGAAGTCGCGCGACGGCGTGCCGACTCCCAAGGAGATCTGCAAGGTCCTGGACGATTACGTGATCGGGCAGTTC
TACGCCAAGAAGGTGCTGTCGGTCGCGGTCCACAACCATTACAAGCGCCTGGCCCACAGCCAGAAGAACAACGACGTCGA
AATCGCGAAGTCGAACATCCTGCTGGTCGGGCCGACCGGTTCGGGCAAGACGCTGCTGGCCCAGACGCTGGCGCGTATCC
TCGATGTGCCCTTCACCATGGCCGACGCGACGACGCTGACCGAGGCCGGCTATGTCGGCGAGGATGTGGAGAACATCATC
CTCAAGCTGCTGCAGGCGGCCGACTACAATGTCGAGCGCGCGCAGCGCGGCATCGTCTATATCGACGAAATCGACAAGAT
CTCACGCAAGTCCGACAACCCCTCGATCACCCGCGACGTCAGCGGCGAGGGCGTGCAGCAGGCCCTGCTGAAGATCATGG
AGGGCACGGTGGCCTCGGTTCCGCCCCAGGGCGGCCGCAAGCATCCGCAGCAGGAATTCCTGCAGGTGGACACCACCAAC
ATGCTGTTCATCTGCGGCGGCGCGTTCGCGGGGCTGGACAAGATCATCAGCGCGCGGGGCAAGGGCTCGGGCATCGGATT
CGGCGCGGACGTGCAGTCCCCCGACGAACGGCGCACCGGCGCGATCCTGCGCGACGTCGAACCCGAGGACCTGCTGAAAT
TCGGCCTGATCCCGGAATTCATCGGCCGCCTGCCGGTGGTCGCGACGCTCGAGGACCTCGATGAGGCCGCGCTGATCGAG
ATCCTGACCAAGCCCAAGAACGCGCTGGTGAAGCAGTACGCGCGCCTGTTCCAGATGGAAGGCGTGAAGCTGACCTTCAC
CGACGATGCGCTGAAGCAGGTGGCGCTGCGCGCGATCGCGCGCCGGACCGGCGCGCGCGGCCTGCGCGCGATCATGGAAA
GCATCCTGCTGTCCACGATGTTCGACCTGCCGGGGCTGGAGAACGTGGACGAGGTCGTGATCAACAAGGACGTGGCTGAA
AGCAAGACCAGCCCCGTCTATGTCTACGGCAAGGAGAAGCCGGCCGAACAATCGGCCTGA

Upstream 100 bases:

>100_bases
CGCGGGCTTGGGCAGGGTTGATGAAACCCTGTCGTGAGTCAGGATTTTCGACCCCGGTCCGGGCGCCACGCGGCCCGGCA
TCCCGGGGGTAGGAGCGGTT

Downstream 100 bases:

>100_bases
TTTCCGCTTTCCAGGGGTGCCCCGGCAAGGTCATCCCGTTCCACACGGCGAACCGGGCTCTGCCCGCCTGGTCCGGTTCG
CCTGTTCCTTCCCCGTCATT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNNKSSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVKSRDGVPTPKEICKVLDDYVIGQF
YAKKVLSVAVHNHYKRLAHSQKNNDVEIAKSNILLVGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
MLFICGGAFAGLDKIISARGKGSGIGFGADVQSPDERRTGAILRDVEPEDLLKFGLIPEFIGRLPVVATLEDLDEAALIE
ILTKPKNALVKQYARLFQMEGVKLTFTDDALKQVALRAIARRTGARGLRAIMESILLSTMFDLPGLENVDEVVINKDVAE
SKTSPVYVYGKEKPAEQSA

Sequences:

>Translated_419_residues
MNNKSSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVKSRDGVPTPKEICKVLDDYVIGQF
YAKKVLSVAVHNHYKRLAHSQKNNDVEIAKSNILLVGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
MLFICGGAFAGLDKIISARGKGSGIGFGADVQSPDERRTGAILRDVEPEDLLKFGLIPEFIGRLPVVATLEDLDEAALIE
ILTKPKNALVKQYARLFQMEGVKLTFTDDALKQVALRAIARRTGARGLRAIMESILLSTMFDLPGLENVDEVVINKDVAE
SKTSPVYVYGKEKPAEQSA
>Mature_419_residues
MNNKSSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVKSRDGVPTPKEICKVLDDYVIGQF
YAKKVLSVAVHNHYKRLAHSQKNNDVEIAKSNILLVGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
MLFICGGAFAGLDKIISARGKGSGIGFGADVQSPDERRTGAILRDVEPEDLLKFGLIPEFIGRLPVVATLEDLDEAALIE
ILTKPKNALVKQYARLFQMEGVKLTFTDDALKQVALRAIARRTGARGLRAIMESILLSTMFDLPGLENVDEVVINKDVAE
SKTSPVYVYGKEKPAEQSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=344, Percent_Identity=49.7093023255814, Blast_Score=320, Evalue=1e-87,
Organism=Escherichia coli, GI1786642, Length=425, Percent_Identity=70.3529411764706, Blast_Score=593, Evalue=1e-171,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=43.3962264150943, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982905, Length=310, Percent_Identity=45.8064516129032, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI71982908, Length=310, Percent_Identity=45.8064516129032, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=392, Percent_Identity=36.4795918367347, Blast_Score=239, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=39.2712550607287, Blast_Score=165, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6319704, Length=434, Percent_Identity=39.8617511520737, Blast_Score=274, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24648291, Length=324, Percent_Identity=48.7654320987654, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24648289, Length=324, Percent_Identity=48.7654320987654, Blast_Score=302, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_GLUDA (A9HRV3)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001603275.1
- RefSeq:   YP_002277667.1
- ProteinModelPortal:   A9HRV3
- GeneID:   5791870
- GeneID:   6976766
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_3325
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 45959; Mature: 45959

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKSSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVKSRD
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVPTPKEICKVLDDYVIGQFYAKKVLSVAVHNHYKRLAHSQKNNDVEIAKSNILLVGPTG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCC
SGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIVY
CCHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCEE
IDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
EECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCCC
MLFICGGAFAGLDKIISARGKGSGIGFGADVQSPDERRTGAILRDVEPEDLLKFGLIPEF
EEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCHHCCCCHHHHHHHCCHHHH
IGRLPVVATLEDLDEAALIEILTKPKNALVKQYARLFQMEGVKLTFTDDALKQVALRAIA
HCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH
RRTGARGLRAIMESILLSTMFDLPGLENVDEVVINKDVAESKTSPVYVYGKEKPAEQSA
HHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MNNKSSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVKSRD
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVPTPKEICKVLDDYVIGQFYAKKVLSVAVHNHYKRLAHSQKNNDVEIAKSNILLVGPTG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCC
SGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIVY
CCHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCEE
IDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
EECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCCC
MLFICGGAFAGLDKIISARGKGSGIGFGADVQSPDERRTGAILRDVEPEDLLKFGLIPEF
EEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCHHCCCCHHHHHHHCCHHHH
IGRLPVVATLEDLDEAALIEILTKPKNALVKQYARLFQMEGVKLTFTDDALKQVALRAIA
HCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH
RRTGARGLRAIMESILLSTMFDLPGLENVDEVVINKDVAESKTSPVYVYGKEKPAEQSA
HHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA