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The map label for this gene is fabZ [H]

Identifier: 162148777

GI number: 162148777

Start: 3093618

End: 3094097

Strand: Reverse

Name: fabZ [H]

Synonym: GDI_3006

Alternate gene names: 162148777

Gene position: 3094097-3093618 (Counterclockwise)

Preceding gene: 162148778

Following gene: 162148776

Centisome position: 78.45

GC content: 52.29

Gene sequence:

>480_bases
TTGGATCAAGGAGACAAGGCGTTGAGTTTCTCGTTAAATGGTGAAGAACTGAAGGAATTTCAACCCAATCGATATCCATT
TCTGATGATCGATTACGTGACCGACGTCGAGCCTGGTAAGTATGCCAAGGGCTATAAGCATCTTTCGAATAACGAATGGT
ATTTTCCCATTCATTTCCCCGGTCGGCCAAACATGCCCGGCGCACTTCAACTCGAAGCGATGGCACAGATGCTCACGGTC
GCCATCACGACGCAGGACGGGCTGAAGGGAATGATCACGCACGCACTTCGGCATACGGTACGGTTTCGTAAGGAAGTGCT
GCCGGGTGAAAGCCTGATGATCGAAGCCTATGTGGATTCCTGGCGTCGCGGCGTGTGCAAGGGGCATGCGACAGGCTACA
CGAACGGTACGGTCGCCTGCGAAGCCGAGATGATGATCACCATACCGGAAATCTTCGAGCAGTATCTTCCCAGGAAATGA

Upstream 100 bases:

>100_bases
CACGTTGACGCAGCGTTTTCTGACCTAGATGTTCGGTCCCAAGGTTTGACCACGGAAAATCCAAGGCGCAGGTCGCGGAC
GGCACGACGCGAGACGGGAT

Downstream 100 bases:

>100_bases
GTCGCCTCGACTTCATCATTGTCGGTGCGGGTGCTTCCGGCGCGGCGGTAGCCTGGTCGCTCGTTTCCAGGGGATACAAG
GTCCTTTGTCTGGACCGCGG

Product: (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MDQGDKALSFSLNGEELKEFQPNRYPFLMIDYVTDVEPGKYAKGYKHLSNNEWYFPIHFPGRPNMPGALQLEAMAQMLTV
AITTQDGLKGMITHALRHTVRFRKEVLPGESLMIEAYVDSWRRGVCKGHATGYTNGTVACEAEMMITIPEIFEQYLPRK

Sequences:

>Translated_159_residues
MDQGDKALSFSLNGEELKEFQPNRYPFLMIDYVTDVEPGKYAKGYKHLSNNEWYFPIHFPGRPNMPGALQLEAMAQMLTV
AITTQDGLKGMITHALRHTVRFRKEVLPGESLMIEAYVDSWRRGVCKGHATGYTNGTVACEAEMMITIPEIFEQYLPRK
>Mature_159_residues
MDQGDKALSFSLNGEELKEFQPNRYPFLMIDYVTDVEPGKYAKGYKHLSNNEWYFPIHFPGRPNMPGALQLEAMAQMLTV
AITTQDGLKGMITHALRHTVRFRKEVLPGESLMIEAYVDSWRRGVCKGHATGYTNGTVACEAEMMITIPEIFEQYLPRK

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=138, Percent_Identity=37.6811594202899, Blast_Score=100, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 18135; Mature: 18135

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQGDKALSFSLNGEELKEFQPNRYPFLMIDYVTDVEPGKYAKGYKHLSNNEWYFPIHFP
CCCCCCEEEEECCHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHCCCCCEEEEEECC
GRPNMPGALQLEAMAQMLTVAITTQDGLKGMITHALRHTVRFRKEVLPGESLMIEAYVDS
CCCCCCCCEEHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
WRRGVCKGHATGYTNGTVACEAEMMITIPEIFEQYLPRK
HHHCCCCCCCCCCCCCEEEEECEEEEEHHHHHHHHCCCC
>Mature Secondary Structure
MDQGDKALSFSLNGEELKEFQPNRYPFLMIDYVTDVEPGKYAKGYKHLSNNEWYFPIHFP
CCCCCCEEEEECCHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHCCCCCEEEEEECC
GRPNMPGALQLEAMAQMLTVAITTQDGLKGMITHALRHTVRFRKEVLPGESLMIEAYVDS
CCCCCCCCEEHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
WRRGVCKGHATGYTNGTVACEAEMMITIPEIFEQYLPRK
HHHCCCCCCCCCCCCCEEEEECEEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA