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The map label for this gene is dnaQ [H]

Identifier: 162148736

GI number: 162148736

Start: 3051979

End: 3052659

Strand: Reverse

Name: dnaQ [H]

Synonym: GDI_2964

Alternate gene names: 162148736

Gene position: 3052659-3051979 (Counterclockwise)

Preceding gene: 162148737

Following gene: 162148735

Centisome position: 77.4

GC content: 66.08

Gene sequence:

>681_bases
ATGAAGCGAGCGATCCTGTTCGATACGGAAACGACCGGGCTGGACCCCGCGCGGGGCGACCGGGTGATCGAAATCGCGGC
CCTGGAACTGGTGGGCGACCTGCCGACCGGGCGGCACTTCCATGTGCTGATCCACCCTGACCGCGACATTCCCGAAGAGG
CATCGCGGGTTCACGGCTTCACGCTGGCGGACCTGGAGGGCAAGCCCCGCTTTCACGAAATCGCCGACGATTTCCTGGCC
TTCATCGGGCAGGACGACCTGATTGCCCATAATGCGCGATTCGATTTCGGCTTCCTGAATGCGGAACTGAAGCGCGCCGA
GCGGCCGGCTTTGTCGCTGGACCGGATGGTCGATACGCTGGACATCGCGCGCGACCGCTATCCCGGCCTGCCCAACAGCC
TGGATGCGCTGTGCCGCCGCTTTTCCATCGACCTGTCGGCCCGCACCACCCACAACGCACTGCTGGACTGCCGGCTGCTG
GCGGAAGTCTATCTGGAACTGATGGGCGGCCGGCAGCGCGGACTGGGCCTGACGGTGCAGGATGGCGGGGGGGCGCAGGT
CTCCTATGCCTATGACCTCGCCGGCGCGCGCACCCCGCGCCTTATCGTCCCGACCGAGCAGGAACTGGCGGCGCACGGCC
GTTTTCTGGACAAGATCAAGGAGCCGATCTGGTCGGCCTGA

Upstream 100 bases:

>100_bases
ATGTGATACAGACCGGATTGTCGCGGGCCGATACGATCCGCCGCGTGCGGCGACTGGTCGCACGCCTGCGCGCAACGGCC
GGCCGAAAAGGGGGAGGGGC

Downstream 100 bases:

>100_bases
TGCCGGCGCGGCGGCGGCCGGGGATATGGCGGCTTGGCGCGGGCGTTTCCGATGCCTTATTCTTTTCGGGGTTGTTTCAG
AAGGCCGTATCGAACCAGGA

Product: DNA polymerase III epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKRAILFDTETTGLDPARGDRVIEIAALELVGDLPTGRHFHVLIHPDRDIPEEASRVHGFTLADLEGKPRFHEIADDFLA
FIGQDDLIAHNARFDFGFLNAELKRAERPALSLDRMVDTLDIARDRYPGLPNSLDALCRRFSIDLSARTTHNALLDCRLL
AEVYLELMGGRQRGLGLTVQDGGGAQVSYAYDLAGARTPRLIVPTEQELAAHGRFLDKIKEPIWSA

Sequences:

>Translated_226_residues
MKRAILFDTETTGLDPARGDRVIEIAALELVGDLPTGRHFHVLIHPDRDIPEEASRVHGFTLADLEGKPRFHEIADDFLA
FIGQDDLIAHNARFDFGFLNAELKRAERPALSLDRMVDTLDIARDRYPGLPNSLDALCRRFSIDLSARTTHNALLDCRLL
AEVYLELMGGRQRGLGLTVQDGGGAQVSYAYDLAGARTPRLIVPTEQELAAHGRFLDKIKEPIWSA
>Mature_226_residues
MKRAILFDTETTGLDPARGDRVIEIAALELVGDLPTGRHFHVLIHPDRDIPEEASRVHGFTLADLEGKPRFHEIADDFLA
FIGQDDLIAHNARFDFGFLNAELKRAERPALSLDRMVDTLDIARDRYPGLPNSLDALCRRFSIDLSARTTHNALLDCRLL
AEVYLELMGGRQRGLGLTVQDGGGAQVSYAYDLAGARTPRLIVPTEQELAAHGRFLDKIKEPIWSA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=241, Percent_Identity=40.2489626556017, Blast_Score=158, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25152; Mature: 25152

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAILFDTETTGLDPARGDRVIEIAALELVGDLPTGRHFHVLIHPDRDIPEEASRVHGF
CCCEEEEECCCCCCCCCCCCCEEEEEEEHHHCCCCCCCEEEEEEECCCCCCHHHHHHCCE
TLADLEGKPRFHEIADDFLAFIGQDDLIAHNARFDFGFLNAELKRAERPALSLDRMVDTL
EEECCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCEEHHHHHHHHHCCCCHHHHHHHHHH
DIARDRYPGLPNSLDALCRRFSIDLSARTTHNALLDCRLLAEVYLELMGGRQRGLGLTVQ
HHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
DGGGAQVSYAYDLAGARTPRLIVPTEQELAAHGRFLDKIKEPIWSA
CCCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRAILFDTETTGLDPARGDRVIEIAALELVGDLPTGRHFHVLIHPDRDIPEEASRVHGF
CCCEEEEECCCCCCCCCCCCCEEEEEEEHHHCCCCCCCEEEEEEECCCCCCHHHHHHCCE
TLADLEGKPRFHEIADDFLAFIGQDDLIAHNARFDFGFLNAELKRAERPALSLDRMVDTL
EEECCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCEEHHHHHHHHHCCCCHHHHHHHHHH
DIARDRYPGLPNSLDALCRRFSIDLSARTTHNALLDCRLLAEVYLELMGGRQRGLGLTVQ
HHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
DGGGAQVSYAYDLAGARTPRLIVPTEQELAAHGRFLDKIKEPIWSA
CCCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA