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The map label for this gene is coaE [H]

Identifier: 162148737

GI number: 162148737

Start: 3052656

End: 3053270

Strand: Reverse

Name: coaE [H]

Synonym: GDI_2965

Alternate gene names: 162148737

Gene position: 3053270-3052656 (Counterclockwise)

Preceding gene: 162148738

Following gene: 162148736

Centisome position: 77.41

GC content: 71.87

Gene sequence:

>615_bases
ATGCGGGTTCTGGGCCTGACGGGCGGAATCGGCATGGGAAAATCGACGGTCGCCCGGATGCTGCGCTCCGCCGGCTTCCC
CATCTTCGATGCGGATGCCGCCGTCCATGCCCTTCAGGCGCCGGGCGGGCGGGCGCTGCCGGCGATCGCGCGGCTGGTGC
CCGGATCGGTGCATGATGGCGTGCTGGATCGCGCGGTGCTGCGTCGCGCGGCCATCGCGAACCCCGCGATCCTGAAAGGA
TTGGAGCGGATTCTCCATCCCATGGTGCGCCAGGACCGCGACCGCTTCCTGGCGCGCGCGCGGCGCGCGGGGCATTCCTG
GGCGGTGCTGGACGTGCCGCTGCTGTTCGAAACCGGGGGCGAGCGCGCCTGCGACCGGGTGGTGGTGGTGTCGGCGCCGC
CGGATGTCCAGAAACATCGCGTGGCCCGGCGCCGCGGCATGGCGCCCGACCAGGTGGCGGCGGTGATCGCACGCCAGATG
CCCGATCGCGAAAAGCGGCGGCGGGCCGATGATGTGATACAGACCGGATTGTCGCGGGCCGATACGATCCGCCGCGTGCG
GCGACTGGTCGCACGCCTGCGCGCAACGGCCGGCCGAAAAGGGGGAGGGGCATGA

Upstream 100 bases:

>100_bases
CTGCACCAGGCGCGACTGGGCTTTCGCGAATGGTTCGGCGTCGATCCGGCGGTGGATGCCGATATCCAGGCGCTGCTCGA
CGCCGACCTGGCAGGGTGAC

Downstream 100 bases:

>100_bases
AGCGAGCGATCCTGTTCGATACGGAAACGACCGGGCTGGACCCCGCGCGGGGCGACCGGGTGATCGAAATCGCGGCCCTG
GAACTGGTGGGCGACCTGCC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MRVLGLTGGIGMGKSTVARMLRSAGFPIFDADAAVHALQAPGGRALPAIARLVPGSVHDGVLDRAVLRRAAIANPAILKG
LERILHPMVRQDRDRFLARARRAGHSWAVLDVPLLFETGGERACDRVVVVSAPPDVQKHRVARRRGMAPDQVAAVIARQM
PDREKRRRADDVIQTGLSRADTIRRVRRLVARLRATAGRKGGGA

Sequences:

>Translated_204_residues
MRVLGLTGGIGMGKSTVARMLRSAGFPIFDADAAVHALQAPGGRALPAIARLVPGSVHDGVLDRAVLRRAAIANPAILKG
LERILHPMVRQDRDRFLARARRAGHSWAVLDVPLLFETGGERACDRVVVVSAPPDVQKHRVARRRGMAPDQVAAVIARQM
PDREKRRRADDVIQTGLSRADTIRRVRRLVARLRATAGRKGGGA
>Mature_204_residues
MRVLGLTGGIGMGKSTVARMLRSAGFPIFDADAAVHALQAPGGRALPAIARLVPGSVHDGVLDRAVLRRAAIANPAILKG
LERILHPMVRQDRDRFLARARRAGHSWAVLDVPLLFETGGERACDRVVVVSAPPDVQKHRVARRRGMAPDQVAAVIARQM
PDREKRRRADDVIQTGLSRADTIRRVRRLVARLRATAGRKGGGA

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=189, Percent_Identity=30.1587301587302, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI191252795, Length=189, Percent_Identity=30.1587301587302, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI110227607, Length=200, Percent_Identity=28.5, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227605, Length=200, Percent_Identity=28.5, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI110227603, Length=200, Percent_Identity=28.5, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI110227601, Length=200, Percent_Identity=28.5, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI205277394, Length=200, Percent_Identity=28.5, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786292, Length=176, Percent_Identity=34.0909090909091, Blast_Score=84, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17554944, Length=197, Percent_Identity=29.9492385786802, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320402, Length=206, Percent_Identity=29.6116504854369, Blast_Score=92, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24644728, Length=179, Percent_Identity=28.4916201117318, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22081; Mature: 22081

Theoretical pI: Translated: 12.35; Mature: 12.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGLTGGIGMGKSTVARMLRSAGFPIFDADAAVHALQAPGGRALPAIARLVPGSVHDG
CEEEECCCCCCCCHHHHHHHHHHCCCCEEECHHHHHHHHCCCCCHHHHHHHHCCCCHHHH
VLDRAVLRRAAIANPAILKGLERILHPMVRQDRDRFLARARRAGHSWAVLDVPLLFETGG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCC
ERACDRVVVVSAPPDVQKHRVARRRGMAPDQVAAVIARQMPDREKRRRADDVIQTGLSRA
CHHHCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
DTIRRVRRLVARLRATAGRKGGGA
HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRVLGLTGGIGMGKSTVARMLRSAGFPIFDADAAVHALQAPGGRALPAIARLVPGSVHDG
CEEEECCCCCCCCHHHHHHHHHHCCCCEEECHHHHHHHHCCCCCHHHHHHHHCCCCHHHH
VLDRAVLRRAAIANPAILKGLERILHPMVRQDRDRFLARARRAGHSWAVLDVPLLFETGG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCC
ERACDRVVVVSAPPDVQKHRVARRRGMAPDQVAAVIARQMPDREKRRRADDVIQTGLSRA
CHHHCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
DTIRRVRRLVARLRATAGRKGGGA
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]