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The map label for this gene is ctaC [H]

Identifier: 162148379

GI number: 162148379

Start: 2689943

End: 2690923

Strand: Reverse

Name: ctaC [H]

Synonym: GDI_2597

Alternate gene names: 162148379

Gene position: 2690923-2689943 (Counterclockwise)

Preceding gene: 162148395

Following gene: 162148378

Centisome position: 68.23

GC content: 66.56

Gene sequence:

>981_bases
TTGGCGGAGGGCGCGATGACCTGGCTGCCCGAAGCCTCGTCCCACGCCATGCGGATCGATATCCTGCTGGCCGGACTGGT
GCTCATCAGCCTGGCGGTGCTGGGGCTGGTGTTCGGGCTGATGCTGCTGAACGTGCTGCGTTTCCGTGCCGGCCGCACGA
CGGATATCGTCCGGGCCATCGCGGAACATAAAAGCTGGTGGTTCGAGATTTCCTGGACCTCGGCGACGCTGGTGATCTTC
TTCGGCCTGTTCCTGTGGGCCACGCAGCTTTACGTCGTGGCCTTCCGCCCCCCGGCCGGGGCGATCCAGGTCTATGTCAC
CGGCAAGCAATGGATGTGGAAGATCCAGTATCCGGGCGGCCAGCGCGAAATCAACGCGCTGCATGTGCCGGTGGGCCGGC
CGGTGCAGTTGCTTTTGACATCGGAAGACGTGATCCACGATTTTTCGATCCCGGCGCTGCGGATCAAGCACGACGTGCTG
CCCGGCCGGTATCAGAGCCTGTGGTTCACGGCAACGCAGACCGGATCGTTCCGCCTTTACTGCACCCAGTTCTGCGGCCT
GGCCCATTCCCGCATGACCGGCACGGTGACGGTCCTGAGCGCCGCGGATTATGCCGGCTGGCTGAACGGCACGCCGGCCA
GCGGCAGCCTGGCGATGACGGGCGAGGCCCTGTTCATCCGCAGCGGCTGCAGCGGCTGCCATGCCTCCAGCCGCTATGCC
CCGGATGCGGCGGATACCAGCCGGGCGCCGTCGATGGTCGGGCTGTACGGCAGCCGGGTGACGCTGGCGGACGGCCGCGC
GATCATGGCCGATGCCGCGTTCCTGCATGATTCCATCCTTGATCCGCCGCGCAGGCAGGCTGCCGCCTTCGCGACCGAAA
TGCCGTCCTTTCGCGGCGTCCTGGCCGAGGACGACCTGGCCGCGCTGGTCGCCTACCTGCAGACCCTCTCGCCCGCCCTT
CCTCCAGTTGCAGGGAATTGA

Upstream 100 bases:

>100_bases
TCCAATCCTAGTGTCCGGTTACACTGGCGGTCCGCAAGCTGCTGCGGCTGGGCGCGCTGATGACGGTACTGACCCTGGCC
ACCCTGCTGGGCATGGCCCA

Downstream 100 bases:

>100_bases
CGCGATGTCGGAAAGCTATCTCTGGCAGGACGGAACCCTGCGATCCTGGCTGCTGACGCGTGACCACAAGCGGATCGGCC
TGCTCTATCTGGGCTCGATC

Product: cytochrome c oxidase subunit 2

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MAEGAMTWLPEASSHAMRIDILLAGLVLISLAVLGLVFGLMLLNVLRFRAGRTTDIVRAIAEHKSWWFEISWTSATLVIF
FGLFLWATQLYVVAFRPPAGAIQVYVTGKQWMWKIQYPGGQREINALHVPVGRPVQLLLTSEDVIHDFSIPALRIKHDVL
PGRYQSLWFTATQTGSFRLYCTQFCGLAHSRMTGTVTVLSAADYAGWLNGTPASGSLAMTGEALFIRSGCSGCHASSRYA
PDAADTSRAPSMVGLYGSRVTLADGRAIMADAAFLHDSILDPPRRQAAAFATEMPSFRGVLAEDDLAALVAYLQTLSPAL
PPVAGN

Sequences:

>Translated_326_residues
MAEGAMTWLPEASSHAMRIDILLAGLVLISLAVLGLVFGLMLLNVLRFRAGRTTDIVRAIAEHKSWWFEISWTSATLVIF
FGLFLWATQLYVVAFRPPAGAIQVYVTGKQWMWKIQYPGGQREINALHVPVGRPVQLLLTSEDVIHDFSIPALRIKHDVL
PGRYQSLWFTATQTGSFRLYCTQFCGLAHSRMTGTVTVLSAADYAGWLNGTPASGSLAMTGEALFIRSGCSGCHASSRYA
PDAADTSRAPSMVGLYGSRVTLADGRAIMADAAFLHDSILDPPRRQAAAFATEMPSFRGVLAEDDLAALVAYLQTLSPAL
PPVAGN
>Mature_325_residues
AEGAMTWLPEASSHAMRIDILLAGLVLISLAVLGLVFGLMLLNVLRFRAGRTTDIVRAIAEHKSWWFEISWTSATLVIFF
GLFLWATQLYVVAFRPPAGAIQVYVTGKQWMWKIQYPGGQREINALHVPVGRPVQLLLTSEDVIHDFSIPALRIKHDVLP
GRYQSLWFTATQTGSFRLYCTQFCGLAHSRMTGTVTVLSAADYAGWLNGTPASGSLAMTGEALFIRSGCSGCHASSRYAP
DAADTSRAPSMVGLYGSRVTLADGRAIMADAAFLHDSILDPPRRQAAAFATEMPSFRGVLAEDDLAALVAYLQTLSPALP
PVAGN

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=146, Percent_Identity=26.7123287671233, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6226540, Length=206, Percent_Identity=25.7281553398058, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 35347; Mature: 35216

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00078 COX2 ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGAMTWLPEASSHAMRIDILLAGLVLISLAVLGLVFGLMLLNVLRFRAGRTTDIVRAI
CCCCCCEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AEHKSWWFEISWTSATLVIFFGLFLWATQLYVVAFRPPAGAIQVYVTGKQWMWKIQYPGG
HHCCCEEEEEEECHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEECCEEEEEEECCCC
QREINALHVPVGRPVQLLLTSEDVIHDFSIPALRIKHDVLPGRYQSLWFTATQTGSFRLY
CCEEEEEECCCCCCEEEEEECCHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCEEEE
CTQFCGLAHSRMTGTVTVLSAADYAGWLNGTPASGSLAMTGEALFIRSGCSGCHASSRYA
HHHHHCCHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCC
PDAADTSRAPSMVGLYGSRVTLADGRAIMADAAFLHDSILDPPRRQAAAFATEMPSFRGV
CCCCCCCCCCCEEEECCCEEEEECCCEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCC
LAEDDLAALVAYLQTLSPALPPVAGN
CCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AEGAMTWLPEASSHAMRIDILLAGLVLISLAVLGLVFGLMLLNVLRFRAGRTTDIVRAI
CCCCCEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AEHKSWWFEISWTSATLVIFFGLFLWATQLYVVAFRPPAGAIQVYVTGKQWMWKIQYPGG
HHCCCEEEEEEECHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEECCEEEEEEECCCC
QREINALHVPVGRPVQLLLTSEDVIHDFSIPALRIKHDVLPGRYQSLWFTATQTGSFRLY
CCEEEEEECCCCCCEEEEEECCHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCEEEE
CTQFCGLAHSRMTGTVTVLSAADYAGWLNGTPASGSLAMTGEALFIRSGCSGCHASSRYA
HHHHHCCHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCC
PDAADTSRAPSMVGLYGSRVTLADGRAIMADAAFLHDSILDPPRRQAAAFATEMPSFRGV
CCCCCCCCCCCEEEECCCEEEEECCCEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCC
LAEDDLAALVAYLQTLSPALPPVAGN
CCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]