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The map label for this gene is ybeC [H]

Identifier: 162148354

GI number: 162148354

Start: 2664192

End: 2665871

Strand: Reverse

Name: ybeC [H]

Synonym: GDI_2571

Alternate gene names: 162148354

Gene position: 2665871-2664192 (Counterclockwise)

Preceding gene: 162148355

Following gene: 162148353

Centisome position: 67.59

GC content: 68.57

Gene sequence:

>1680_bases
TTGCGTCCGGACGCGGAACGATGTTGGTTGGGCGAATCCGCGTGCGATTCGCACCCACCCCCGCCCGACTGCCGGAGAAG
CCCAGACGTGTCACCCCACCTGAATCGCGCCCTTGGCCCCTGGCAACTGATGTTCACGGGGCTGAGCGCCATGATCGGGT
CGGGCTGGCTGTTCGGGGCCCAGCGCGCGGCCGCGACGGCGGGGCCGGCGGCCAGCCTGGCCTGGCTGCTGGGCGCGGTC
ATCGCGCTGGCGATCGCGGGCGTGGCCACCGAACTGGGGGGCATGTTCCCGGTGGCGGGCGGCATGGTGCGCTACGCCAA
CCTGACCCACGGTCCGCTGGTCGGCTTCATGGCCGCCAGCGCGAACTGGCTGTCGATCGTCAGCGTCGTACCGGTCGAGG
CCGAGGCGTCGGTGCAGTATATGAGTTCCTGGTCCTTTCCCTGGGCGCGGGGGCTGTATCATGACGGCGTGCTGACGCCG
CCGGGCCTGATGGCGGCGGCGGTGCTGGTGGTGGTCTATTTCCTGCTGAATTTCTGGAGCGTGCGGTTCTTCGCGCGCTT
CAACGCCATGATCACGGTCTTCAAGCTGGTGGTGCCGGCCGCCACCGCGCTGGCGCTGATGGCCAGCAGCTTCCGTGCCG
GCAACCTGGTGGGCGATGGTGCCGGCGGGTTCATGCCCTATGGCCTGTCGGGCATCCTGACGGCGGTTTCGACCTCGGGC
ATCGTCTTCGCCTTCAACGGGTTCCAGAGCCCGCTGAACCTGGCGGGGGAGGCGCGCAATCCCGCGCGCAGCATCCCCTT
CGCCGTGCTGGGATCGGTCGTGCTGGCGACCGTGATCTACCTGCTGCTGCAATGCGCCTACCTGGGCGCCGTGCGGCCGG
GGGCGGGGGGATGGGCCGGCCTGTCCTTTTCCTCGCCCTTCGCGCAGCTTGCCATCGCCTTCAACCTCAACTGGCTGGCG
ATGCTGCTGTATTTCGATGCCTTCCTCGCCCCCAGCGGCGCCGGGGCGACCCATCTGGCCAGCAGCACGCGCATGACGCT
GGGCATGCAGCGCAACGGCACGATGCCCGACCTGCTGGGGCGCATCCATCCGCTCTACGGCGTGCCGCGCCCGGCGCTGT
GGTTCAACCTGGGCGTGGCGTTCATCTTCCTGTTCTGCTTTCGCGGGTGGGGTATCCTGGCCTCGGTCATTTCGGTCTGT
ACCGTGATTTCCTACATGATGCTGCCGATCGCGGCCCTGGCGCTGCGGCGGACGCTGCCGGATCGTCTCCGGCCGGTGCG
GGTGCCGGCCATGCGGGTGGTGGGCGCGCTGGCCTTCATGTTTTCCTCGCTGCTGCTCTATTGGGCGCGATGGCCGCTCA
GCGGCGACATCATCCTGCTGATGCTGATGTTCCTGCCGCTCTATGCCTGGTTCCGCCGGCATGACGGGTGGGCGCGGCAC
CGTGCGGCCTTCCGCCATGCGGTCTGGTTCATGGCCTACCTGCCGACCATCGCGGCGCTGTCCTATGGCGGCAGTACGGC
GTTCGGCGGGCGGGGCTGGATTCCCTATGGCTGGGACCTTGCGGTGGTGGCGGTCGTTTCTCTGCTGTTCTGCGAATGGG
GGGTGCGCAGCGCCGTGCCCGTCCCAGACGTCTCGGTAATGGACGCGCAGGACGACGTGCCGGCCATGGAAGGGCACTGA

Upstream 100 bases:

>100_bases
AAGACCCGGAAATGGCCCGAGGTCCGCGCGGCGATCGCCGGGATGGTGGAGGCCGCGCGCCGGATGCGGGCGGGCGACGC
GACCGGCTGACCCCGGCCTG

Downstream 100 bases:

>100_bases
GAAACGTATTTCGTTCCCTCAAACTATTGTGCGAGACAGGCGCCGCGCGCCCCCTTGTTCCGTCTTGTGGGCCCACCAAC
TCAGGTCTCGTTCATCAGCG

Product: amino acid permease

Products: Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MRPDAERCWLGESACDSHPPPPDCRRSPDVSPHLNRALGPWQLMFTGLSAMIGSGWLFGAQRAAATAGPAASLAWLLGAV
IALAIAGVATELGGMFPVAGGMVRYANLTHGPLVGFMAASANWLSIVSVVPVEAEASVQYMSSWSFPWARGLYHDGVLTP
PGLMAAAVLVVVYFLLNFWSVRFFARFNAMITVFKLVVPAATALALMASSFRAGNLVGDGAGGFMPYGLSGILTAVSTSG
IVFAFNGFQSPLNLAGEARNPARSIPFAVLGSVVLATVIYLLLQCAYLGAVRPGAGGWAGLSFSSPFAQLAIAFNLNWLA
MLLYFDAFLAPSGAGATHLASSTRMTLGMQRNGTMPDLLGRIHPLYGVPRPALWFNLGVAFIFLFCFRGWGILASVISVC
TVISYMMLPIAALALRRTLPDRLRPVRVPAMRVVGALAFMFSSLLLYWARWPLSGDIILLMLMFLPLYAWFRRHDGWARH
RAAFRHAVWFMAYLPTIAALSYGGSTAFGGRGWIPYGWDLAVVAVVSLLFCEWGVRSAVPVPDVSVMDAQDDVPAMEGH

Sequences:

>Translated_559_residues
MRPDAERCWLGESACDSHPPPPDCRRSPDVSPHLNRALGPWQLMFTGLSAMIGSGWLFGAQRAAATAGPAASLAWLLGAV
IALAIAGVATELGGMFPVAGGMVRYANLTHGPLVGFMAASANWLSIVSVVPVEAEASVQYMSSWSFPWARGLYHDGVLTP
PGLMAAAVLVVVYFLLNFWSVRFFARFNAMITVFKLVVPAATALALMASSFRAGNLVGDGAGGFMPYGLSGILTAVSTSG
IVFAFNGFQSPLNLAGEARNPARSIPFAVLGSVVLATVIYLLLQCAYLGAVRPGAGGWAGLSFSSPFAQLAIAFNLNWLA
MLLYFDAFLAPSGAGATHLASSTRMTLGMQRNGTMPDLLGRIHPLYGVPRPALWFNLGVAFIFLFCFRGWGILASVISVC
TVISYMMLPIAALALRRTLPDRLRPVRVPAMRVVGALAFMFSSLLLYWARWPLSGDIILLMLMFLPLYAWFRRHDGWARH
RAAFRHAVWFMAYLPTIAALSYGGSTAFGGRGWIPYGWDLAVVAVVSLLFCEWGVRSAVPVPDVSVMDAQDDVPAMEGH
>Mature_559_residues
MRPDAERCWLGESACDSHPPPPDCRRSPDVSPHLNRALGPWQLMFTGLSAMIGSGWLFGAQRAAATAGPAASLAWLLGAV
IALAIAGVATELGGMFPVAGGMVRYANLTHGPLVGFMAASANWLSIVSVVPVEAEASVQYMSSWSFPWARGLYHDGVLTP
PGLMAAAVLVVVYFLLNFWSVRFFARFNAMITVFKLVVPAATALALMASSFRAGNLVGDGAGGFMPYGLSGILTAVSTSG
IVFAFNGFQSPLNLAGEARNPARSIPFAVLGSVVLATVIYLLLQCAYLGAVRPGAGGWAGLSFSSPFAQLAIAFNLNWLA
MLLYFDAFLAPSGAGATHLASSTRMTLGMQRNGTMPDLLGRIHPLYGVPRPALWFNLGVAFIFLFCFRGWGILASVISVC
TVISYMMLPIAALALRRTLPDRLRPVRVPAMRVVGALAFMFSSLLLYWARWPLSGDIILLMLMFLPLYAWFRRHDGWARH
RAAFRHAVWFMAYLPTIAALSYGGSTAFGGRGWIPYGWDLAVVAVVSLLFCEWGVRSAVPVPDVSVMDAQDDVPAMEGH

Specific function: Uptake of an yet unknown amino-acid with the concomitant import of a proton [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family [H]

Homologues:

Organism=Escherichia coli, GI1786789, Length=417, Percent_Identity=25.8992805755396, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786302, Length=411, Percent_Identity=24.0875912408759, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786602, Length=423, Percent_Identity=25.0591016548463, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082250, Length=487, Percent_Identity=24.6406570841889, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87081915, Length=421, Percent_Identity=22.5653206650831, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI87081708, Length=358, Percent_Identity=24.8603351955307, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789017, Length=419, Percent_Identity=21.9570405727924, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=489, Percent_Identity=25.1533742331288, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=384, Percent_Identity=24.4791666666667, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17532491, Length=275, Percent_Identity=24.3636363636364, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24667468, Length=432, Percent_Identity=25.2314814814815, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI221512776, Length=443, Percent_Identity=23.7020316027088, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666159, Length=443, Percent_Identity=23.7020316027088, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 60023; Mature: 60023

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPDAERCWLGESACDSHPPPPDCRRSPDVSPHLNRALGPWQLMFTGLSAMIGSGWLFGA
CCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCHHHCC
QRAAATAGPAASLAWLLGAVIALAIAGVATELGGMFPVAGGMVRYANLTHGPLVGFMAAS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHCC
ANWLSIVSVVPVEAEASVQYMSSWSFPWARGLYHDGVLTPPGLMAAAVLVVVYFLLNFWS
CCHHHHHHHCCCCCHHHHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VRFFARFNAMITVFKLVVPAATALALMASSFRAGNLVGDGAGGFMPYGLSGILTAVSTSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHCCC
IVFAFNGFQSPLNLAGEARNPARSIPFAVLGSVVLATVIYLLLQCAYLGAVRPGAGGWAG
EEEEECCCCCCHHHCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LSFSSPFAQLAIAFNLNWLAMLLYFDAFLAPSGAGATHLASSTRMTLGMQRNGTMPDLLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHEEECCCCCCCHHHHH
RIHPLYGVPRPALWFNLGVAFIFLFCFRGWGILASVISVCTVISYMMLPIAALALRRTLP
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLRPVRVPAMRVVGALAFMFSSLLLYWARWPLSGDIILLMLMFLPLYAWFRRHDGWARH
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
RAAFRHAVWFMAYLPTIAALSYGGSTAFGGRGWIPYGWDLAVVAVVSLLFCEWGVRSAVP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
VPDVSVMDAQDDVPAMEGH
CCCCEEECCCCCCCCCCCC
>Mature Secondary Structure
MRPDAERCWLGESACDSHPPPPDCRRSPDVSPHLNRALGPWQLMFTGLSAMIGSGWLFGA
CCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCHHHCC
QRAAATAGPAASLAWLLGAVIALAIAGVATELGGMFPVAGGMVRYANLTHGPLVGFMAAS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHCC
ANWLSIVSVVPVEAEASVQYMSSWSFPWARGLYHDGVLTPPGLMAAAVLVVVYFLLNFWS
CCHHHHHHHCCCCCHHHHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VRFFARFNAMITVFKLVVPAATALALMASSFRAGNLVGDGAGGFMPYGLSGILTAVSTSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHCCC
IVFAFNGFQSPLNLAGEARNPARSIPFAVLGSVVLATVIYLLLQCAYLGAVRPGAGGWAG
EEEEECCCCCCHHHCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LSFSSPFAQLAIAFNLNWLAMLLYFDAFLAPSGAGATHLASSTRMTLGMQRNGTMPDLLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHEEECCCCCCCHHHHH
RIHPLYGVPRPALWFNLGVAFIFLFCFRGWGILASVISVCTVISYMMLPIAALALRRTLP
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLRPVRVPAMRVVGALAFMFSSLLLYWARWPLSGDIILLMLMFLPLYAWFRRHDGWARH
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
RAAFRHAVWFMAYLPTIAALSYGGSTAFGGRGWIPYGWDLAVVAVVSLLFCEWGVRSAVP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
VPDVSVMDAQDDVPAMEGH
CCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] + L-phenylalanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12730183 [H]