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The map label for this gene is nuoN [H]

Identifier: 162148242

GI number: 162148242

Start: 2548110

End: 2549591

Strand: Reverse

Name: nuoN [H]

Synonym: GDI_2459

Alternate gene names: 162148242

Gene position: 2549591-2548110 (Counterclockwise)

Preceding gene: 162148243

Following gene: 162148241

Centisome position: 64.64

GC content: 72.06

Gene sequence:

>1482_bases
ATGACTCATGACGCCATGACCATATTGCCCGCCATGCCGCCGCCCGTGCTGGTCCTGGGGGCCGGCATCCTGGCCCTGCT
GGCCTGCCTGGCATGGCGGCGCGCGGCCATGGGATGGGTGGCCGCCGGCACGCTGGTCCTGGCGCTGGCCAGCCTGGCCT
TCGCCGGTGCGGGCGGCCCGCCCGTCGCGGACGGGGCCGCCCTGTTCGCGGCCGATGGGTGGTTCGTCTATGGCGCCGGG
CTGATCGTGCTGTCGTCGGGCGGCGTGCTGGCCATGGCGTGGCGCCGCCTGGGGGATGACGGCGCGGGCGAGGGGCACCT
GCTGCTGCTGCTGGGCACGCTGGGCGCCGTGATCGTGGCGGGCAGCGCGAACATGATCGCGCTGTTCCTGGGGCTGGAAA
CGCTCAGCCTGTCCCTGCCGGGGCTGGTCGCCTACCGGCCCGGCCGGCCGGAAGCGGTCGAGGCCGCGATGAAATACCTG
ATGCTGTCCGGTGTCTCGACCGCGATCCTGCTGTTCGGACTGGCATTGTCCTACGACCAGGGCGGCACGCTGCGCTTCGC
CGCGCTGGATGGCGGGGCGCATGGAATCCTGGGGCTGGCGGCCAGCATCATGGTCCTGACGGGCCTGTTCTTCAAACTGT
CGGTCGTGCCGTTCCATTTGTGGCTGCCCGACGTGATCGAGGGCGCGCCGCTGCCGGTCGCGGCCTTCATCGCCGTCGTC
TCCAAGATCGCGCTGTTCGTCGCGCTGGCCCATTACGCCGCGGGCGTGGACCTGGCCGGCGCCGGACCCCTGTCCACCGA
ACTGACCGCGGTGGCGGTGCTGAGCATGCTGGGCGGCAACCTGCTGGCCCTGCGGCAGACCAACCTGAAGCGGCTGCTGG
CGGGGTCGTCCATCGCCCATATCGGGTACCTGCTGGTGGCGCTGCTGTCGCCCGGGCCGTTCGGCGCGGGCAGCGCCGCC
TTCTATCTGGCGGCCTATTCGGCGGCCACGCTGGGGGCGTTCGCGGTGTTGGGCGCGGTGGGGCAGGGTGGCGAGGACAT
GGCGGACCTCGATTCGTGGCGCGGCATGTTCCACCGGCATCCGGCGGTGGCCTGCGCGCTGTCCGTCATGCTGCTGTCGC
TGGCGGGCATTCCCCCGGTCGCCGGCTTCTTCGCCAAGGCGTATATCGTCACGGCGGGCATGTCGGCCCACCGCACGGTC
CTGTTGGCGGCCCTGATCGTGGGCAGCGTCATCGGCCTGTACTATTACCTGAACGTGGCGCGGGTCATGATGGCGTCCGC
GCCGGGCGTCCTGCCGCGCGAAGGCGCCCCGGCGGGGCGCGGACAGGCCGGCCTGGTCGCGGTGCTGGCGGTGGTCGTGG
TGATGATCGGCCTGCTGCCCGGCCCGCTGGTGCGGTGGAGCGGCGCGCTGGTCGCGGCGGCGGGGTCTCACGAATTTCTG
TTCGCCGCCGCCCACGTGCCGGGCACCGTCCCCTTCCGTTAG

Upstream 100 bases:

>100_bases
CGGTACTGGGCGGCACGGTCGCGCTGCTGATCGGCCTGGGCCTGTGCCCGCAGCCGGTGCTGGACCTGTCGCAGCCCGCC
CGCCCGACGGTGTCCGCGCC

Downstream 100 bases:

>100_bases
CCGTCCGGCTTGCCACATCACCCTTGCGCGCCCCCGATCGGGGACGCGGGAGGATGCATCATGACGGCTTCTGTTCTTCA
GGTGCTGGACCGCAAGGGCC

Product: NADH-quinone oxidoreductase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MTHDAMTILPAMPPPVLVLGAGILALLACLAWRRAAMGWVAAGTLVLALASLAFAGAGGPPVADGAALFAADGWFVYGAG
LIVLSSGGVLAMAWRRLGDDGAGEGHLLLLLGTLGAVIVAGSANMIALFLGLETLSLSLPGLVAYRPGRPEAVEAAMKYL
MLSGVSTAILLFGLALSYDQGGTLRFAALDGGAHGILGLAASIMVLTGLFFKLSVVPFHLWLPDVIEGAPLPVAAFIAVV
SKIALFVALAHYAAGVDLAGAGPLSTELTAVAVLSMLGGNLLALRQTNLKRLLAGSSIAHIGYLLVALLSPGPFGAGSAA
FYLAAYSAATLGAFAVLGAVGQGGEDMADLDSWRGMFHRHPAVACALSVMLLSLAGIPPVAGFFAKAYIVTAGMSAHRTV
LLAALIVGSVIGLYYYLNVARVMMASAPGVLPREGAPAGRGQAGLVAVLAVVVVMIGLLPGPLVRWSGALVAAAGSHEFL
FAAAHVPGTVPFR

Sequences:

>Translated_493_residues
MTHDAMTILPAMPPPVLVLGAGILALLACLAWRRAAMGWVAAGTLVLALASLAFAGAGGPPVADGAALFAADGWFVYGAG
LIVLSSGGVLAMAWRRLGDDGAGEGHLLLLLGTLGAVIVAGSANMIALFLGLETLSLSLPGLVAYRPGRPEAVEAAMKYL
MLSGVSTAILLFGLALSYDQGGTLRFAALDGGAHGILGLAASIMVLTGLFFKLSVVPFHLWLPDVIEGAPLPVAAFIAVV
SKIALFVALAHYAAGVDLAGAGPLSTELTAVAVLSMLGGNLLALRQTNLKRLLAGSSIAHIGYLLVALLSPGPFGAGSAA
FYLAAYSAATLGAFAVLGAVGQGGEDMADLDSWRGMFHRHPAVACALSVMLLSLAGIPPVAGFFAKAYIVTAGMSAHRTV
LLAALIVGSVIGLYYYLNVARVMMASAPGVLPREGAPAGRGQAGLVAVLAVVVVMIGLLPGPLVRWSGALVAAAGSHEFL
FAAAHVPGTVPFR
>Mature_492_residues
THDAMTILPAMPPPVLVLGAGILALLACLAWRRAAMGWVAAGTLVLALASLAFAGAGGPPVADGAALFAADGWFVYGAGL
IVLSSGGVLAMAWRRLGDDGAGEGHLLLLLGTLGAVIVAGSANMIALFLGLETLSLSLPGLVAYRPGRPEAVEAAMKYLM
LSGVSTAILLFGLALSYDQGGTLRFAALDGGAHGILGLAASIMVLTGLFFKLSVVPFHLWLPDVIEGAPLPVAAFIAVVS
KIALFVALAHYAAGVDLAGAGPLSTELTAVAVLSMLGGNLLALRQTNLKRLLAGSSIAHIGYLLVALLSPGPFGAGSAAF
YLAAYSAATLGAFAVLGAVGQGGEDMADLDSWRGMFHRHPAVACALSVMLLSLAGIPPVAGFFAKAYIVTAGMSAHRTVL
LAALIVGSVIGLYYYLNVARVMMASAPGVLPREGAPAGRGQAGLVAVLAVVVVMIGLLPGPLVRWSGALVAAAGSHEFLF
AAAHVPGTVPFR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=329, Percent_Identity=21.8844984802432, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI145693160, Length=465, Percent_Identity=39.7849462365591, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI1788831, Length=400, Percent_Identity=28, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788614, Length=335, Percent_Identity=27.1641791044776, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788829, Length=343, Percent_Identity=27.6967930029155, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 49720; Mature: 49588

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDAMTILPAMPPPVLVLGAGILALLACLAWRRAAMGWVAAGTLVLALASLAFAGAGGP
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVADGAALFAADGWFVYGAGLIVLSSGGVLAMAWRRLGDDGAGEGHLLLLLGTLGAVIVA
CCCCCCEEEEECCEEEEECCEEEEECCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHEEC
GSANMIALFLGLETLSLSLPGLVAYRPGRPEAVEAAMKYLMLSGVSTAILLFGLALSYDQ
CCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHEECC
GGTLRFAALDGGAHGILGLAASIMVLTGLFFKLSVVPFHLWLPDVIEGAPLPVAAFIAVV
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHH
SKIALFVALAHYAAGVDLAGAGPLSTELTAVAVLSMLGGNLLALRQTNLKRLLAGSSIAH
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCHHHH
IGYLLVALLSPGPFGAGSAAFYLAAYSAATLGAFAVLGAVGQGGEDMADLDSWRGMFHRH
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
PAVACALSVMLLSLAGIPPVAGFFAKAYIVTAGMSAHRTVLLAALIVGSVIGLYYYLNVA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RVMMASAPGVLPREGAPAGRGQAGLVAVLAVVVVMIGLLPGPLVRWSGALVAAAGSHEFL
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEECCCCCEE
FAAAHVPGTVPFR
EEEECCCCCCCCC
>Mature Secondary Structure 
THDAMTILPAMPPPVLVLGAGILALLACLAWRRAAMGWVAAGTLVLALASLAFAGAGGP
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVADGAALFAADGWFVYGAGLIVLSSGGVLAMAWRRLGDDGAGEGHLLLLLGTLGAVIVA
CCCCCCEEEEECCEEEEECCEEEEECCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHEEC
GSANMIALFLGLETLSLSLPGLVAYRPGRPEAVEAAMKYLMLSGVSTAILLFGLALSYDQ
CCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHEECC
GGTLRFAALDGGAHGILGLAASIMVLTGLFFKLSVVPFHLWLPDVIEGAPLPVAAFIAVV
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHH
SKIALFVALAHYAAGVDLAGAGPLSTELTAVAVLSMLGGNLLALRQTNLKRLLAGSSIAH
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCHHHH
IGYLLVALLSPGPFGAGSAAFYLAAYSAATLGAFAVLGAVGQGGEDMADLDSWRGMFHRH
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
PAVACALSVMLLSLAGIPPVAGFFAKAYIVTAGMSAHRTVLLAALIVGSVIGLYYYLNVA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RVMMASAPGVLPREGAPAGRGQAGLVAVLAVVVVMIGLLPGPLVRWSGALVAAAGSHEFL
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEECCCCCEE
FAAAHVPGTVPFR
EEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA