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The map label for this gene is 162148123

Identifier: 162148123

GI number: 162148123

Start: 2408826

End: 2409386

Strand: Reverse

Name: 162148123

Synonym: GDI_2340

Alternate gene names: NA

Gene position: 2409386-2408826 (Counterclockwise)

Preceding gene: 162148124

Following gene: 162148122

Centisome position: 61.09

GC content: 67.91

Gene sequence:

>561_bases
ATGGACCGGCCGCCTTGCGTCATCATCCTCAACGGTGTCGGCAGCGTCGGCAAGAGTTCCGTCGCGCGGGCGCTTCAGGG
GCTGCTGGACCGCCCGTTCCTGCATGTCGCGATGGACGATTTCGTCTCCATGCTGCCGCCACGGATGCTCGATCATCCGG
ATGGCATGCAATTCGTCCCCGAAACCCGGGACGGGCATCCCTCGATCGCCATTCGCGGCGGGGCGGTGATGGCACGGGCG
ATGCGCGGTATGCGCCATGCCGTGGCCGCCATGGCGGGGCAGGGGAACGACCTGATCGTGGACGACGTGATGCTGGATGC
GGCCGACGCGCGCGACTATCGGGCGCTGCTGGCGGGCTGCGTCGTGCATCTGGTCGGGCTGTTTGCGCCGCTGGCGATTT
TGGAAGCGCGGGAGCGCGCGCGGGGTGATCGGCGGATCGGCCTGGCGCGCTGGCAGTATGATCGGGTGCATCGCGGCATG
GCGTACGACCTGGAACTGGACACGGTTCGCATGACGCCCGGACAGTCGGCGCACAGTATCCGCGACGCGTTCGGCCTGTA
A

Upstream 100 bases:

>100_bases
CCAGGCCGGACACAGGATGATGGTCGCCGGGGCCATGAAGCAGGCCATCGACCGTTATTTCGCCTCGGCCAACGGCATCA
CGCACCTGACCGGCTGAAAT

Downstream 100 bases:

>100_bases
TCCGCCGGATACGGATGGACGGGCCTTTTCTGTTGCAATCGGCGGATCGGCCTGTATGGTGCCGGCCATGGATTCCGCAA
CGATCATGACGGCAGGCTTG

Product: chloramphenicol 3-O phosphotransferase

Products: NA

Alternate protein names: CPT [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MDRPPCVIILNGVGSVGKSSVARALQGLLDRPFLHVAMDDFVSMLPPRMLDHPDGMQFVPETRDGHPSIAIRGGAVMARA
MRGMRHAVAAMAGQGNDLIVDDVMLDAADARDYRALLAGCVVHLVGLFAPLAILEARERARGDRRIGLARWQYDRVHRGM
AYDLELDTVRMTPGQSAHSIRDAFGL

Sequences:

>Translated_186_residues
MDRPPCVIILNGVGSVGKSSVARALQGLLDRPFLHVAMDDFVSMLPPRMLDHPDGMQFVPETRDGHPSIAIRGGAVMARA
MRGMRHAVAAMAGQGNDLIVDDVMLDAADARDYRALLAGCVVHLVGLFAPLAILEARERARGDRRIGLARWQYDRVHRGM
AYDLELDTVRMTPGQSAHSIRDAFGL
>Mature_186_residues
MDRPPCVIILNGVGSVGKSSVARALQGLLDRPFLHVAMDDFVSMLPPRMLDHPDGMQFVPETRDGHPSIAIRGGAVMARA
MRGMRHAVAAMAGQGNDLIVDDVMLDAADARDYRALLAGCVVHLVGLFAPLAILEARERARGDRRIGLARWQYDRVHRGM
AYDLELDTVRMTPGQSAHSIRDAFGL

Specific function: Inactivates chloramphenicol by catalyzing the transfer of the gamma-phosphate of ATP to the antibiotic's C-3' hydroxyl group [H]

COG id: COG3896

COG function: function code V; Chloramphenicol 3-O-phosphotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2636 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012853 [H]

Pfam domain/function: PF07931 CPT [H]

EC number: NA

Molecular weight: Translated: 20294; Mature: 20294

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRPPCVIILNGVGSVGKSSVARALQGLLDRPFLHVAMDDFVSMLPPRMLDHPDGMQFVP
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCC
ETRDGHPSIAIRGGAVMARAMRGMRHAVAAMAGQGNDLIVDDVMLDAADARDYRALLAGC
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCHHHHHHHHHHH
VVHLVGLFAPLAILEARERARGDRRIGLARWQYDRVHRGMAYDLELDTVRMTPGQSAHSI
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHH
RDAFGL
HHHHCC
>Mature Secondary Structure
MDRPPCVIILNGVGSVGKSSVARALQGLLDRPFLHVAMDDFVSMLPPRMLDHPDGMQFVP
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCC
ETRDGHPSIAIRGGAVMARAMRGMRHAVAAMAGQGNDLIVDDVMLDAADARDYRALLAGC
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCHHHHHHHHHHH
VVHLVGLFAPLAILEARERARGDRRIGLARWQYDRVHRGMAYDLELDTVRMTPGQSAHSI
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHH
RDAFGL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592948; 10835366 [H]