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The map label for this gene is merD [H]

Identifier: 162148116

GI number: 162148116

Start: 2400286

End: 2401440

Strand: Reverse

Name: merD [H]

Synonym: GDI_2333

Alternate gene names: 162148116

Gene position: 2401440-2400286 (Counterclockwise)

Preceding gene: 162148117

Following gene: 162148113

Centisome position: 60.89

GC content: 65.63

Gene sequence:

>1155_bases
ATGAATTTCCAGAAGCGCCTCCTGCGCGCCGAACCCAATTTCCGCATCCTGGCCAAGCTGTGGCAGGTCAACTGGCTGTA
CGTGCTGCTGATCTGCGTGCTGGCGGGGGTGGGGTACGGCGCGCTCTATTCCGCGGCGGGCGGGTCGTCCCGTCCGTTCG
CCGGTCCGCAGACCATCCGCTTCGCCTTCGGCATGGTGATGATGATCTGCGTCGCGCTGACCAGCCCGCGCGTTCTGGTC
CGCCTGGCCTGGCCGCTCTACGGGCTATCGCTGCTGCTGCTGGTCGCGGTGCTGCGGATGGGCCATGTCGGCAAGGGGGC
GGAACGCTGGCTGATCATCGGCGGGATGCAGGTCCAGCCCTCGGAACTGGCCAAGATCGCACTGGTGCTGGTGCTGGCGA
CGTGGTTCCACCGCATCAGCTACCGCAGGATGGTCAATCCGCTCTACCTGCTGCCGCCCGCGCTGATGGTGCTGCTGCCG
GTGGGGCTGGTGCTGAAGGAGCCCAACCTGGGCACCGCCGTCATCATCGGCGTGGTGGGGGCCACGATCTTCTTCGCCGC
CGGGATGCGGCTGTGGCAGATCGTACTGCTACTGGCACCGCTGCCGTTGCTGGGCAAGTTCGCCTACGCCCACCTGCATG
ACTACCAGAAGGCGCGGATCACCACCTTCCTGCACCCCGAAAGCGACCCGCTGGGCGCGGGCTATAACATCATCCAGTCG
AAGATCGCGCTGGGGTCGGGCGGGATGTGGGGGCAGGGCTACCTGCATGGCACGCAGGGGCAACTGAACTTCCTGCCGGA
AAAGCAGACCGACTTCATCTTCACCATGATCGCCGAGGAATGGGGCTATGTCGGCGGGATCGTGGTCATCGGGCTGCTGA
TGCTGATGGTGCTGGGCGGGATGCTGATCGCCCTGCGCAGCCGCAACCAGTTCGGGCGCCTGCTGGGGCTGGGGATCGCG
ACCAATTTCTTCCTCTATTGCGCGGTCAACCTGTCGATGGTGATGGGGACGATTCCGGTCGGCGGCGTGCCGCTGCCGCT
GATTTCGTACGGCGGTTCGGCCATGCTGACGGTGATGTTCGGGTTCGGGCTGCTGCTGTCGGCCTGGGTGCACCGCAATT
CCACGTTCGGCGAGACCGCGTCGGACCCGTCATGA

Upstream 100 bases:

>100_bases
GACCCGCGACCCGGCGAACCGCAAGGAACCGCCGGGCCAGGTGGTGGCCGACATCGAATAGTCGCCGGTGGGCTGCGTTA
CCCCTGCCGGAGAGGGACAC

Downstream 100 bases:

>100_bases
CCGGCCTGCGACCGGTCGATCCCGCCACCGCACGGGCCTATCGGCTCAGCCTGTATCGCGCGGGCGGACAGTCGGTCCGC
ACCGGCCGCCGGCCGGTCCC

Product: rod shape-determining protein merD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MNFQKRLLRAEPNFRILAKLWQVNWLYVLLICVLAGVGYGALYSAAGGSSRPFAGPQTIRFAFGMVMMICVALTSPRVLV
RLAWPLYGLSLLLLVAVLRMGHVGKGAERWLIIGGMQVQPSELAKIALVLVLATWFHRISYRRMVNPLYLLPPALMVLLP
VGLVLKEPNLGTAVIIGVVGATIFFAAGMRLWQIVLLLAPLPLLGKFAYAHLHDYQKARITTFLHPESDPLGAGYNIIQS
KIALGSGGMWGQGYLHGTQGQLNFLPEKQTDFIFTMIAEEWGYVGGIVVIGLLMLMVLGGMLIALRSRNQFGRLLGLGIA
TNFFLYCAVNLSMVMGTIPVGGVPLPLISYGGSAMLTVMFGFGLLLSAWVHRNSTFGETASDPS

Sequences:

>Translated_384_residues
MNFQKRLLRAEPNFRILAKLWQVNWLYVLLICVLAGVGYGALYSAAGGSSRPFAGPQTIRFAFGMVMMICVALTSPRVLV
RLAWPLYGLSLLLLVAVLRMGHVGKGAERWLIIGGMQVQPSELAKIALVLVLATWFHRISYRRMVNPLYLLPPALMVLLP
VGLVLKEPNLGTAVIIGVVGATIFFAAGMRLWQIVLLLAPLPLLGKFAYAHLHDYQKARITTFLHPESDPLGAGYNIIQS
KIALGSGGMWGQGYLHGTQGQLNFLPEKQTDFIFTMIAEEWGYVGGIVVIGLLMLMVLGGMLIALRSRNQFGRLLGLGIA
TNFFLYCAVNLSMVMGTIPVGGVPLPLISYGGSAMLTVMFGFGLLLSAWVHRNSTFGETASDPS
>Mature_384_residues
MNFQKRLLRAEPNFRILAKLWQVNWLYVLLICVLAGVGYGALYSAAGGSSRPFAGPQTIRFAFGMVMMICVALTSPRVLV
RLAWPLYGLSLLLLVAVLRMGHVGKGAERWLIIGGMQVQPSELAKIALVLVLATWFHRISYRRMVNPLYLLPPALMVLLP
VGLVLKEPNLGTAVIIGVVGATIFFAAGMRLWQIVLLLAPLPLLGKFAYAHLHDYQKARITTFLHPESDPLGAGYNIIQS
KIALGSGGMWGQGYLHGTQGQLNFLPEKQTDFIFTMIAEEWGYVGGIVVIGLLMLMVLGGMLIALRSRNQFGRLLGLGIA
TNFFLYCAVNLSMVMGTIPVGGVPLPLISYGGSAMLTVMFGFGLLLSAWVHRNSTFGETASDPS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=327, Percent_Identity=44.0366972477064, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1786277, Length=273, Percent_Identity=36.6300366300366, Blast_Score=156, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41821; Mature: 41821

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQKRLLRAEPNFRILAKLWQVNWLYVLLICVLAGVGYGALYSAAGGSSRPFAGPQTIR
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHH
FAFGMVMMICVALTSPRVLVRLAWPLYGLSLLLLVAVLRMGHVGKGAERWLIIGGMQVQP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCEECH
SELAKIALVLVLATWFHRISYRRMVNPLYLLPPALMVLLPVGLVLKEPNLGTAVIIGVVG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHH
ATIFFAAGMRLWQIVLLLAPLPLLGKFAYAHLHDYQKARITTFLHPESDPLGAGYNIIQS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHH
KIALGSGGMWGQGYLHGTQGQLNFLPEKQTDFIFTMIAEEWGYVGGIVVIGLLMLMVLGG
HHHCCCCCCCCCCCEECCCCCEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
MLIALRSRNQFGRLLGLGIATNFFLYCAVNLSMVMGTIPVGGVPLPLISYGGSAMLTVMF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHH
GFGLLLSAWVHRNSTFGETASDPS
HHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNFQKRLLRAEPNFRILAKLWQVNWLYVLLICVLAGVGYGALYSAAGGSSRPFAGPQTIR
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHH
FAFGMVMMICVALTSPRVLVRLAWPLYGLSLLLLVAVLRMGHVGKGAERWLIIGGMQVQP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCEECH
SELAKIALVLVLATWFHRISYRRMVNPLYLLPPALMVLLPVGLVLKEPNLGTAVIIGVVG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHH
ATIFFAAGMRLWQIVLLLAPLPLLGKFAYAHLHDYQKARITTFLHPESDPLGAGYNIIQS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHH
KIALGSGGMWGQGYLHGTQGQLNFLPEKQTDFIFTMIAEEWGYVGGIVVIGLLMLMVLGG
HHHCCCCCCCCCCCEECCCCCEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
MLIALRSRNQFGRLLGLGIATNFFLYCAVNLSMVMGTIPVGGVPLPLISYGGSAMLTVMF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHH
GFGLLLSAWVHRNSTFGETASDPS
HHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]