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The map label for this gene is gap [H]

Identifier: 162148085

GI number: 162148085

Start: 2365002

End: 2366024

Strand: Direct

Name: gap [H]

Synonym: GDI_2302

Alternate gene names: 162148085

Gene position: 2365002-2366024 (Clockwise)

Preceding gene: 162148084

Following gene: 162148086

Centisome position: 59.96

GC content: 66.47

Gene sequence:

>1023_bases
ATGGCTGTCAAAGTCGCAATCAACGGTTTCGGCCGCATCGGCCGCCTCGTCCTGCGCGGCATCATCGAAAGCGGACGCAC
CGACGTGGTGCCGGTGGCCATCAACGACCTCGGCAGCGTCGCGGACAACGCCCACCTGCTGAGCTATGACAGCATCCATG
GCCGCTTCCCCGCCGACGTGCGGGTCGAGGGCAATGCGATCGTCATCACCGCCAACGGTCGCACCTATGCGCCGATCGCG
GTCTCGGCCGAGGCCGACCCGACCAAGGTGCCGTTCGACGGCGTGGACGTCGCGCTGGAATGCACCGGCCGCTTCACGAC
CAAGGAAAAGGCGGCGCACCTGATCGAGGCCGGCGCGCGCAAGGTCATCATCTCGGCCCCCGGAACGCATGTCGACGCCA
CCATCGTCTATGGCGTGAACCAGGATACGCTGACCAGCGACATGACGGTGATCTCCAACGCCTCGTGCACCACCAACTGC
CTGGCGCCCATCGCCAAGGTGCTGGACGAGACGTTCGGCATCGAGCGCGGCTACATGGTCACCATCCATTCCTATACCGG
CGACCAGCGCACGGTGGACACGCTGCACAAGGACCCGCGCCGGGCCCGCGCGGCGGCGATGAACATCATCCCGACCTCGA
CCGGCGCCGCGCGCGCGGTCGGTCTGGTGCTGCCGCACCTGAAGGGCAAGCTGGACGGCACCGCCATCCGCGTGCCCACG
CCCAACGTGTCGCTCGTCTCGCTCGATTTCGTGCCGACCCGCATCCCGGCCTCGGTCGAAGAGGTGAACGCGGCGATGCT
GAAGGCCGCGTCCGAAGGCCCGCTGAAGGGGATCCTGGCGTACAACACCGCGCCGCTGGTCAGCTCGGACTTCAACCACA
GCATCGCATCCTCGACCTTCGACGCGACCGAGACCGCGCTGGTCGATGGCGGCAAGCTGGTCCGGGTGTGCAGCTGGTAC
GACAATGAATGGGGCTTTTCCAACCGCATGTCCGATACCGCAGCGCTGTTCGGATCTCTGTGA

Upstream 100 bases:

>100_bases
GGCAGAAAGCGGAAGGTGGCCGCGGACGATACGCCGCCGGAGGCACCGTCCAGCTACGGCCGACATTCCGTAACGGCTGA
ATACTCGGGAGAGCAATAGA

Downstream 100 bases:

>100_bases
TGGCGGCGCTGTCTTTCAAGACGCTGGATGCGCTCCAGCCCAAAGGACGCAAGGTCCTGCTGCGCGCGGACCTGAACGTG
CCCGTCCGCGACGGGAAGAT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MAVKVAINGFGRIGRLVLRGIIESGRTDVVPVAINDLGSVADNAHLLSYDSIHGRFPADVRVEGNAIVITANGRTYAPIA
VSAEADPTKVPFDGVDVALECTGRFTTKEKAAHLIEAGARKVIISAPGTHVDATIVYGVNQDTLTSDMTVISNASCTTNC
LAPIAKVLDETFGIERGYMVTIHSYTGDQRTVDTLHKDPRRARAAAMNIIPTSTGAARAVGLVLPHLKGKLDGTAIRVPT
PNVSLVSLDFVPTRIPASVEEVNAAMLKAASEGPLKGILAYNTAPLVSSDFNHSIASSTFDATETALVDGGKLVRVCSWY
DNEWGFSNRMSDTAALFGSL

Sequences:

>Translated_340_residues
MAVKVAINGFGRIGRLVLRGIIESGRTDVVPVAINDLGSVADNAHLLSYDSIHGRFPADVRVEGNAIVITANGRTYAPIA
VSAEADPTKVPFDGVDVALECTGRFTTKEKAAHLIEAGARKVIISAPGTHVDATIVYGVNQDTLTSDMTVISNASCTTNC
LAPIAKVLDETFGIERGYMVTIHSYTGDQRTVDTLHKDPRRARAAAMNIIPTSTGAARAVGLVLPHLKGKLDGTAIRVPT
PNVSLVSLDFVPTRIPASVEEVNAAMLKAASEGPLKGILAYNTAPLVSSDFNHSIASSTFDATETALVDGGKLVRVCSWY
DNEWGFSNRMSDTAALFGSL
>Mature_339_residues
AVKVAINGFGRIGRLVLRGIIESGRTDVVPVAINDLGSVADNAHLLSYDSIHGRFPADVRVEGNAIVITANGRTYAPIAV
SAEADPTKVPFDGVDVALECTGRFTTKEKAAHLIEAGARKVIISAPGTHVDATIVYGVNQDTLTSDMTVISNASCTTNCL
APIAKVLDETFGIERGYMVTIHSYTGDQRTVDTLHKDPRRARAAAMNIIPTSTGAARAVGLVLPHLKGKLDGTAIRVPTP
NVSLVSLDFVPTRIPASVEEVNAAMLKAASEGPLKGILAYNTAPLVSSDFNHSIASSTFDATETALVDGGKLVRVCSWYD
NEWGFSNRMSDTAALFGSL

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=343, Percent_Identity=48.6880466472303, Blast_Score=281, Evalue=7e-76,
Organism=Homo sapiens, GI7657116, Length=334, Percent_Identity=45.2095808383234, Blast_Score=242, Evalue=3e-64,
Organism=Escherichia coli, GI1789295, Length=337, Percent_Identity=45.6973293768546, Blast_Score=288, Evalue=3e-79,
Organism=Escherichia coli, GI1788079, Length=339, Percent_Identity=48.9675516224189, Blast_Score=284, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=47.4474474474475, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=47.1471471471471, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI32566163, Length=333, Percent_Identity=47.1471471471471, Blast_Score=268, Evalue=4e-72,
Organism=Caenorhabditis elegans, GI17568413, Length=333, Percent_Identity=47.1471471471471, Blast_Score=267, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6321631, Length=334, Percent_Identity=47.9041916167665, Blast_Score=273, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=47.3053892215569, Blast_Score=272, Evalue=5e-74,
Organism=Saccharomyces cerevisiae, GI6322409, Length=334, Percent_Identity=47.0059880239521, Blast_Score=271, Evalue=2e-73,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=48.3483483483483, Blast_Score=265, Evalue=2e-71,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=48.3483483483483, Blast_Score=265, Evalue=2e-71,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=48.948948948949, Blast_Score=265, Evalue=3e-71,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=48.948948948949, Blast_Score=265, Evalue=3e-71,
Organism=Drosophila melanogaster, GI19922412, Length=333, Percent_Identity=44.7447447447448, Blast_Score=241, Evalue=7e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35889; Mature: 35758

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKVAINGFGRIGRLVLRGIIESGRTDVVPVAINDLGSVADNAHLLSYDSIHGRFPADV
CEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCE
RVEGNAIVITANGRTYAPIAVSAEADPTKVPFDGVDVALECTGRFTTKEKAAHLIEAGAR
EEECCEEEEEECCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCC
KVIISAPGTHVDATIVYGVNQDTLTSDMTVISNASCTTNCLAPIAKVLDETFGIERGYMV
EEEEECCCCCEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEE
TIHSYTGDQRTVDTLHKDPRRARAAAMNIIPTSTGAARAVGLVLPHLKGKLDGTAIRVPT
EEEECCCCCHHHHHHHCCHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECC
PNVSLVSLDFVPTRIPASVEEVNAAMLKAASEGPLKGILAYNTAPLVSSDFNHSIASSTF
CCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHCCCC
DATETALVDGGKLVRVCSWYDNEWGFSNRMSDTAALFGSL
CCCCEEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
AVKVAINGFGRIGRLVLRGIIESGRTDVVPVAINDLGSVADNAHLLSYDSIHGRFPADV
EEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCE
RVEGNAIVITANGRTYAPIAVSAEADPTKVPFDGVDVALECTGRFTTKEKAAHLIEAGAR
EEECCEEEEEECCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCC
KVIISAPGTHVDATIVYGVNQDTLTSDMTVISNASCTTNCLAPIAKVLDETFGIERGYMV
EEEEECCCCCEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEE
TIHSYTGDQRTVDTLHKDPRRARAAAMNIIPTSTGAARAVGLVLPHLKGKLDGTAIRVPT
EEEECCCCCHHHHHHHCCHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECC
PNVSLVSLDFVPTRIPASVEEVNAAMLKAASEGPLKGILAYNTAPLVSSDFNHSIASSTF
CCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHCCCC
DATETALVDGGKLVRVCSWYDNEWGFSNRMSDTAALFGSL
CCCCEEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]