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The map label for this gene is yicO [C]

Identifier: 162148022

GI number: 162148022

Start: 2294069

End: 2295445

Strand: Reverse

Name: yicO [C]

Synonym: GDI_2238

Alternate gene names: 162148022

Gene position: 2295445-2294069 (Counterclockwise)

Preceding gene: 162148024

Following gene: 162148021

Centisome position: 58.2

GC content: 68.85

Gene sequence:

>1377_bases
TTGAGGCATGACGGCGCCGGGGTGCGCGGGTGGATCGACCGCACCTTTCACGTGACCCGCCGGGGTTCGACCCTGGCGCG
GGAACTGGTCGCCGGGCTGACCACGTTCGGGGCCATGGCCTATATCATGATCGTCAATCCCGCGATCATGGCGCTGGCCG
GTTTGGACCGGCACGACATGATCATGACCACCATCGCCGCGTCGGTCTGCGGGTCCCTGCTGATGGCGCTGATGGCCAAC
CTGCCGATCGCGCTGGCCCCGGCCATGAGCAGCAACCTCGTCTTCGCCCAGGTCGTGGTGGTGCAGATGGGCGTCAAACC
GTCCGTCGCCTTCACGATGGTGCTGATCGGCGGCCTGGCCTTCGTCGCGCTGTCGCTGACACGGTGGCGGCAGAGGATCG
TCATGGGCTTCCCCATTCCGGTGCGCAACGGAATCCACTGCGCCATCGGGGCCTTCATCGCGCATATCGGCATGGTCAGC
GGGGGGCTGGCGGTCGGGGGCGCGCAGGGATTTTCCTTCGGCTCGCTGCACGATCCGGCGGTCCTGCTGGGACTCGCCGG
CCTGTTCCTGGCGGCTACCCTCCAGATGCTGCGGGTGCCCGCCGGCATGCTGCTGTCCATCGTCGCGGTGACCGTCGCCG
GCTGCTTCGTCCGCCATCCTGGCGGCCACCCGGTCACGACCCTGCCGGCGGCCTGGCTGGAATGGCCGCATTATCCCACC
AACATGCTGTTCCCGTTCGATTTCCACGGCTTCCTGTCGCATATCGGCATCGTCCTGCCGGTCACGATCTATTTCTTCCT
GGGCGACTTTTTCGATGCCACGGGCACCATGATGGCGGTGACGCGCCGCGCCGGCCTGACGGTCGAGGACGGGCAGCCGC
TGCTGGGCCGCGCGGCCTTCGCCGCGGACGGCACGGCCAGCGTGATCGGATCGGTGCTGGGGACATCGACCGTCTCGGCC
TATCTGGAATCGCTGGTCGGGGCCGAGGCCGGGGGGCGTACCGGGCTGGTCGGCGTCACGGTCGCCCTGCTGTTCCTGCT
GTCATCCGTGCTGTGGCCCGTCATCACCGCCGTGCCGGCGGTGGCGACCGCGCCGGTGCTGGTGCTGGTGGGCCTGGGTA
TGCTGTCGGACATGGGCCGATCGGGGGCCCAGTCCGGGGATGGCGACGTGGGCGGGGTCCTGGCGCCGCTGCTGATGGTG
CTGGTCACGGTCATGACCGGCAATTTCATGGTCAGCCTGGCGCTGGGGCTGCTGCTGTATACCGTGCTGGCGGTGGCGGG
GCGGCGCTGGGCCGAGGTCACGCCGATCCTGCTGGCACTGGACGCGGTGTTCGTCGTCTATCTGGTGCTGGCCAGCGGCA
TGGGGGGCGGATCGTGA

Upstream 100 bases:

>100_bases
CCCTGTCGACCACCCTTGCATCATATCGGAACCGGTAGGACATTCGCCCGCCGGTGGCGTCCGATCCGTGCCGCCCCGAT
ACGGAAGAGGAATCGAGGCT

Downstream 100 bases:

>100_bases
CGCGGCGCGTGAAAGGGATCATGGGACTGGGGGTAGGGGCATGGGTTGCCGCGAGCCTGGTCGCGGCGCCCGCCCGGGCC
GATGGCGGCGGGGCGTCCTG

Product: permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MRHDGAGVRGWIDRTFHVTRRGSTLARELVAGLTTFGAMAYIMIVNPAIMALAGLDRHDMIMTTIAASVCGSLLMALMAN
LPIALAPAMSSNLVFAQVVVVQMGVKPSVAFTMVLIGGLAFVALSLTRWRQRIVMGFPIPVRNGIHCAIGAFIAHIGMVS
GGLAVGGAQGFSFGSLHDPAVLLGLAGLFLAATLQMLRVPAGMLLSIVAVTVAGCFVRHPGGHPVTTLPAAWLEWPHYPT
NMLFPFDFHGFLSHIGIVLPVTIYFFLGDFFDATGTMMAVTRRAGLTVEDGQPLLGRAAFAADGTASVIGSVLGTSTVSA
YLESLVGAEAGGRTGLVGVTVALLFLLSSVLWPVITAVPAVATAPVLVLVGLGMLSDMGRSGAQSGDGDVGGVLAPLLMV
LVTVMTGNFMVSLALGLLLYTVLAVAGRRWAEVTPILLALDAVFVVYLVLASGMGGGS

Sequences:

>Translated_458_residues
MRHDGAGVRGWIDRTFHVTRRGSTLARELVAGLTTFGAMAYIMIVNPAIMALAGLDRHDMIMTTIAASVCGSLLMALMAN
LPIALAPAMSSNLVFAQVVVVQMGVKPSVAFTMVLIGGLAFVALSLTRWRQRIVMGFPIPVRNGIHCAIGAFIAHIGMVS
GGLAVGGAQGFSFGSLHDPAVLLGLAGLFLAATLQMLRVPAGMLLSIVAVTVAGCFVRHPGGHPVTTLPAAWLEWPHYPT
NMLFPFDFHGFLSHIGIVLPVTIYFFLGDFFDATGTMMAVTRRAGLTVEDGQPLLGRAAFAADGTASVIGSVLGTSTVSA
YLESLVGAEAGGRTGLVGVTVALLFLLSSVLWPVITAVPAVATAPVLVLVGLGMLSDMGRSGAQSGDGDVGGVLAPLLMV
LVTVMTGNFMVSLALGLLLYTVLAVAGRRWAEVTPILLALDAVFVVYLVLASGMGGGS
>Mature_458_residues
MRHDGAGVRGWIDRTFHVTRRGSTLARELVAGLTTFGAMAYIMIVNPAIMALAGLDRHDMIMTTIAASVCGSLLMALMAN
LPIALAPAMSSNLVFAQVVVVQMGVKPSVAFTMVLIGGLAFVALSLTRWRQRIVMGFPIPVRNGIHCAIGAFIAHIGMVS
GGLAVGGAQGFSFGSLHDPAVLLGLAGLFLAATLQMLRVPAGMLLSIVAVTVAGCFVRHPGGHPVTTLPAAWLEWPHYPT
NMLFPFDFHGFLSHIGIVLPVTIYFFLGDFFDATGTMMAVTRRAGLTVEDGQPLLGRAAFAADGTASVIGSVLGTSTVSA
YLESLVGAEAGGRTGLVGVTVALLFLLSSVLWPVITAVPAVATAPVLVLVGLGMLSDMGRSGAQSGDGDVGGVLAPLLMV
LVTVMTGNFMVSLALGLLLYTVLAVAGRRWAEVTPILLALDAVFVVYLVLASGMGGGS

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=458, Percent_Identity=32.7510917030568, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1790150, Length=445, Percent_Identity=34.3820224719101, Blast_Score=198, Evalue=7e-52,
Organism=Escherichia coli, GI1790499, Length=439, Percent_Identity=32.1184510250569, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI48994909, Length=435, Percent_Identity=32.183908045977, Blast_Score=164, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47367; Mature: 47367

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]