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The map label for this gene is 162148024

Identifier: 162148024

GI number: 162148024

Start: 2297250

End: 2298383

Strand: Reverse

Name: 162148024

Synonym: GDI_2240

Alternate gene names: NA

Gene position: 2298383-2297250 (Counterclockwise)

Preceding gene: 162148025

Following gene: 162148022

Centisome position: 58.27

GC content: 68.34

Gene sequence:

>1134_bases
ATGACATGGTCGATCCCCCTGGGGCGCATCGCGGGCACCGCAATCCGCGTGCATGTGACGTTCTTCCTGCTGTTGCTGTG
GATCGCGATGGTCGCCGGTGCCCAGGGCGGCCCTGCGGCGGCGTGGCAGGGCGTGGTGTTCATCATGCTGGTCTTCGTCT
GCGTGGTCCTGCATGAATTCGGACACATCCTGATGGCACGCCGTTTCGGCGTGACGACATCCGACATCACCCTGCTGCCG
ATCGGCGGCGTCGCGCGCCTGTCGCGCATGCCCGAACGGGCGGGGCAGGAATTGCTGGTGGCGCTGGCGGGGCCGGCGGT
CAATCTGGTCATCGGCCTGCTTCTGTTCGCCGCGACGGGAACGTGGCCCAGCCTGGATGCCGCGACGAGCGGGATGGTGG
GCGGCGGCGGGATGGTCGTCCGTCTGGCCTCGGTCAATCTGTTCCTGCTGCTGTTCAACCTGCTGCCGGCCTTTCCCATG
GATGGGGGGCGGGTGCTGCGCGCGCTTCTGGGCTATCGGATGGGTTTCGTGCGGGCGACGCAGGTCGCGGCCTCGGTGGG
GCAGGGGTTTGCGTTCCTGCTGGGCTTCCTGGGGCTGATCGGCAATCCGATCCTGCTGTTCATCGCCCTGTTCGTCTATC
TGGGCGCCGCGTCGGAGGCCCATATGGTGCAGTTGCGCCAGGTGGCGCAGGGGATGATCGCGGCGGATGCCATGATGACC
CGGTACGAGACGCTGCCGATGCTCACGACGCTGGACGAGGCGGTACGGGCCGCGATCCGCTGCGCACAGACGCTGTTTCC
CGTCATGGACGGGCAGGGCAGGCTACAGGGCGTGCTGACGCAGGCGGCCTTGATCAACCATCTGCAAATAGACGGGCCCG
GCGCGGTGGTGGCCGATGCCATGACGCCGGCCATCCCCGCCATCCATCCCTACCAGCCGCTGTCGGAGGCACTGCGCCTG
TTGCAGGAGGGCAACCTGCCGGCCGTCGCGGTGGTCGACGCCGGCGACCGCCTGGTCGGCCTGATCACGTCCGAGACGAT
CGGCGAACTGATGTTGACTCACGGGATACGCGTAACGCAGGGGCGGCGCGCGGCCGATTCCGATCGCCCCCCGACCGACC
GGGCCGCCGCCTAG

Upstream 100 bases:

>100_bases
GCCTGCCGCCTGATCGTCGCCGCCGGGAACCAAACCGGCAGGGCCGCGGCGCGTTGTGGATGCAGCCCCCTGCGGGGCTC
CAGCCCAGCGGAGGGCAAGC

Downstream 100 bases:

>100_bases
GTCTGGTGAATCCGGTTACGGCCTCAGCCGGATCAGGACGCACCCTCCAGGCTCGGGGCGGGCGTATGGTGCGGCGCGTC
GGCGACCTCGATCCGGTTGC

Product: peptidase protein

Products: NA

Alternate protein names: Site-2-type intermembrane protease [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MTWSIPLGRIAGTAIRVHVTFFLLLLWIAMVAGAQGGPAAAWQGVVFIMLVFVCVVLHEFGHILMARRFGVTTSDITLLP
IGGVARLSRMPERAGQELLVALAGPAVNLVIGLLLFAATGTWPSLDAATSGMVGGGGMVVRLASVNLFLLLFNLLPAFPM
DGGRVLRALLGYRMGFVRATQVAASVGQGFAFLLGFLGLIGNPILLFIALFVYLGAASEAHMVQLRQVAQGMIAADAMMT
RYETLPMLTTLDEAVRAAIRCAQTLFPVMDGQGRLQGVLTQAALINHLQIDGPGAVVADAMTPAIPAIHPYQPLSEALRL
LQEGNLPAVAVVDAGDRLVGLITSETIGELMLTHGIRVTQGRRAADSDRPPTDRAAA

Sequences:

>Translated_377_residues
MTWSIPLGRIAGTAIRVHVTFFLLLLWIAMVAGAQGGPAAAWQGVVFIMLVFVCVVLHEFGHILMARRFGVTTSDITLLP
IGGVARLSRMPERAGQELLVALAGPAVNLVIGLLLFAATGTWPSLDAATSGMVGGGGMVVRLASVNLFLLLFNLLPAFPM
DGGRVLRALLGYRMGFVRATQVAASVGQGFAFLLGFLGLIGNPILLFIALFVYLGAASEAHMVQLRQVAQGMIAADAMMT
RYETLPMLTTLDEAVRAAIRCAQTLFPVMDGQGRLQGVLTQAALINHLQIDGPGAVVADAMTPAIPAIHPYQPLSEALRL
LQEGNLPAVAVVDAGDRLVGLITSETIGELMLTHGIRVTQGRRAADSDRPPTDRAAA
>Mature_376_residues
TWSIPLGRIAGTAIRVHVTFFLLLLWIAMVAGAQGGPAAAWQGVVFIMLVFVCVVLHEFGHILMARRFGVTTSDITLLPI
GGVARLSRMPERAGQELLVALAGPAVNLVIGLLLFAATGTWPSLDAATSGMVGGGGMVVRLASVNLFLLLFNLLPAFPMD
GGRVLRALLGYRMGFVRATQVAASVGQGFAFLLGFLGLIGNPILLFIALFVYLGAASEAHMVQLRQVAQGMIAADAMMTR
YETLPMLTTLDEAVRAAIRCAQTLFPVMDGQGRLQGVLTQAALINHLQIDGPGAVVADAMTPAIPAIHPYQPLSEALRLL
QEGNLPAVAVVDAGDRLVGLITSETIGELMLTHGIRVTQGRRAADSDRPPTDRAAA

Specific function: Unknown

COG id: COG1994

COG function: function code R; Zn-dependent proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR008915
- InterPro:   IPR016483 [H]

Pfam domain/function: PF00571 CBS; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 39789; Mature: 39658

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWSIPLGRIAGTAIRVHVTFFLLLLWIAMVAGAQGGPAAAWQGVVFIMLVFVCVVLHEF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GHILMARRFGVTTSDITLLPIGGVARLSRMPERAGQELLVALAGPAVNLVIGLLLFAATG
HHHHHHHHCCCCCCCEEEEECCHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
TWPSLDAATSGMVGGGGMVVRLASVNLFLLLFNLLPAFPMDGGRVLRALLGYRMGFVRAT
CCCCCHHHHCCCCCCCHHEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
QVAASVGQGFAFLLGFLGLIGNPILLFIALFVYLGAASEAHMVQLRQVAQGMIAADAMMT
HHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RYETLPMLTTLDEAVRAAIRCAQTLFPVMDGQGRLQGVLTQAALINHLQIDGPGAVVADA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCHHHHH
MTPAIPAIHPYQPLSEALRLLQEGNLPAVAVVDAGDRLVGLITSETIGELMLTHGIRVTQ
HCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHCCCEECC
GRRAADSDRPPTDRAAA
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TWSIPLGRIAGTAIRVHVTFFLLLLWIAMVAGAQGGPAAAWQGVVFIMLVFVCVVLHEF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GHILMARRFGVTTSDITLLPIGGVARLSRMPERAGQELLVALAGPAVNLVIGLLLFAATG
HHHHHHHHCCCCCCCEEEEECCHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
TWPSLDAATSGMVGGGGMVVRLASVNLFLLLFNLLPAFPMDGGRVLRALLGYRMGFVRAT
CCCCCHHHHCCCCCCCHHEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
QVAASVGQGFAFLLGFLGLIGNPILLFIALFVYLGAASEAHMVQLRQVAQGMIAADAMMT
HHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RYETLPMLTTLDEAVRAAIRCAQTLFPVMDGQGRLQGVLTQAALINHLQIDGPGAVVADA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCHHHHH
MTPAIPAIHPYQPLSEALRLLQEGNLPAVAVVDAGDRLVGLITSETIGELMLTHGIRVTQ
HCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHCCCEECC
GRRAADSDRPPTDRAAA
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]