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The map label for this gene is mtnA [H]

Identifier: 162148017

GI number: 162148017

Start: 2288985

End: 2290082

Strand: Reverse

Name: mtnA [H]

Synonym: GDI_2233

Alternate gene names: 162148017

Gene position: 2290082-2288985 (Counterclockwise)

Preceding gene: 162148018

Following gene: 162148016

Centisome position: 58.06

GC content: 70.77

Gene sequence:

>1098_bases
ATGAAAATCGGCACCGTACCTTATCGCAGCGTGTGGGTGGACCAGGATGACGGCTGGTCGGTCCATATCTTCGACCAGAC
CCGTTTGCCGTGGGAACTGGACATCCTGCGCCTGACCGAACGGGACCAGGTGGCGCACGCGATCCGCACCATGCAGGTGC
GCGGCGCGCCGCTGATCGGCGCGGTCGCGGCCTATGGGCTGGCGCTGGCGCTGCGCGTCGATGCCGGCGACGCGGCGATG
GAACGCGACGCCGCCCTGCTGGCCGCCACCCGCCCGACCGCGATCAACCTGCGCTGGGCCATCGAGAGGATGCTGGGCCG
GCTGCGGCCGCTGCCGGCCGCCGAACGCGTCGCCGCCGCGTATGACGAGGCCGGGCGCATCTGCGACGAGGACGCGGCCC
AGAACGAAGCCATCGGCCGGCACGGCCTGCGCCTGATCCAGGACATCGTGGCGCGGCGCGGCGAGGGCACGACGGTCAAC
ATCCTGACGCATTGCAACGCCGGCTGGATCGCCACCGTCGACTGGGGCACCGCGCTGGCCCCGATCTACATGGCCCATGA
CAGCGGACTGAGCGTCCATGTGTGGGTGGACGAAACCCGCCCGCGCAACCAGGGCGCGGCGCTGACGGCATGGGAACTGG
GCAGCCACGGGGTGCCGCATACGGTGGTGGCCGACAATGCGGGCGGCCACCTGATGCAGCACGGCGCGGTGGACCTGGTG
ATCGTGGGCACCGACCGCGTCACGCGGACCGGCGACGTGGCGAACAAGATCGGGACCTACCTGAAGGCGCTGGCGGCGCA
TGACAACGGCGTGCCGTTCTGGGTCGCGCTGCCCTCCACGACGATCGACTGGCATGTCAGTGACGGGCTGACCGAAATCC
CGATCGAGGAACGCAACGGCGCCGAGGTCACCTCCATCACCGGCCGCACGGAAGACGGGCGCATCGAGACGGTGCGCCTG
ACCCCGCCGGACAGCCGCGCGGCCAACCCGGCCTTCGACGTGACGCCCGCGCGCCTGGTGACGGGCCTGATTACCGAGCG
CGGCTGCTGCCAGGCCACGCAGGCCGGCCTGGCGGGGCTGTTTCCCGAACACGCATGA

Upstream 100 bases:

>100_bases
GGGGCAACCCCGGCCTTGCTTTCTTGAAAGCCAATCCCAATTCAGCCTGATATAAGCCCGCGCGGCCTTCTCTTTCTCTC
ACTCAACGGAATCGCGCAGG

Downstream 100 bases:

>100_bases
CGCCACGCGGCCGGCCGACCCGTCTCGGCAACCCTTGACAGGGGCGGCCCGGCCCGGCTTCCTCCGCCTTCGATCGCGCG
GGGCGCATGGCGTCCCGTCC

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKIGTVPYRSVWVDQDDGWSVHIFDQTRLPWELDILRLTERDQVAHAIRTMQVRGAPLIGAVAAYGLALALRVDAGDAAM
ERDAALLAATRPTAINLRWAIERMLGRLRPLPAAERVAAAYDEAGRICDEDAAQNEAIGRHGLRLIQDIVARRGEGTTVN
ILTHCNAGWIATVDWGTALAPIYMAHDSGLSVHVWVDETRPRNQGAALTAWELGSHGVPHTVVADNAGGHLMQHGAVDLV
IVGTDRVTRTGDVANKIGTYLKALAAHDNGVPFWVALPSTTIDWHVSDGLTEIPIEERNGAEVTSITGRTEDGRIETVRL
TPPDSRAANPAFDVTPARLVTGLITERGCCQATQAGLAGLFPEHA

Sequences:

>Translated_365_residues
MKIGTVPYRSVWVDQDDGWSVHIFDQTRLPWELDILRLTERDQVAHAIRTMQVRGAPLIGAVAAYGLALALRVDAGDAAM
ERDAALLAATRPTAINLRWAIERMLGRLRPLPAAERVAAAYDEAGRICDEDAAQNEAIGRHGLRLIQDIVARRGEGTTVN
ILTHCNAGWIATVDWGTALAPIYMAHDSGLSVHVWVDETRPRNQGAALTAWELGSHGVPHTVVADNAGGHLMQHGAVDLV
IVGTDRVTRTGDVANKIGTYLKALAAHDNGVPFWVALPSTTIDWHVSDGLTEIPIEERNGAEVTSITGRTEDGRIETVRL
TPPDSRAANPAFDVTPARLVTGLITERGCCQATQAGLAGLFPEHA
>Mature_365_residues
MKIGTVPYRSVWVDQDDGWSVHIFDQTRLPWELDILRLTERDQVAHAIRTMQVRGAPLIGAVAAYGLALALRVDAGDAAM
ERDAALLAATRPTAINLRWAIERMLGRLRPLPAAERVAAAYDEAGRICDEDAAQNEAIGRHGLRLIQDIVARRGEGTTVN
ILTHCNAGWIATVDWGTALAPIYMAHDSGLSVHVWVDETRPRNQGAALTAWELGSHGVPHTVVADNAGGHLMQHGAVDLV
IVGTDRVTRTGDVANKIGTYLKALAAHDNGVPFWVALPSTTIDWHVSDGLTEIPIEERNGAEVTSITGRTEDGRIETVRL
TPPDSRAANPAFDVTPARLVTGLITERGCCQATQAGLAGLFPEHA

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=346, Percent_Identity=41.0404624277457, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI23943880, Length=154, Percent_Identity=47.4025974025974, Blast_Score=125, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17557462, Length=337, Percent_Identity=33.2344213649852, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17557123, Length=198, Percent_Identity=29.7979797979798, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325375, Length=398, Percent_Identity=30.9045226130653, Blast_Score=172, Evalue=7e-44,
Organism=Drosophila melanogaster, GI21357667, Length=351, Percent_Identity=37.6068376068376, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24651647, Length=351, Percent_Identity=37.6068376068376, Blast_Score=188, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 39337; Mature: 39337

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGTVPYRSVWVDQDDGWSVHIFDQTRLPWELDILRLTERDQVAHAIRTMQVRGAPLIG
CCCCCCCCCEEEEECCCCCEEEEEECCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCHHH
AVAAYGLALALRVDAGDAAMERDAALLAATRPTAINLRWAIERMLGRLRPLPAAERVAAA
HHHHCCEEEEEEECCCCHHHHCCCEEEEECCCCEEEHHHHHHHHHHHCCCCCHHHHHHHH
YDEAGRICDEDAAQNEAIGRHGLRLIQDIVARRGEGTTVNILTHCNAGWIATVDWGTALA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCE
PIYMAHDSGLSVHVWVDETRPRNQGAALTAWELGSHGVPHTVVADNAGGHLMQHGAVDLV
EEEEEECCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCEEECCCEEEE
IVGTDRVTRTGDVANKIGTYLKALAAHDNGVPFWVALPSTTIDWHVSDGLTEIPIEERNG
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCEECCCCCCCC
AEVTSITGRTEDGRIETVRLTPPDSRAANPAFDVTPARLVTGLITERGCCQATQAGLAGL
CEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCC
FPEHA
CCCCC
>Mature Secondary Structure
MKIGTVPYRSVWVDQDDGWSVHIFDQTRLPWELDILRLTERDQVAHAIRTMQVRGAPLIG
CCCCCCCCCEEEEECCCCCEEEEEECCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCHHH
AVAAYGLALALRVDAGDAAMERDAALLAATRPTAINLRWAIERMLGRLRPLPAAERVAAA
HHHHCCEEEEEEECCCCHHHHCCCEEEEECCCCEEEHHHHHHHHHHHCCCCCHHHHHHHH
YDEAGRICDEDAAQNEAIGRHGLRLIQDIVARRGEGTTVNILTHCNAGWIATVDWGTALA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCE
PIYMAHDSGLSVHVWVDETRPRNQGAALTAWELGSHGVPHTVVADNAGGHLMQHGAVDLV
EEEEEECCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCEEECCCEEEE
IVGTDRVTRTGDVANKIGTYLKALAAHDNGVPFWVALPSTTIDWHVSDGLTEIPIEERNG
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCEECCCCCCCC
AEVTSITGRTEDGRIETVRLTPPDSRAANPAFDVTPARLVTGLITERGCCQATQAGLAGL
CEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCC
FPEHA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA