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The map label for this gene is htpG [H]

Identifier: 162148018

GI number: 162148018

Start: 2290217

End: 2292127

Strand: Reverse

Name: htpG [H]

Synonym: GDI_2234

Alternate gene names: 162148018

Gene position: 2292127-2290217 (Counterclockwise)

Preceding gene: 162148019

Following gene: 162148017

Centisome position: 58.11

GC content: 68.97

Gene sequence:

>1911_bases
GTGGAACGGAGAGACACAAACATGACCGATCAGGCTACGGATTCGGACAAGGCCCAGCCCGCACCCCAGGCAGGGGGCGA
GGAACATGCGTTCAGTGCGGAGGTCGGGCGGCTGCTCGACCTGGTGGTCCACGCGCTGTATTCCGAGCGCGAGATCTTCC
TGCGCGAACTGGTGGCCAACGCCGCCGATGCCACGGACCGCCGCCGGTTCGAGGCCCTGACCGACGCCGCCCGGACCCTG
CCGGAAGGGGCCGGGGTGCGCATCGACCCCGACAAGGACGCCCGCCGCCTGACCATCAGCGATGACGGCACGGGCATGAG
CAAGGACGAACTGGCGCGCAACCTGGGCACCATCGCGCGCTCGGGCACCCGCGCCTTCGGCCAGGAACTGGACAAGCAGA
AGCCCGGGGAGAACGCCGGGGACCGTCCCAGCCTGATCGGGCAGTTCGGCGTCGGGTTCTATGCCGCCTTCATGGTCGCG
GACCATGTCGACGTGGTGTCGCGCCGCGCCGGTAGCGACGAGGCGTGGCGCTGGTCGTCGGACGGCAAGGGCAGCTTCAC
CCTCAGCCCCGCGACGCGTGAGCGCCCCGGCACCGACATCGTGCTGTATATCAAGGAAGATGCCGACGAATTCCTCGATG
CATGGCGCCTGGAATCGATCGTGCGCAAATGGGCCGATCACATCGCCTGGCCGATCACCATCCGCCGCGACGGCGAGGAC
ACGCCGGCCAATGCCGGAACCGCCCTTTGGCGCAAGCCCAAGGGCGAGGTGACCGAGGAGCAGCTCACCGAATTCTACCG
GCATGTCAGCCATAATTTCGATACGCCCTGGGCGACGCTGCACTGGCATGCCGAGGGCACGATCGAGTTCACCGCCCTGC
TGTTCATCCCCGGCAGCCGGCCCTTCGAATTCGGCGAGCAGGTGCGTGACAGCCGCGTGCGTCTGCATGTCCGGCGCATG
TTCATCACCGACGACGCGGCGCTGCTGCCGCCGTGGATGCGCTTCGTGCAGGGCGTGGTGGATACCGAGGACCTGCCGCT
GAACGTCTCGCGCGAGATGCTGCAGGCCACCCCGGTTCTGGCCCGCATCCGCAAGGCCGTGACCAATCGGGTGCTGAACG
AACTGCGCAGCCGGGCCACGGATGCGGAATCCTATGCGACGTTCTGGGACAATTTCGGCCCGGTGCTGAAGGAAGGGATC
TGGGACGACGCGGAATACCGCACCGACCTGGCGGGCCTGGCCCGGTTCCGTTCCAGCACGGAAGAAGGCTGGACGACCCT
GGCCGACTACGTGTCGCGCATGAAGGACGGGCAGGAGGCGATCTATTACCTGACCGGCGACAACCCCGACACGCTGCCGG
CCTCGCCGCAACTGGAAGGCTTCCGGGCGCGGGGGATCGAGGTCCTGCTGCTGTCCGATCCGGTCGATTCCTTCTGGCCG
GACCGGCTGGGCACGTTCGAGGGCAAGGCCCTGCGCAGCGTCAGCCAGGGTCACGCCGACCTGGACAAGTTCGAGGCCCC
GCAGGACGATGGGGCCCGGGCCGACCTGGAGGCGCTGCTGCCGGCCATGAAGGCCGCGCTGGGCGAGGCCGTGTCGGACG
TGCGCGGCACCAGCCGGCTGGTCGGCAGCGCGGTCGTGCTGTCGGCGGCGGGGCAGGGGCCGGACCTGCAACTGCAGCGC
CTGCTGCGCCGCAGCGGCCAGGCGGTGCCCGACCAGGCCCCGGTGCTGGAAATCAACGCGACCCATCCGCTGATCCGCGA
CCTGGCGGACCGGGTGGCGCGCGGCGAATCGGTGGCGGACATCGCGCTGATCCTGCTGGACATCGCGCGGATCCAGGACG
GCGAAAGCCCCAAGGACCCGACCGCCTTCGCCAGCCGCCTGACGGCGACGCTGACCCAAATCCAGGGCTGA

Upstream 100 bases:

>100_bases
GCCCACTTTGCCGACGGACTTCGAATGACGGGTATGCAGCGCGTCGCAGGTCATTGAAAACAGGCATTTCGTGACCCATA
TGACCGCCTAAATCGTTAGT

Downstream 100 bases:

>100_bases
GGCGTTCCTGGTTGGCAAGGTCGGGGCAAGGCCGGGGGCAACCCCGGCCTTGCTTTCTTGAAAGCCAATCCCAATTCAGC
CTGATATAAGCCCGCGCGGC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MERRDTNMTDQATDSDKAQPAPQAGGEEHAFSAEVGRLLDLVVHALYSEREIFLRELVANAADATDRRRFEALTDAARTL
PEGAGVRIDPDKDARRLTISDDGTGMSKDELARNLGTIARSGTRAFGQELDKQKPGENAGDRPSLIGQFGVGFYAAFMVA
DHVDVVSRRAGSDEAWRWSSDGKGSFTLSPATRERPGTDIVLYIKEDADEFLDAWRLESIVRKWADHIAWPITIRRDGED
TPANAGTALWRKPKGEVTEEQLTEFYRHVSHNFDTPWATLHWHAEGTIEFTALLFIPGSRPFEFGEQVRDSRVRLHVRRM
FITDDAALLPPWMRFVQGVVDTEDLPLNVSREMLQATPVLARIRKAVTNRVLNELRSRATDAESYATFWDNFGPVLKEGI
WDDAEYRTDLAGLARFRSSTEEGWTTLADYVSRMKDGQEAIYYLTGDNPDTLPASPQLEGFRARGIEVLLLSDPVDSFWP
DRLGTFEGKALRSVSQGHADLDKFEAPQDDGARADLEALLPAMKAALGEAVSDVRGTSRLVGSAVVLSAAGQGPDLQLQR
LLRRSGQAVPDQAPVLEINATHPLIRDLADRVARGESVADIALILLDIARIQDGESPKDPTAFASRLTATLTQIQG

Sequences:

>Translated_636_residues
MERRDTNMTDQATDSDKAQPAPQAGGEEHAFSAEVGRLLDLVVHALYSEREIFLRELVANAADATDRRRFEALTDAARTL
PEGAGVRIDPDKDARRLTISDDGTGMSKDELARNLGTIARSGTRAFGQELDKQKPGENAGDRPSLIGQFGVGFYAAFMVA
DHVDVVSRRAGSDEAWRWSSDGKGSFTLSPATRERPGTDIVLYIKEDADEFLDAWRLESIVRKWADHIAWPITIRRDGED
TPANAGTALWRKPKGEVTEEQLTEFYRHVSHNFDTPWATLHWHAEGTIEFTALLFIPGSRPFEFGEQVRDSRVRLHVRRM
FITDDAALLPPWMRFVQGVVDTEDLPLNVSREMLQATPVLARIRKAVTNRVLNELRSRATDAESYATFWDNFGPVLKEGI
WDDAEYRTDLAGLARFRSSTEEGWTTLADYVSRMKDGQEAIYYLTGDNPDTLPASPQLEGFRARGIEVLLLSDPVDSFWP
DRLGTFEGKALRSVSQGHADLDKFEAPQDDGARADLEALLPAMKAALGEAVSDVRGTSRLVGSAVVLSAAGQGPDLQLQR
LLRRSGQAVPDQAPVLEINATHPLIRDLADRVARGESVADIALILLDIARIQDGESPKDPTAFASRLTATLTQIQG
>Mature_636_residues
MERRDTNMTDQATDSDKAQPAPQAGGEEHAFSAEVGRLLDLVVHALYSEREIFLRELVANAADATDRRRFEALTDAARTL
PEGAGVRIDPDKDARRLTISDDGTGMSKDELARNLGTIARSGTRAFGQELDKQKPGENAGDRPSLIGQFGVGFYAAFMVA
DHVDVVSRRAGSDEAWRWSSDGKGSFTLSPATRERPGTDIVLYIKEDADEFLDAWRLESIVRKWADHIAWPITIRRDGED
TPANAGTALWRKPKGEVTEEQLTEFYRHVSHNFDTPWATLHWHAEGTIEFTALLFIPGSRPFEFGEQVRDSRVRLHVRRM
FITDDAALLPPWMRFVQGVVDTEDLPLNVSREMLQATPVLARIRKAVTNRVLNELRSRATDAESYATFWDNFGPVLKEGI
WDDAEYRTDLAGLARFRSSTEEGWTTLADYVSRMKDGQEAIYYLTGDNPDTLPASPQLEGFRARGIEVLLLSDPVDSFWP
DRLGTFEGKALRSVSQGHADLDKFEAPQDDGARADLEALLPAMKAALGEAVSDVRGTSRLVGSAVVLSAAGQGPDLQLQR
LLRRSGQAVPDQAPVLEINATHPLIRDLADRVARGESVADIALILLDIARIQDGESPKDPTAFASRLTATLTQIQG

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=633, Percent_Identity=34.2812006319115, Blast_Score=342, Evalue=9e-94,
Organism=Homo sapiens, GI154146191, Length=400, Percent_Identity=32.75, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI4507677, Length=404, Percent_Identity=34.6534653465347, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI20149594, Length=400, Percent_Identity=33.5, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI153792590, Length=400, Percent_Identity=32.75, Blast_Score=230, Evalue=3e-60,
Organism=Escherichia coli, GI1786679, Length=629, Percent_Identity=42.6073131955485, Blast_Score=473, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI17559162, Length=669, Percent_Identity=34.3796711509716, Blast_Score=403, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17542208, Length=673, Percent_Identity=33.8781575037147, Blast_Score=357, Evalue=2e-98,
Organism=Caenorhabditis elegans, GI115535205, Length=640, Percent_Identity=33.125, Blast_Score=313, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI115535167, Length=428, Percent_Identity=35.5140186915888, Blast_Score=253, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6325016, Length=411, Percent_Identity=33.3333333333333, Blast_Score=249, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6323840, Length=411, Percent_Identity=33.3333333333333, Blast_Score=248, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24586016, Length=596, Percent_Identity=35.738255033557, Blast_Score=351, Evalue=9e-97,
Organism=Drosophila melanogaster, GI21357739, Length=683, Percent_Identity=33.0893118594436, Blast_Score=348, Evalue=7e-96,
Organism=Drosophila melanogaster, GI17647529, Length=405, Percent_Identity=34.5679012345679, Blast_Score=258, Evalue=9e-69,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 70342; Mature: 70342

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERRDTNMTDQATDSDKAQPAPQAGGEEHAFSAEVGRLLDLVVHALYSEREIFLRELVAN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AADATDRRRFEALTDAARTLPEGAGVRIDPDKDARRLTISDDGTGMSKDELARNLGTIAR
HCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHH
SGTRAFGQELDKQKPGENAGDRPSLIGQFGVGFYAAFMVADHVDVVSRRAGSDEAWRWSS
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
DGKGSFTLSPATRERPGTDIVLYIKEDADEFLDAWRLESIVRKWADHIAWPITIRRDGED
CCCCCEEECCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
TPANAGTALWRKPKGEVTEEQLTEFYRHVSHNFDTPWATLHWHAEGTIEFTALLFIPGSR
CCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEECCCC
PFEFGEQVRDSRVRLHVRRMFITDDAALLPPWMRFVQGVVDTEDLPLNVSREMLQATPVL
CHHHHHHHHHHHHHHHHHHHEECCCCHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ARIRKAVTNRVLNELRSRATDAESYATFWDNFGPVLKEGIWDDAEYRTDLAGLARFRSST
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
EEGWTTLADYVSRMKDGQEAIYYLTGDNPDTLPASPQLEGFRARGIEVLLLSDPVDSFWP
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHCCCEEEEEEECCCHHHCC
DRLGTFEGKALRSVSQGHADLDKFEAPQDDGARADLEALLPAMKAALGEAVSDVRGTSRL
HHCCCCCCHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGSAVVLSAAGQGPDLQLQRLLRRSGQAVPDQAPVLEINATHPLIRDLADRVARGESVAD
HHHHHHEECCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHH
IALILLDIARIQDGESPKDPTAFASRLTATLTQIQG
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERRDTNMTDQATDSDKAQPAPQAGGEEHAFSAEVGRLLDLVVHALYSEREIFLRELVAN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AADATDRRRFEALTDAARTLPEGAGVRIDPDKDARRLTISDDGTGMSKDELARNLGTIAR
HCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHH
SGTRAFGQELDKQKPGENAGDRPSLIGQFGVGFYAAFMVADHVDVVSRRAGSDEAWRWSS
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
DGKGSFTLSPATRERPGTDIVLYIKEDADEFLDAWRLESIVRKWADHIAWPITIRRDGED
CCCCCEEECCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
TPANAGTALWRKPKGEVTEEQLTEFYRHVSHNFDTPWATLHWHAEGTIEFTALLFIPGSR
CCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEECCCC
PFEFGEQVRDSRVRLHVRRMFITDDAALLPPWMRFVQGVVDTEDLPLNVSREMLQATPVL
CHHHHHHHHHHHHHHHHHHHEECCCCHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ARIRKAVTNRVLNELRSRATDAESYATFWDNFGPVLKEGIWDDAEYRTDLAGLARFRSST
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
EEGWTTLADYVSRMKDGQEAIYYLTGDNPDTLPASPQLEGFRARGIEVLLLSDPVDSFWP
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHCCCEEEEEEECCCHHHCC
DRLGTFEGKALRSVSQGHADLDKFEAPQDDGARADLEALLPAMKAALGEAVSDVRGTSRL
HHCCCCCCHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGSAVVLSAAGQGPDLQLQRLLRRSGQAVPDQAPVLEINATHPLIRDLADRVARGESVAD
HHHHHHEECCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHH
IALILLDIARIQDGESPKDPTAFASRLTATLTQIQG
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA