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The map label for this gene is cysS [H]

Identifier: 162147983

GI number: 162147983

Start: 2251171

End: 2253306

Strand: Direct

Name: cysS [H]

Synonym: GDI_2199

Alternate gene names: 162147983

Gene position: 2251171-2253306 (Clockwise)

Preceding gene: 162147981

Following gene: 162147986

Centisome position: 57.08

GC content: 68.31

Gene sequence:

>2136_bases
ATGCCAGATTCCATGCCGCAACTGACCCTGCACGACAGCAGAAGCCGCAAGACGGTTCCGTTCGCGCCCCTCGATCCGGG
GAATGTGCGGGTCTATTATTGCGGGCCGACCGTCTATGACCTGGCCCATATCGGCAACCTGCGGGCGATGGTGACGGCCG
ATATCCTGGTCCGGCTGCTGCGGCACCTGTATCCGCGCGTGACCTATGTGCGCAACATCACGGACGTGGACGACAAGATC
AACACCCGCGCCCGCGCGAACGGCGAGACGATCGACAGCCTGACCGCCCGCACGATCCGGGATTTCCACGAGGACCTGGA
CGCCGTCGGCATCCTGCCCCCGGATATCGAACCCCGCGCCACCCACCACATCGCCGAGATGCTGACCCTGATCGGCCAGT
TGATCGACAGCGGCCATGCCTACGAGGCGCAGGGTCATGTCCTGTTCGCCGTCAGCCGCTTTCCAGCCTATGGCGCGCTG
TCGGGGCGCAGCCCCGAGGACCTGCTGGCCGGCGCACGGGTCGAAGTCGCGCCCTACAAGCGCGATCCGGGCGATTTCGT
GCTGTGGAAGCCGTCGGCGCCCGACCTGCCGGGCTGGGAGAGCCCGTGGGGCCGGGGCCGGCCGGGCTGGCATATCGAAT
GCTCGGCCATGTCGCATCGCTATCTGGGCGAGAGCTTCGACATTCATGGCGGCGGCAGCGACCTGCTGTTCCCGCACCAC
GAAAACGAACTGGCGCAAAGCCAGTGCTGCTTCCCGCACGGCCGCTTCGCCAACCACTGGGTGCATAACGCGATGCTGCT
GGTGAACGGCGAGAAGATGTCCAAGTCGCTGGGCAATTTCCTGACCGTCCGCGACGCACTAAGCGTCAGTCCGGCCGAGG
CGCTGCGCCTGCTGCTGCTGCACGCGCAGTACCGGTCGGTGCTGAACTTCACCCTGGCCGGGCTGGAGGACGCGAAGCAG
ACGCTGAACCGGTTCTATCGCGCCGTCGGCGACACGCCGCCCGACGGCACGGTTCCGGTCCCCGCCCCCGTGCTGGCCGC
CCTGTGCGACGACCTGAACACGCCCCGCGCGCTGGCGGAAATGCATGCCCTGGCTGACCGGGCCCTGGCGGGCGACCGCG
ACGCGGCGCTGGGCCTGCGCGCGGCGGGGCAGTTGCTGGGGCTGCTGGGACAGACGGAGGATGCGTGGTTCCGCGCGGGT
ACTTACGTCCATCCAGAGACGATCGAAAGGCTGATCGTCGAACGGCAGGATGCCCGCAAATCCCGCGATTTTTGCCCGCG
CCGACGCTATTCGCGAAAGTCTGGCGAAGGACGGCATCGTGCTGGAAGACGGGCCGTCCGGCACCACCTGGAGGCGCGCA
TGACCGGCCGCGACGGCGGGGCCGATATCGGCCCGATCGGCAACAGCCCGGTCGTCATCCTGGTGCGCCCGCAGATGGCC
GAGAATATCGGCACCACGGCGCGGGCCATGGCCAATGGCGGACTGTTCCACCTGCGCCTGGTCGCCCCGCGCGACGGCTG
GCCGCTGGAGCGCGCCTGGCGCTCGGCCTCGGGCGCCGACCGCATCCTGGAAGCCGCGACGGTGCATGACAGCGTCGATG
ACGCGATCGCCGACCTGCACCATGTCTTCGCGACCTGCCCGCGCCCGCGCCATATCGTCAAGACGGTGCTGACCGCACGC
GGGGGCGCCGCCGAACTGCGGCAGATGAGCGGGCGCGGACTGCGCACCGGCCTGCTGTTCGGCCCCGAGCGCGCCGGCCT
GGACAACGAGGACATGGCCCGGGCCGACGCCCTGATCCGCTATCCGCTGAACCCGGCCTTCATGTCGCTGAACCTGGCGC
AGGCGGTCATGATCATGGCCTACGAATGGTGGATGGCCGAAGACGCCACCCCGCCCCGCGCGCTGATGACCAATGAAACC
CATGTCGCCACCAAGGGCGAACTGGACAATTTCATGCGCCACCTGATCGACGATCTGGACGAATGCGGCTTCCTGCGCAA
CGAGCAGAAGCGCGCGGGCATGGTGCGCAACCTGCGCCATTTCTTCACCCGGGGCGAAGTCACGGAACAGGAACTGCGCA
CCCTGCACGGCGTGGTGACGGAACTGACCCGGGGGCGCCGGGCGCGCGGGCAATGA

Upstream 100 bases:

>100_bases
CCGCAAAGACCAGACGCGGCGGGACCATGCCCCCCTTTCGTCCCTGCCGCCGCACAAGGGTGTTGCGTCCGCCCCGCCGC
TGTCGCATCTAGGCCCCATC

Downstream 100 bases:

>100_bases
AGAGCGTCCTTCGGCAACAGGGCCGTTGCCACCTCGATTCGTCCCCGCGGATGCGGGGAACACGCATCCGCGTGCCCTGC
AACCCGTCCCAATCCATGCC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 711; Mature: 710

Protein sequence:

>711_residues
MPDSMPQLTLHDSRSRKTVPFAPLDPGNVRVYYCGPTVYDLAHIGNLRAMVTADILVRLLRHLYPRVTYVRNITDVDDKI
NTRARANGETIDSLTARTIRDFHEDLDAVGILPPDIEPRATHHIAEMLTLIGQLIDSGHAYEAQGHVLFAVSRFPAYGAL
SGRSPEDLLAGARVEVAPYKRDPGDFVLWKPSAPDLPGWESPWGRGRPGWHIECSAMSHRYLGESFDIHGGGSDLLFPHH
ENELAQSQCCFPHGRFANHWVHNAMLLVNGEKMSKSLGNFLTVRDALSVSPAEALRLLLLHAQYRSVLNFTLAGLEDAKQ
TLNRFYRAVGDTPPDGTVPVPAPVLAALCDDLNTPRALAEMHALADRALAGDRDAALGLRAAGQLLGLLGQTEDAWFRAG
TYVHPETIERLIVERQDARKSRDFCPRRRYSRKSGEGRHRAGRRAVRHHLEARMTGRDGGADIGPIGNSPVVILVRPQMA
ENIGTTARAMANGGLFHLRLVAPRDGWPLERAWRSASGADRILEAATVHDSVDDAIADLHHVFATCPRPRHIVKTVLTAR
GGAAELRQMSGRGLRTGLLFGPERAGLDNEDMARADALIRYPLNPAFMSLNLAQAVMIMAYEWWMAEDATPPRALMTNET
HVATKGELDNFMRHLIDDLDECGFLRNEQKRAGMVRNLRHFFTRGEVTEQELRTLHGVVTELTRGRRARGQ

Sequences:

>Translated_711_residues
MPDSMPQLTLHDSRSRKTVPFAPLDPGNVRVYYCGPTVYDLAHIGNLRAMVTADILVRLLRHLYPRVTYVRNITDVDDKI
NTRARANGETIDSLTARTIRDFHEDLDAVGILPPDIEPRATHHIAEMLTLIGQLIDSGHAYEAQGHVLFAVSRFPAYGAL
SGRSPEDLLAGARVEVAPYKRDPGDFVLWKPSAPDLPGWESPWGRGRPGWHIECSAMSHRYLGESFDIHGGGSDLLFPHH
ENELAQSQCCFPHGRFANHWVHNAMLLVNGEKMSKSLGNFLTVRDALSVSPAEALRLLLLHAQYRSVLNFTLAGLEDAKQ
TLNRFYRAVGDTPPDGTVPVPAPVLAALCDDLNTPRALAEMHALADRALAGDRDAALGLRAAGQLLGLLGQTEDAWFRAG
TYVHPETIERLIVERQDARKSRDFCPRRRYSRKSGEGRHRAGRRAVRHHLEARMTGRDGGADIGPIGNSPVVILVRPQMA
ENIGTTARAMANGGLFHLRLVAPRDGWPLERAWRSASGADRILEAATVHDSVDDAIADLHHVFATCPRPRHIVKTVLTAR
GGAAELRQMSGRGLRTGLLFGPERAGLDNEDMARADALIRYPLNPAFMSLNLAQAVMIMAYEWWMAEDATPPRALMTNET
HVATKGELDNFMRHLIDDLDECGFLRNEQKRAGMVRNLRHFFTRGEVTEQELRTLHGVVTELTRGRRARGQ
>Mature_710_residues
PDSMPQLTLHDSRSRKTVPFAPLDPGNVRVYYCGPTVYDLAHIGNLRAMVTADILVRLLRHLYPRVTYVRNITDVDDKIN
TRARANGETIDSLTARTIRDFHEDLDAVGILPPDIEPRATHHIAEMLTLIGQLIDSGHAYEAQGHVLFAVSRFPAYGALS
GRSPEDLLAGARVEVAPYKRDPGDFVLWKPSAPDLPGWESPWGRGRPGWHIECSAMSHRYLGESFDIHGGGSDLLFPHHE
NELAQSQCCFPHGRFANHWVHNAMLLVNGEKMSKSLGNFLTVRDALSVSPAEALRLLLLHAQYRSVLNFTLAGLEDAKQT
LNRFYRAVGDTPPDGTVPVPAPVLAALCDDLNTPRALAEMHALADRALAGDRDAALGLRAAGQLLGLLGQTEDAWFRAGT
YVHPETIERLIVERQDARKSRDFCPRRRYSRKSGEGRHRAGRRAVRHHLEARMTGRDGGADIGPIGNSPVVILVRPQMAE
NIGTTARAMANGGLFHLRLVAPRDGWPLERAWRSASGADRILEAATVHDSVDDAIADLHHVFATCPRPRHIVKTVLTARG
GAAELRQMSGRGLRTGLLFGPERAGLDNEDMARADALIRYPLNPAFMSLNLAQAVMIMAYEWWMAEDATPPRALMTNETH
VATKGELDNFMRHLIDDLDECGFLRNEQKRAGMVRNLRHFFTRGEVTEQELRTLHGVVTELTRGRRARGQ

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=357, Percent_Identity=37.5350140056022, Blast_Score=219, Evalue=8e-57,
Organism=Homo sapiens, GI10835051, Length=304, Percent_Identity=37.171052631579, Blast_Score=209, Evalue=6e-54,
Organism=Homo sapiens, GI21269877, Length=304, Percent_Identity=37.171052631579, Blast_Score=209, Evalue=8e-54,
Organism=Homo sapiens, GI62240992, Length=304, Percent_Identity=37.171052631579, Blast_Score=209, Evalue=9e-54,
Organism=Homo sapiens, GI303304987, Length=304, Percent_Identity=37.171052631579, Blast_Score=209, Evalue=1e-53,
Organism=Escherichia coli, GI1786737, Length=427, Percent_Identity=47.7751756440281, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1788881, Length=240, Percent_Identity=32.9166666666667, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790865, Length=151, Percent_Identity=34.4370860927152, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17509797, Length=319, Percent_Identity=33.2288401253918, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17509795, Length=319, Percent_Identity=33.2288401253918, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324082, Length=318, Percent_Identity=33.3333333333333, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI19922218, Length=326, Percent_Identity=38.3435582822086, Blast_Score=220, Evalue=3e-57,
Organism=Drosophila melanogaster, GI19922364, Length=303, Percent_Identity=37.6237623762376, Blast_Score=195, Evalue=9e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 78899; Mature: 78768

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDSMPQLTLHDSRSRKTVPFAPLDPGNVRVYYCGPTVYDLAHIGNLRAMVTADILVRLL
CCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHH
RHLYPRVTYVRNITDVDDKINTRARANGETIDSLTARTIRDFHEDLDAVGILPPDIEPRA
HHHHHHHHHHHCCCCCCHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
THHIAEMLTLIGQLIDSGHAYEAQGHVLFAVSRFPAYGALSGRSPEDLLAGARVEVAPYK
HHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCCCCCCCHHHHHCCCEEEECCCC
RDPGDFVLWKPSAPDLPGWESPWGRGRPGWHIECSAMSHRYLGESFDIHGGGSDLLFPHH
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCEECCCCCCCCCCCC
ENELAQSQCCFPHGRFANHWVHNAMLLVNGEKMSKSLGNFLTVRDALSVSPAEALRLLLL
CCHHHHHHCCCCCCCHHHHHHHCEEEEEECHHHHHHHHHHEEHHHHHCCCHHHHHHHHHH
HAQYRSVLNFTLAGLEDAKQTLNRFYRAVGDTPPDGTVPVPAPVLAALCDDLNTPRALAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHH
MHALADRALAGDRDAALGLRAAGQLLGLLGQTEDAWFRAGTYVHPETIERLIVERQDARK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHH
SRDFCPRRRYSRKSGEGRHRAGRRAVRHHLEARMTGRDGGADIGPIGNSPVVILVRPQMA
HHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCHHH
ENIGTTARAMANGGLFHLRLVAPRDGWPLERAWRSASGADRILEAATVHDSVDDAIADLH
HHCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
HVFATCPRPRHIVKTVLTARGGAAELRQMSGRGLRTGLLFGPERAGLDNEDMARADALIR
HHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCEECEEECCHHCCCCCHHHHHHHHHEE
YPLNPAFMSLNLAQAVMIMAYEWWMAEDATPPRALMTNETHVATKGELDNFMRHLIDDLD
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEECCHHHHHHHHHHHHHHH
ECGFLRNEQKRAGMVRNLRHFFTRGEVTEQELRTLHGVVTELTRGRRARGQ
HHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PDSMPQLTLHDSRSRKTVPFAPLDPGNVRVYYCGPTVYDLAHIGNLRAMVTADILVRLL
CCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHH
RHLYPRVTYVRNITDVDDKINTRARANGETIDSLTARTIRDFHEDLDAVGILPPDIEPRA
HHHHHHHHHHHCCCCCCHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
THHIAEMLTLIGQLIDSGHAYEAQGHVLFAVSRFPAYGALSGRSPEDLLAGARVEVAPYK
HHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCCCCCCCHHHHHCCCEEEECCCC
RDPGDFVLWKPSAPDLPGWESPWGRGRPGWHIECSAMSHRYLGESFDIHGGGSDLLFPHH
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCEECCCCCCCCCCCC
ENELAQSQCCFPHGRFANHWVHNAMLLVNGEKMSKSLGNFLTVRDALSVSPAEALRLLLL
CCHHHHHHCCCCCCCHHHHHHHCEEEEEECHHHHHHHHHHEEHHHHHCCCHHHHHHHHHH
HAQYRSVLNFTLAGLEDAKQTLNRFYRAVGDTPPDGTVPVPAPVLAALCDDLNTPRALAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHH
MHALADRALAGDRDAALGLRAAGQLLGLLGQTEDAWFRAGTYVHPETIERLIVERQDARK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHH
SRDFCPRRRYSRKSGEGRHRAGRRAVRHHLEARMTGRDGGADIGPIGNSPVVILVRPQMA
HHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCHHH
ENIGTTARAMANGGLFHLRLVAPRDGWPLERAWRSASGADRILEAATVHDSVDDAIADLH
HHCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
HVFATCPRPRHIVKTVLTARGGAAELRQMSGRGLRTGLLFGPERAGLDNEDMARADALIR
HHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCEECEEECCHHCCCCCHHHHHHHHHEE
YPLNPAFMSLNLAQAVMIMAYEWWMAEDATPPRALMTNETHVATKGELDNFMRHLIDDLD
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEECCHHHHHHHHHHHHHHH
ECGFLRNEQKRAGMVRNLRHFFTRGEVTEQELRTLHGVVTELTRGRRARGQ
HHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA