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The map label for this gene is dgoA [H]

Identifier: 162147956

GI number: 162147956

Start: 2223360

End: 2224025

Strand: Reverse

Name: dgoA [H]

Synonym: GDI_2172

Alternate gene names: 162147956

Gene position: 2224025-2223360 (Counterclockwise)

Preceding gene: 162147957

Following gene: 162147955

Centisome position: 56.39

GC content: 70.72

Gene sequence:

>666_bases
ATGACGTTCGACCGCGCCCTGGACGTCTGCCCCCTGGTCGCCATCCTACGCGGCATCCGCCCGGACGAGGTGCTGGACAT
CGGTCAGGCGCTGGTCGAAGCGGGCTTCGCGATCATCGAGGTGCCGATGAACTCGCCCGAGCCGCTGCGCAGCATCCGCC
TGCTTCAGGATCGCTTCGGGGATGCCGCGCTGATCGGGGCGGGGACCGTGCTGTCCGCCGAAATGGTGGGGCAGGTGGCC
GATGCCGGAGGGCGGCTGATCGTCATGCCGCATGCCGATGTCGCGGTCATCGGCGCGGCCCGTGCCGCCGGCATGGCCTG
CACCCCCGGCGTCGCCACCCCGACCGAGGGCTTCGCGGCGCTGGCCGCGGGGGCTGCGGCGCTGAAGCTGTTCCCGGCCG
AGCAGATTGGCCCGGGGGCGTTGAAGGCGTGGCGCAGCGTCTTTCCCGCCGGTACGCGCTTCATCCCCGTGGGCGGGATC
ACTCCCGACACGATGGACCCCTGGGTGACGGCCGGCGCGGCGGGGTTCGGGCTGGGATCGGCGCTCTATCGTGCCGGGCG
GTCGGCGGGCGAGGTCGGCGCGACGGCGCGGCTGTTTATCGCCGGCCTGGAAAAAGCCGGTCTGGAAAAATCCAGACTGG
AAAAACAGGAACGGAAACGGACATGA

Upstream 100 bases:

>100_bases
TCGGCAACACCGCGCCGGCCGGGCTGTACCGCATCGCGGTGGAAGCCGGATACCTGCGGCCGACCCCCGAGGAAGATACG
ACACACGGAGATACGACATG

Downstream 100 bases:

>100_bases
AGATCACGAAGCTGACGACGTTCCAGGTCCCGCCGCGCTGGCTGTTCCTGAAGATCGAGACCGACGAGGGGATCAGCGGC
TGGGGTGAGCCGGTGGTCGA

Product: hypothetical protein

Products: NA

Alternate protein names: 2-oxo-3-deoxygalactonate 6-phosphate aldolase; 6-phospho-2-dehydro-3-deoxygalactonate aldolase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTFDRALDVCPLVAILRGIRPDEVLDIGQALVEAGFAIIEVPMNSPEPLRSIRLLQDRFGDAALIGAGTVLSAEMVGQVA
DAGGRLIVMPHADVAVIGAARAAGMACTPGVATPTEGFAALAAGAAALKLFPAEQIGPGALKAWRSVFPAGTRFIPVGGI
TPDTMDPWVTAGAAGFGLGSALYRAGRSAGEVGATARLFIAGLEKAGLEKSRLEKQERKRT

Sequences:

>Translated_221_residues
MTFDRALDVCPLVAILRGIRPDEVLDIGQALVEAGFAIIEVPMNSPEPLRSIRLLQDRFGDAALIGAGTVLSAEMVGQVA
DAGGRLIVMPHADVAVIGAARAAGMACTPGVATPTEGFAALAAGAAALKLFPAEQIGPGALKAWRSVFPAGTRFIPVGGI
TPDTMDPWVTAGAAGFGLGSALYRAGRSAGEVGATARLFIAGLEKAGLEKSRLEKQERKRT
>Mature_220_residues
TFDRALDVCPLVAILRGIRPDEVLDIGQALVEAGFAIIEVPMNSPEPLRSIRLLQDRFGDAALIGAGTVLSAEMVGQVAD
AGGRLIVMPHADVAVIGAARAAGMACTPGVATPTEGFAALAAGAAALKLFPAEQIGPGALKAWRSVFPAGTRFIPVGGIT
PDTMDPWVTAGAAGFGLGSALYRAGRSAGEVGATARLFIAGLEKAGLEKSRLEKQERKRT

Specific function: D-galactonate degradation; first step. D-galactonate degradation; third step. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994954, Length=196, Percent_Identity=47.9591836734694, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI1788156, Length=142, Percent_Identity=30.2816901408451, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.2.21 [H]

Molecular weight: Translated: 22688; Mature: 22556

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00160 ALDOLASE_KDPG_KHG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFDRALDVCPLVAILRGIRPDEVLDIGQALVEAGFAIIEVPMNSPEPLRSIRLLQDRFG
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCC
DAALIGAGTVLSAEMVGQVADAGGRLIVMPHADVAVIGAARAAGMACTPGVATPTEGFAA
CEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEHHHHCCCCCCCCCCCCCHHHHH
LAAGAAALKLFPAEQIGPGALKAWRSVFPAGTRFIPVGGITPDTMDPWVTAGAAGFGLGS
HHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHCCCHHHHHHH
ALYRAGRSAGEVGATARLFIAGLEKAGLEKSRLEKQERKRT
HHHHCCCCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TFDRALDVCPLVAILRGIRPDEVLDIGQALVEAGFAIIEVPMNSPEPLRSIRLLQDRFG
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCC
DAALIGAGTVLSAEMVGQVADAGGRLIVMPHADVAVIGAARAAGMACTPGVATPTEGFAA
CEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEHHHHCCCCCCCCCCCCCHHHHH
LAAGAAALKLFPAEQIGPGALKAWRSVFPAGTRFIPVGGITPDTMDPWVTAGAAGFGLGS
HHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHCCCHHHHHHH
ALYRAGRSAGEVGATARLFIAGLEKAGLEKSRLEKQERKRT
HHHHCCCCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]