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The map label for this gene is lepB [H]

Identifier: 162147938

GI number: 162147938

Start: 2206546

End: 2207478

Strand: Reverse

Name: lepB [H]

Synonym: GDI_2154

Alternate gene names: 162147938

Gene position: 2207478-2206546 (Counterclockwise)

Preceding gene: 162147939

Following gene: 162147937

Centisome position: 55.97

GC content: 64.95

Gene sequence:

>933_bases
GTGCTGCTGGCCAAGCCTTTGCTTGACAGGGGCCGGTCCCCTCGGCTTCATCCGCGGGCCTTGCGGCCGGCCCGCGTCCA
GCCTTGCCCCATCCCATTTCCGGATTCAGATACCAGACCCATGGACGACCCGAACAAGACCCATTCCTCGTCCTTGCCAT
CGGCGGGTGCCGTTCCGGCCTTGCGCGGGCTCTGGGACCTGATCCGCACCATCCTGATCGCCGGCCTGCTGGCGGTGGGC
GTGCGCACGGTACTGTTCGAACCGTTCAACATCCCGTCCGGTTCGATGATTCCGACCCTGCAGGTGGGCGATTACCTGTG
GGTGGCGAAATACAGCTACGGCTATTCGCATTTCTCGCTGCCGCGCTCGCCGGACCTGTTCGACGGCCGCATCTTCGGCA
GCCTGCCGCACCGGGGCGACGTCGCCGTGTTCCGCTTCACCCGGGATACATCGATCGACTACATCAAGCGGATCGTCGGC
CTGCCGGGCGACCGCGTGCAGGTGCGCGGCGGTGAGCTGTACATCAATGATACGCTGGTCCCGCGCGAGGCCAGGGGCAA
TTACGTCGCGGTGGACGAGCACCGCACGCGGATGGAGGGGCAGCGCTACAGCGAAAGCCTGCCTGGAAGCGGCGGCCGCC
CCCCGGTCACGCATGACATCCTGAAGCTGACGAACGAAGGGTTCCAGAACGATACGCCGGTCTATGTCGTGCCGTCGGGC
TATTTCTTCGCCATGGGCGACAATCGCGACGACAGCGCCGACAGCCGCTTCATGGGCGACGACCCGGAAGATCTGGGCTT
TGTGCCGATGGAAAACCTGATCGGGCAGGCCAAATGGATCTTCCTGTCGATCGACGCGCGCTATCCGGCGTGGGAATTCT
GGATGTGGCCGGTCGAGATCCGCTGGGACCGCCTGTTCCAGGGGGTGCGATGA

Upstream 100 bases:

>100_bases
GATGACCGACGAGTACCCGTATGCCTTCGCGCAGGTGATGATCGAAACTGGCCCGCTGCCCTGAAAGCGGGCTAATGTCG
GAACCCGGCAGGCCAGACGG

Downstream 100 bases:

>100_bases
CCGCGTCTGAAAGCGGTGGCGCGGACGGTGTGGTGGCGTCGGTCGAGGCGCGGGTCGGCTACCGGTTCCGCCGCCCCGAC
CTGCTGCGCGAGGCGCTGAC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MLLAKPLLDRGRSPRLHPRALRPARVQPCPIPFPDSDTRPMDDPNKTHSSSLPSAGAVPALRGLWDLIRTILIAGLLAVG
VRTVLFEPFNIPSGSMIPTLQVGDYLWVAKYSYGYSHFSLPRSPDLFDGRIFGSLPHRGDVAVFRFTRDTSIDYIKRIVG
LPGDRVQVRGGELYINDTLVPREARGNYVAVDEHRTRMEGQRYSESLPGSGGRPPVTHDILKLTNEGFQNDTPVYVVPSG
YFFAMGDNRDDSADSRFMGDDPEDLGFVPMENLIGQAKWIFLSIDARYPAWEFWMWPVEIRWDRLFQGVR

Sequences:

>Translated_310_residues
MLLAKPLLDRGRSPRLHPRALRPARVQPCPIPFPDSDTRPMDDPNKTHSSSLPSAGAVPALRGLWDLIRTILIAGLLAVG
VRTVLFEPFNIPSGSMIPTLQVGDYLWVAKYSYGYSHFSLPRSPDLFDGRIFGSLPHRGDVAVFRFTRDTSIDYIKRIVG
LPGDRVQVRGGELYINDTLVPREARGNYVAVDEHRTRMEGQRYSESLPGSGGRPPVTHDILKLTNEGFQNDTPVYVVPSG
YFFAMGDNRDDSADSRFMGDDPEDLGFVPMENLIGQAKWIFLSIDARYPAWEFWMWPVEIRWDRLFQGVR
>Mature_310_residues
MLLAKPLLDRGRSPRLHPRALRPARVQPCPIPFPDSDTRPMDDPNKTHSSSLPSAGAVPALRGLWDLIRTILIAGLLAVG
VRTVLFEPFNIPSGSMIPTLQVGDYLWVAKYSYGYSHFSLPRSPDLFDGRIFGSLPHRGDVAVFRFTRDTSIDYIKRIVG
LPGDRVQVRGGELYINDTLVPREARGNYVAVDEHRTRMEGQRYSESLPGSGGRPPVTHDILKLTNEGFQNDTPVYVVPSG
YFFAMGDNRDDSADSRFMGDDPEDLGFVPMENLIGQAKWIFLSIDARYPAWEFWMWPVEIRWDRLFQGVR

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=265, Percent_Identity=34.3396226415094, Blast_Score=121, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 35004; Mature: 35004

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAKPLLDRGRSPRLHPRALRPARVQPCPIPFPDSDTRPMDDPNKTHSSSLPSAGAVPA
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
LRGLWDLIRTILIAGLLAVGVRTVLFEPFNIPSGSMIPTLQVGDYLWVAKYSYGYSHFSL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEECCCCCCCC
PRSPDLFDGRIFGSLPHRGDVAVFRFTRDTSIDYIKRIVGLPGDRVQVRGGELYINDTLV
CCCCCCCCCEEEECCCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEEECCEEEECCCCC
PREARGNYVAVDEHRTRMEGQRYSESLPGSGGRPPVTHDILKLTNEGFQNDTPVYVVPSG
CHHCCCCEEEECCHHHHHCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECC
YFFAMGDNRDDSADSRFMGDDPEDLGFVPMENLIGQAKWIFLSIDARYPAWEFWMWPVEI
EEEEECCCCCCCCCCCCCCCCHHHCCCCCHHHHCCCEEEEEEEEECCCCCEEEEEEEEEE
RWDRLFQGVR
EHHHHHCCCC
>Mature Secondary Structure
MLLAKPLLDRGRSPRLHPRALRPARVQPCPIPFPDSDTRPMDDPNKTHSSSLPSAGAVPA
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
LRGLWDLIRTILIAGLLAVGVRTVLFEPFNIPSGSMIPTLQVGDYLWVAKYSYGYSHFSL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEECCCCCCCC
PRSPDLFDGRIFGSLPHRGDVAVFRFTRDTSIDYIKRIVGLPGDRVQVRGGELYINDTLV
CCCCCCCCCEEEECCCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEEECCEEEECCCCC
PREARGNYVAVDEHRTRMEGQRYSESLPGSGGRPPVTHDILKLTNEGFQNDTPVYVVPSG
CHHCCCCEEEECCHHHHHCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECC
YFFAMGDNRDDSADSRFMGDDPEDLGFVPMENLIGQAKWIFLSIDARYPAWEFWMWPVEI
EEEEECCCCCCCCCCCCCCCCHHHCCCCCHHHHCCCEEEEEEEEECCCCCEEEEEEEEEE
RWDRLFQGVR
EHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA