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The map label for this gene is pyrH [H]

Identifier: 162147935

GI number: 162147935

Start: 2204002

End: 2204742

Strand: Reverse

Name: pyrH [H]

Synonym: GDI_2151

Alternate gene names: 162147935

Gene position: 2204742-2204002 (Counterclockwise)

Preceding gene: 162147936

Following gene: 162147934

Centisome position: 55.9

GC content: 64.1

Gene sequence:

>741_bases
ATGACAGATCAGGCAACGGAAAAAACCATTGGTTTTCAGCGTGTCCTGCTGAAGGTCTCGGGCGAGGCCCTGATGGGTGA
GGGCTCGTACGGGATCGATCCCGTAATGGTCGACACCATCGCCACCGACATTGCCGAGGTCGCACGTACGGGCGTCGAGA
TCTGTCTGGTCATCGGGGGCGGCAACATCTTTCGCGGCGTCGCGGCGGCGGCGCGCGGCATGGACCGGGCGCAGGGCGAT
TATGCCGGCATGCTGGCCACGGTCATCAACGCCCTGATGGTGCAGAACGCGCTGGAACGGCACGGCGTGCCGACGCGCGT
CATGTCCGCCATCCAGATGTCGTCGGTGGCCGAACCCTATATCCGCAGGCGGGCTGTGCGGCACATGGAAAAGGGCCGTG
TCGTCATCTTCGCGGGGGGCACGGGCAATCCGTTCTTCACCACCGACACGGCGGCGGCGCTGCGGGCGGCGGAAATGGAC
TGCAACGCCCTGCTGAAGGGCACGCAGGTGGACGGCGTCTATTCGGCCGACCCGCGCAAGGTCAAGGACGCGACCCGCTT
CGAACAACTGACGTACCTGGACGTGCTGGCCAAGGACCTGCATGTGATGGATGCCGCCGCGATCAGCCTTGCGCGTGAAA
ACCGCCTGCCGATCGTGGTGTTCAATATTCATGCGCCGGGCGCATTCCCGAAAGTAATGCGCGGCGAAGGCCTGTATACC
CGGATTGTCGAAACGGCCTGA

Upstream 100 bases:

>100_bases
GCTTGTGACCGCTCGCAACCGGCTATAAGAGGGTCTGCATGGGTGAGGTCCCGGCCGGGGCGTCCCCCGCATTCGTTCAT
CTCAGGGATCCGGGGGCGTC

Downstream 100 bases:

>100_bases
CGGGCCGGTTGCTGGAATGAATGAGGATAGGGGGCAGCCGTGACCGTGGCCCCCATGGATGACTATGGAGGGCCGCTGTG
GCTGCTGATCAGAAGACACT

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTDQATEKTIGFQRVLLKVSGEALMGEGSYGIDPVMVDTIATDIAEVARTGVEICLVIGGGNIFRGVAAAARGMDRAQGD
YAGMLATVINALMVQNALERHGVPTRVMSAIQMSSVAEPYIRRRAVRHMEKGRVVIFAGGTGNPFFTTDTAAALRAAEMD
CNALLKGTQVDGVYSADPRKVKDATRFEQLTYLDVLAKDLHVMDAAAISLARENRLPIVVFNIHAPGAFPKVMRGEGLYT
RIVETA

Sequences:

>Translated_246_residues
MTDQATEKTIGFQRVLLKVSGEALMGEGSYGIDPVMVDTIATDIAEVARTGVEICLVIGGGNIFRGVAAAARGMDRAQGD
YAGMLATVINALMVQNALERHGVPTRVMSAIQMSSVAEPYIRRRAVRHMEKGRVVIFAGGTGNPFFTTDTAAALRAAEMD
CNALLKGTQVDGVYSADPRKVKDATRFEQLTYLDVLAKDLHVMDAAAISLARENRLPIVVFNIHAPGAFPKVMRGEGLYT
RIVETA
>Mature_245_residues
TDQATEKTIGFQRVLLKVSGEALMGEGSYGIDPVMVDTIATDIAEVARTGVEICLVIGGGNIFRGVAAAARGMDRAQGDY
AGMLATVINALMVQNALERHGVPTRVMSAIQMSSVAEPYIRRRAVRHMEKGRVVIFAGGTGNPFFTTDTAAALRAAEMDC
NALLKGTQVDGVYSADPRKVKDATRFEQLTYLDVLAKDLHVMDAAAISLARENRLPIVVFNIHAPGAFPKVMRGEGLYTR
IVETA

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=233, Percent_Identity=50.2145922746781, Blast_Score=234, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26416; Mature: 26285

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQATEKTIGFQRVLLKVSGEALMGEGSYGIDPVMVDTIATDIAEVARTGVEICLVIGG
CCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEC
GNIFRGVAAAARGMDRAQGDYAGMLATVINALMVQNALERHGVPTRVMSAIQMSSVAEPY
CHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IRRRAVRHMEKGRVVIFAGGTGNPFFTTDTAAALRAAEMDCNALLKGTQVDGVYSADPRK
HHHHHHHHHHCCCEEEEECCCCCCCEECHHHHHHHHHHCCHHHHHCCCCCCCEECCCCHH
VKDATRFEQLTYLDVLAKDLHVMDAAAISLARENRLPIVVFNIHAPGAFPKVMRGEGLYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHCCCCHHH
RIVETA
HHEECC
>Mature Secondary Structure 
TDQATEKTIGFQRVLLKVSGEALMGEGSYGIDPVMVDTIATDIAEVARTGVEICLVIGG
CCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEC
GNIFRGVAAAARGMDRAQGDYAGMLATVINALMVQNALERHGVPTRVMSAIQMSSVAEPY
CHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IRRRAVRHMEKGRVVIFAGGTGNPFFTTDTAAALRAAEMDCNALLKGTQVDGVYSADPRK
HHHHHHHHHHCCCEEEEECCCCCCCEECHHHHHHHHHHCCHHHHHCCCCCCCEECCCCHH
VKDATRFEQLTYLDVLAKDLHVMDAAAISLARENRLPIVVFNIHAPGAFPKVMRGEGLYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHCCCCHHH
RIVETA
HHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA