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The map label for this gene is lpxA [H]

Identifier: 162147925

GI number: 162147925

Start: 2193173

End: 2194066

Strand: Reverse

Name: lpxA [H]

Synonym: GDI_2141

Alternate gene names: 162147925

Gene position: 2194066-2193173 (Counterclockwise)

Preceding gene: 162147926

Following gene: 162147924

Centisome position: 55.63

GC content: 65.77

Gene sequence:

>894_bases
ATGCTGCTGGGAGAGAGAATGTTGACCGATTTGGCAGGATTGGACGCCGAAACCAGGGCCGCCGAGATTCATCCTTCCTC
GATCGTGGCGAGCGGGGCGCGGATCGGTCATGGGGTTCGGATCGGCCCGTGGTGTTCCATCGGTCCCGACGTGACGATCG
AGGACGGGGTCCATCTGATCGCCAACGTGATCATCGACGGTCATACCCACATCGGTCCCGGGGTCGTCTGCTTTCCGTTC
ACCACCATCGGAATGGCGCCGCAGGACCTGAAATATCGTGGCGAACCCACGCGCTGCACCATCGGTGCGCGCACGGTCAT
CCGCGAAAACGTCACGATCCACCGTGGCACCGCGACGGGCAGCGGGGTCACCCGGGTCGGTGACGACTGCCTGATCATGG
CCAATTCCCATGTGGCGCACGACTGCACCCTGGGGAACGGGGTCATCATCGTGAACAATGTGGTCATGGGCGGCCATGTG
ACGATCGGCGATCATGCGCGGATCATGGGTGCGGCGGCGCTGCACCAGTTCGTCCGTATCGGACGGGCGGCCCTGGTCGG
CGGCGTCTGCGGAGTGGAAGCCGACGTCATTCCCTATGGCAGCGTGCTGGGCAACCGCGCGCGGTTGGTGGGGCTGCACT
GGATCTGGCTGAAGCGCAACGGCGTGCAGCCGGATGAACTGCATCTTCTGCGCCGTGCGTTCCGCGCCCTCTACCCCCGG
GCGATGGACGAGGAATCGACGGCCTTCAGCCGTCGCCTCGCAAGCGTGCGGGCGGATTACGGCAGCGACCCGAAGGTGGC
CGAGATCCTGGCCTTCATCGAGGCCCCCAGCCATCGCGGCCTGGTGCGGGTAGCCGGCGGGGGAGCGGCCTCGATCGAAT
CAGACGGCGTCTGA

Upstream 100 bases:

>100_bases
GGAAATTCAAGGGTATCGCGCGCGTTGACGGCGTGTCGGTGGCCGAAGCCACGTTCAGCGCGATGATCATGGGCTAGCAT
CCTGCCCCGTTGGGGATCGG

Downstream 100 bases:

>100_bases
GTGTCCGGTCGGAAGAACGGGCCGGCGCTGTCGGGCGAGTGCGTGGGAATCCTGGCCGGCGGCGGGCCGCTGCCGGGACA
GGTCGCCCGGGCGGCCGTGG

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLLGERMLTDLAGLDAETRAAEIHPSSIVASGARIGHGVRIGPWCSIGPDVTIEDGVHLIANVIIDGHTHIGPGVVCFPF
TTIGMAPQDLKYRGEPTRCTIGARTVIRENVTIHRGTATGSGVTRVGDDCLIMANSHVAHDCTLGNGVIIVNNVVMGGHV
TIGDHARIMGAAALHQFVRIGRAALVGGVCGVEADVIPYGSVLGNRARLVGLHWIWLKRNGVQPDELHLLRRAFRALYPR
AMDEESTAFSRRLASVRADYGSDPKVAEILAFIEAPSHRGLVRVAGGGAASIESDGV

Sequences:

>Translated_297_residues
MLLGERMLTDLAGLDAETRAAEIHPSSIVASGARIGHGVRIGPWCSIGPDVTIEDGVHLIANVIIDGHTHIGPGVVCFPF
TTIGMAPQDLKYRGEPTRCTIGARTVIRENVTIHRGTATGSGVTRVGDDCLIMANSHVAHDCTLGNGVIIVNNVVMGGHV
TIGDHARIMGAAALHQFVRIGRAALVGGVCGVEADVIPYGSVLGNRARLVGLHWIWLKRNGVQPDELHLLRRAFRALYPR
AMDEESTAFSRRLASVRADYGSDPKVAEILAFIEAPSHRGLVRVAGGGAASIESDGV
>Mature_297_residues
MLLGERMLTDLAGLDAETRAAEIHPSSIVASGARIGHGVRIGPWCSIGPDVTIEDGVHLIANVIIDGHTHIGPGVVCFPF
TTIGMAPQDLKYRGEPTRCTIGARTVIRENVTIHRGTATGSGVTRVGDDCLIMANSHVAHDCTLGNGVIIVNNVVMGGHV
TIGDHARIMGAAALHQFVRIGRAALVGGVCGVEADVIPYGSVLGNRARLVGLHWIWLKRNGVQPDELHLLRRAFRALYPR
AMDEESTAFSRRLASVRADYGSDPKVAEILAFIEAPSHRGLVRVAGGGAASIESDGV

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=267, Percent_Identity=43.8202247191011, Blast_Score=209, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 31414; Mature: 31414

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLGERMLTDLAGLDAETRAAEIHPSSIVASGARIGHGVRIGPWCSIGPDVTIEDGVHLI
CCCHHHHHHHHHCCCCCCCEEECCCHHHHHCCCHHCCCEEECCCCCCCCCEEECCCHHEE
ANVIIDGHTHIGPGVVCFPFTTIGMAPQDLKYRGEPTRCTIGARTVIRENVTIHRGTATG
EHHEECCCCCCCCCEEEECCHHHCCCCCCCCCCCCCCEEEECCCEEEECCCEEEECCCCC
SGVTRVGDDCLIMANSHVAHDCTLGNGVIIVNNVVMGGHVTIGDHARIMGAAALHQFVRI
CCCEECCCCEEEEECCCCEEEEECCCCEEEEEEEEECCEEEECCCHHHHHHHHHHHHHHH
GRAALVGGVCGVEADVIPYGSVLGNRARLVGLHWIWLKRNGVQPDELHLLRRAFRALYPR
HHHHHHCCCCCCCCCCCCCHHHHCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCC
AMDEESTAFSRRLASVRADYGSDPKVAEILAFIEAPSHRGLVRVAGGGAASIESDGV
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MLLGERMLTDLAGLDAETRAAEIHPSSIVASGARIGHGVRIGPWCSIGPDVTIEDGVHLI
CCCHHHHHHHHHCCCCCCCEEECCCHHHHHCCCHHCCCEEECCCCCCCCCEEECCCHHEE
ANVIIDGHTHIGPGVVCFPFTTIGMAPQDLKYRGEPTRCTIGARTVIRENVTIHRGTATG
EHHEECCCCCCCCCEEEECCHHHCCCCCCCCCCCCCCEEEECCCEEEECCCEEEECCCCC
SGVTRVGDDCLIMANSHVAHDCTLGNGVIIVNNVVMGGHVTIGDHARIMGAAALHQFVRI
CCCEECCCCEEEEECCCCEEEEECCCCEEEEEEEEECCEEEECCCHHHHHHHHHHHHHHH
GRAALVGGVCGVEADVIPYGSVLGNRARLVGLHWIWLKRNGVQPDELHLLRRAFRALYPR
HHHHHHCCCCCCCCCCCCCHHHHCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCC
AMDEESTAFSRRLASVRADYGSDPKVAEILAFIEAPSHRGLVRVAGGGAASIESDGV
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA