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The map label for this gene is fabZ

Identifier: 162147926

GI number: 162147926

Start: 2194090

End: 2194575

Strand: Reverse

Name: fabZ

Synonym: GDI_2142

Alternate gene names: 162147926

Gene position: 2194575-2194090 (Counterclockwise)

Preceding gene: 162147927

Following gene: 162147925

Centisome position: 55.64

GC content: 62.76

Gene sequence:

>486_bases
GTGGATAAAGAAGTAGAGGTTCCCCCGGCGGGCGATAGCCCGACCTGCATCGAAGCGATCGACGTGATGCGGATCATGGA
AGCGATACCCCATCGCTATCCGTTCCTGCTGATCGACCGGATGGTCGATATCGTGCTGGGGTCCTCGGCGGTCGGCATCA
AGAACGTGACCGCCAGCGAACCGCATTTCCAGGGGCATTTTCCGGCCCGCCCCGTCATGCCGGGCGTCCTGATCATCGAG
GCGATGGCGCAGACGGCCGCAACCCTGGTGGTGCTGACCCTTGGCCCGGCGTTCGAGGGCAAGCTGGTCTATTTCATGAC
GATCGACGGGGCGAAGTTCCGCCGGCCGGTCGGACCGGGCGACCAGTTGCGTATCCATGTCGAAAAGGAACGCAGCCGCG
CCAACGTATGGAAATTCAAGGGTATCGCGCGCGTTGACGGCGTGTCGGTGGCCGAAGCCACGTTCAGCGCGATGATCATG
GGCTAG

Upstream 100 bases:

>100_bases
GCTGGCCTCCGAACAAGGCCCCCGGAATTCAACCGGGACAGGCGGGCGACGGTCGCAAGGATGACGTGTCCCGCTATCCC
GAGCAAGATGGTCGGACGAC

Downstream 100 bases:

>100_bases
CATCCTGCCCCGTTGGGGATCGGATGCTGCTGGGAGAGAGAATGTTGACCGATTTGGCAGGATTGGACGCCGAAACCAGG
GCCGCCGAGATTCATCCTTC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MDKEVEVPPAGDSPTCIEAIDVMRIMEAIPHRYPFLLIDRMVDIVLGSSAVGIKNVTASEPHFQGHFPARPVMPGVLIIE
AMAQTAATLVVLTLGPAFEGKLVYFMTIDGAKFRRPVGPGDQLRIHVEKERSRANVWKFKGIARVDGVSVAEATFSAMIM
G

Sequences:

>Translated_161_residues
MDKEVEVPPAGDSPTCIEAIDVMRIMEAIPHRYPFLLIDRMVDIVLGSSAVGIKNVTASEPHFQGHFPARPVMPGVLIIE
AMAQTAATLVVLTLGPAFEGKLVYFMTIDGAKFRRPVGPGDQLRIHVEKERSRANVWKFKGIARVDGVSVAEATFSAMIM
G
>Mature_161_residues
MDKEVEVPPAGDSPTCIEAIDVMRIMEAIPHRYPFLLIDRMVDIVLGSSAVGIKNVTASEPHFQGHFPARPVMPGVLIIE
AMAQTAATLVVLTLGPAFEGKLVYFMTIDGAKFRRPVGPGDQLRIHVEKERSRANVWKFKGIARVDGVSVAEATFSAMIM
G

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=140, Percent_Identity=47.8571428571429, Blast_Score=143, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_GLUDA (A9HKU2)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001602387.1
- RefSeq:   YP_002274773.1
- ProteinModelPortal:   A9HKU2
- SMR:   A9HKU2
- GeneID:   5792501
- GeneID:   6973756
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_0362
- HOGENOM:   HBG433282
- OMA:   ILQANIQ
- ProtClustDB:   PRK00006
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.- [C]

Molecular weight: Translated: 17531; Mature: 17531

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: ACT_SITE 66-66

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKEVEVPPAGDSPTCIEAIDVMRIMEAIPHRYPFLLIDRMVDIVLGSSAVGIKNVTASE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
PHFQGHFPARPVMPGVLIIEAMAQTAATLVVLTLGPAFEGKLVYFMTIDGAKFRRPVGPG
CCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEEECCHHHCCCCCCC
DQLRIHVEKERSRANVWKFKGIARVDGVSVAEATFSAMIMG
CEEEEEEECCCCCCCEEEECCEEEECCCHHHHHHHHHEECC
>Mature Secondary Structure
MDKEVEVPPAGDSPTCIEAIDVMRIMEAIPHRYPFLLIDRMVDIVLGSSAVGIKNVTASE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
PHFQGHFPARPVMPGVLIIEAMAQTAATLVVLTLGPAFEGKLVYFMTIDGAKFRRPVGPG
CCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEEECCHHHCCCCCCC
DQLRIHVEKERSRANVWKFKGIARVDGVSVAEATFSAMIMG
CEEEEEEECCCCCCCEEEECCEEEECCCHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA