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The map label for this gene is gcp [H]

Identifier: 162147855

GI number: 162147855

Start: 2115902

End: 2117050

Strand: Direct

Name: gcp [H]

Synonym: GDI_2071

Alternate gene names: 162147855

Gene position: 2115902-2117050 (Clockwise)

Preceding gene: 162147852

Following gene: 162147856

Centisome position: 53.65

GC content: 73.72

Gene sequence:

>1149_bases
ATGATCATGTCCGTGTCCCCTGCCACGCCGCCCGATTCCGCCGAGACAGCGGCGCAAGCCCCTGTTCCGGCGCCCGATAT
GGCGCCCATCCTCGCAATCGAATCGTCCTGCGACGACACGGCCTGGCCATCCTGGCACCCGACGGCACGATCCTGGCCGA
GACCGTTCTGTCGCAGGCCGGACATGTTCCCTTCGGCGGCGTGGTGCCGGAAATCGCGGCCCGGGCCCATCTGGCCGCCC
TGCCGGCCCTGGTACGCCACACGCTGGACGTGGCCGCCCTGCCTGCCGAGGCGCTGGGCGCCGATCGCCGCCAGCACCGG
CCCCGGGCTGATCGGCGGGCTGATCGTCGGCGCCGGCATGGCCAAGGGGCTGGCCGTGGCGCTCGGCCGGCCTTTCGTCG
CCGTGAACCATATCGAGGCCCATGCCCTGACCGCCCGGCTGCCCGGCCTTGTCCCCGGCGGGGCATCGTTTCCCTATCTG
CTGCTGCTGGTCTCGGGCGGCCATTGCCAGTGCATCGCGGTCGAGGGCGTGGGCCGGTATCGCAAGCTGGGCGGCACCAT
CGACGATGCCGCCGGCGAAGCGTTCGACAAGGTCGCGAAGATGCTGGGCCTGGGCTGGCCCGGCGGCCCGGCGGTCGAGG
CCCTGGCGCGCGAGGGCGATCCGGCCCCCTGGCCGCTGCCCCGCCCGCTGCGGGGCCGTCCGGGCTGCGACTTCTCGTTT
TCCGGGCTGAAGACCGCCGTGGCGCAGAAGCTGGCGCCATTCGCGGCCGGCGCCCTGCCCCGGACCGCCGCCGCCGGCAT
TGCCGCCAGTTTCCAGGACGCGGTGGCCGACATCGTCGCCGACCGGGTGGCCCATGCGCTGGACATGATGCCGCAGGCCA
CGCTGCTGGTCGCGGCCGGCGGCGTGGCCGCGAATACGGCCCTGCGCACGCGCCTGACCACCCTTGCGACCTCCCGCGCC
CTGCCCTTCGCGGCGCCTCCCCTGCGGCTGTGTACCGACAATGCGGTCATGGTCGGCTGGGCCGCCATCGAAACCCTGCG
CGAACGCCGGCGGCTGGGGCTGCCGCCCACCGACGACCTTGACCTGCTGCCCCGTCCGCGCTGGCCGCTGGAGCAGATGG
CCGAACGGTTCGCGCACCCCGCCCCATGA

Upstream 100 bases:

>100_bases
CCAGGAACGGACGGAGGAGCGGAAACCATGCGATGTCTCTATTACCGCGACGACACGAAGGAAAGATGACATAGCGCCCG
GCGGAACTGTATTTTATGCA

Downstream 100 bases:

>100_bases
ATTATCGCCACGCCTTTCATGCCGGCAATTTCGCCGATTGCATGAAACATGCGCTGCTGGTGCTGCTGCTACAGGCATTG
GCCCGCAAGCCCGCGCCGTT

Product: O-sialoglycoprotein endopeptidase

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MIMSVSPATPPDSAETAAQAPVPAPDMAPILAIESSCDDTAWPSWHPTARSWPRPFCRRPDMFPSAAWCRKSRPGPIWPP
CRPWYATRWTWPPCLPRRWAPIAASTGPGLIGGLIVGAGMAKGLAVALGRPFVAVNHIEAHALTARLPGLVPGGASFPYL
LLLVSGGHCQCIAVEGVGRYRKLGGTIDDAAGEAFDKVAKMLGLGWPGGPAVEALAREGDPAPWPLPRPLRGRPGCDFSF
SGLKTAVAQKLAPFAAGALPRTAAAGIAASFQDAVADIVADRVAHALDMMPQATLLVAAGGVAANTALRTRLTTLATSRA
LPFAAPPLRLCTDNAVMVGWAAIETLRERRRLGLPPTDDLDLLPRPRWPLEQMAERFAHPAP

Sequences:

>Translated_382_residues
MIMSVSPATPPDSAETAAQAPVPAPDMAPILAIESSCDDTAWPSWHPTARSWPRPFCRRPDMFPSAAWCRKSRPGPIWPP
CRPWYATRWTWPPCLPRRWAPIAASTGPGLIGGLIVGAGMAKGLAVALGRPFVAVNHIEAHALTARLPGLVPGGASFPYL
LLLVSGGHCQCIAVEGVGRYRKLGGTIDDAAGEAFDKVAKMLGLGWPGGPAVEALAREGDPAPWPLPRPLRGRPGCDFSF
SGLKTAVAQKLAPFAAGALPRTAAAGIAASFQDAVADIVADRVAHALDMMPQATLLVAAGGVAANTALRTRLTTLATSRA
LPFAAPPLRLCTDNAVMVGWAAIETLRERRRLGLPPTDDLDLLPRPRWPLEQMAERFAHPAP
>Mature_382_residues
MIMSVSPATPPDSAETAAQAPVPAPDMAPILAIESSCDDTAWPSWHPTARSWPRPFCRRPDMFPSAAWCRKSRPGPIWPP
CRPWYATRWTWPPCLPRRWAPIAASTGPGLIGGLIVGAGMAKGLAVALGRPFVAVNHIEAHALTARLPGLVPGGASFPYL
LLLVSGGHCQCIAVEGVGRYRKLGGTIDDAAGEAFDKVAKMLGLGWPGGPAVEALAREGDPAPWPLPRPLRGRPGCDFSF
SGLKTAVAQKLAPFAAGALPRTAAAGIAASFQDAVADIVADRVAHALDMMPQATLLVAAGGVAANTALRTRLTTLATSRA
LPFAAPPLRLCTDNAVMVGWAAIETLRERRRLGLPPTDDLDLLPRPRWPLEQMAERFAHPAP

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=370, Percent_Identity=32.4324324324324, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI8923380, Length=275, Percent_Identity=30.5454545454545, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1789445, Length=354, Percent_Identity=37.0056497175141, Blast_Score=198, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17557464, Length=347, Percent_Identity=26.8011527377522, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71995670, Length=266, Percent_Identity=30.0751879699248, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320099, Length=391, Percent_Identity=30.690537084399, Blast_Score=150, Evalue=4e-37,
Organism=Drosophila melanogaster, GI20129063, Length=353, Percent_Identity=32.8611898016997, Blast_Score=161, Evalue=6e-40,
Organism=Drosophila melanogaster, GI21357207, Length=262, Percent_Identity=28.2442748091603, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 40357; Mature: 40357

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMSVSPATPPDSAETAAQAPVPAPDMAPILAIESSCDDTAWPSWHPTARSWPRPFCRRP
CEEECCCCCCCCCHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHCCC
DMFPSAAWCRKSRPGPIWPPCRPWYATRWTWPPCLPRRWAPIAASTGPGLIGGLIVGAGM
CCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AKGLAVALGRPFVAVNHIEAHALTARLPGLVPGGASFPYLLLLVSGGHCQCIAVEGVGRY
HHHHHHHHCCCEEEEECHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCHH
RKLGGTIDDAAGEAFDKVAKMLGLGWPGGPAVEALAREGDPAPWPLPRPLRGRPGCDFSF
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
SGLKTAVAQKLAPFAAGALPRTAAAGIAASFQDAVADIVADRVAHALDMMPQATLLVAAG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GVAANTALRTRLTTLATSRALPFAAPPLRLCTDNAVMVGWAAIETLRERRRLGLPPTDDL
CHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCCC
DLLPRPRWPLEQMAERFAHPAP
CCCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MIMSVSPATPPDSAETAAQAPVPAPDMAPILAIESSCDDTAWPSWHPTARSWPRPFCRRP
CEEECCCCCCCCCHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHCCC
DMFPSAAWCRKSRPGPIWPPCRPWYATRWTWPPCLPRRWAPIAASTGPGLIGGLIVGAGM
CCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AKGLAVALGRPFVAVNHIEAHALTARLPGLVPGGASFPYLLLLVSGGHCQCIAVEGVGRY
HHHHHHHHCCCEEEEECHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCHH
RKLGGTIDDAAGEAFDKVAKMLGLGWPGGPAVEALAREGDPAPWPLPRPLRGRPGCDFSF
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
SGLKTAVAQKLAPFAAGALPRTAAAGIAASFQDAVADIVADRVAHALDMMPQATLLVAAG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GVAANTALRTRLTTLATSRALPFAAPPLRLCTDNAVMVGWAAIETLRERRRLGLPPTDDL
CHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCCC
DLLPRPRWPLEQMAERFAHPAP
CCCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA