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The map label for this gene is marC [H]

Identifier: 162147828

GI number: 162147828

Start: 2088132

End: 2088863

Strand: Reverse

Name: marC [H]

Synonym: GDI_2044

Alternate gene names: 162147828

Gene position: 2088863-2088132 (Counterclockwise)

Preceding gene: 162147829

Following gene: 162147822

Centisome position: 52.96

GC content: 69.54

Gene sequence:

>732_bases
ATGCCCCCAGGCCTTCCCGCCGCCGCGCCCCCGGGATGGGGGTACGACCTGTCGGTGTTCAGCGATACCTTCCTGCTGGC
GTTCCCCGCCCTGTTCTCGATCGTGAATCCCATCGGGGCCTCGCTGATCTTCACGCAGGTCACGGCGGGCCGGGCGCGGG
CGGAATCCCTGGCGCTGGCACGGACCGTGGCGCTCTATTCCGCCGTCCTGCTGATCGCGTCGATCTGGATAGGCAGCGCC
ATCCTGGCCTTTTTCGGCATTACCATCGATTCGCTGCGCATTGCCGGCGGGCTGGTGGTCGCGGTGCGCGCCTGGGCGCT
GCTGCAGGCGCCGGAGGAAGCGGCCGCGCGCAAGGAGCAGCAGGCATTGCAGGGCGGCCGGACGGTCGCCGTGCCCCGCT
GGACGGAAATGGCGTTCTTTCCCATGACCATGCCGTTCACGGTCGGGCCGGGCACCATCTCGGTCGCGATCGCGCTCAGT
GCCGGCCGGCCGGCTTCCTCGGGCTGGCTGGTGTTCTATGTCGCGCTGTCACTGGCCGCCATCGTCGTGGCGGGGACGAT
CTGGCTGGCCTATGCCTATGCCGAACGGCTGATGGCGCTGCTGGGCGTGACCGGCGCGCGGATCGTGTCCCGCCTGGCTG
CCCTGATCCTGCTATGCATCGGGGTGCAGATCCTCTCGGCGGGGATCAAGGGACTGGCCCTGACCATCGTCCGGGCCGCC
GTCGCGTCCTGA

Upstream 100 bases:

>100_bases
CCCCCGCCCCGGCGGACGGGGCTTGACGGGCCCGCGGGCTTCGGAAAAGACGATAGGCTGATCCCGGCCTTACGGGGATC
GGCCCTTTGGAAGAACCGCC

Downstream 100 bases:

>100_bases
CGGCGGGTCGAGCAGCGGCCGGATGGCGGCACGCAGCGCCGGGATCACCTCGGCCGTGAACCACGGATTCCGGCGCTCCC
ATGCCCCGGTGCGCCAGGAC

Product: multiple antibiotic resistance protein marC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MPPGLPAAAPPGWGYDLSVFSDTFLLAFPALFSIVNPIGASLIFTQVTAGRARAESLALARTVALYSAVLLIASIWIGSA
ILAFFGITIDSLRIAGGLVVAVRAWALLQAPEEAAARKEQQALQGGRTVAVPRWTEMAFFPMTMPFTVGPGTISVAIALS
AGRPASSGWLVFYVALSLAAIVVAGTIWLAYAYAERLMALLGVTGARIVSRLAALILLCIGVQILSAGIKGLALTIVRAA
VAS

Sequences:

>Translated_243_residues
MPPGLPAAAPPGWGYDLSVFSDTFLLAFPALFSIVNPIGASLIFTQVTAGRARAESLALARTVALYSAVLLIASIWIGSA
ILAFFGITIDSLRIAGGLVVAVRAWALLQAPEEAAARKEQQALQGGRTVAVPRWTEMAFFPMTMPFTVGPGTISVAIALS
AGRPASSGWLVFYVALSLAAIVVAGTIWLAYAYAERLMALLGVTGARIVSRLAALILLCIGVQILSAGIKGLALTIVRAA
VAS
>Mature_242_residues
PPGLPAAAPPGWGYDLSVFSDTFLLAFPALFSIVNPIGASLIFTQVTAGRARAESLALARTVALYSAVLLIASIWIGSAI
LAFFGITIDSLRIAGGLVVAVRAWALLQAPEEAAARKEQQALQGGRTVAVPRWTEMAFFPMTMPFTVGPGTISVAIALSA
GRPASSGWLVFYVALSLAAIVVAGTIWLAYAYAERLMALLGVTGARIVSRLAALILLCIGVQILSAGIKGLALTIVRAAV
AS

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787494, Length=220, Percent_Identity=29.0909090909091, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787809, Length=201, Percent_Identity=29.8507462686567, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 25181; Mature: 25050

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPGLPAAAPPGWGYDLSVFSDTFLLAFPALFSIVNPIGASLIFTQVTAGRARAESLALA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTVALYSAVLLIASIWIGSAILAFFGITIDSLRIAGGLVVAVRAWALLQAPEEAAARKEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QALQGGRTVAVPRWTEMAFFPMTMPFTVGPGTISVAIALSAGRPASSGWLVFYVALSLAA
HHHHCCCEEECCCHHHHEEEEEECCEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHH
IVVAGTIWLAYAYAERLMALLGVTGARIVSRLAALILLCIGVQILSAGIKGLALTIVRAA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAS
HCC
>Mature Secondary Structure 
PPGLPAAAPPGWGYDLSVFSDTFLLAFPALFSIVNPIGASLIFTQVTAGRARAESLALA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTVALYSAVLLIASIWIGSAILAFFGITIDSLRIAGGLVVAVRAWALLQAPEEAAARKEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QALQGGRTVAVPRWTEMAFFPMTMPFTVGPGTISVAIALSAGRPASSGWLVFYVALSLAA
HHHHCCCEEECCCHHHHEEEEEECCEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHH
IVVAGTIWLAYAYAERLMALLGVTGARIVSRLAALILLCIGVQILSAGIKGLALTIVRAA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAS
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]