Click here to switch to the map view.

The map label for this gene is adhA [H]

Identifier: 162147824

GI number: 162147824

Start: 2083010

End: 2085220

Strand: Direct

Name: adhA [H]

Synonym: GDI_2040

Alternate gene names: 162147824

Gene position: 2083010-2085220 (Clockwise)

Preceding gene: 162147823

Following gene: 162147825

Centisome position: 52.81

GC content: 63.77

Gene sequence:

>2211_bases
ATGCGAGCCGTTTACGGGAAAAGACGTTCTCTCCGCGGAACGCTTGCCGTCGGAACGATATGCGCCGCGACATTCTTTGG
ATATACGGCGGCGACCAGTGCCGCCGAATCCGAATTCGGCGCGACGGGTGAAGCAATTATCCATGCGGACGACCATCCCG
GCGACTGGCTGACCTACGGCCGCACCTATTCCGAGCAGCGTTATAGCCCGCTGGACCAGATCAACCGGTCCAATGTCGGC
AACCTGAAGCTGGCCTGGTATTACGACCTGGACACCAACCGTGGGCAGGAAGGCACGCCGCTGATCGTCGATGGCGTGAT
GTACGCCACCACGAACTGGAGCAAGATGAAGGCCCTGGACGCGGCCACGGGCAAGCTGCTGTGGGCGTACGACCCCCGCG
TGCCCGGCAATATCGCCGACAAGGGATGCTGTGACACCGTCAATCGCGGTGCGGCCTACTGGAACGGCAAGGTCTATTTC
GGCACGTTCGACGGAAGGCTGATCGCGCTGGACGCCAAGACCGGCAAGCTGGTCTGGAGCGTGAACACCATCCCCGCCGA
CGCGGCCCTGGGCCACCAGCGTTCCTACACCGTGGACGGCGCGCCGCGTATCGCCAAGGGCCGGGTCATCATCGGCAATG
GTGGATCGGAATTCGGCGCGCGCGGCTTCGTTTCGGCCTTCGACGCCGAGACCGGCAAGCTGGACTGGCGCTTCTACACG
GTGCCGAATGCGCAGAACAAGCCGGACAACGCGCCGTCCGACGCTGTCCTGATGAGCAAGGCGTACCCGACCTGGAGCCC
GACCGGCGCATGGACGACCCAGGGCGGCGGCGGCACGGTATGGGATTCGATCGTCTATGACCCCGTGACCGATCTGGTCT
ATCTGGGCGTGGGCAACGGGTCGCCCTGGAACTACAAGTTCCGTTCCGACGGCAAGGGCGATAACCTGTTCCTGGGCAGC
ATCGTCGCGCTCAAGCCCGAAACCGGCGAATATGTCTGGCATTTCCAGGAAACGCCGATGGACCAGTGGGACTATACCTC
GGTCCAGCAGATCATGACGCTGGATCTGCCCATCAACGGGCAGACGCGGCATGTCATCGTCCATGCGCCGAAGAACGGCT
TCTTCTACATCATCGACGCCAAGACCGGCGAATTCCTGTCGGGCAAGAACTATGTCTACGTGAACTGGGCCAGCGGCCTG
GACCCGAAGACCGGCCGTCCGATCTATAACCCGGATGCGCTCTATACCCTGAACGGCAAGGAATGGTACGGCATCCCGGG
CGATCTGGGCGGCCACAATTTCGCGGCCATGGCCTTCAGCCCCCGGACCGGACTGGTCTATATCCCGGCCCAGCAGGTGC
CATTCCTGTATACGAGCCAGGTCGGCGGCTTCAAGCCGCATCCGGACAGCTGGAATCTCGGCCTCGACATGAACAAGGTC
GGCGTCACGGATTCGCCCGAGGCCAAGCAGGCCTTCATCAAGGACCTGAAGGGCTGGATCGTCGCCTGGGACCCGGTGAA
GCAGCAGGAAGCGTTCCGCGTCGACCACAAAGGCCCGTGGAATGGCGGTATCGTGGCCACCGGCGGCGACCTGCTGTTCC
AGGGCCTGGCGAACGGCGAATTCCATGCCTACGACGCCACCAACGGCGCCGACCTGTTCCACTTCGCGGCGCAGAGCGGC
ATCATCGCCCCGCCGGTCACCTACATGGCCAACGGCAAGCAGTATGTCGCGGTCGAGGTCGGATGGGGCGGCATCTATCC
GTTCTTCCTGGGTGGCCTGGCGCGGACCAGCGGCTGGACCGTCAACCATTCGCGCGTCATCGCCTTCTCGCTCGACGGCG
CGGCCAAGTTGCCGCCGCAGAACGACAAGGGCTTCCTGCCCGTCAAGCCGCCCGCCCAGTTCGACGGCAAGCGGACCGAC
AACGGGTATTTCGAGTTCCAGACCTTCTGCGCGGCCTGCCATGGCGACAATGCCGAGGCCGGCGGCGTGCTGCCCGACCT
GCGCTGGTCCGGCGCGATCCGCCATCAGGACGCGTTCTATAACGTGGTCGGCCGCGGCGCCCTGACGGCATACGGCATGG
ATCGGTTCGATGCCTCGATGAAGCCGGAGCAGATCGAGGACATCCGGCAATTCCTGATCAAGCGTTCCAACGACACCTAC
CAGAGGGAGGTTGATGCCCGGAAGAACGTGGACGGCATACCCGCACAGTGA

Upstream 100 bases:

>100_bases
CTGTCACAACAGTCACATTATGTTCGCATCGAACGGACCGTCTGCGGTCCGGACCCGGATTCATCCGGTTTTTTCTTTTG
TCACGAGGACATCGGACATG

Downstream 100 bases:

>100_bases
CGTCTTTCCCTACGGTTTTTCGGATTTTCCGCATCAACACGACGCATGGTGAACAGAATGCTCAACAGGCTTAAGGTTGC
GATCGGCACGGCGGCGTTCA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 736; Mature: 736

Protein sequence:

>736_residues
MRAVYGKRRSLRGTLAVGTICAATFFGYTAATSAAESEFGATGEAIIHADDHPGDWLTYGRTYSEQRYSPLDQINRSNVG
NLKLAWYYDLDTNRGQEGTPLIVDGVMYATTNWSKMKALDAATGKLLWAYDPRVPGNIADKGCCDTVNRGAAYWNGKVYF
GTFDGRLIALDAKTGKLVWSVNTIPADAALGHQRSYTVDGAPRIAKGRVIIGNGGSEFGARGFVSAFDAETGKLDWRFYT
VPNAQNKPDNAPSDAVLMSKAYPTWSPTGAWTTQGGGGTVWDSIVYDPVTDLVYLGVGNGSPWNYKFRSDGKGDNLFLGS
IVALKPETGEYVWHFQETPMDQWDYTSVQQIMTLDLPINGQTRHVIVHAPKNGFFYIIDAKTGEFLSGKNYVYVNWASGL
DPKTGRPIYNPDALYTLNGKEWYGIPGDLGGHNFAAMAFSPRTGLVYIPAQQVPFLYTSQVGGFKPHPDSWNLGLDMNKV
GVTDSPEAKQAFIKDLKGWIVAWDPVKQQEAFRVDHKGPWNGGIVATGGDLLFQGLANGEFHAYDATNGADLFHFAAQSG
IIAPPVTYMANGKQYVAVEVGWGGIYPFFLGGLARTSGWTVNHSRVIAFSLDGAAKLPPQNDKGFLPVKPPAQFDGKRTD
NGYFEFQTFCAACHGDNAEAGGVLPDLRWSGAIRHQDAFYNVVGRGALTAYGMDRFDASMKPEQIEDIRQFLIKRSNDTY
QREVDARKNVDGIPAQ

Sequences:

>Translated_736_residues
MRAVYGKRRSLRGTLAVGTICAATFFGYTAATSAAESEFGATGEAIIHADDHPGDWLTYGRTYSEQRYSPLDQINRSNVG
NLKLAWYYDLDTNRGQEGTPLIVDGVMYATTNWSKMKALDAATGKLLWAYDPRVPGNIADKGCCDTVNRGAAYWNGKVYF
GTFDGRLIALDAKTGKLVWSVNTIPADAALGHQRSYTVDGAPRIAKGRVIIGNGGSEFGARGFVSAFDAETGKLDWRFYT
VPNAQNKPDNAPSDAVLMSKAYPTWSPTGAWTTQGGGGTVWDSIVYDPVTDLVYLGVGNGSPWNYKFRSDGKGDNLFLGS
IVALKPETGEYVWHFQETPMDQWDYTSVQQIMTLDLPINGQTRHVIVHAPKNGFFYIIDAKTGEFLSGKNYVYVNWASGL
DPKTGRPIYNPDALYTLNGKEWYGIPGDLGGHNFAAMAFSPRTGLVYIPAQQVPFLYTSQVGGFKPHPDSWNLGLDMNKV
GVTDSPEAKQAFIKDLKGWIVAWDPVKQQEAFRVDHKGPWNGGIVATGGDLLFQGLANGEFHAYDATNGADLFHFAAQSG
IIAPPVTYMANGKQYVAVEVGWGGIYPFFLGGLARTSGWTVNHSRVIAFSLDGAAKLPPQNDKGFLPVKPPAQFDGKRTD
NGYFEFQTFCAACHGDNAEAGGVLPDLRWSGAIRHQDAFYNVVGRGALTAYGMDRFDASMKPEQIEDIRQFLIKRSNDTY
QREVDARKNVDGIPAQ
>Mature_736_residues
MRAVYGKRRSLRGTLAVGTICAATFFGYTAATSAAESEFGATGEAIIHADDHPGDWLTYGRTYSEQRYSPLDQINRSNVG
NLKLAWYYDLDTNRGQEGTPLIVDGVMYATTNWSKMKALDAATGKLLWAYDPRVPGNIADKGCCDTVNRGAAYWNGKVYF
GTFDGRLIALDAKTGKLVWSVNTIPADAALGHQRSYTVDGAPRIAKGRVIIGNGGSEFGARGFVSAFDAETGKLDWRFYT
VPNAQNKPDNAPSDAVLMSKAYPTWSPTGAWTTQGGGGTVWDSIVYDPVTDLVYLGVGNGSPWNYKFRSDGKGDNLFLGS
IVALKPETGEYVWHFQETPMDQWDYTSVQQIMTLDLPINGQTRHVIVHAPKNGFFYIIDAKTGEFLSGKNYVYVNWASGL
DPKTGRPIYNPDALYTLNGKEWYGIPGDLGGHNFAAMAFSPRTGLVYIPAQQVPFLYTSQVGGFKPHPDSWNLGLDMNKV
GVTDSPEAKQAFIKDLKGWIVAWDPVKQQEAFRVDHKGPWNGGIVATGGDLLFQGLANGEFHAYDATNGADLFHFAAQSG
IIAPPVTYMANGKQYVAVEVGWGGIYPFFLGGLARTSGWTVNHSRVIAFSLDGAAKLPPQNDKGFLPVKPPAQFDGKRTD
NGYFEFQTFCAACHGDNAEAGGVLPDLRWSGAIRHQDAFYNVVGRGALTAYGMDRFDASMKPEQIEDIRQFLIKRSNDTY
QREVDARKNVDGIPAQ

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is not a substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=381, Percent_Identity=30.7086614173228, Blast_Score=129, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF00034 Cytochrom_C; PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 80519; Mature: 80519

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00363 BACTERIAL_PQQ_1 ; PS00364 BACTERIAL_PQQ_2 ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVYGKRRSLRGTLAVGTICAATFFGYTAATSAAESEFGATGEAIIHADDHPGDWLTYG
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEECCCCCCEEECC
RTYSEQRYSPLDQINRSNVGNLKLAWYYDLDTNRGQEGTPLIVDGVMYATTNWSKMKALD
CCCCHHHCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEEEECCCHHHHHHH
AATGKLLWAYDPRVPGNIADKGCCDTVNRGAAYWNGKVYFGTFDGRLIALDAKTGKLVWS
HCCCCEEEEECCCCCCCCCCCCCHHHHHCCCEEECCEEEEEECCCEEEEEECCCCEEEEE
VNTIPADAALGHQRSYTVDGAPRIAKGRVIIGNGGSEFGARGFVSAFDAETGKLDWRFYT
EECCCCHHHCCCCCEEEECCCCCEECCEEEECCCCCCCCCCCCEEEECCCCCEEEEEEEE
VPNAQNKPDNAPSDAVLMSKAYPTWSPTGAWTTQGGGGTVWDSIVYDPVTDLVYLGVGNG
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCHHHHHHCCCCCEEEEECCCC
SPWNYKFRSDGKGDNLFLGSIVALKPETGEYVWHFQETPMDQWDYTSVQQIMTLDLPING
CCCEEEECCCCCCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCC
QTRHVIVHAPKNGFFYIIDAKTGEFLSGKNYVYVNWASGLDPKTGRPIYNPDALYTLNGK
CCEEEEEECCCCCEEEEEECCCCCEECCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCC
EWYGIPGDLGGHNFAAMAFSPRTGLVYIPAQQVPFLYTSQVGGFKPHPDSWNLGLDMNKV
EEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCC
GVTDSPEAKQAFIKDLKGWIVAWDPVKQQEAFRVDHKGPWNGGIVATGGDLLFQGLANGE
CCCCCCHHHHHHHHHCCCEEEEECCCCCCHHEECCCCCCCCCCEEEECHHHHHHHCCCCE
FHAYDATNGADLFHFAAQSGIIAPPVTYMANGKQYVAVEVGWGGIYPFFLGGLARTSGWT
EEEEECCCCCHHHHHHHCCCCCCCCHHEEECCCEEEEEEECCCCCHHHHHCCHHHCCCEE
VNHSRVIAFSLDGAAKLPPQNDKGFLPVKPPAQFDGKRTDNGYFEFQTFCAACHGDNAEA
EECCEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCC
GGVLPDLRWSGAIRHQDAFYNVVGRGALTAYGMDRFDASMKPEQIEDIRQFLIKRSNDTY
CCCCCCCCCCCCEECCCHHHHHHCCCEEEECCCHHHCCCCCHHHHHHHHHHHHCCCCCHH
QREVDARKNVDGIPAQ
HHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRAVYGKRRSLRGTLAVGTICAATFFGYTAATSAAESEFGATGEAIIHADDHPGDWLTYG
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEECCCCCCEEECC
RTYSEQRYSPLDQINRSNVGNLKLAWYYDLDTNRGQEGTPLIVDGVMYATTNWSKMKALD
CCCCHHHCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEEEECCCHHHHHHH
AATGKLLWAYDPRVPGNIADKGCCDTVNRGAAYWNGKVYFGTFDGRLIALDAKTGKLVWS
HCCCCEEEEECCCCCCCCCCCCCHHHHHCCCEEECCEEEEEECCCEEEEEECCCCEEEEE
VNTIPADAALGHQRSYTVDGAPRIAKGRVIIGNGGSEFGARGFVSAFDAETGKLDWRFYT
EECCCCHHHCCCCCEEEECCCCCEECCEEEECCCCCCCCCCCCEEEECCCCCEEEEEEEE
VPNAQNKPDNAPSDAVLMSKAYPTWSPTGAWTTQGGGGTVWDSIVYDPVTDLVYLGVGNG
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCHHHHHHCCCCCEEEEECCCC
SPWNYKFRSDGKGDNLFLGSIVALKPETGEYVWHFQETPMDQWDYTSVQQIMTLDLPING
CCCEEEECCCCCCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCC
QTRHVIVHAPKNGFFYIIDAKTGEFLSGKNYVYVNWASGLDPKTGRPIYNPDALYTLNGK
CCEEEEEECCCCCEEEEEECCCCCEECCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCC
EWYGIPGDLGGHNFAAMAFSPRTGLVYIPAQQVPFLYTSQVGGFKPHPDSWNLGLDMNKV
EEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCC
GVTDSPEAKQAFIKDLKGWIVAWDPVKQQEAFRVDHKGPWNGGIVATGGDLLFQGLANGE
CCCCCCHHHHHHHHHCCCEEEEECCCCCCHHEECCCCCCCCCCEEEECHHHHHHHCCCCE
FHAYDATNGADLFHFAAQSGIIAPPVTYMANGKQYVAVEVGWGGIYPFFLGGLARTSGWT
EEEEECCCCCHHHHHHHCCCCCCCCHHEEECCCEEEEEEECCCCCHHHHHCCHHHCCCEE
VNHSRVIAFSLDGAAKLPPQNDKGFLPVKPPAQFDGKRTDNGYFEFQTFCAACHGDNAEA
EECCEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCC
GGVLPDLRWSGAIRHQDAFYNVVGRGALTAYGMDRFDASMKPEQIEDIRQFLIKRSNDTY
CCCCCCCCCCCCEECCCHHHHHHCCCEEEECCCHHHCCCCCHHHHHHHHHHHHCCCCCHH
QREVDARKNVDGIPAQ
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA