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The map label for this gene is cyoA [H]

Identifier: 162147819

GI number: 162147819

Start: 2078520

End: 2079467

Strand: Reverse

Name: cyoA [H]

Synonym: GDI_2035

Alternate gene names: 162147819

Gene position: 2079467-2078520 (Counterclockwise)

Preceding gene: 162147820

Following gene: 162147818

Centisome position: 52.72

GC content: 57.17

Gene sequence:

>948_bases
ATGTCGAAACCAACGAGGCGTGAGATGAAGAAAAAAATCTTGCCAAGATTATCGAATTTATTGTGTTTGTCCTCAGCGTT
CCTCTTGGCGGGATGTGACTGGGTGACCCTCAACCCCAAGGGCGTCATCGGTGTTCAGGAAAAGAGCCTGATCCTGAGCG
CGACCTACGCGATGCTGCTGGTCGTCGTGCCGGTCATCGTCCTGACGCTGCTGTTCGCGTGGCAGTACCGCCAGTCGAAC
ACGAGCGCCGAATATCTTCCGAAATGGGCGCATTCCAACAAGATCGAGGTCGTGATCTGGCTCGTGCCCAGCCTGATCAT
CCTGTTCCTGGCGGTCCTGACCTATCAGACCTGCCATTCGCTCGACCCCTATCGCCCGATCGATGACGAAACGAACGTGA
AGCCGATTCATGTCGATGTCGTCGCCCTGGACTGGAAGTGGCTGTTCATCTACCCCGACGAGGGGATCGCCACCGTCAAC
CAGATGGCCTTCCCGGTGAATACGCCGGTCGATTTCCGGATCACCTCTGATTCGGTCATGAACTCGTTCTTCATTCCGCA
GCTCGGCTCGCAGGTCTACGCCATGGCCGGCATGCGCACGCAGCTTCACCTGATTGCCAACGAAGCCGGCAACTACCTGG
GTGAATCGGCCAACTTCAGCGGCCGCGGCTTCTCGGACATGCAGTTCCGCGCGCTGGCGATGAGCAACGACGACTACAAC
GCCTGGGTCCAGAAGGTTAAGGCGTCCTCCGAACAGCTCGACGGTTCGAACTATCCCAAGCTGGCGGCGCCCAGCGAGAA
GAACCCGGTCGAGTATTTCTCGCACGTTTCATCCAGCTTCTTCGATGGGATCGTGGCCAAGTACAACAACGGCATGATCA
TGGATGAGGGCACGGGCAAGTTGAAGCCGGTGCAGTCCGCAATGTCCGACATGAATATGAAGGAATAG

Upstream 100 bases:

>100_bases
TGAAGAACGGTGGGATGCCTGATCGGGTTCCGCAGTAAACATGAAACGTGACCGTTGTTGTTTTAAGCCCGTGGACGAAG
CGAGCATGTGAGCAAGGGTG

Downstream 100 bases:

>100_bases
GACAGATGTTAGGAAAATTAAGCTGGTCGGACATCCCGTTCGATGTGCCGATTCTTGTTGGAACCTTCGCCGGCGTCGCG
ATCGTCGGGCTGGCCGTCCT

Product: ubiquinol oxidase subunit 2

Products: NA

Alternate protein names: Cytochrome A1 subunit 2; Oxidase BA(3) subunit 2; Ubiquinol oxidase polypeptide II [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSKPTRREMKKKILPRLSNLLCLSSAFLLAGCDWVTLNPKGVIGVQEKSLILSATYAMLLVVVPVIVLTLLFAWQYRQSN
TSAEYLPKWAHSNKIEVVIWLVPSLIILFLAVLTYQTCHSLDPYRPIDDETNVKPIHVDVVALDWKWLFIYPDEGIATVN
QMAFPVNTPVDFRITSDSVMNSFFIPQLGSQVYAMAGMRTQLHLIANEAGNYLGESANFSGRGFSDMQFRALAMSNDDYN
AWVQKVKASSEQLDGSNYPKLAAPSEKNPVEYFSHVSSSFFDGIVAKYNNGMIMDEGTGKLKPVQSAMSDMNMKE

Sequences:

>Translated_315_residues
MSKPTRREMKKKILPRLSNLLCLSSAFLLAGCDWVTLNPKGVIGVQEKSLILSATYAMLLVVVPVIVLTLLFAWQYRQSN
TSAEYLPKWAHSNKIEVVIWLVPSLIILFLAVLTYQTCHSLDPYRPIDDETNVKPIHVDVVALDWKWLFIYPDEGIATVN
QMAFPVNTPVDFRITSDSVMNSFFIPQLGSQVYAMAGMRTQLHLIANEAGNYLGESANFSGRGFSDMQFRALAMSNDDYN
AWVQKVKASSEQLDGSNYPKLAAPSEKNPVEYFSHVSSSFFDGIVAKYNNGMIMDEGTGKLKPVQSAMSDMNMKE
>Mature_314_residues
SKPTRREMKKKILPRLSNLLCLSSAFLLAGCDWVTLNPKGVIGVQEKSLILSATYAMLLVVVPVIVLTLLFAWQYRQSNT
SAEYLPKWAHSNKIEVVIWLVPSLIILFLAVLTYQTCHSLDPYRPIDDETNVKPIHVDVVALDWKWLFIYPDEGIATVNQ
MAFPVNTPVDFRITSDSVMNSFFIPQLGSQVYAMAGMRTQLHLIANEAGNYLGESANFSGRGFSDMQFRALAMSNDDYNA
WVQKVKASSEQLDGSNYPKLAAPSEKNPVEYFSHVSSSFFDGIVAKYNNGMIMDEGTGKLKPVQSAMSDMNMKE

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI1786635, Length=308, Percent_Identity=50.6493506493506, Blast_Score=312, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012141
- InterPro:   IPR010514
- InterPro:   IPR008972
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- InterPro:   IPR006333 [H]

Pfam domain/function: PF00116 COX2; PF06481 COX_ARM [H]

EC number: 1.10.3.-

Molecular weight: Translated: 35270; Mature: 35139

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPTRREMKKKILPRLSNLLCLSSAFLLAGCDWVTLNPKGVIGVQEKSLILSATYAMLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCHHHHHHHHHHHH
VVVPVIVLTLLFAWQYRQSNTSAEYLPKWAHSNKIEVVIWLVPSLIILFLAVLTYQTCHS
HHHHHHHHHHHHHHHHHCCCCCHHHCCHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHC
LDPYRPIDDETNVKPIHVDVVALDWKWLFIYPDEGIATVNQMAFPVNTPVDFRITSDSVM
CCCCCCCCCCCCCEEEEEEEEEEEEEEEEEECCCCCHHHHHEEECCCCCEEEEECCHHHH
NSFFIPQLGSQVYAMAGMRTQLHLIANEAGNYLGESANFSGRGFSDMQFRALAMSNDDYN
HHHHHHHHCCHHHHHHCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCHH
AWVQKVKASSEQLDGSNYPKLAAPSEKNPVEYFSHVSSSFFDGIVAKYNNGMIMDEGTGK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
LKPVQSAMSDMNMKE
CHHHHHHHHCCCCCC
>Mature Secondary Structure 
SKPTRREMKKKILPRLSNLLCLSSAFLLAGCDWVTLNPKGVIGVQEKSLILSATYAMLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCHHHHHHHHHHHH
VVVPVIVLTLLFAWQYRQSNTSAEYLPKWAHSNKIEVVIWLVPSLIILFLAVLTYQTCHS
HHHHHHHHHHHHHHHHHCCCCCHHHCCHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHC
LDPYRPIDDETNVKPIHVDVVALDWKWLFIYPDEGIATVNQMAFPVNTPVDFRITSDSVM
CCCCCCCCCCCCCEEEEEEEEEEEEEEEEEECCCCCHHHHHEEECCCCCEEEEECCHHHH
NSFFIPQLGSQVYAMAGMRTQLHLIANEAGNYLGESANFSGRGFSDMQFRALAMSNDDYN
HHHHHHHHCCHHHHHHCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCHH
AWVQKVKASSEQLDGSNYPKLAAPSEKNPVEYFSHVSSSFFDGIVAKYNNGMIMDEGTGK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
LKPVQSAMSDMNMKE
CHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8392509 [H]