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The map label for this gene is cyoB [H]

Identifier: 162147818

GI number: 162147818

Start: 2076520

End: 2078514

Strand: Reverse

Name: cyoB [H]

Synonym: GDI_2034

Alternate gene names: 162147818

Gene position: 2078514-2076520 (Counterclockwise)

Preceding gene: 162147819

Following gene: 162147817

Centisome position: 52.7

GC content: 60.9

Gene sequence:

>1995_bases
ATGTTAGGAAAATTAAGCTGGTCGGACATCCCGTTCGATGTGCCGATTCTTGTTGGAACCTTCGCCGGCGTCGCGATCGT
CGGGCTGGCCGTCCTTGGCCTGATCACCTATTACGGCAAGTGGGGCTATCTCTGGAAAGAGTGGCTCACCTCGGTCGATC
ACAAGCGTCTCGGCGTGATGTATATCGTCTTGGCCCTGCTCGCCCTTGCCCGCGGCTTCGCGGACGCCGTCATGATGCGC
TCGCAGCTCGCGCTGGCCTATGCCGGCAATCCGGGCTACCTGCCGCCGCACCATTACGACCAGATCTTCTCGGCCCACGG
CACCATCATGATCTTCTTCATGGCGATGGCGTTCATGAGCGGACTGATGAACGTGATCGTGCCGCTGCAGATCGGTGCCC
GCGACGTGGCCTTCCCGTTCGTGAACTCGGTCAGCTTCTGGATGACGACGATCAGCTTCGTCCTGATCAACATCTCGCTG
TTCATCGGCGAGTTCTCGCAGTGCGGCTGGCTGGCGTATCCGCCCCTGTCGGAACTGCAGTTCAGCCCCGGCGTCGGCGT
CGACTACTACATCTGGGCCGTGCAGCTTTCGGGTGTCGGCACGCTGCTGACGGGCATCAACTTCTTCACGACCATCGTGA
AGATGCGCGCCCCCGGCATGACCTTCATGAAGATGCCGGTGTTCACCTGGACCATCCTCTGCAACACCGTGCTGATCATG
GTGGCGTTCCCGTTCCTGACGGTGGCCCTGGCTCTGCTGGGTCTGGACCGTTATTTCGGGATGCACTTCTTCACCAATGA
CGGTGGCGGCAACCAGATGCTGTACCTCAACCTGATCTGGGCGTGGGGTCATCCGGAAGTCTACATCCTGGTCCTGCCGG
CCTTCGGCGCGTTCTCGGAAATCACGCAGACCTTCTCGCGCAAGCCGCTGTTCGGCTACAACACCATGGTCTACGCGACC
TGCTCGATCATGGGCCTGTCGCTGGTGGTATGGGCGCATCACTTCTTCACCATGGGCGCCGGCGCCAACGTCAACGCGTT
CTTCGGCATCATGACGATGATCATCGCGATCCCGACGGGCGTGAAGATCTTCAACTGGCTGTTCACCATCTACAAGGGCC
GTGTTGAGTTCAACGGCATCATGTACTGGGTGATCGGCTTCATGGTCACCTTCTCCATCGGTGGCATGACCGGCGTCATG
CTGGCCATCCCGGCCGCCGACTTCGTCCTGCACAACAGCCTGTTCGTCATCGCCCACTTCCACAACGTCATCATCGGCGG
TGTGTATTTCGGTTATGTCGCCGCGATGGCTTTCTGGTGGCCGAAGGCTTTCGGCTTCAAGATGAACGAAGCCTGGGGCA
AGCGTGCCTTCTGGTGCTGGCTCGTGGGTTTCTACATGGCGTTCATGCCGCTCTATGTCCTGGGTTTCGAGGGCATGACG
CGTCGCATGGACCACTATGACAACCCGGCCTGGCATCCGTGGATGGTGATGGCCTCGATCGGCGCCGCGATCGTCGCGCT
GGGCGTGGTCTGCCAGCTGACCCAGATCTATGTCTCGATCCGTGACCGCAACCTGCCGGAAAGCCGTGACCTGACGGGCG
ATCCGTGGAATGCGCGCACGCTGGAATGGTCCACCTCGTCCCCGCCGCCGTTCTACAACTTCGCGGTTGTGCCCACGGTG
CACGAGCTGGATGCCTTCGCCCACGACAAGGAAGCCGGCATCGACACCCGTTCGGCCGGTGCGACCTATCAGCCGATCCA
CATGCCGAAGAACACGTCGGCTGGCTTCTTCATCGGTGTGTTCAGCCTGATCCTCGGCTTCGCCGCGGTCTGGTACATCT
GGTGGCTCGCGGCTGTCGGCCTGCTCGGTGTCATTGGGACCCTGATCGCGCGGAGCAGCAACAACGACGTCGACTACTAC
GTGCCGGCGGCCGAAGTTGCCCGTATCGAGAACGAGCATACCCGTAACCTCTTGGCAGCACAGGCGGCGGAATAA

Upstream 100 bases:

>100_bases
TGGCCAAGTACAACAACGGCATGATCATGGATGAGGGCACGGGCAAGTTGAAGCCGGTGCAGTCCGCAATGTCCGACATG
AATATGAAGGAATAGGACAG

Downstream 100 bases:

>100_bases
TGGCGCACGATATAACTGCTGACGCGGCCCACGCCCACGAGGAACACCACGAATCTCCGGTGGTGTTCGGGTTCTGGCTG
TATCTGATGACGGACTGCCT

Product: ubiquinol oxidase subunit 1

Products: NA

Alternate protein names: Cytochrome A1 subunit 1; Oxidase BA(3) subunit 1; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MLGKLSWSDIPFDVPILVGTFAGVAIVGLAVLGLITYYGKWGYLWKEWLTSVDHKRLGVMYIVLALLALARGFADAVMMR
SQLALAYAGNPGYLPPHHYDQIFSAHGTIMIFFMAMAFMSGLMNVIVPLQIGARDVAFPFVNSVSFWMTTISFVLINISL
FIGEFSQCGWLAYPPLSELQFSPGVGVDYYIWAVQLSGVGTLLTGINFFTTIVKMRAPGMTFMKMPVFTWTILCNTVLIM
VAFPFLTVALALLGLDRYFGMHFFTNDGGGNQMLYLNLIWAWGHPEVYILVLPAFGAFSEITQTFSRKPLFGYNTMVYAT
CSIMGLSLVVWAHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFNWLFTIYKGRVEFNGIMYWVIGFMVTFSIGGMTGVM
LAIPAADFVLHNSLFVIAHFHNVIIGGVYFGYVAAMAFWWPKAFGFKMNEAWGKRAFWCWLVGFYMAFMPLYVLGFEGMT
RRMDHYDNPAWHPWMVMASIGAAIVALGVVCQLTQIYVSIRDRNLPESRDLTGDPWNARTLEWSTSSPPPFYNFAVVPTV
HELDAFAHDKEAGIDTRSAGATYQPIHMPKNTSAGFFIGVFSLILGFAAVWYIWWLAAVGLLGVIGTLIARSSNNDVDYY
VPAAEVARIENEHTRNLLAAQAAE

Sequences:

>Translated_664_residues
MLGKLSWSDIPFDVPILVGTFAGVAIVGLAVLGLITYYGKWGYLWKEWLTSVDHKRLGVMYIVLALLALARGFADAVMMR
SQLALAYAGNPGYLPPHHYDQIFSAHGTIMIFFMAMAFMSGLMNVIVPLQIGARDVAFPFVNSVSFWMTTISFVLINISL
FIGEFSQCGWLAYPPLSELQFSPGVGVDYYIWAVQLSGVGTLLTGINFFTTIVKMRAPGMTFMKMPVFTWTILCNTVLIM
VAFPFLTVALALLGLDRYFGMHFFTNDGGGNQMLYLNLIWAWGHPEVYILVLPAFGAFSEITQTFSRKPLFGYNTMVYAT
CSIMGLSLVVWAHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFNWLFTIYKGRVEFNGIMYWVIGFMVTFSIGGMTGVM
LAIPAADFVLHNSLFVIAHFHNVIIGGVYFGYVAAMAFWWPKAFGFKMNEAWGKRAFWCWLVGFYMAFMPLYVLGFEGMT
RRMDHYDNPAWHPWMVMASIGAAIVALGVVCQLTQIYVSIRDRNLPESRDLTGDPWNARTLEWSTSSPPPFYNFAVVPTV
HELDAFAHDKEAGIDTRSAGATYQPIHMPKNTSAGFFIGVFSLILGFAAVWYIWWLAAVGLLGVIGTLIARSSNNDVDYY
VPAAEVARIENEHTRNLLAAQAAE
>Mature_664_residues
MLGKLSWSDIPFDVPILVGTFAGVAIVGLAVLGLITYYGKWGYLWKEWLTSVDHKRLGVMYIVLALLALARGFADAVMMR
SQLALAYAGNPGYLPPHHYDQIFSAHGTIMIFFMAMAFMSGLMNVIVPLQIGARDVAFPFVNSVSFWMTTISFVLINISL
FIGEFSQCGWLAYPPLSELQFSPGVGVDYYIWAVQLSGVGTLLTGINFFTTIVKMRAPGMTFMKMPVFTWTILCNTVLIM
VAFPFLTVALALLGLDRYFGMHFFTNDGGGNQMLYLNLIWAWGHPEVYILVLPAFGAFSEITQTFSRKPLFGYNTMVYAT
CSIMGLSLVVWAHHFFTMGAGANVNAFFGIMTMIIAIPTGVKIFNWLFTIYKGRVEFNGIMYWVIGFMVTFSIGGMTGVM
LAIPAADFVLHNSLFVIAHFHNVIIGGVYFGYVAAMAFWWPKAFGFKMNEAWGKRAFWCWLVGFYMAFMPLYVLGFEGMT
RRMDHYDNPAWHPWMVMASIGAAIVALGVVCQLTQIYVSIRDRNLPESRDLTGDPWNARTLEWSTSSPPPFYNFAVVPTV
HELDAFAHDKEAGIDTRSAGATYQPIHMPKNTSAGFFIGVFSLILGFAAVWYIWWLAAVGLLGVIGTLIARSSNNDVDYY
VPAAEVARIENEHTRNLLAAQAAE

Specific function: Catalytic subunit of the enzyme. Electrons originating in a quinol are transferred to the bimetallic center formed by heme a and copper B [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=37.8167641325536, Blast_Score=329, Evalue=5e-90,
Organism=Escherichia coli, GI1786634, Length=660, Percent_Identity=67.2727272727273, Blast_Score=934, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=36.1581920903955, Blast_Score=332, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6226524, Length=327, Percent_Identity=41.2844036697248, Blast_Score=245, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=34.412955465587, Blast_Score=139, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 73998; Mature: 73998

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGKLSWSDIPFDVPILVGTFAGVAIVGLAVLGLITYYGKWGYLWKEWLTSVDHKRLGVM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHH
YIVLALLALARGFADAVMMRSQLALAYAGNPGYLPPHHYDQIFSAHGTIMIFFMAMAFMS
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
GLMNVIVPLQIGARDVAFPFVNSVSFWMTTISFVLINISLFIGEFSQCGWLAYPPLSELQ
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHCC
FSPGVGVDYYIWAVQLSGVGTLLTGINFFTTIVKMRAPGMTFMKMPVFTWTILCNTVLIM
CCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VAFPFLTVALALLGLDRYFGMHFFTNDGGGNQMLYLNLIWAWGHPEVYILVLPAFGAFSE
HHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEEEEEEECCCCEEEEEEEECCCCHHH
ITQTFSRKPLFGYNTMVYATCSIMGLSLVVWAHHFFTMGAGANVNAFFGIMTMIIAIPTG
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
VKIFNWLFTIYKGRVEFNGIMYWVIGFMVTFSIGGMTGVMLAIPAADFVLHNSLFVIAHF
HHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEHH
HNVIIGGVYFGYVAAMAFWWPKAFGFKMNEAWGKRAFWCWLVGFYMAFMPLYVLGFEGMT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHH
RRMDHYDNPAWHPWMVMASIGAAIVALGVVCQLTQIYVSIRDRNLPESRDLTGDPWNART
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
LEWSTSSPPPFYNFAVVPTVHELDAFAHDKEAGIDTRSAGATYQPIHMPKNTSAGFFIGV
EEECCCCCCCCEEEEECCCHHHHHHHHCCHHCCCCCCCCCCCCCCEECCCCCCCHHHHHH
FSLILGFAAVWYIWWLAAVGLLGVIGTLIARSSNNDVDYYVPAAEVARIENEHTRNLLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHCCHHHHHHHHH
QAAE
HCCC
>Mature Secondary Structure
MLGKLSWSDIPFDVPILVGTFAGVAIVGLAVLGLITYYGKWGYLWKEWLTSVDHKRLGVM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHH
YIVLALLALARGFADAVMMRSQLALAYAGNPGYLPPHHYDQIFSAHGTIMIFFMAMAFMS
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
GLMNVIVPLQIGARDVAFPFVNSVSFWMTTISFVLINISLFIGEFSQCGWLAYPPLSELQ
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHCC
FSPGVGVDYYIWAVQLSGVGTLLTGINFFTTIVKMRAPGMTFMKMPVFTWTILCNTVLIM
CCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VAFPFLTVALALLGLDRYFGMHFFTNDGGGNQMLYLNLIWAWGHPEVYILVLPAFGAFSE
HHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEEEEEEECCCCEEEEEEEECCCCHHH
ITQTFSRKPLFGYNTMVYATCSIMGLSLVVWAHHFFTMGAGANVNAFFGIMTMIIAIPTG
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
VKIFNWLFTIYKGRVEFNGIMYWVIGFMVTFSIGGMTGVMLAIPAADFVLHNSLFVIAHF
HHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEHH
HNVIIGGVYFGYVAAMAFWWPKAFGFKMNEAWGKRAFWCWLVGFYMAFMPLYVLGFEGMT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHH
RRMDHYDNPAWHPWMVMASIGAAIVALGVVCQLTQIYVSIRDRNLPESRDLTGDPWNART
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
LEWSTSSPPPFYNFAVVPTVHELDAFAHDKEAGIDTRSAGATYQPIHMPKNTSAGFFIGV
EEECCCCCCCCEEEEECCCHHHHHHHHCCHHCCCCCCCCCCCCCCEECCCCCCCHHHHHH
FSLILGFAAVWYIWWLAAVGLLGVIGTLIARSSNNDVDYYVPAAEVARIENEHTRNLLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHCCHHHHHHHHH
QAAE
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8392509 [H]