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The map label for this gene is tolC [H]

Identifier: 162147800

GI number: 162147800

Start: 2057336

End: 2058862

Strand: Reverse

Name: tolC [H]

Synonym: GDI_2016

Alternate gene names: 162147800

Gene position: 2058862-2057336 (Counterclockwise)

Preceding gene: 162147801

Following gene: 162147798

Centisome position: 52.2

GC content: 67.78

Gene sequence:

>1527_bases
ATGCTCGGGCTGGCCGGTTGCGCCACCCAAGCCCTGCATTCGGCGCCGGACCGGCCCGACGCGCCCTGGCGCCCCAATGT
CTCGGCTGCCGGCGAGATCATTCCCGGTCCATGCTGCGCGCGCGGGCTTGCGTTGCCCCCGGGCTACAGCCTGCCGTCCA
ACCGGAATATCCAGGGCCGTCCGGCGCCGCCCGAACTGCAAGGCGCGCATCCCTATTCGCTTGCCGAACTGATCGACATC
GCGCAATCCACCAACCCGGACACCAGGCGCGCCTGGAATACGGCGCGCGACGCGGCGCTGGCGGTGGGCATCGCGCGCAG
CACCTATCTGCCGCACCTGACGGCCACCGTGGTGGGCGGCTACAATCATGCGCACGATAGCGGCGCCAACGCGGCCATCG
GCAACGTCGATATCGGCGGCACAAGCACGCGGGTGGGCAACGGCGAGGTGCAGACGCTCGGCCTGGAGTGGCTGCTGTTC
GATTTCGGCAAGCGCGAGGCCACGATCGACGCCGCCAGACAGAGCCAGCTCGCCACCAACATCCTGTTCACGGGCGCGCA
TCAGAAACTGATCTACGCCGTAACGCTCGCCTTCTATACCCACGCCGCGGCGACCGCGCGGGTCACCCTGCTCCATCAGG
CGCTGGACAATGCGCGCAAGGTCGAGGATGCCGCGGACATGCGGTTACGTCGCGGCCAGGGTACCGTCGTGGATGCGACC
CAGGCGAGGCAGGCGACCGCCCAGGCCGAACTGCGGCTGGTTCAGGCCGAGGGCGGTGCGGAGAACACCTATCTCGACCT
GATGACGGCCATCGGCATCCCGCCCGGCACGCACGTGCTGACGCAGGATATTTCCGACCGGCCGCTCAGCCTCGCCGACG
CGCGCCTGACCGACGACATGATCCAGCGCGACGCCGCGCGACGGCCGGACGTCCTGGCCGCCTATGCCACTGCCCGCGCA
TCACGCAGCGCGGTCGCGGCGGCGCGGGCGGAGTTCCTGCCCAAGATCTTCGTCAGCGGCAATGTGGCATACGCGACCGG
GCGTCTGGCCTTGTCCTCCGTGCCCGGAATCGGCGCGAATGCCGCGCCGACGCTCAATCTGTCGTCGAACAATTTCAGCA
GCCTGATCCTGGGCGGCATCACCGTGCCAATCTTCGATGGCGGCATGCGTGCCGCGGCATTGAAACAGGCCAGGAATCGA
TTCGACAGCGCCGAGACGAATTTGCGCCAGACCCTGGATGAAGCGGTCAAGCAATTGGTTGTCGCCGAAAATGGTGTCCA
CACGAGCCTGAGCGCCTATGCCGCGTCCGGACGCCTGCAAACGGCGGCGCAGACGAGCTTCGACGCCACATTGTCCGCCT
ACCGCAACGGCGTCGGGTCCATCACCCAGGCCACGCTGGCGCAAAGCGGTCTGATCGATGCAAGGCTGGAGCGATCGGAT
GCCTATTACGCCGCCCTGATCGCCGCCTCCAGCCTCGCTTTCGCGGCGGGCGCATTGGGGGATGCGTCCCCAACCGAGCA
GCCGTGA

Upstream 100 bases:

>100_bases
TGATTCCCGAACGCGATGCCCAGACGCGCGCACGTTTCGAACGGTTGGAGAGCCTGGCCTCGTGACCCGTCCCGCCTCCC
TCGCAACCATCGGGTTCGCC

Downstream 100 bases:

>100_bases
CCGCGTCGGCGGACTAGTCGGCTCACTCGGCGGCGCTTTCCTCGATCGCCGCCTCGGCCAGCAGCCACTCCTCCTCGGCC
TCTTCCTGCTCGCGCCCGAT

Product: outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MLGLAGCATQALHSAPDRPDAPWRPNVSAAGEIIPGPCCARGLALPPGYSLPSNRNIQGRPAPPELQGAHPYSLAELIDI
AQSTNPDTRRAWNTARDAALAVGIARSTYLPHLTATVVGGYNHAHDSGANAAIGNVDIGGTSTRVGNGEVQTLGLEWLLF
DFGKREATIDAARQSQLATNILFTGAHQKLIYAVTLAFYTHAAATARVTLLHQALDNARKVEDAADMRLRRGQGTVVDAT
QARQATAQAELRLVQAEGGAENTYLDLMTAIGIPPGTHVLTQDISDRPLSLADARLTDDMIQRDAARRPDVLAAYATARA
SRSAVAAARAEFLPKIFVSGNVAYATGRLALSSVPGIGANAAPTLNLSSNNFSSLILGGITVPIFDGGMRAAALKQARNR
FDSAETNLRQTLDEAVKQLVVAENGVHTSLSAYAASGRLQTAAQTSFDATLSAYRNGVGSITQATLAQSGLIDARLERSD
AYYAALIAASSLAFAAGALGDASPTEQP

Sequences:

>Translated_508_residues
MLGLAGCATQALHSAPDRPDAPWRPNVSAAGEIIPGPCCARGLALPPGYSLPSNRNIQGRPAPPELQGAHPYSLAELIDI
AQSTNPDTRRAWNTARDAALAVGIARSTYLPHLTATVVGGYNHAHDSGANAAIGNVDIGGTSTRVGNGEVQTLGLEWLLF
DFGKREATIDAARQSQLATNILFTGAHQKLIYAVTLAFYTHAAATARVTLLHQALDNARKVEDAADMRLRRGQGTVVDAT
QARQATAQAELRLVQAEGGAENTYLDLMTAIGIPPGTHVLTQDISDRPLSLADARLTDDMIQRDAARRPDVLAAYATARA
SRSAVAAARAEFLPKIFVSGNVAYATGRLALSSVPGIGANAAPTLNLSSNNFSSLILGGITVPIFDGGMRAAALKQARNR
FDSAETNLRQTLDEAVKQLVVAENGVHTSLSAYAASGRLQTAAQTSFDATLSAYRNGVGSITQATLAQSGLIDARLERSD
AYYAALIAASSLAFAAGALGDASPTEQP
>Mature_508_residues
MLGLAGCATQALHSAPDRPDAPWRPNVSAAGEIIPGPCCARGLALPPGYSLPSNRNIQGRPAPPELQGAHPYSLAELIDI
AQSTNPDTRRAWNTARDAALAVGIARSTYLPHLTATVVGGYNHAHDSGANAAIGNVDIGGTSTRVGNGEVQTLGLEWLLF
DFGKREATIDAARQSQLATNILFTGAHQKLIYAVTLAFYTHAAATARVTLLHQALDNARKVEDAADMRLRRGQGTVVDAT
QARQATAQAELRLVQAEGGAENTYLDLMTAIGIPPGTHVLTQDISDRPLSLADARLTDDMIQRDAARRPDVLAAYATARA
SRSAVAAARAEFLPKIFVSGNVAYATGRLALSSVPGIGANAAPTLNLSSNNFSSLILGGITVPIFDGGMRAAALKQARNR
FDSAETNLRQTLDEAVKQLVVAENGVHTSLSAYAASGRLQTAAQTSFDATLSAYRNGVGSITQATLAQSGLIDARLERSD
AYYAALIAASSLAFAAGALGDASPTEQP

Specific function: Required for proper expression of outer membrane protein genes such as ompF, nmpC, protein 2, hemolysin, colicin V, or colicin E1. May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=406, Percent_Identity=23.1527093596059, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082199, Length=450, Percent_Identity=23.7777777777778, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53048; Mature: 53048

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGLAGCATQALHSAPDRPDAPWRPNVSAAGEIIPGPCCARGLALPPGYSLPSNRNIQGR
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCC
PAPPELQGAHPYSLAELIDIAQSTNPDTRRAWNTARDAALAVGIARSTYLPHLTATVVGG
CCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHEECC
YNHAHDSGANAAIGNVDIGGTSTRVGNGEVQTLGLEWLLFDFGKREATIDAARQSQLATN
CCCCCCCCCCCEECCEECCCCCEECCCCCEEEEEHEEEEECCCCCHHHHHHHHHHHHHHH
ILFTGAHQKLIYAVTLAFYTHAAATARVTLLHQALDNARKVEDAADMRLRRGQGTVVDAT
HEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHH
QARQATAQAELRLVQAEGGAENTYLDLMTAIGIPPGTHVLTQDISDRPLSLADARLTDDM
HHHHHHHHHHEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHH
IQRDAARRPDVLAAYATARASRSAVAAARAEFLPKIFVSGNVAYATGRLALSSVPGIGAN
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCEEECCCCCCCCC
AAPTLNLSSNNFSSLILGGITVPIFDGGMRAAALKQARNRFDSAETNLRQTLDEAVKQLV
CCCEEEECCCCCCCEEECCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VAENGVHTSLSAYAASGRLQTAAQTSFDATLSAYRNGVGSITQATLAQSGLIDARLERSD
HHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHCC
AYYAALIAASSLAFAAGALGDASPTEQP
HHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLGLAGCATQALHSAPDRPDAPWRPNVSAAGEIIPGPCCARGLALPPGYSLPSNRNIQGR
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCC
PAPPELQGAHPYSLAELIDIAQSTNPDTRRAWNTARDAALAVGIARSTYLPHLTATVVGG
CCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHEECC
YNHAHDSGANAAIGNVDIGGTSTRVGNGEVQTLGLEWLLFDFGKREATIDAARQSQLATN
CCCCCCCCCCCEECCEECCCCCEECCCCCEEEEEHEEEEECCCCCHHHHHHHHHHHHHHH
ILFTGAHQKLIYAVTLAFYTHAAATARVTLLHQALDNARKVEDAADMRLRRGQGTVVDAT
HEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHH
QARQATAQAELRLVQAEGGAENTYLDLMTAIGIPPGTHVLTQDISDRPLSLADARLTDDM
HHHHHHHHHHEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHH
IQRDAARRPDVLAAYATARASRSAVAAARAEFLPKIFVSGNVAYATGRLALSSVPGIGAN
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCEEECCCCCCCCC
AAPTLNLSSNNFSSLILGGITVPIFDGGMRAAALKQARNRFDSAETNLRQTLDEAVKQLV
CCCEEEECCCCCCCEEECCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VAENGVHTSLSAYAASGRLQTAAQTSFDATLSAYRNGVGSITQATLAQSGLIDARLERSD
HHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHCC
AYYAALIAASSLAFAAGALGDASPTEQP
HHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8801424 [H]