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The map label for this gene is purN [H]

Identifier: 162147797

GI number: 162147797

Start: 2054085

End: 2054723

Strand: Direct

Name: purN [H]

Synonym: GDI_2013

Alternate gene names: 162147797

Gene position: 2054085-2054723 (Clockwise)

Preceding gene: 162147796

Following gene: 162147799

Centisome position: 52.08

GC content: 71.83

Gene sequence:

>639_bases
GTGACGCACGACACCCACGCCGCCGCCCGGCGGCCGATCGCGATTCTGATCAGCGGGCGCGGCAGCAACATGCGCGCGCT
GATCGATGCCTGCGCGGCGCCGGACTTCCCGGCCCGTATCGCCCTGGTCCTGAGCAACCGGCCCGACGCGCCGGGGCTGG
AGGTCGCGCGCGCGGCGGGCCTGCGGGCCGAGGCGATCGATCACCGTCCCTTTCGCGGCGACCGCGCGGCGCATGAACAC
GCGATCGACGCCACCCTGCGCGCGGCCGGGGTCGAACTGGTCTGCCTGGCCGGCTACATGCGCCTGCTGACCCCGTTCCT
GACCGGGGCCTGGGCGGGGCGGATGCTGAACATCCATCCCAGCCTGCTGCCGGCATTTCCGGGCCTGCACACGCATGAAC
GCGCCCTGCAGGCCGGGGTGAAGCTGCATGGCTGTACGGTGCATCTGGTCACGGAAATCATGGATGACGGCCCGATCCTG
GGCCAGGCCGCCGTGCCCGTCCACGCGGACGACACCCCGGACCGGCTGGCGGCACGGGTGCTGGAACAGGAACACCGCCT
GTATCCGGCGGCCCTGCGCAAGGTCCTGACGCCCGATGCCGTGCCGCAGCCGGATATCGGGTCTCTGCTGTTCCTGTAG

Upstream 100 bases:

>100_bases
GGTCAGGACGCGTTCGTCATCGGCCGGCTGGAAGAGGGCACGCCCGGCGCCGCCGCCGGCCTGCGCTTCACCACCCGGCC
CGACTTCACCGGATAAGCCT

Downstream 100 bases:

>100_bases
GAACCCGGTCGGCATGACGGGCACCCTGGCGGGTGCCCGTCCGGCGTGATCAGGGCAGGATTTCGGTCTGGGCGAAGAAG
AACGCGATTTCGGTGTTCGC

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTHDTHAAARRPIAILISGRGSNMRALIDACAAPDFPARIALVLSNRPDAPGLEVARAAGLRAEAIDHRPFRGDRAAHEH
AIDATLRAAGVELVCLAGYMRLLTPFLTGAWAGRMLNIHPSLLPAFPGLHTHERALQAGVKLHGCTVHLVTEIMDDGPIL
GQAAVPVHADDTPDRLAARVLEQEHRLYPAALRKVLTPDAVPQPDIGSLLFL

Sequences:

>Translated_212_residues
MTHDTHAAARRPIAILISGRGSNMRALIDACAAPDFPARIALVLSNRPDAPGLEVARAAGLRAEAIDHRPFRGDRAAHEH
AIDATLRAAGVELVCLAGYMRLLTPFLTGAWAGRMLNIHPSLLPAFPGLHTHERALQAGVKLHGCTVHLVTEIMDDGPIL
GQAAVPVHADDTPDRLAARVLEQEHRLYPAALRKVLTPDAVPQPDIGSLLFL
>Mature_211_residues
THDTHAAARRPIAILISGRGSNMRALIDACAAPDFPARIALVLSNRPDAPGLEVARAAGLRAEAIDHRPFRGDRAAHEHA
IDATLRAAGVELVCLAGYMRLLTPFLTGAWAGRMLNIHPSLLPAFPGLHTHERALQAGVKLHGCTVHLVTEIMDDGPILG
QAAVPVHADDTPDRLAARVLEQEHRLYPAALRKVLTPDAVPQPDIGSLLFL

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=193, Percent_Identity=44.559585492228, Blast_Score=168, Evalue=3e-42,
Organism=Homo sapiens, GI209869995, Length=193, Percent_Identity=44.559585492228, Blast_Score=168, Evalue=3e-42,
Organism=Homo sapiens, GI209869993, Length=193, Percent_Identity=44.559585492228, Blast_Score=168, Evalue=3e-42,
Organism=Escherichia coli, GI1788846, Length=177, Percent_Identity=46.3276836158192, Blast_Score=163, Evalue=8e-42,
Organism=Escherichia coli, GI1787483, Length=189, Percent_Identity=29.6296296296296, Blast_Score=77, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17567511, Length=186, Percent_Identity=40.8602150537634, Blast_Score=150, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24582400, Length=209, Percent_Identity=43.0622009569378, Blast_Score=168, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 22716; Mature: 22584

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHDTHAAARRPIAILISGRGSNMRALIDACAAPDFPARIALVLSNRPDAPGLEVARAAG
CCCCCCHHHCCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHCC
LRAEAIDHRPFRGDRAAHEHAIDATLRAAGVELVCLAGYMRLLTPFLTGAWAGRMLNIHP
CHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCEEECCH
SLLPAFPGLHTHERALQAGVKLHGCTVHLVTEIMDDGPILGQAAVPVHADDTPDRLAARV
HHHHCCCCCCHHHHHHHCCCEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
LEQEHRLYPAALRKVLTPDAVPQPDIGSLLFL
HHHHHCCCHHHHHHHHCCCCCCCCCCCCEECC
>Mature Secondary Structure 
THDTHAAARRPIAILISGRGSNMRALIDACAAPDFPARIALVLSNRPDAPGLEVARAAG
CCCCCHHHCCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHCC
LRAEAIDHRPFRGDRAAHEHAIDATLRAAGVELVCLAGYMRLLTPFLTGAWAGRMLNIHP
CHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCEEECCH
SLLPAFPGLHTHERALQAGVKLHGCTVHLVTEIMDDGPILGQAAVPVHADDTPDRLAARV
HHHHCCCCCCHHHHHHHCCCEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
LEQEHRLYPAALRKVLTPDAVPQPDIGSLLFL
HHHHHCCCHHHHHHHHCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]