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The map label for this gene is yheS [H]

Identifier: 162147799

GI number: 162147799

Start: 2055436

End: 2057313

Strand: Direct

Name: yheS [H]

Synonym: GDI_2015

Alternate gene names: 162147799

Gene position: 2055436-2057313 (Clockwise)

Preceding gene: 162147797

Following gene: 162147804

Centisome position: 52.11

GC content: 71.88

Gene sequence:

>1878_bases
GTGAGCCTGCTCGTCATTTCCGACCTGACCCTTCGCATCGCGGGACGCACCCTGCTGGACGGCGCGTCGCTGACCGTCGA
TCCGGGGCGCAAGATCGGCCTGGTCGGGCGGAACGGGGCCGGAAAATCCACCCTGCTGGCCGCGATCGCGGGCGATATCG
CACCGGACGGCGGCACCATCCACCTGTCGTCGCGCGCGCGCATGGCCCGCATCCGGCAGGAAGCCCCGTCGGGCGACGCC
AACCTGCTGGACACGGTGCTGGCCGGCGACGCCGAACGCACCGCCCTGATGGCCGAAGCCGACCAGACCCCCGACCCGGT
GCGGCTGGCCGACATCCATGAACGGCTGCGGGCGATCGGGGCCGACAGCGCGCCCGCGCGCGCCGCGACCATCCTGTCGG
GCCTGGGCTTCGACGCCGACGCCCAGGCCCGCCCGGTGTCGGATTTTTCCGGCGGCTGGCGCATGCGCGTGGCGCTGGCC
ACGGCGCTGTTCCTCAACCCCGACCTGCTGCTGCTGGACGAACCGACCAACCATCTGGACCTGGATGCCACGATCTGGCT
GGAAAACTGGCTGTCCCGCTTTGCCGGGGCGGCGCTGATCGTCAGTCATGATCGCGGGTTGCTGGACCGGGCGGTGGATG
CCATCGCACATCTGGACCAACGCAAGCTGACGCTGACGCCGGGCGGATACAGCGAATTCGTGCGCATCCGCACCGAACAG
GCCCTGCAGCAGGCCCGGGCGGCGGAACGGATCGCGGCGCAGCGCGCCCACATGCAATCCTTCGTCGATCGCTTCCGCGC
CAAGGCGACCAAGGCGCGGCAGGCCCAGGCACGGCTGAAGGCGCTGGAGAAGCTGCCGGTCCTGGACACCGTGGTCGAGG
ATGCGCCCACCCGCTTCGCCTTCCCCGAACCCGCGCCCCTGCCCCCGCCGATGCTGACGCTGGACCGGGTTTCGGTCGGC
TATGGCGGCCGGCCGATCCTGTCCGGCCTGACCCTGCGGCTGGACATGGAGGATAGGATCGCCCTGCTGGGCGCCAACGG
CAACGGCAAATCGACCTTCGCCAAGCTGATCGCGGGACGGCTGGCGCCGATTTCGGGCACCGTGGCGCATGGTCCGCGCC
TGCGCGTCGGCTATTTCGCCCAGCATCAGGCGGAGGAACTGGTTCCCGGCGAAACGCCGGTCGATCACATGACCCGCGTC
ATGCCCAAGGCACCGCCCACCGCCGTGCGGGCGCAACTGGCCCGCTTCGGGCTGGATGCCGACCGCGCCGACACGGTGAC
GCGGGACCTGTCGGGCGGCGAGAAGGCGCGGCTGCTGCTGGCGCTGGCCACGCGTGAGGCACCGCACCTGCTGATCCTGG
ACGAACCGACCAACCATCTGGACCTGGACGCGCGCGAGGCCCTGATCCGCGCCCTGGCGGAATTCGAGGGGGCCGTACTG
CTGATCAGCCATGACCCGCACCTGGTCGAACTGGTCGCCGACCGGCTGTGGCTGGTGGGCGACGGCACCGTGCGGCCCTT
CGACGGCGACATGGCGGAATATCGGACATGGCTGTCCGAACGCGCCCGGGCGGCCACCCGCCCGGCCACCCCGGCGGCCC
CCCGCCGCGACGACAGGCGCGAACGCGCCGAAGCCCGCAAGGCCATCGCCCCCCTCCGCCGGAAGGCACGGGACGCCGAA
GCCCGGATGAGCCGCCTGGCCGACGAGCGCGGCCGGCTGGAAACCCGGCTGGCCGACCCCGCGCTCTATGCCGCCGGCGG
CGCCGACGAGGTCACGGCGATCAACACGCGGCTGGCCGCCATCGGGCGCGAGCAGGAAGAGGCCGAGGAGGAGTGGCTGC
TGGCCGAGGCGGCGATCGAGGAAAGCGCCGCCGAGTGA

Upstream 100 bases:

>100_bases
GTTCACGTGGCGGAGCACGACGCCCGCCACGCACGGGATTGCATAACTATCAAAGGGTTGGCCAGGCGTGCCGGCCCGTT
CTTCCGGAGCCCCGTATCCC

Downstream 100 bases:

>100_bases
GCCGACTAGTCCGCCGACGCGGTCACGGCTGCTCGGTTGGGGACGCATCCCCCAATGCGCCCGCCGCGAAAGCGAGGCTG
GAGGCGGCGATCAGGGCGGC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 625; Mature: 624

Protein sequence:

>625_residues
MSLLVISDLTLRIAGRTLLDGASLTVDPGRKIGLVGRNGAGKSTLLAAIAGDIAPDGGTIHLSSRARMARIRQEAPSGDA
NLLDTVLAGDAERTALMAEADQTPDPVRLADIHERLRAIGADSAPARAATILSGLGFDADAQARPVSDFSGGWRMRVALA
TALFLNPDLLLLDEPTNHLDLDATIWLENWLSRFAGAALIVSHDRGLLDRAVDAIAHLDQRKLTLTPGGYSEFVRIRTEQ
ALQQARAAERIAAQRAHMQSFVDRFRAKATKARQAQARLKALEKLPVLDTVVEDAPTRFAFPEPAPLPPPMLTLDRVSVG
YGGRPILSGLTLRLDMEDRIALLGANGNGKSTFAKLIAGRLAPISGTVAHGPRLRVGYFAQHQAEELVPGETPVDHMTRV
MPKAPPTAVRAQLARFGLDADRADTVTRDLSGGEKARLLLALATREAPHLLILDEPTNHLDLDAREALIRALAEFEGAVL
LISHDPHLVELVADRLWLVGDGTVRPFDGDMAEYRTWLSERARAATRPATPAAPRRDDRRERAEARKAIAPLRRKARDAE
ARMSRLADERGRLETRLADPALYAAGGADEVTAINTRLAAIGREQEEAEEEWLLAEAAIEESAAE

Sequences:

>Translated_625_residues
MSLLVISDLTLRIAGRTLLDGASLTVDPGRKIGLVGRNGAGKSTLLAAIAGDIAPDGGTIHLSSRARMARIRQEAPSGDA
NLLDTVLAGDAERTALMAEADQTPDPVRLADIHERLRAIGADSAPARAATILSGLGFDADAQARPVSDFSGGWRMRVALA
TALFLNPDLLLLDEPTNHLDLDATIWLENWLSRFAGAALIVSHDRGLLDRAVDAIAHLDQRKLTLTPGGYSEFVRIRTEQ
ALQQARAAERIAAQRAHMQSFVDRFRAKATKARQAQARLKALEKLPVLDTVVEDAPTRFAFPEPAPLPPPMLTLDRVSVG
YGGRPILSGLTLRLDMEDRIALLGANGNGKSTFAKLIAGRLAPISGTVAHGPRLRVGYFAQHQAEELVPGETPVDHMTRV
MPKAPPTAVRAQLARFGLDADRADTVTRDLSGGEKARLLLALATREAPHLLILDEPTNHLDLDAREALIRALAEFEGAVL
LISHDPHLVELVADRLWLVGDGTVRPFDGDMAEYRTWLSERARAATRPATPAAPRRDDRRERAEARKAIAPLRRKARDAE
ARMSRLADERGRLETRLADPALYAAGGADEVTAINTRLAAIGREQEEAEEEWLLAEAAIEESAAE
>Mature_624_residues
SLLVISDLTLRIAGRTLLDGASLTVDPGRKIGLVGRNGAGKSTLLAAIAGDIAPDGGTIHLSSRARMARIRQEAPSGDAN
LLDTVLAGDAERTALMAEADQTPDPVRLADIHERLRAIGADSAPARAATILSGLGFDADAQARPVSDFSGGWRMRVALAT
ALFLNPDLLLLDEPTNHLDLDATIWLENWLSRFAGAALIVSHDRGLLDRAVDAIAHLDQRKLTLTPGGYSEFVRIRTEQA
LQQARAAERIAAQRAHMQSFVDRFRAKATKARQAQARLKALEKLPVLDTVVEDAPTRFAFPEPAPLPPPMLTLDRVSVGY
GGRPILSGLTLRLDMEDRIALLGANGNGKSTFAKLIAGRLAPISGTVAHGPRLRVGYFAQHQAEELVPGETPVDHMTRVM
PKAPPTAVRAQLARFGLDADRADTVTRDLSGGEKARLLLALATREAPHLLILDEPTNHLDLDAREALIRALAEFEGAVLL
ISHDPHLVELVADRLWLVGDGTVRPFDGDMAEYRTWLSERARAATRPATPAAPRRDDRRERAEARKAIAPLRRKARDAEA
RMSRLADERGRLETRLADPALYAAGGADEVTAINTRLAAIGREQEEAEEEWLLAEAAIEESAAE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=532, Percent_Identity=40.7894736842105, Blast_Score=385, Evalue=1e-107,
Organism=Homo sapiens, GI27881506, Length=527, Percent_Identity=37.5711574952562, Blast_Score=357, Evalue=2e-98,
Organism=Homo sapiens, GI10947137, Length=527, Percent_Identity=37.5711574952562, Blast_Score=356, Evalue=3e-98,
Organism=Homo sapiens, GI10947135, Length=537, Percent_Identity=38.3612662942272, Blast_Score=296, Evalue=4e-80,
Organism=Homo sapiens, GI69354671, Length=537, Percent_Identity=38.3612662942272, Blast_Score=296, Evalue=5e-80,
Organism=Escherichia coli, GI1789751, Length=629, Percent_Identity=45.4689984101749, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI1787041, Length=523, Percent_Identity=33.8432122370937, Blast_Score=308, Evalue=7e-85,
Organism=Escherichia coli, GI1787182, Length=642, Percent_Identity=30.3738317757009, Blast_Score=248, Evalue=8e-67,
Organism=Escherichia coli, GI2367384, Length=550, Percent_Identity=30.9090909090909, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1788165, Length=184, Percent_Identity=34.2391304347826, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789891, Length=253, Percent_Identity=27.6679841897233, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787164, Length=201, Percent_Identity=31.8407960199005, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789873, Length=214, Percent_Identity=30.8411214953271, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788506, Length=215, Percent_Identity=30.2325581395349, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788761, Length=220, Percent_Identity=29.0909090909091, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1786563, Length=214, Percent_Identity=28.9719626168224, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786398, Length=219, Percent_Identity=28.7671232876712, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693107, Length=209, Percent_Identity=29.1866028708134, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789864, Length=237, Percent_Identity=25.7383966244726, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788225, Length=213, Percent_Identity=27.6995305164319, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1789586, Length=222, Percent_Identity=31.0810810810811, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1787792, Length=92, Percent_Identity=35.8695652173913, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=527, Percent_Identity=40.4174573055028, Blast_Score=366, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17559834, Length=540, Percent_Identity=37.037037037037, Blast_Score=339, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI17555318, Length=535, Percent_Identity=34.7663551401869, Blast_Score=330, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI17541710, Length=187, Percent_Identity=31.0160427807487, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17565938, Length=224, Percent_Identity=27.2321428571429, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321121, Length=542, Percent_Identity=36.1623616236162, Blast_Score=364, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320874, Length=531, Percent_Identity=32.7683615819209, Blast_Score=303, Evalue=8e-83,
Organism=Saccharomyces cerevisiae, GI6325030, Length=396, Percent_Identity=31.0606060606061, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324314, Length=380, Percent_Identity=28.9473684210526, Blast_Score=153, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6323278, Length=389, Percent_Identity=27.7634961439589, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24666836, Length=524, Percent_Identity=41.793893129771, Blast_Score=409, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24642252, Length=546, Percent_Identity=36.2637362637363, Blast_Score=355, Evalue=6e-98,
Organism=Drosophila melanogaster, GI18859989, Length=546, Percent_Identity=36.2637362637363, Blast_Score=355, Evalue=6e-98,
Organism=Drosophila melanogaster, GI24641342, Length=536, Percent_Identity=37.8731343283582, Blast_Score=346, Evalue=2e-95,
Organism=Drosophila melanogaster, GI17136662, Length=178, Percent_Identity=30.8988764044944, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24659289, Length=178, Percent_Identity=28.6516853932584, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221500365, Length=204, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007184, Length=204, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653245, Length=204, Percent_Identity=28.921568627451, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363262, Length=204, Percent_Identity=28.921568627451, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI23397593, Length=250, Percent_Identity=28.4, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 67604; Mature: 67473

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLVISDLTLRIAGRTLLDGASLTVDPGRKIGLVGRNGAGKSTLLAAIAGDIAPDGGTI
CEEEEEECCEEEECCCCEECCCCEEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCEE
HLSSRARMARIRQEAPSGDANLLDTVLAGDAERTALMAEADQTPDPVRLADIHERLRAIG
EECCHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHEEEECCCCCCCCCHHHHHHHHHHHHC
ADSAPARAATILSGLGFDADAQARPVSDFSGGWRMRVALATALFLNPDLLLLDEPTNHLD
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCCC
LDATIWLENWLSRFAGAALIVSHDRGLLDRAVDAIAHLDQRKLTLTPGGYSEFVRIRTEQ
CCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH
ALQQARAAERIAAQRAHMQSFVDRFRAKATKARQAQARLKALEKLPVLDTVVEDAPTRFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
FPEPAPLPPPMLTLDRVSVGYGGRPILSGLTLRLDMEDRIALLGANGNGKSTFAKLIAGR
CCCCCCCCCCCEEECCEECCCCCCHHHCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHH
LAPISGTVAHGPRLRVGYFAQHQAEELVPGETPVDHMTRVMPKAPPTAVRAQLARFGLDA
CCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCC
DRADTVTRDLSGGEKARLLLALATREAPHLLILDEPTNHLDLDAREALIRALAEFEGAVL
CHHHHHHHHCCCCCHHEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEE
LISHDPHLVELVADRLWLVGDGTVRPFDGDMAEYRTWLSERARAATRPATPAAPRRDDRR
EEECCCHHHHHHHHCEEEEECCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
ERAEARKAIAPLRRKARDAEARMSRLADERGRLETRLADPALYAAGGADEVTAINTRLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEECCCCCCHHHHHHHHHH
IGREQEEAEEEWLLAEAAIEESAAE
HCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLLVISDLTLRIAGRTLLDGASLTVDPGRKIGLVGRNGAGKSTLLAAIAGDIAPDGGTI
EEEEEECCEEEECCCCEECCCCEEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCEE
HLSSRARMARIRQEAPSGDANLLDTVLAGDAERTALMAEADQTPDPVRLADIHERLRAIG
EECCHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHEEEECCCCCCCCCHHHHHHHHHHHHC
ADSAPARAATILSGLGFDADAQARPVSDFSGGWRMRVALATALFLNPDLLLLDEPTNHLD
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCCC
LDATIWLENWLSRFAGAALIVSHDRGLLDRAVDAIAHLDQRKLTLTPGGYSEFVRIRTEQ
CCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH
ALQQARAAERIAAQRAHMQSFVDRFRAKATKARQAQARLKALEKLPVLDTVVEDAPTRFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
FPEPAPLPPPMLTLDRVSVGYGGRPILSGLTLRLDMEDRIALLGANGNGKSTFAKLIAGR
CCCCCCCCCCCEEECCEECCCCCCHHHCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHH
LAPISGTVAHGPRLRVGYFAQHQAEELVPGETPVDHMTRVMPKAPPTAVRAQLARFGLDA
CCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCC
DRADTVTRDLSGGEKARLLLALATREAPHLLILDEPTNHLDLDAREALIRALAEFEGAVL
CHHHHHHHHCCCCCHHEEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEE
LISHDPHLVELVADRLWLVGDGTVRPFDGDMAEYRTWLSERARAATRPATPAAPRRDDRR
EEECCCHHHHHHHHCEEEEECCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
ERAEARKAIAPLRRKARDAEARMSRLADERGRLETRLADPALYAAGGADEVTAINTRLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEECCCCCCHHHHHHHHHH
IGREQEEAEEEWLLAEAAIEESAAE
HCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]