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The map label for this gene is purQ [H]

Identifier: 162147743

GI number: 162147743

Start: 1993610

End: 1994311

Strand: Direct

Name: purQ [H]

Synonym: GDI_1959

Alternate gene names: 162147743

Gene position: 1993610-1994311 (Clockwise)

Preceding gene: 162147742

Following gene: 162147744

Centisome position: 50.55

GC content: 69.37

Gene sequence:

>702_bases
ATGAAGGCCGGCATCGTCGTCTTCCCGGGGACGAACCGGGAGAGGGACATGGCGATCGCGCTGCGCGGCGTGACCGGCCG
CGCACCGGCCATGATCTGGCATCGTGATACCGACCTGCCGGACCTGGACCTGGTGGTGCTGGCCGGCGGGTTCAGCTACG
GCGATTACCTGCGCTGCGGTGCCATGGCGGCCCACGCCCCGATCATGGCGGCCGTCCGCCGCTTCGCCGAGGCCGGGGGG
CATATCCTGGGGGTCTGCAACGGCTTCCAGATCCTGACGGAGACCGGATTGCTGCCCGGCGCGCTGCTGCGCAACGCGGC
GCTGCGCTTCCTGTCGCAGGATTGCCATCTGCGCGTCGAACGCAACGACACGCCCTTTACCCGCCGCTGGCAGGTGGGTG
ACGTGTTCCGTACCCCGATGGCGCATGGCGACGGCAACTACATCGCCGACGACGCGACGATCCACGCGCTGGAAGACGAG
GGCCGCGTGGCCTTCCGCTATGCCCGGCCCGACGGGCGGGTGGATGCGGGCGACCGGCAGACGAACCCGAACGGCAGCGT
GAACGCGATTGCCGGCGTATTCAGCGCCAACCTGCGGATCTGCGGCATGATGCCGCACCCCGAGGACCTGGTGGACCCGC
TGATGGGCGGCGAGGACGGAAAACCCCTGTTCGAGGGGCTGGTGGAGGCTCTGGTCCGATGA

Upstream 100 bases:

>100_bases
TGGTGACCTGGCTGCATGGGCATAGCGACCAGTTGTCCAAGCCGGTCGGCGAACTGGTCTTCACGGCGCTGCACGAATCC
TATCCCTGCGGTGGCGGCAA

Downstream 100 bases:

>100_bases
GCAGCGAAAAGGGACAGCGACCTGTCGATCAGGACCTGGCGAAGGAATTCGGGCTGACCGCGGAAGAATACGGCAACGTC
CTGTCGATCATGGGCCGCAC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKAGIVVFPGTNRERDMAIALRGVTGRAPAMIWHRDTDLPDLDLVVLAGGFSYGDYLRCGAMAAHAPIMAAVRRFAEAGG
HILGVCNGFQILTETGLLPGALLRNAALRFLSQDCHLRVERNDTPFTRRWQVGDVFRTPMAHGDGNYIADDATIHALEDE
GRVAFRYARPDGRVDAGDRQTNPNGSVNAIAGVFSANLRICGMMPHPEDLVDPLMGGEDGKPLFEGLVEALVR

Sequences:

>Translated_233_residues
MKAGIVVFPGTNRERDMAIALRGVTGRAPAMIWHRDTDLPDLDLVVLAGGFSYGDYLRCGAMAAHAPIMAAVRRFAEAGG
HILGVCNGFQILTETGLLPGALLRNAALRFLSQDCHLRVERNDTPFTRRWQVGDVFRTPMAHGDGNYIADDATIHALEDE
GRVAFRYARPDGRVDAGDRQTNPNGSVNAIAGVFSANLRICGMMPHPEDLVDPLMGGEDGKPLFEGLVEALVR
>Mature_233_residues
MKAGIVVFPGTNRERDMAIALRGVTGRAPAMIWHRDTDLPDLDLVVLAGGFSYGDYLRCGAMAAHAPIMAAVRRFAEAGG
HILGVCNGFQILTETGLLPGALLRNAALRFLSQDCHLRVERNDTPFTRRWQVGDVFRTPMAHGDGNYIADDATIHALEDE
GRVAFRYARPDGRVDAGDRQTNPNGSVNAIAGVFSANLRICGMMPHPEDLVDPLMGGEDGKPLFEGLVEALVR

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=204, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321498, Length=189, Percent_Identity=30.6878306878307, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25237; Mature: 25237

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAGIVVFPGTNRERDMAIALRGVTGRAPAMIWHRDTDLPDLDLVVLAGGFSYGDYLRCG
CCCCEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHH
AMAAHAPIMAAVRRFAEAGGHILGVCNGFQILTETGLLPGALLRNAALRFLSQDCHLRVE
HHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEHHCCCCCHHHHHHHHHHHHCCCCEEEEE
RNDTPFTRRWQVGDVFRTPMAHGDGNYIADDATIHALEDEGRVAFRYARPDGRVDAGDRQ
CCCCCCEEEEECCHHHHCCCCCCCCCEEECCCEEEEECCCCCEEEEEECCCCCCCCCCCC
TNPNGSVNAIAGVFSANLRICGMMPHPEDLVDPLMGGEDGKPLFEGLVEALVR
CCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKAGIVVFPGTNRERDMAIALRGVTGRAPAMIWHRDTDLPDLDLVVLAGGFSYGDYLRCG
CCCCEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHH
AMAAHAPIMAAVRRFAEAGGHILGVCNGFQILTETGLLPGALLRNAALRFLSQDCHLRVE
HHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEHHCCCCCHHHHHHHHHHHHCCCCEEEEE
RNDTPFTRRWQVGDVFRTPMAHGDGNYIADDATIHALEDEGRVAFRYARPDGRVDAGDRQ
CCCCCCEEEEECCHHHHCCCCCCCCCEEECCCEEEEECCCCCEEEEEECCCCCCCCCCCC
TNPNGSVNAIAGVFSANLRICGMMPHPEDLVDPLMGGEDGKPLFEGLVEALVR
CCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA