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The map label for this gene is trpD [H]

Identifier: 162147720

GI number: 162147720

Start: 1970921

End: 1972051

Strand: Direct

Name: trpD [H]

Synonym: GDI_1936

Alternate gene names: 162147720

Gene position: 1970921-1972051 (Clockwise)

Preceding gene: 162147719

Following gene: 162147721

Centisome position: 49.97

GC content: 69.32

Gene sequence:

>1131_bases
ATGGATGGCGTGCCGTCCCTGTCTGCCGACCAAGCGGGTGCGTTCCGGACCATCCTGAACCGCCTGGCGCGGGGCGAAAC
ACTGACTGAAACCGAGGCCGAGGACGCGTTCGGCCTGATCATGGACGGCGGCGTGCCCGACACGCTGATCGCCGCCTTCC
TGATGGCGTTGCGGGTCCGGGGTGAGAAGCGCGCGGAACTGCTGGGCGCGGTGCGCGCCGTGCGGTCACGCATGCGGGCG
GTCGGCCCCGTTCCTCCGGGCACGATCGATGTCTGCGGCACGGGCGGCGACGGACTGGGCACACTGAATATTTCGACCGC
CGTCGCCTTCGTCCTGGCCGCGCTGGGTGTTCCGGTCGCCAAGCATGGCAACCGGGCCCTGTCGTCGCGTTCCGGCGCGA
CCGACGTGCTGGGCGCGCTGGGCGTGGATCTGTCGGACGACCCGTCGGTGATCGCCGCGCGGATCAATGACGGAAACCTG
GCTTTCATGGCGGCGCCGGCGCACCATCCGGCCATGCGCCATGCCGGACCGGTGCGGGCCGCGCTGGGAATCCGCACGCT
GTTCAACCTGATCGGCCCCTTGTGCAATCCGGCCGGCGTCACACATCAACTGGTCGGTGTGTTCGATCCGGCATGGCTGC
GCCCGGTGGTGGAGACGTTGCAGCTTCTGGGGTCGGAGCGCGTGTGGGCCGTGCATGGCTATTGCGAAGGCGCGACGGGC
GGCCGGGGCGTGGACGAACTGACGCTGGCCGGTCCTACCGCGATCGTGGCGTTGCAGAACGGACGGATTTACGACCTGAC
GCTGCGGCCCGAGGATGCGGGCCTGCGCCCCGCGCCGATCACGGCGATCGCGGGTGGCGGGGCGGAGGAAAATGCGGCGG
CCCTTACGGCTTTGCTGGCGGGCGCCCATGGAGCCTATCGCGATACCGTGCTGCTGAACGCGGCGGCCTGCCTGCATGTG
GCGGGACGCGGTGCGGCACTGGATGACGATGGGAGATTGAGACCGGCGTCGCTACGGGCGCTGGTGGCGGATGCGGCCCG
CGTGCTGGATGACGGATCGGCCCTGGCCATGCTGAATTCCGCGCGCCGTCGCCACATGGATACGCCGGAGGGGATTACAC
AAAGCTTATGA

Upstream 100 bases:

>100_bases
CCCGAGAGCATCGCGTCGGAACACGGGCACGACATCCTGGCCAATTTCATGGCCATCGCGCGGGGCCTGAACACACCGCG
AAAAGCGGCCTGAGCCGATC

Downstream 100 bases:

>100_bases
TGAACGACATGCCGACAAGCCAGGCGCCGATCGATTGCGGTAACACGCCCGGCCAGGACGGGATTCCCGATGTCCTGGCG
CGGATTTGTGCCCGCACCCG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MDGVPSLSADQAGAFRTILNRLARGETLTETEAEDAFGLIMDGGVPDTLIAAFLMALRVRGEKRAELLGAVRAVRSRMRA
VGPVPPGTIDVCGTGGDGLGTLNISTAVAFVLAALGVPVAKHGNRALSSRSGATDVLGALGVDLSDDPSVIAARINDGNL
AFMAAPAHHPAMRHAGPVRAALGIRTLFNLIGPLCNPAGVTHQLVGVFDPAWLRPVVETLQLLGSERVWAVHGYCEGATG
GRGVDELTLAGPTAIVALQNGRIYDLTLRPEDAGLRPAPITAIAGGGAEENAAALTALLAGAHGAYRDTVLLNAAACLHV
AGRGAALDDDGRLRPASLRALVADAARVLDDGSALAMLNSARRRHMDTPEGITQSL

Sequences:

>Translated_376_residues
MDGVPSLSADQAGAFRTILNRLARGETLTETEAEDAFGLIMDGGVPDTLIAAFLMALRVRGEKRAELLGAVRAVRSRMRA
VGPVPPGTIDVCGTGGDGLGTLNISTAVAFVLAALGVPVAKHGNRALSSRSGATDVLGALGVDLSDDPSVIAARINDGNL
AFMAAPAHHPAMRHAGPVRAALGIRTLFNLIGPLCNPAGVTHQLVGVFDPAWLRPVVETLQLLGSERVWAVHGYCEGATG
GRGVDELTLAGPTAIVALQNGRIYDLTLRPEDAGLRPAPITAIAGGGAEENAAALTALLAGAHGAYRDTVLLNAAACLHV
AGRGAALDDDGRLRPASLRALVADAARVLDDGSALAMLNSARRRHMDTPEGITQSL
>Mature_376_residues
MDGVPSLSADQAGAFRTILNRLARGETLTETEAEDAFGLIMDGGVPDTLIAAFLMALRVRGEKRAELLGAVRAVRSRMRA
VGPVPPGTIDVCGTGGDGLGTLNISTAVAFVLAALGVPVAKHGNRALSSRSGATDVLGALGVDLSDDPSVIAARINDGNL
AFMAAPAHHPAMRHAGPVRAALGIRTLFNLIGPLCNPAGVTHQLVGVFDPAWLRPVVETLQLLGSERVWAVHGYCEGATG
GRGVDELTLAGPTAIVALQNGRIYDLTLRPEDAGLRPAPITAIAGGGAEENAAALTALLAGAHGAYRDTVLLNAAACLHV
AGRGAALDDDGRLRPASLRALVADAARVLDDGSALAMLNSARRRHMDTPEGITQSL

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=295, Percent_Identity=39.6610169491525, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1787019, Length=227, Percent_Identity=24.2290748898678, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320561, Length=347, Percent_Identity=29.971181556196, Blast_Score=116, Evalue=6e-27,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 38564; Mature: 38564

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGVPSLSADQAGAFRTILNRLARGETLTETEAEDAFGLIMDGGVPDTLIAAFLMALRVR
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
GEKRAELLGAVRAVRSRMRAVGPVPPGTIDVCGTGGDGLGTLNISTAVAFVLAALGVPVA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHCCCHH
KHGNRALSSRSGATDVLGALGVDLSDDPSVIAARINDGNLAFMAAPAHHPAMRHAGPVRA
HCCCHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHCCCHHHH
ALGIRTLFNLIGPLCNPAGVTHQLVGVFDPAWLRPVVETLQLLGSERVWAVHGYCEGATG
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
GRGVDELTLAGPTAIVALQNGRIYDLTLRPEDAGLRPAPITAIAGGGAEENAAALTALLA
CCCCCCEEECCCEEEEEEECCEEEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
GAHGAYRDTVLLNAAACLHVAGRGAALDDDGRLRPASLRALVADAARVLDDGSALAMLNS
CCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
ARRRHMDTPEGITQSL
HHHHCCCCCCHHHHCC
>Mature Secondary Structure
MDGVPSLSADQAGAFRTILNRLARGETLTETEAEDAFGLIMDGGVPDTLIAAFLMALRVR
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
GEKRAELLGAVRAVRSRMRAVGPVPPGTIDVCGTGGDGLGTLNISTAVAFVLAALGVPVA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEHHHHHHHHHHHHCCCHH
KHGNRALSSRSGATDVLGALGVDLSDDPSVIAARINDGNLAFMAAPAHHPAMRHAGPVRA
HCCCHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHCCCHHHH
ALGIRTLFNLIGPLCNPAGVTHQLVGVFDPAWLRPVVETLQLLGSERVWAVHGYCEGATG
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
GRGVDELTLAGPTAIVALQNGRIYDLTLRPEDAGLRPAPITAIAGGGAEENAAALTALLA
CCCCCCEEECCCEEEEEEECCEEEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
GAHGAYRDTVLLNAAACLHVAGRGAALDDDGRLRPASLRALVADAARVLDDGSALAMLNS
CCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
ARRRHMDTPEGITQSL
HHHHCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA