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The map label for this gene is thiO [H]

Identifier: 162147563

GI number: 162147563

Start: 1809575

End: 1810657

Strand: Direct

Name: thiO [H]

Synonym: GDI_1779

Alternate gene names: 162147563

Gene position: 1809575-1810657 (Clockwise)

Preceding gene: 162147562

Following gene: 162147564

Centisome position: 45.88

GC content: 71.1

Gene sequence:

>1083_bases
ATGGGGATGAGAGCAAGGTCGGCGCGCGACGCGCCGATGAACTTGCCACGGGAAGGAGCGACGACCATGGAACAGGCTGA
ATCCGGCGCGCGGTTGCGGGTTCTGGTGCGTGGGGCCGGGGTGGCCGGCCTGACCAGCGCCGTGACGCTGGCCGAGCGGG
GGGCGGATGTCACCCTGCTGGAAGTCAGCGCGGAACTGGGCGCGGGGGCTGCGTCATGGATGGCCGGCGGCATGCTCGCC
CCGTGGTGCGAGGCCGAATCCGCCCCGCCCGAGGTCACGCGCGATTCGCTGGAATCGGTCGATTGGTGGGCGTCGCATGT
GCCCGGGGTCGTGCGCAACGGCACCCTGGTCCTGGCCCCGCCGCGTGACGAGGGCGACATCGCGCGGTTCGGCCGGCGGA
CCAGCCATTTCGACCTGGTGGACGCCGCCCGCATCGCCGAATTGGAGCCCGACCTGGACGGGCGATTCAACAAGGGCCTG
TTCTTCCCCGCCGAGGGCCATGTCGATCCGCGCCTGGCCCTCGCCGCGCTGCGCGACCGGCTGGTCGCGCTGGGCGGCAC
GGTGCGGATGAACGCCCCGGCCGGGGACGTGCCCGCCGACCTTGCCGCCGGCGGGTTCGACCGGGTGGTGGACTGCACCG
GCGTCGCGGCGCGACCCCACCTCAAGGGGCTGCGGGCCATGCGGGGGGAAATGCTGCTGCTGCGCTGCCCCGACGTGACG
CTGCATCGTCCCGTGCGCATGCTTCATCCGCGCATTCCGGTTTACATTGTGCCGCGTGCCGACCATCTGTTCATGGTCGG
GGCCACGATGGTGGAAAGCGAAAATGCCGGGGGCATGACCCTTCGCTCGATGGTGGAGCTGCTGACCGCCGCCTACGTGC
TGCATCCCGCGTTCGGCGAGGCGGAGATCGTCGAAACCGGGGTGGGGTTGCGGCCGGCCTATCCCGACAACGTGCCCGCC
GTCACCGTCCAGGGCCGGACGGTCTATGTGAACGGGATGTACCGGCACGGTTTCCTGCTGTCGCCGTCACGGGCGCGGCA
GGCCGCGGATATCGTGTTCGGCACGGCCGAGGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
AACGCTCTGGAATAGCGGTCCCGGGGGCTTTTCCCGCATCCGCTGTTGTCATCCGCCGCGCGAGGAAACATCCTCCGCAC
GACCCGCGAGTGAGGACTCG

Downstream 100 bases:

>100_bases
ACCAAAGGGTCAAGGAGGGAAGATGAGGATTCTGGTAAACGAGGAGCCGCGCGAGGTCTCCACCGCGACCCTGGCCGCCC
TGCTCGACGAACTGGGATAT

Product: thiamine biosynthesis oxidoreductase thiO

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MGMRARSARDAPMNLPREGATTMEQAESGARLRVLVRGAGVAGLTSAVTLAERGADVTLLEVSAELGAGAASWMAGGMLA
PWCEAESAPPEVTRDSLESVDWWASHVPGVVRNGTLVLAPPRDEGDIARFGRRTSHFDLVDAARIAELEPDLDGRFNKGL
FFPAEGHVDPRLALAALRDRLVALGGTVRMNAPAGDVPADLAAGGFDRVVDCTGVAARPHLKGLRAMRGEMLLLRCPDVT
LHRPVRMLHPRIPVYIVPRADHLFMVGATMVESENAGGMTLRSMVELLTAAYVLHPAFGEAEIVETGVGLRPAYPDNVPA
VTVQGRTVYVNGMYRHGFLLSPSRARQAADIVFGTAEAAA

Sequences:

>Translated_360_residues
MGMRARSARDAPMNLPREGATTMEQAESGARLRVLVRGAGVAGLTSAVTLAERGADVTLLEVSAELGAGAASWMAGGMLA
PWCEAESAPPEVTRDSLESVDWWASHVPGVVRNGTLVLAPPRDEGDIARFGRRTSHFDLVDAARIAELEPDLDGRFNKGL
FFPAEGHVDPRLALAALRDRLVALGGTVRMNAPAGDVPADLAAGGFDRVVDCTGVAARPHLKGLRAMRGEMLLLRCPDVT
LHRPVRMLHPRIPVYIVPRADHLFMVGATMVESENAGGMTLRSMVELLTAAYVLHPAFGEAEIVETGVGLRPAYPDNVPA
VTVQGRTVYVNGMYRHGFLLSPSRARQAADIVFGTAEAAA
>Mature_359_residues
GMRARSARDAPMNLPREGATTMEQAESGARLRVLVRGAGVAGLTSAVTLAERGADVTLLEVSAELGAGAASWMAGGMLAP
WCEAESAPPEVTRDSLESVDWWASHVPGVVRNGTLVLAPPRDEGDIARFGRRTSHFDLVDAARIAELEPDLDGRFNKGLF
FPAEGHVDPRLALAALRDRLVALGGTVRMNAPAGDVPADLAAGGFDRVVDCTGVAARPHLKGLRAMRGEMLLLRCPDVTL
HRPVRMLHPRIPVYIVPRADHLFMVGATMVESENAGGMTLRSMVELLTAAYVLHPAFGEAEIVETGVGLRPAYPDNVPAV
TVQGRTVYVNGMYRHGFLLSPSRARQAADIVFGTAEAAA

Specific function: May have amino acid oxidase activity in the biosynthesis of thiazole when cysteine gives its thiol group to be inserted into the thiazole molecule and the rest of the molecule is deaminated to give pyruvic acid and ammonia [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: NA

Molecular weight: Translated: 38307; Mature: 38176

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMRARSARDAPMNLPREGATTMEQAESGARLRVLVRGAGVAGLTSAVTLAERGADVTLL
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
EVSAELGAGAASWMAGGMLAPWCEAESAPPEVTRDSLESVDWWASHVPGVVRNGTLVLAP
EEEHHHCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
PRDEGDIARFGRRTSHFDLVDAARIAELEPDLDGRFNKGLFFPAEGHVDPRLALAALRDR
CCCCCHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHH
LVALGGTVRMNAPAGDVPADLAAGGFDRVVDCTGVAARPHLKGLRAMRGEMLLLRCPDVT
HHHCCCEEEECCCCCCCCHHHHCCCCHHEEECCCCCCCCHHHHHHHHCCCEEEEECCCCH
LHRPVRMLHPRIPVYIVPRADHLFMVGATMVESENAGGMTLRSMVELLTAAYVLHPAFGE
HHCCHHHHCCCCCEEEEECCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC
AEIVETGVGLRPAYPDNVPAVTVQGRTVYVNGMYRHGFLLSPSRARQAADIVFGTAEAAA
CHHHHCCCCCCCCCCCCCCEEEECCCEEEEEEEEECCEEECCHHHHHHHHEEEECHHCCC
>Mature Secondary Structure 
GMRARSARDAPMNLPREGATTMEQAESGARLRVLVRGAGVAGLTSAVTLAERGADVTLL
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
EVSAELGAGAASWMAGGMLAPWCEAESAPPEVTRDSLESVDWWASHVPGVVRNGTLVLAP
EEEHHHCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
PRDEGDIARFGRRTSHFDLVDAARIAELEPDLDGRFNKGLFFPAEGHVDPRLALAALRDR
CCCCCHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHH
LVALGGTVRMNAPAGDVPADLAAGGFDRVVDCTGVAARPHLKGLRAMRGEMLLLRCPDVT
HHHCCCEEEECCCCCCCCHHHHCCCCHHEEECCCCCCCCHHHHHHHHCCCEEEEECCCCH
LHRPVRMLHPRIPVYIVPRADHLFMVGATMVESENAGGMTLRSMVELLTAAYVLHPAFGE
HHCCHHHHCCCCCEEEEECCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC
AEIVETGVGLRPAYPDNVPAVTVQGRTVYVNGMYRHGFLLSPSRARQAADIVFGTAEAAA
CHHHHCCCCCCCCCCCCCCEEEECCCEEEEEEEEECCEEECCHHHHHHHHEEEECHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371431 [H]