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The map label for this gene is glmS [H]

Identifier: 162147562

GI number: 162147562

Start: 1807653

End: 1809476

Strand: Direct

Name: glmS [H]

Synonym: GDI_1778

Alternate gene names: 162147562

Gene position: 1807653-1809476 (Clockwise)

Preceding gene: 162147561

Following gene: 162147563

Centisome position: 45.83

GC content: 69.3

Gene sequence:

>1824_bases
ATGTGCGGCATTGTCGGCGTCGTCGGGTGCAAGTGTGCGACCCCGGTCATCTTCGACGCCCTGCGGCGGCTGGAATATCG
CGGCTATGATTCCGCCGGGATCGCGACCCTGGTCGACGGCCGGATCGAACGACGCCGCGCGGCGGGCAAGCTGGACAACC
TGGCGGCGCTGCTGGAGCGCGAGCCGCTGGCCGGCGTGACCGGAATCGGCCACACCCGCTGGGCGACCCACGGCGCGCCG
ACCGAGAACAATGCCCACCCCCACGGCACCGAACGCGTCTCGGTGGTCCATAACGGCATCATCGAGAATTTCGAGGAATT
GCGGCGCGAGCTGGAGCAGGCCGGTCACGTCTTCACGACCGAGACCGACAGCGAAACCGTCGCCCAGTTGGTCGATTTCC
ACCTGGCGCGGGGCCTGTCGCCGCGCGACGCGGCCTTCGCGGCGCTGCGCCGGCTGGAGGGCGCCTATGCGCTGGCGATG
CTGTTCGCGGGTCATGACGGGCTGGTCATTGGCGCGCGGCACGGCGCGCCGCTGGTCGTGGGCTATGGCGAGCAGGAGAT
GTTCCTGGGATCGGACAGCCTGGCCCTGGCCCCGCTGACGCGGCGCATCGCCTACCTGGATGACGGGGACTGGGTGGTCG
TGACGCGGGACGGCGCCGAATTCTTCGATGCCTCCGGCGAACGGGTGGAACGCGCCGTGCGCACCACCGCGCTGATCGCG
GGTTCGGTCGGCAAGGACGGCTATCGCCACTACATGGAAAAGGAACTGCACGAACATCCGGTGGTGATCGGCCAGACCCT
GCAGCGGCTGATCGACCCCGCCACGCGGCGGGTCGTGCTGCCCGACCTGCCGTTCGACCTGGCCAGCGTGCCGCGCGCCG
TGGTCACGGCATGCGGGTCGGCCTTCTATGCCGGCATGATCGGCCGTTACTGGCTGGAAGGCATTGCCCGCCTGCCGGTC
GATATCGATGTGGCCAGCGAGATGCGCTATCGCGATCCGCCGCTGACGCCGGGCGGGCTGGGCCTGCTGATCTCGCAATC
CGGCGAGACGGCGGACACGCTGGCCGCCTTGCGCGGCATGCGTGCCCGCCAGCAGCACATCGTGTCGGTCCTGAATGTCG
AGCAGAGCACGATAGCCCGCGAAAGCGACGTCGTGCTGGGTACGGTCGCCGGCCCCGAGATCTCGGTGGCCAGCACCAAG
GCGTTCACCGCGCAATTGTCGGTCCTGGCCTGCCTGGCCATCGCGGCGGGCCGCCTGCGGGGCACGGTGTCGGCCGAGCG
CGAGCAGGAGATGGTGGCGGCCCTGCTGGACCTGCCCAGCCGGGCGAGCGAGGTGTTCGACCAGGCCCCGGCGATCCGCG
AGATGGCGGCGGTCGTGGCGAACGCGCGCGACGTGCTGTATCTGGGGCGCGGATCGTCCTTCCCCGTCGCGCTGGAAGGC
GCGCTGAAGCTGAAGGAAGTGTCCTATATCCACGCCGAGGCCTATGCCGCCGGCGAGATGAAACACGGACCGATCTCGCT
GATCGACCAGACGGTGCCGATCGTGGCCACCGTGCCGTCCGGCCCCCTGTTCGAGAAGACGGTGTCGAACCTGCAGGAAG
CCCGCGCCCGTGGCGGCCGCCTGCTGGTCTTCACCGACACGAAGGGCGCCGAGCGCCTGCGGGGGCTGGCGGAAATCGTG
GTCGCGATCCCGACGGTCGATGAATTCACGTCCCCCGTGCTGCAGACCATCCCGGTGCAGATGCTGGCGTACGAGGTTGC
GCTGCTGAAGGGCACGGACGTGGACCAGCCCCGCAACCTGGCCAAGTCCGTCACCGTCGAATAA

Upstream 100 bases:

>100_bases
TGCCCGACGCCATGGCGCTGGGCCGGGCCCGGCAGACGAACAAGGACGGACGCGGGGCCAGCTTGCAGGCGGCGCTGCGC
AGGAAGAAGGAACAGGGCTG

Downstream 100 bases:

>100_bases
CGCTCTGGAATAGCGGTCCCGGGGGCTTTTCCCGCATCCGCTGTTGTCATCCGCCGCGCGAGGAAACATCCTCCGCACGA
CCCGCGAGTGAGGACTCGAT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MCGIVGVVGCKCATPVIFDALRRLEYRGYDSAGIATLVDGRIERRRAAGKLDNLAALLEREPLAGVTGIGHTRWATHGAP
TENNAHPHGTERVSVVHNGIIENFEELRRELEQAGHVFTTETDSETVAQLVDFHLARGLSPRDAAFAALRRLEGAYALAM
LFAGHDGLVIGARHGAPLVVGYGEQEMFLGSDSLALAPLTRRIAYLDDGDWVVVTRDGAEFFDASGERVERAVRTTALIA
GSVGKDGYRHYMEKELHEHPVVIGQTLQRLIDPATRRVVLPDLPFDLASVPRAVVTACGSAFYAGMIGRYWLEGIARLPV
DIDVASEMRYRDPPLTPGGLGLLISQSGETADTLAALRGMRARQQHIVSVLNVEQSTIARESDVVLGTVAGPEISVASTK
AFTAQLSVLACLAIAAGRLRGTVSAEREQEMVAALLDLPSRASEVFDQAPAIREMAAVVANARDVLYLGRGSSFPVALEG
ALKLKEVSYIHAEAYAAGEMKHGPISLIDQTVPIVATVPSGPLFEKTVSNLQEARARGGRLLVFTDTKGAERLRGLAEIV
VAIPTVDEFTSPVLQTIPVQMLAYEVALLKGTDVDQPRNLAKSVTVE

Sequences:

>Translated_607_residues
MCGIVGVVGCKCATPVIFDALRRLEYRGYDSAGIATLVDGRIERRRAAGKLDNLAALLEREPLAGVTGIGHTRWATHGAP
TENNAHPHGTERVSVVHNGIIENFEELRRELEQAGHVFTTETDSETVAQLVDFHLARGLSPRDAAFAALRRLEGAYALAM
LFAGHDGLVIGARHGAPLVVGYGEQEMFLGSDSLALAPLTRRIAYLDDGDWVVVTRDGAEFFDASGERVERAVRTTALIA
GSVGKDGYRHYMEKELHEHPVVIGQTLQRLIDPATRRVVLPDLPFDLASVPRAVVTACGSAFYAGMIGRYWLEGIARLPV
DIDVASEMRYRDPPLTPGGLGLLISQSGETADTLAALRGMRARQQHIVSVLNVEQSTIARESDVVLGTVAGPEISVASTK
AFTAQLSVLACLAIAAGRLRGTVSAEREQEMVAALLDLPSRASEVFDQAPAIREMAAVVANARDVLYLGRGSSFPVALEG
ALKLKEVSYIHAEAYAAGEMKHGPISLIDQTVPIVATVPSGPLFEKTVSNLQEARARGGRLLVFTDTKGAERLRGLAEIV
VAIPTVDEFTSPVLQTIPVQMLAYEVALLKGTDVDQPRNLAKSVTVE
>Mature_607_residues
MCGIVGVVGCKCATPVIFDALRRLEYRGYDSAGIATLVDGRIERRRAAGKLDNLAALLEREPLAGVTGIGHTRWATHGAP
TENNAHPHGTERVSVVHNGIIENFEELRRELEQAGHVFTTETDSETVAQLVDFHLARGLSPRDAAFAALRRLEGAYALAM
LFAGHDGLVIGARHGAPLVVGYGEQEMFLGSDSLALAPLTRRIAYLDDGDWVVVTRDGAEFFDASGERVERAVRTTALIA
GSVGKDGYRHYMEKELHEHPVVIGQTLQRLIDPATRRVVLPDLPFDLASVPRAVVTACGSAFYAGMIGRYWLEGIARLPV
DIDVASEMRYRDPPLTPGGLGLLISQSGETADTLAALRGMRARQQHIVSVLNVEQSTIARESDVVLGTVAGPEISVASTK
AFTAQLSVLACLAIAAGRLRGTVSAEREQEMVAALLDLPSRASEVFDQAPAIREMAAVVANARDVLYLGRGSSFPVALEG
ALKLKEVSYIHAEAYAAGEMKHGPISLIDQTVPIVATVPSGPLFEKTVSNLQEARARGGRLLVFTDTKGAERLRGLAEIV
VAIPTVDEFTSPVLQTIPVQMLAYEVALLKGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=692, Percent_Identity=33.2369942196532, Blast_Score=358, Evalue=1e-98,
Organism=Homo sapiens, GI205277386, Length=687, Percent_Identity=32.1688500727802, Blast_Score=348, Evalue=9e-96,
Organism=Escherichia coli, GI1790167, Length=612, Percent_Identity=46.7320261437908, Blast_Score=542, Evalue=1e-155,
Organism=Escherichia coli, GI1788651, Length=243, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17532899, Length=433, Percent_Identity=35.796766743649, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17532897, Length=433, Percent_Identity=35.796766743649, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17539970, Length=433, Percent_Identity=35.3348729792148, Blast_Score=252, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6322745, Length=433, Percent_Identity=33.7182448036951, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6323731, Length=430, Percent_Identity=29.3023255813954, Blast_Score=178, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6323730, Length=215, Percent_Identity=33.4883720930233, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323958, Length=213, Percent_Identity=30.9859154929577, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357745, Length=688, Percent_Identity=33.1395348837209, Blast_Score=345, Evalue=7e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65164; Mature: 65164

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGVVGCKCATPVIFDALRRLEYRGYDSAGIATLVDGRIERRRAAGKLDNLAALLER
CCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHC
EPLAGVTGIGHTRWATHGAPTENNAHPHGTERVSVVHNGIIENFEELRRELEQAGHVFTT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ETDSETVAQLVDFHLARGLSPRDAAFAALRRLEGAYALAMLFAGHDGLVIGARHGAPLVV
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEE
GYGEQEMFLGSDSLALAPLTRRIAYLDDGDWVVVTRDGAEFFDASGERVERAVRTTALIA
ECCCCEEEECCCCCCHHHHHHHEEEEECCCEEEEECCCHHHHCCCHHHHHHHHHHHHHHC
GSVGKDGYRHYMEKELHEHPVVIGQTLQRLIDPATRRVVLPDLPFDLASVPRAVVTACGS
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHCEEECCCCCCCHHHHHHHHHHHHHH
AFYAGMIGRYWLEGIARLPVDIDVASEMRYRDPPLTPGGLGLLISQSGETADTLAALRGM
HHHHHHHHHHHHHHHHHCCCEEECHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
RARQQHIVSVLNVEQSTIARESDVVLGTVAGPEISVASTKAFTAQLSVLACLAIAAGRLR
HHHHHHHHHHHHCHHHHHCCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
GTVSAEREQEMVAALLDLPSRASEVFDQAPAIREMAAVVANARDVLYLGRGSSFPVALEG
CCCCHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHCCCCEEEECCCCCCCEEECC
ALKLKEVSYIHAEAYAAGEMKHGPISLIDQTVPIVATVPSGPLFEKTVSNLQEARARGGR
CCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCE
LLVFTDTKGAERLRGLAEIVVAIPTVDEFTSPVLQTIPVQMLAYEVALLKGTDVDQPRNL
EEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
AKSVTVE
HHHCCCC
>Mature Secondary Structure
MCGIVGVVGCKCATPVIFDALRRLEYRGYDSAGIATLVDGRIERRRAAGKLDNLAALLER
CCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHC
EPLAGVTGIGHTRWATHGAPTENNAHPHGTERVSVVHNGIIENFEELRRELEQAGHVFTT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ETDSETVAQLVDFHLARGLSPRDAAFAALRRLEGAYALAMLFAGHDGLVIGARHGAPLVV
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEE
GYGEQEMFLGSDSLALAPLTRRIAYLDDGDWVVVTRDGAEFFDASGERVERAVRTTALIA
ECCCCEEEECCCCCCHHHHHHHEEEEECCCEEEEECCCHHHHCCCHHHHHHHHHHHHHHC
GSVGKDGYRHYMEKELHEHPVVIGQTLQRLIDPATRRVVLPDLPFDLASVPRAVVTACGS
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHCEEECCCCCCCHHHHHHHHHHHHHH
AFYAGMIGRYWLEGIARLPVDIDVASEMRYRDPPLTPGGLGLLISQSGETADTLAALRGM
HHHHHHHHHHHHHHHHHCCCEEECHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
RARQQHIVSVLNVEQSTIARESDVVLGTVAGPEISVASTKAFTAQLSVLACLAIAAGRLR
HHHHHHHHHHHHCHHHHHCCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
GTVSAEREQEMVAALLDLPSRASEVFDQAPAIREMAAVVANARDVLYLGRGSSFPVALEG
CCCCHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHCCCCEEEECCCCCCCEEECC
ALKLKEVSYIHAEAYAAGEMKHGPISLIDQTVPIVATVPSGPLFEKTVSNLQEARARGGR
CCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCE
LLVFTDTKGAERLRGLAEIVVAIPTVDEFTSPVLQTIPVQMLAYEVALLKGTDVDQPRNL
EEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
AKSVTVE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA