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The map label for this gene is gpH [H]

Identifier: 162147560

GI number: 162147560

Start: 1805456

End: 1806220

Strand: Reverse

Name: gpH [H]

Synonym: GDI_1776

Alternate gene names: 162147560

Gene position: 1806220-1805456 (Counterclockwise)

Preceding gene: 162147567

Following gene: 162147552

Centisome position: 45.79

GC content: 69.15

Gene sequence:

>765_bases
ATGCATGAGCATCACTTAGGTTTACGAAATACTGCGATCGATCGCATCGCCCATCCCGCCGACCGCCATCTTGCAGGAGA
CGTCATGCCCGCCACCCCCACGCCCCGCATCGCCGTGTTCGACATGGACGGCACCCTGCTGGACAGCCTGCCGGACCTGG
CGGCCAGCGCCGACCGGCTGCTGACCGGGTATGGCCTGCCCGGGATTTCGCCCGACCTGGTTCGCGGCATGGTGGGGGAC
GGCGTGGCGGCCCTGGTGCGCCGCCTTCTGGCCCACGCCGGCACGCCTGCGGCGGGAATCGACGTGCAGCAGGCCGTGGA
CCGCTACATGGCGGACTACACGCCGCGCGCGACCGAACAGTCGCGACCGTTCCCCGGCACCGAATATGCCCTGAAGACGC
TGCGGGACGCGGGCTGGACCCTGGCCATCTGCACCAACAAGCCGGTGGCGGCGGCGCGGCGCATCGTCAGTGAACTGGGA
CTGACGGAATGGTTCGACGCCATCGGCGGCGGCGATTCCTTCCCGGTCCGCAAGCCGGACCCCGCCCACCTGCTGGGCAC
GATCGGGCTGGCCCATGGCCATGCCGACCGCGCGATCATGGTGGGCGACCATCACAACGACATCTTCGCGGCCAAGGGCG
CCCACGTGCGCTCGGTCTTCGCCCGGTGGGGCTACGGCCGTCCGGACATGGAAGCCGGCGCCACGATCGGCGCCGATTCG
ATGACCGAAATCCCCCACATCGCCGGCCAGCTTATCCCTGCATGA

Upstream 100 bases:

>100_bases
GGACGATGGGCGGGCAGGTCAGCGGGCGCCGCGGACGGGACGGTGGCATTCATGGCATGCGGGTAGCGGGCGGGCATCGG
ACCTGTCAAACCTTGGCGCA

Downstream 100 bases:

>100_bases
CGATGGCCAGCCGTCCGAACTTCGGATGGTCGAACAGGACGCGCACGATCGTCAGCCCGTCGCCGGGCACATCCTGAAAC
CAGACCTTGCCCTGGATCGT

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MHEHHLGLRNTAIDRIAHPADRHLAGDVMPATPTPRIAVFDMDGTLLDSLPDLAASADRLLTGYGLPGISPDLVRGMVGD
GVAALVRRLLAHAGTPAAGIDVQQAVDRYMADYTPRATEQSRPFPGTEYALKTLRDAGWTLAICTNKPVAAARRIVSELG
LTEWFDAIGGGDSFPVRKPDPAHLLGTIGLAHGHADRAIMVGDHHNDIFAAKGAHVRSVFARWGYGRPDMEAGATIGADS
MTEIPHIAGQLIPA

Sequences:

>Translated_254_residues
MHEHHLGLRNTAIDRIAHPADRHLAGDVMPATPTPRIAVFDMDGTLLDSLPDLAASADRLLTGYGLPGISPDLVRGMVGD
GVAALVRRLLAHAGTPAAGIDVQQAVDRYMADYTPRATEQSRPFPGTEYALKTLRDAGWTLAICTNKPVAAARRIVSELG
LTEWFDAIGGGDSFPVRKPDPAHLLGTIGLAHGHADRAIMVGDHHNDIFAAKGAHVRSVFARWGYGRPDMEAGATIGADS
MTEIPHIAGQLIPA
>Mature_254_residues
MHEHHLGLRNTAIDRIAHPADRHLAGDVMPATPTPRIAVFDMDGTLLDSLPDLAASADRLLTGYGLPGISPDLVRGMVGD
GVAALVRRLLAHAGTPAAGIDVQQAVDRYMADYTPRATEQSRPFPGTEYALKTLRDAGWTLAICTNKPVAAARRIVSELG
LTEWFDAIGGGDSFPVRKPDPAHLLGTIGLAHGHADRAIMVGDHHNDIFAAKGAHVRSVFARWGYGRPDMEAGATIGADS
MTEIPHIAGQLIPA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=211, Percent_Identity=31.7535545023697, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 26974; Mature: 26974

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEHHLGLRNTAIDRIAHPADRHLAGDVMPATPTPRIAVFDMDGTLLDSLPDLAASADRL
CCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
LTGYGLPGISPDLVRGMVGDGVAALVRRLLAHAGTPAAGIDVQQAVDRYMADYTPRATEQ
HHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCC
SRPFPGTEYALKTLRDAGWTLAICTNKPVAAARRIVSELGLTEWFDAIGGGDSFPVRKPD
CCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCC
PAHLLGTIGLAHGHADRAIMVGDHHNDIFAAKGAHVRSVFARWGYGRPDMEAGATIGADS
HHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCEECCCH
MTEIPHIAGQLIPA
HHHHHHHHHHCCCC
>Mature Secondary Structure
MHEHHLGLRNTAIDRIAHPADRHLAGDVMPATPTPRIAVFDMDGTLLDSLPDLAASADRL
CCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
LTGYGLPGISPDLVRGMVGDGVAALVRRLLAHAGTPAAGIDVQQAVDRYMADYTPRATEQ
HHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCC
SRPFPGTEYALKTLRDAGWTLAICTNKPVAAARRIVSELGLTEWFDAIGGGDSFPVRKPD
CCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCC
PAHLLGTIGLAHGHADRAIMVGDHHNDIFAAKGAHVRSVFARWGYGRPDMEAGATIGADS
HHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCEECCCH
MTEIPHIAGQLIPA
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]