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The map label for this gene is dnaA [H]

Identifier: 162147555

GI number: 162147555

Start: 1798138

End: 1799601

Strand: Direct

Name: dnaA [H]

Synonym: GDI_1771

Alternate gene names: 162147555

Gene position: 1798138-1799601 (Clockwise)

Preceding gene: 162147554

Following gene: 162147556

Centisome position: 45.59

GC content: 67.28

Gene sequence:

>1464_bases
ATGCGGGAATCTGCGTTCATCGTGTCGGGTGACCCGGTGGGGTACGGGCAGCGCGGGACGGTCGGTATGGCGGGGGCGGA
AAGCAGAGGGGCGGGCGATCCGGGCAACTGGACGAACATGCCCCCGAGGGGACCGGGAGTGGACATGACGGGCGAGTTAA
GTGGATTTGATGCCGTCGCGGAAGCCCGATCGGCCCGGAATGTCCTGGATATCCTGCGACCCGCTCTCCTGCGCGACTGG
GTGCGCACCCAGTATGGCGACCGGCTGAGCGCCCTGTGGAATGCCGAGCTTCCGGCGATCCGCCGCGTGGAACTGCAGGT
CGGCCGTCCGGAAGGCGCGGCCGACGGTGCCGCCCCCGCGCTCGCCGACCCGCCGGTGGCCGCGACGCCGGCCACCGCCG
CGATCGTGGGCGACGAGCGGGTGCCGGAAAACCGCAACGACCTCGCGGCGCCGCTCGACCCGCGCTTCACCTTCGATACG
TTCGTGGTCGGCAAGCCGAACGAATTCGCCTATGCCTGCGCCCGCCGGGTGGCCGAACGGCCGTCCAGCCCCGGGTTCAA
CCCGCTGTTCCTGTATGGCGGCGTCGGGCTGGGCAAGACCCACCTGATGCATGCCATCGGGTCGGAGCTGGTGCGGGGCG
GGGCGGTCTCGGTCGCCTACATGTCCGCCGAGAAATTCATGTACCGCTTCATTGCCGCCATCCGGTCGCAATCGACGATG
GAGTTCAAGGAGCAGTTGCGGTCGGTCGACGTGCTGATGATCGACGACCTGCAGTTCCTGATCGGCAAGGACAACACACA
GGAAGAATTCTTCCATACCTTCAACGCGCTGGTCGATGCCGGGCGGCAGATCGTGGTGTCGGCCGACAAGTCGCCGTCCG
ACCTGTCGGGGCTGGAGGACCGGCTGCGCACCCGTCTGGGCTGCGGCATGGTGGCGGACATCCATGCCACGACGTTCGAA
CTGCGGATCTCGATCCTGGAATCCAAGGCGGCGGCCTCGGGCGTCGCGGTGCCGGCCAAGGTGCTGGAATTCCTGGCGCA
CAAGATCACCTCGAACGTGCGCGAACTGGAAGGCGCGCTGAACCGGCTGATCGCCCATGCCAACCTGTTCGGCCGGCCGG
TGACGCTGGAAGCGACGCAGGATGTGCTGCACGACATCCTCAAGGCCCATGACCGGCGGGTGACGATCGAGGAAATCCAG
CGCAAGGTGTCCGAACACTGGAACATCCGCCTGACGGACATGTCCTCGGCCCGGCGTGCCCGCGCCGTGGCGCGCCCCCG
GCAGGTGGCGATGTACCTGGCCAAGCAGTTGACCAGCCGCTCGCTGCCGGAAATCGGGCGCAAGTTCGGCAATCGCGACC
ATACGACCGTCATGCACGCCGTCGCCCGCGTGACCGAACTGATGGAACGCGACACCGCGTTCGCCGAGGACGTGGAACTG
CTTCGCCGCATGCTGGAAAGCTGA

Upstream 100 bases:

>100_bases
GTTTTCCATTGCTTCGGCCGAGTCTGTGACCTATTCTTGCCCCTCTTCATACTGCGACGATGGGTGGGTTTTCGTGACCG
GGCCACTTTTGGCGTCGGGC

Downstream 100 bases:

>100_bases
CGGGAAGCCGCCTCTTTCGGGGGCCTTTCCGCGGTTGCCGGGGGCTGCTACTGTCAGGGCATCAACCCTGATACGCGACT
GCCGGACAACGATCCGGGTG

Product: chromosomal replication initiator protein dnaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MRESAFIVSGDPVGYGQRGTVGMAGAESRGAGDPGNWTNMPPRGPGVDMTGELSGFDAVAEARSARNVLDILRPALLRDW
VRTQYGDRLSALWNAELPAIRRVELQVGRPEGAADGAAPALADPPVAATPATAAIVGDERVPENRNDLAAPLDPRFTFDT
FVVGKPNEFAYACARRVAERPSSPGFNPLFLYGGVGLGKTHLMHAIGSELVRGGAVSVAYMSAEKFMYRFIAAIRSQSTM
EFKEQLRSVDVLMIDDLQFLIGKDNTQEEFFHTFNALVDAGRQIVVSADKSPSDLSGLEDRLRTRLGCGMVADIHATTFE
LRISILESKAAASGVAVPAKVLEFLAHKITSNVRELEGALNRLIAHANLFGRPVTLEATQDVLHDILKAHDRRVTIEEIQ
RKVSEHWNIRLTDMSSARRARAVARPRQVAMYLAKQLTSRSLPEIGRKFGNRDHTTVMHAVARVTELMERDTAFAEDVEL
LRRMLES

Sequences:

>Translated_487_residues
MRESAFIVSGDPVGYGQRGTVGMAGAESRGAGDPGNWTNMPPRGPGVDMTGELSGFDAVAEARSARNVLDILRPALLRDW
VRTQYGDRLSALWNAELPAIRRVELQVGRPEGAADGAAPALADPPVAATPATAAIVGDERVPENRNDLAAPLDPRFTFDT
FVVGKPNEFAYACARRVAERPSSPGFNPLFLYGGVGLGKTHLMHAIGSELVRGGAVSVAYMSAEKFMYRFIAAIRSQSTM
EFKEQLRSVDVLMIDDLQFLIGKDNTQEEFFHTFNALVDAGRQIVVSADKSPSDLSGLEDRLRTRLGCGMVADIHATTFE
LRISILESKAAASGVAVPAKVLEFLAHKITSNVRELEGALNRLIAHANLFGRPVTLEATQDVLHDILKAHDRRVTIEEIQ
RKVSEHWNIRLTDMSSARRARAVARPRQVAMYLAKQLTSRSLPEIGRKFGNRDHTTVMHAVARVTELMERDTAFAEDVEL
LRRMLES
>Mature_487_residues
MRESAFIVSGDPVGYGQRGTVGMAGAESRGAGDPGNWTNMPPRGPGVDMTGELSGFDAVAEARSARNVLDILRPALLRDW
VRTQYGDRLSALWNAELPAIRRVELQVGRPEGAADGAAPALADPPVAATPATAAIVGDERVPENRNDLAAPLDPRFTFDT
FVVGKPNEFAYACARRVAERPSSPGFNPLFLYGGVGLGKTHLMHAIGSELVRGGAVSVAYMSAEKFMYRFIAAIRSQSTM
EFKEQLRSVDVLMIDDLQFLIGKDNTQEEFFHTFNALVDAGRQIVVSADKSPSDLSGLEDRLRTRLGCGMVADIHATTFE
LRISILESKAAASGVAVPAKVLEFLAHKITSNVRELEGALNRLIAHANLFGRPVTLEATQDVLHDILKAHDRRVTIEEIQ
RKVSEHWNIRLTDMSSARRARAVARPRQVAMYLAKQLTSRSLPEIGRKFGNRDHTTVMHAVARVTELMERDTAFAEDVEL
LRRMLES

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=451, Percent_Identity=42.350332594235, Blast_Score=344, Evalue=6e-96,
Organism=Escherichia coli, GI226510964, Length=229, Percent_Identity=24.0174672489083, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 53351; Mature: 53351

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRESAFIVSGDPVGYGQRGTVGMAGAESRGAGDPGNWTNMPPRGPGVDMTGELSGFDAVA
CCCCCEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
EARSARNVLDILRPALLRDWVRTQYGDRLSALWNAELPAIRRVELQVGRPEGAADGAAPA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCC
LADPPVAATPATAAIVGDERVPENRNDLAAPLDPRFTFDTFVVGKPNEFAYACARRVAER
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEECEEEECCCCHHHHHHHHHHHHC
PSSPGFNPLFLYGGVGLGKTHLMHAIGSELVRGGAVSVAYMSAEKFMYRFIAAIRSQSTM
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCHH
EFKEQLRSVDVLMIDDLQFLIGKDNTQEEFFHTFNALVDAGRQIVVSADKSPSDLSGLED
HHHHHHHHCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
RLRTRLGCGMVADIHATTFELRISILESKAAASGVAVPAKVLEFLAHKITSNVRELEGAL
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NRLIAHANLFGRPVTLEATQDVLHDILKAHDRRVTIEEIQRKVSEHWNIRLTDMSSARRA
HHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCHHHHHH
RAVARPRQVAMYLAKQLTSRSLPEIGRKFGNRDHTTVMHAVARVTELMERDTAFAEDVEL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRMLES
HHHHHCC
>Mature Secondary Structure
MRESAFIVSGDPVGYGQRGTVGMAGAESRGAGDPGNWTNMPPRGPGVDMTGELSGFDAVA
CCCCCEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
EARSARNVLDILRPALLRDWVRTQYGDRLSALWNAELPAIRRVELQVGRPEGAADGAAPA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCC
LADPPVAATPATAAIVGDERVPENRNDLAAPLDPRFTFDTFVVGKPNEFAYACARRVAER
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEECEEEECCCCHHHHHHHHHHHHC
PSSPGFNPLFLYGGVGLGKTHLMHAIGSELVRGGAVSVAYMSAEKFMYRFIAAIRSQSTM
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCHH
EFKEQLRSVDVLMIDDLQFLIGKDNTQEEFFHTFNALVDAGRQIVVSADKSPSDLSGLED
HHHHHHHHCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
RLRTRLGCGMVADIHATTFELRISILESKAAASGVAVPAKVLEFLAHKITSNVRELEGAL
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
NRLIAHANLFGRPVTLEATQDVLHDILKAHDRRVTIEEIQRKVSEHWNIRLTDMSSARRA
HHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCHHHHHH
RAVARPRQVAMYLAKQLTSRSLPEIGRKFGNRDHTTVMHAVARVTELMERDTAFAEDVEL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRMLES
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA