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The map label for this gene is pcm [H]

Identifier: 162147545

GI number: 162147545

Start: 1785104

End: 1785820

Strand: Direct

Name: pcm [H]

Synonym: GDI_1761

Alternate gene names: 162147545

Gene position: 1785104-1785820 (Clockwise)

Preceding gene: 162147544

Following gene: 162147546

Centisome position: 45.26

GC content: 71.97

Gene sequence:

>717_bases
TTGCCGTGCGGTCGGGAAAGTTGTGAAGGGAGCGTCATGAACCAGTCCGCGCTTGGAGAAGCCGTCCTCGATTACGATGC
CGCGCGGCAAAGGATGGTGGATGCGCAGATCCGCCCGGTGGCGATCAACGATTCGCGAATCATCGCGGCGATGCGTGCCC
TGCCGCGCGAGGACTGCGTCCCCGAGGCGCTGCGCCCCTTCGCCTATGCCGACCAGAGCCTGGAGATCGGCCGCGGCCGC
GTGCTGACGGAACCGCGCATTGCCGGGCGGATGGTGCAGATCGCGGCCCCGCAGGCCGCGCAGCGCGCCCTGGTGGTGGG
GGCCGGGACGGGCTACCTGGCCGCGCTGCTGGCCCGGCTGGAACTGCAGGTCACGGCCCTGGAATCCGATGCCGCGCTCA
GCGCGATCGGCAAGGCCTTCTGCGCGGTCGAGGCACCGGGCGTCACCTGGGTGGACGGCCCGCTGCAGGCGGGCGACCCC
GCGCATGCGCCGTTCGACCTGATCGTGATCGACGGGGCGGTGCGTGAGGTCCCGCATGCCCTGCCGGGACAACTGGCCGA
GCACGGGCGCATCGTCTGCGTCATCTGGCCCCAGGGGGGCGTCGCCTCCGCCTGCATCGCCGAGCCCACCGCGCAGGGGC
TGGCGGTCCGCCGGGTCTTCGACGTCGCCCTGCCGCTGCTGCCGGAACTGGAGCCCGCGCCTGCCTTTGCGTTCTGA

Upstream 100 bases:

>100_bases
GTTGGCTATATCCACGCTCTGCCCCGCGCGGTCAAGCCGTTGTGTGCACGGGACATGCTAGGCAGATGGAACGCAGGGAC
ATAAAACGGCCCTGTGCCGC

Downstream 100 bases:

>100_bases
AGGCTGTAAACCCGTTCGCAACCGTTTGCGTGCATGAAACACGTCATGCGGCCTGAGGTGGCATTGTCGCGGGGGAGCGG
AATGAAGCGGAACTGTGGGA

Product: protein-L-isoaspartate O-methyltransferase

Products: NA

Alternate protein names: L-isoaspartyl protein carboxyl methyltransferase; Protein L-isoaspartyl methyltransferase; Protein-beta-aspartate methyltransferase; PIMT [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MPCGRESCEGSVMNQSALGEAVLDYDAARQRMVDAQIRPVAINDSRIIAAMRALPREDCVPEALRPFAYADQSLEIGRGR
VLTEPRIAGRMVQIAAPQAAQRALVVGAGTGYLAALLARLELQVTALESDAALSAIGKAFCAVEAPGVTWVDGPLQAGDP
AHAPFDLIVIDGAVREVPHALPGQLAEHGRIVCVIWPQGGVASACIAEPTAQGLAVRRVFDVALPLLPELEPAPAFAF

Sequences:

>Translated_238_residues
MPCGRESCEGSVMNQSALGEAVLDYDAARQRMVDAQIRPVAINDSRIIAAMRALPREDCVPEALRPFAYADQSLEIGRGR
VLTEPRIAGRMVQIAAPQAAQRALVVGAGTGYLAALLARLELQVTALESDAALSAIGKAFCAVEAPGVTWVDGPLQAGDP
AHAPFDLIVIDGAVREVPHALPGQLAEHGRIVCVIWPQGGVASACIAEPTAQGLAVRRVFDVALPLLPELEPAPAFAF
>Mature_237_residues
PCGRESCEGSVMNQSALGEAVLDYDAARQRMVDAQIRPVAINDSRIIAAMRALPREDCVPEALRPFAYADQSLEIGRGRV
LTEPRIAGRMVQIAAPQAAQRALVVGAGTGYLAALLARLELQVTALESDAALSAIGKAFCAVEAPGVTWVDGPLQAGDPA
HAPFDLIVIDGAVREVPHALPGQLAEHGRIVCVIWPQGGVASACIAEPTAQGLAVRRVFDVALPLLPELEPAPAFAF

Specific function: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins [H]

COG id: COG2518

COG function: function code O; Protein-L-isoaspartate carboxylmethyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789100, Length=159, Percent_Identity=32.7044025157233, Blast_Score=80, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000682 [H]

Pfam domain/function: PF01135 PCMT [H]

EC number: =2.1.1.77 [H]

Molecular weight: Translated: 24986; Mature: 24855

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCGRESCEGSVMNQSALGEAVLDYDAARQRMVDAQIRPVAINDSRIIAAMRALPREDCV
CCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCCCC
PEALRPFAYADQSLEIGRGRVLTEPRIAGRMVQIAAPQAAQRALVVGAGTGYLAALLARL
HHHHHHHHHCCCCCCCCCCEEECCCHHHCEEEEEECCHHHCEEEEEECCHHHHHHHHHHH
ELQVTALESDAALSAIGKAFCAVEAPGVTWVDGPLQAGDPAHAPFDLIVIDGAVREVPHA
HHEEEEECCHHHHHHHHHHHHEEECCCCEEECCCCCCCCCCCCCEEEEEECCHHHHCCCC
LPGQLAEHGRIVCVIWPQGGVASACIAEPTAQGLAVRRVFDVALPLLPELEPAPAFAF
CCHHHHHCCCEEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PCGRESCEGSVMNQSALGEAVLDYDAARQRMVDAQIRPVAINDSRIIAAMRALPREDCV
CCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCCCC
PEALRPFAYADQSLEIGRGRVLTEPRIAGRMVQIAAPQAAQRALVVGAGTGYLAALLARL
HHHHHHHHHCCCCCCCCCCEEECCCHHHCEEEEEECCHHHCEEEEEECCHHHHHHHHHHH
ELQVTALESDAALSAIGKAFCAVEAPGVTWVDGPLQAGDPAHAPFDLIVIDGAVREVPHA
HHEEEEECCHHHHHHHHHHHHEEECCCCEEECCCCCCCCCCCCCEEEEEECCHHHHCCCC
LPGQLAEHGRIVCVIWPQGGVASACIAEPTAQGLAVRRVFDVALPLLPELEPAPAFAF
CCHHHHHCCCEEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA