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The map label for this gene is glk [H]

Identifier: 162147544

GI number: 162147544

Start: 1783826

End: 1784794

Strand: Direct

Name: glk [H]

Synonym: GDI_1760

Alternate gene names: 162147544

Gene position: 1783826-1784794 (Clockwise)

Preceding gene: 162147543

Following gene: 162147545

Centisome position: 45.23

GC content: 69.45

Gene sequence:

>969_bases
ATGAGAGAGATCGTAGCCGTCGATATCGGCGGGACTCATGCGCGTTTCGCCATTGCCGGTGTCGAGGGCGGCCGTGTCAC
CCACCTGGGGGAAGCCACCACCCTGAAATGCGCGGAGCATGCCAGCCTGCAACTGGCGTGGGAGTCCTTCGCCCGTCAGG
TCGGCCGCACCCTGCCGCGTGCGGCGGGCATCGCCGTCGCCTGCCCGGTGCAGGGCGATATCCTGAAGCTGACGAACAAT
CCCTGGATCATCCAGCCGGCCCAACTGGCCGCGAAGCTGGATGTGGACCAGCATGTGCTGGTCAATGATTTCGGCGCGGT
GGGCCACGCCGTGGCCCAGGTGGACGCGGCCCATCTGCAGCACCTGTGCGGCCCGGACCGGCCGCTGCCCGCCAGCGGGG
TGACGACCATCGTCGGGCCGGGAACGGGGCTGGGCACCGCCTATGTCGTGCGGCGGGACGGCCGCTATCTGGTGTGCGAG
ACCGAAGGCGGCCATGTCGATTTCTCGCCCCTCGACATGCTGGAGGACAAGATCCTGCAGCGCCTGCGCCGGCGATATCG
CCGCGTGTCGACCGAGCGCGTCGTGTCGGGCCCGGGGCTGGTCAATCTGTACGAGGCGATCGCCGAAATCGAGGGCCTGC
CGGTCCGCACGCGCGACGACAAGGAATTATGGACCCTGGCGCTGGACGGAGCCGACCATATGGCCGCGGCGGCGCTGGAG
CGATTCTGCCTGGCGCTGGGGGCCGTCGCCGGTGACCTGGCGCTGTCGCAGGGTGGCAACAGCGTGGTGATCGCGGGCGG
CCTGGGCCTGCGGCTGGCCCAGCATCTGCCCCGGTCCGGATTCGCCGAGCGATTCGTCGCCAAGGGGCGATTCGAATCGC
TGATGGCCGACATGCCGGTCAAGCTGATCACCCACCCGCAGCCCGGCCTGTTCGGCGCGGCGGCGGCCTTCGCCGAGCGA
TTCGCCTGA

Upstream 100 bases:

>100_bases
TGACGTTGTGGCGTCGGGACGGGAAACCCGATCGGGCCGATAACGAAAACGTGCCCCGGGTACCTGCCGGGCAAGGAAGA
TCCAGGGAGTCTGACAGGAC

Downstream 100 bases:

>100_bases
TAAAAACGCCAACGTGTTCACCTTTTAGTGAATGCGTTGGCGCCGAAGCCGCGCGTGAATCCGGCACGGCAATGCTGCCA
TGCGCCACGCGAATCATTGA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MREIVAVDIGGTHARFAIAGVEGGRVTHLGEATTLKCAEHASLQLAWESFARQVGRTLPRAAGIAVACPVQGDILKLTNN
PWIIQPAQLAAKLDVDQHVLVNDFGAVGHAVAQVDAAHLQHLCGPDRPLPASGVTTIVGPGTGLGTAYVVRRDGRYLVCE
TEGGHVDFSPLDMLEDKILQRLRRRYRRVSTERVVSGPGLVNLYEAIAEIEGLPVRTRDDKELWTLALDGADHMAAAALE
RFCLALGAVAGDLALSQGGNSVVIAGGLGLRLAQHLPRSGFAERFVAKGRFESLMADMPVKLITHPQPGLFGAAAAFAER
FA

Sequences:

>Translated_322_residues
MREIVAVDIGGTHARFAIAGVEGGRVTHLGEATTLKCAEHASLQLAWESFARQVGRTLPRAAGIAVACPVQGDILKLTNN
PWIIQPAQLAAKLDVDQHVLVNDFGAVGHAVAQVDAAHLQHLCGPDRPLPASGVTTIVGPGTGLGTAYVVRRDGRYLVCE
TEGGHVDFSPLDMLEDKILQRLRRRYRRVSTERVVSGPGLVNLYEAIAEIEGLPVRTRDDKELWTLALDGADHMAAAALE
RFCLALGAVAGDLALSQGGNSVVIAGGLGLRLAQHLPRSGFAERFVAKGRFESLMADMPVKLITHPQPGLFGAAAAFAER
FA
>Mature_322_residues
MREIVAVDIGGTHARFAIAGVEGGRVTHLGEATTLKCAEHASLQLAWESFARQVGRTLPRAAGIAVACPVQGDILKLTNN
PWIIQPAQLAAKLDVDQHVLVNDFGAVGHAVAQVDAAHLQHLCGPDRPLPASGVTTIVGPGTGLGTAYVVRRDGRYLVCE
TEGGHVDFSPLDMLEDKILQRLRRRYRRVSTERVVSGPGLVNLYEAIAEIEGLPVRTRDDKELWTLALDGADHMAAAALE
RFCLALGAVAGDLALSQGGNSVVIAGGLGLRLAQHLPRSGFAERFVAKGRFESLMADMPVKLITHPQPGLFGAAAAFAER
FA

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=310, Percent_Identity=36.1290322580645, Blast_Score=178, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34234; Mature: 34234

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIVAVDIGGTHARFAIAGVEGGRVTHLGEATTLKCAEHASLQLAWESFARQVGRTLPR
CCEEEEEECCCCEEEEEEEECCCCCEEECCCCCEEEHHHCCHHHHHHHHHHHHHHHHCCH
AAGIAVACPVQGDILKLTNNPWIIQPAQLAAKLDVDQHVLVNDFGAVGHAVAQVDAAHLQ
HCCEEEECCCCCCEEEECCCCEEEEHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHH
HLCGPDRPLPASGVTTIVGPGTGLGTAYVVRRDGRYLVCETEGGHVDFSPLDMLEDKILQ
HHCCCCCCCCCCCCEEEECCCCCCCEEEEEEECCCEEEEECCCCEECCCHHHHHHHHHHH
RLRRRYRRVSTERVVSGPGLVNLYEAIAEIEGLPVRTRDDKELWTLALDGADHMAAAALE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHH
RFCLALGAVAGDLALSQGGNSVVIAGGLGLRLAQHLPRSGFAERFVAKGRFESLMADMPV
HHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCE
KLITHPQPGLFGAAAAFAERFA
EEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MREIVAVDIGGTHARFAIAGVEGGRVTHLGEATTLKCAEHASLQLAWESFARQVGRTLPR
CCEEEEEECCCCEEEEEEEECCCCCEEECCCCCEEEHHHCCHHHHHHHHHHHHHHHHCCH
AAGIAVACPVQGDILKLTNNPWIIQPAQLAAKLDVDQHVLVNDFGAVGHAVAQVDAAHLQ
HCCEEEECCCCCCEEEECCCCEEEEHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHH
HLCGPDRPLPASGVTTIVGPGTGLGTAYVVRRDGRYLVCETEGGHVDFSPLDMLEDKILQ
HHCCCCCCCCCCCCEEEECCCCCCCEEEEEEECCCEEEEECCCCEECCCHHHHHHHHHHH
RLRRRYRRVSTERVVSGPGLVNLYEAIAEIEGLPVRTRDDKELWTLALDGADHMAAAALE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHH
RFCLALGAVAGDLALSQGGNSVVIAGGLGLRLAQHLPRSGFAERFVAKGRFESLMADMPV
HHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCE
KLITHPQPGLFGAAAAFAERFA
EEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254282 [H]