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The map label for this gene is ttdR [H]

Identifier: 162147423

GI number: 162147423

Start: 1653029

End: 1653925

Strand: Reverse

Name: ttdR [H]

Synonym: GDI_1639

Alternate gene names: 162147423

Gene position: 1653925-1653029 (Counterclockwise)

Preceding gene: 162147429

Following gene: 162147419

Centisome position: 41.93

GC content: 69.45

Gene sequence:

>897_bases
ATGCGCGACGCGGACGAAATGCGGATTGTCGTCGAAATCGTCCGCCAGGGGGGCCTGTCGGCGGCGGCGCGCCATCTGGG
GCTGGCGCCGTCGGTGGTCAGCGACCGGCTGGCCCGGCTGGAGCAGCGCCTGGGCACCCGCCTGCTGGTGCGCACCACGC
GGCGCCAGACCCTGACCGAAGCCGGGCGGATCTACCTGGACGAGGCCACCGCCATCCTGGCCGCCACCGACGCCATGGAA
ACCCGGGTGCGCGAGACGGTGAACGCGCCCGGCGGCATGTTGCGCATCACCGCCCCCATGCCCTTCGGCCGGGTCCGGCT
GGCGCCCTTCGTCGCGGGCTTCATCAGCCGCCATCCCGACATCCGCATCCATCTGACGCTGGAGGACCGGATGGTGGATA
TTGTCGGCGAAGGATACGACATCGCCATTCGTGCCGCGCCCGTGGTGGACACCGCCCTGACCGGCCGGCGGCTGATGGAA
AGCCGGCGCGTGCTGGTGGCCAGTCCCGCCTATCTGTCGCGTCACGGCCGGCCGGAGACCCCCGCCGACCTGGCCCGCCA
TGCCTGCCTGGTGGCCAACATGACCGGCCAGTGCCGGGGAACCTGGCGCTTCGGCCGGGGCGAGAAGGCCCGCATTCACC
GGGTGGAAGGACGGCTGGCCTCCAGCCATTCCGAACTGCCGGTGGTGTGGGCGCTGGCCGGGCTGGGCCTGGCGCAGAAA
TCATTATGGGAGGTCGAGGCGCATCTGCGGGCTGGGCAACTGGTGACGGTGATGGAGGACTGGGAGCCTGACCCGGCTAC
CTTCTATGCCATCCATACCGTCAGTACCGTGCATTCGCACAAGATCGCGCTGTTCATGGGCGAACTGTTGCAGCCGGGGA
ATGGGGTGGTGGGTTAA

Upstream 100 bases:

>100_bases
TGTCTCCCGTCAGATTGATTGCGCGGAACTATGGGCGCCCGCACCGGGGAATGATAACCGTCGAATCCGGAAAACAGTTT
CCGGAAAGGGCGAAGGAACG

Downstream 100 bases:

>100_bases
GAGCCTGTTTGGAAAGTCGCTGAAGTGTGATTCAAGCTCTGGATGTGGACGCCAGAGCAGAGAGGCCGCATGGCCAGGAT
TACCCGCAAGACGAAGCGTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MRDADEMRIVVEIVRQGGLSAAARHLGLAPSVVSDRLARLEQRLGTRLLVRTTRRQTLTEAGRIYLDEATAILAATDAME
TRVRETVNAPGGMLRITAPMPFGRVRLAPFVAGFISRHPDIRIHLTLEDRMVDIVGEGYDIAIRAAPVVDTALTGRRLME
SRRVLVASPAYLSRHGRPETPADLARHACLVANMTGQCRGTWRFGRGEKARIHRVEGRLASSHSELPVVWALAGLGLAQK
SLWEVEAHLRAGQLVTVMEDWEPDPATFYAIHTVSTVHSHKIALFMGELLQPGNGVVG

Sequences:

>Translated_298_residues
MRDADEMRIVVEIVRQGGLSAAARHLGLAPSVVSDRLARLEQRLGTRLLVRTTRRQTLTEAGRIYLDEATAILAATDAME
TRVRETVNAPGGMLRITAPMPFGRVRLAPFVAGFISRHPDIRIHLTLEDRMVDIVGEGYDIAIRAAPVVDTALTGRRLME
SRRVLVASPAYLSRHGRPETPADLARHACLVANMTGQCRGTWRFGRGEKARIHRVEGRLASSHSELPVVWALAGLGLAQK
SLWEVEAHLRAGQLVTVMEDWEPDPATFYAIHTVSTVHSHKIALFMGELLQPGNGVVG
>Mature_298_residues
MRDADEMRIVVEIVRQGGLSAAARHLGLAPSVVSDRLARLEQRLGTRLLVRTTRRQTLTEAGRIYLDEATAILAATDAME
TRVRETVNAPGGMLRITAPMPFGRVRLAPFVAGFISRHPDIRIHLTLEDRMVDIVGEGYDIAIRAAPVVDTALTGRRLME
SRRVLVASPAYLSRHGRPETPADLARHACLVANMTGQCRGTWRFGRGEKARIHRVEGRLASSHSELPVVWALAGLGLAQK
SLWEVEAHLRAGQLVTVMEDWEPDPATFYAIHTVSTVHSHKIALFMGELLQPGNGVVG

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=279, Percent_Identity=32.6164874551971, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI87081978, Length=278, Percent_Identity=34.5323741007194, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1786401, Length=278, Percent_Identity=35.6115107913669, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=31.2714776632302, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787128, Length=257, Percent_Identity=29.5719844357977, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=28.719723183391, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787589, Length=294, Percent_Identity=29.9319727891156, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788706, Length=278, Percent_Identity=26.2589928057554, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790011, Length=266, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789173, Length=283, Percent_Identity=26.8551236749117, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=172, Percent_Identity=23.2558139534884, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32746; Mature: 32746

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDADEMRIVVEIVRQGGLSAAARHLGLAPSVVSDRLARLEQRLGTRLLVRTTRRQTLTE
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHH
AGRIYLDEATAILAATDAMETRVRETVNAPGGMLRITAPMPFGRVRLAPFVAGFISRHPD
HCEEEEECHHEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
IRIHLTLEDRMVDIVGEGYDIAIRAAPVVDTALTGRRLMESRRVLVASPAYLSRHGRPET
EEEEEEECCCEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCHHHHCCCCCCC
PADLARHACLVANMTGQCRGTWRFGRGEKARIHRVEGRLASSHSELPVVWALAGLGLAQK
HHHHHHHHHEEECCCCCCCEEEEECCCCCCEEEEECCHHHCCCCCCCHHHHHHHCCHHHH
SLWEVEAHLRAGQLVTVMEDWEPDPATFYAIHTVSTVHSHKIALFMGELLQPGNGVVG
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRDADEMRIVVEIVRQGGLSAAARHLGLAPSVVSDRLARLEQRLGTRLLVRTTRRQTLTE
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHH
AGRIYLDEATAILAATDAMETRVRETVNAPGGMLRITAPMPFGRVRLAPFVAGFISRHPD
HCEEEEECHHEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
IRIHLTLEDRMVDIVGEGYDIAIRAAPVVDTALTGRRLMESRRVLVASPAYLSRHGRPET
EEEEEEECCCEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCHHHHCCCCCCC
PADLARHACLVANMTGQCRGTWRFGRGEKARIHRVEGRLASSHSELPVVWALAGLGLAQK
HHHHHHHHHEEECCCCCCCEEEEECCCCCCEEEEECCHHHCCCCCCCHHHHHHHCCHHHH
SLWEVEAHLRAGQLVTVMEDWEPDPATFYAIHTVSTVHSHKIALFMGELLQPGNGVVG
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]