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The map label for this gene is argD [H]

Identifier: 162147259

GI number: 162147259

Start: 1467889

End: 1469094

Strand: Reverse

Name: argD [H]

Synonym: GDI_1464

Alternate gene names: 162147259

Gene position: 1469094-1467889 (Counterclockwise)

Preceding gene: 162147262

Following gene: 162147258

Centisome position: 37.25

GC content: 70.65

Gene sequence:

>1206_bases
ATGATCCCCGCCCTGATGCCCACTTACAACCGTGCCGACCTCGCTTTCGAGCGGGGCGAAGGCTGCTGGCTGTACGCGGC
GGACGGGCGACGATTCCTGGATCTGGGGGCGGGGATCGCGACCTCGTCCCTCGGGCACAACAACCCGCACCTGGTGTCGG
CCATTGCCGAACAGGCGGCGCGGGTGATGCATGTGTCGAATCTGTACCGCGTTCCGCAGGCCGAGCGGCTGGCCGAGCGG
CTGGTCGCCGCCAGCTTCGCCGACAGCGTGTTCTTCTGCAATTCGGGCGCCGAGGCGAACGAAGGCATGGTCAAGATGAT
CCGCCGCGCCCAGGCGCATGGCGGCCATCCCGAGCGCAACCGCATCATCTGCTTCGACGGCGCGTTCCACGGCCGGACGC
TGGCCATGCTGGCCGCCACCGGCAACCCGAAATACCTGGACGGGTTCGGCCCGGAGGTCGCGGGATTCGATCATGTGCCG
ATGAACAACATGAACGCCGTGCGCGCCGCCATCACGGCGGAAACCGCCGGCATCATGATCGAGCCGGTGCAGGGCGAAAG
CGGCATCAACGTCGCCGATCCGCGCTTCCTGCAGGAACTGCGCGCGGCGTGCGACGAATTCGGCCTGTATCTGGGCATGG
ACGAGGTCCAGTGCGGCATGGGCCGGACCGGGCGGCTGTTCGCCCATGAATGGTCGGGGGTGACGCCCGACGTGCTGTCC
ACCGCCAAGGGCATCGCCGGCGGCTTCCCGATGGGCGCCATCCTGGCGACCGAGGCCGTGGCCCGCCACCTGACGCCCGG
GTCGCACGGGACCACGTTCGGCGGCAACCCGCTGGCCTGCGCGGCCGCGAACGTGGTGCTGGACGTGCTGCTGGCCCCCG
GCTTCCTGGACCAGGTGCAGGCGCGCGGCGCGCAACTGGCCCGCGCGCTGGACGAACTGGTGGCCGAATTCCCGGACCTG
TTCGACGGGCGACGCGGCATCGGCCTGATGCTGGGCCTGCGCTGCACGGTTCCGGTCGCGCTGGTGCAGGATGCGGCGAT
GCATGAGGGCGTGCTGAGCGTCACCGCCGGGGACAACGTGCTGCGCCTGGTGCCCCCCCTGGTGATCACCGAGGCCGATT
GTGCCGAGGCCGGCCGGCGGCTGCGCCACGCGGCGCTGCGGGTGCGGGCGCACCTGGCGGCGACGGCCCGGGAGAGTGTG
GCATGA

Upstream 100 bases:

>100_bases
ATGGCCCACCCGCCCCGGCGCGTGGGCTCTTTCGCGTTTCCGCCTGGACACCCAAGACCCGGGCCCATGACCCGGACGCA
ACGATAAGGTCCCACCTTCC

Downstream 100 bases:

>100_bases
ACGCGCTGCCCACCACCACCCGGAACGCCGCCCCGCCCCGGCACTTCCTGGACCTGCGCGATTTCGACGGCGCGACGCTG
CGCGCCATCCTGGACCTGGG

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MIPALMPTYNRADLAFERGEGCWLYAADGRRFLDLGAGIATSSLGHNNPHLVSAIAEQAARVMHVSNLYRVPQAERLAER
LVAASFADSVFFCNSGAEANEGMVKMIRRAQAHGGHPERNRIICFDGAFHGRTLAMLAATGNPKYLDGFGPEVAGFDHVP
MNNMNAVRAAITAETAGIMIEPVQGESGINVADPRFLQELRAACDEFGLYLGMDEVQCGMGRTGRLFAHEWSGVTPDVLS
TAKGIAGGFPMGAILATEAVARHLTPGSHGTTFGGNPLACAAANVVLDVLLAPGFLDQVQARGAQLARALDELVAEFPDL
FDGRRGIGLMLGLRCTVPVALVQDAAMHEGVLSVTAGDNVLRLVPPLVITEADCAEAGRRLRHAALRVRAHLAATARESV
A

Sequences:

>Translated_401_residues
MIPALMPTYNRADLAFERGEGCWLYAADGRRFLDLGAGIATSSLGHNNPHLVSAIAEQAARVMHVSNLYRVPQAERLAER
LVAASFADSVFFCNSGAEANEGMVKMIRRAQAHGGHPERNRIICFDGAFHGRTLAMLAATGNPKYLDGFGPEVAGFDHVP
MNNMNAVRAAITAETAGIMIEPVQGESGINVADPRFLQELRAACDEFGLYLGMDEVQCGMGRTGRLFAHEWSGVTPDVLS
TAKGIAGGFPMGAILATEAVARHLTPGSHGTTFGGNPLACAAANVVLDVLLAPGFLDQVQARGAQLARALDELVAEFPDL
FDGRRGIGLMLGLRCTVPVALVQDAAMHEGVLSVTAGDNVLRLVPPLVITEADCAEAGRRLRHAALRVRAHLAATARESV
A
>Mature_401_residues
MIPALMPTYNRADLAFERGEGCWLYAADGRRFLDLGAGIATSSLGHNNPHLVSAIAEQAARVMHVSNLYRVPQAERLAER
LVAASFADSVFFCNSGAEANEGMVKMIRRAQAHGGHPERNRIICFDGAFHGRTLAMLAATGNPKYLDGFGPEVAGFDHVP
MNNMNAVRAAITAETAGIMIEPVQGESGINVADPRFLQELRAACDEFGLYLGMDEVQCGMGRTGRLFAHEWSGVTPDVLS
TAKGIAGGFPMGAILATEAVARHLTPGSHGTTFGGNPLACAAANVVLDVLLAPGFLDQVQARGAQLARALDELVAEFPDL
FDGRRGIGLMLGLRCTVPVALVQDAAMHEGVLSVTAGDNVLRLVPPLVITEADCAEAGRRLRHAALRVRAHLAATARESV
A

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=380, Percent_Identity=30.5263157894737, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI284507298, Length=294, Percent_Identity=32.9931972789116, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI13994255, Length=381, Percent_Identity=30.7086614173228, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI24119277, Length=401, Percent_Identity=24.9376558603491, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI188536080, Length=416, Percent_Identity=26.4423076923077, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38679950, Length=416, Percent_Identity=26.4423076923077, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38679946, Length=416, Percent_Identity=26.4423076923077, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI37574042, Length=410, Percent_Identity=26.0975609756098, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI226442709, Length=384, Percent_Identity=26.5625, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226442705, Length=407, Percent_Identity=24.5700245700246, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1789759, Length=388, Percent_Identity=40.979381443299, Blast_Score=314, Evalue=7e-87,
Organism=Escherichia coli, GI1788044, Length=375, Percent_Identity=41.8666666666667, Blast_Score=285, Evalue=5e-78,
Organism=Escherichia coli, GI145693181, Length=385, Percent_Identity=35.8441558441558, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789016, Length=389, Percent_Identity=34.9614395886889, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787560, Length=402, Percent_Identity=33.3333333333333, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1786991, Length=386, Percent_Identity=33.419689119171, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1786349, Length=317, Percent_Identity=32.1766561514196, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=31.8421052631579, Blast_Score=207, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI25144274, Length=264, Percent_Identity=33.7121212121212, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=27.8801843317972, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17541228, Length=422, Percent_Identity=26.7772511848341, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=25.0585480093677, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71981843, Length=163, Percent_Identity=30.0613496932515, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=390, Percent_Identity=37.6923076923077, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6323470, Length=399, Percent_Identity=28.0701754385965, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324386, Length=413, Percent_Identity=24.455205811138, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357415, Length=389, Percent_Identity=29.0488431876607, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI28574759, Length=428, Percent_Identity=28.9719626168224, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI161085790, Length=452, Percent_Identity=27.8761061946903, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI281366494, Length=425, Percent_Identity=27.0588235294118, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24667139, Length=425, Percent_Identity=27.0588235294118, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24667143, Length=425, Percent_Identity=27.0588235294118, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21356575, Length=419, Percent_Identity=26.9689737470167, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42467; Mature: 42467

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPALMPTYNRADLAFERGEGCWLYAADGRRFLDLGAGIATSSLGHNNPHLVSAIAEQAA
CCCCCCCCCCCCCCEEECCCCEEEEECCCCEEEECCCCHHHCCCCCCCCHHHHHHHHHHH
RVMHVSNLYRVPQAERLAERLVAASFADSVFFCNSGAEANEGMVKMIRRAQAHGGHPERN
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
RIICFDGAFHGRTLAMLAATGNPKYLDGFGPEVAGFDHVPMNNMNAVRAAITAETAGIMI
EEEEEECCCCCCEEEEEEECCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEE
EPVQGESGINVADPRFLQELRAACDEFGLYLGMDEVQCGMGRTGRLFAHEWSGVTPDVLS
EECCCCCCCCCCCHHHHHHHHHHHHHHCEEECCHHHHHCCCCCCCEEEECCCCCCHHHHH
TAKGIAGGFPMGAILATEAVARHLTPGSHGTTFGGNPLACAAANVVLDVLLAPGFLDQVQ
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
ARGAQLARALDELVAEFPDLFDGRRGIGLMLGLRCTVPVALVQDAAMHEGVLSVTAGDNV
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEECCCCE
LRLVPPLVITEADCAEAGRRLRHAALRVRAHLAATARESVA
EECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIPALMPTYNRADLAFERGEGCWLYAADGRRFLDLGAGIATSSLGHNNPHLVSAIAEQAA
CCCCCCCCCCCCCCEEECCCCEEEEECCCCEEEECCCCHHHCCCCCCCCHHHHHHHHHHH
RVMHVSNLYRVPQAERLAERLVAASFADSVFFCNSGAEANEGMVKMIRRAQAHGGHPERN
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
RIICFDGAFHGRTLAMLAATGNPKYLDGFGPEVAGFDHVPMNNMNAVRAAITAETAGIMI
EEEEEECCCCCCEEEEEEECCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEE
EPVQGESGINVADPRFLQELRAACDEFGLYLGMDEVQCGMGRTGRLFAHEWSGVTPDVLS
EECCCCCCCCCCCHHHHHHHHHHHHHHCEEECCHHHHHCCCCCCCEEEECCCCCCHHHHH
TAKGIAGGFPMGAILATEAVARHLTPGSHGTTFGGNPLACAAANVVLDVLLAPGFLDQVQ
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
ARGAQLARALDELVAEFPDLFDGRRGIGLMLGLRCTVPVALVQDAAMHEGVLSVTAGDNV
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEECCCCE
LRLVPPLVITEADCAEAGRRLRHAALRVRAHLAATARESVA
EECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]