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The map label for this gene is degP [H]

Identifier: 162147252

GI number: 162147252

Start: 1458527

End: 1459729

Strand: Reverse

Name: degP [H]

Synonym: GDI_1457

Alternate gene names: 162147252

Gene position: 1459729-1458527 (Counterclockwise)

Preceding gene: 162147253

Following gene: 162147251

Centisome position: 37.01

GC content: 70.32

Gene sequence:

>1203_bases
GTGACCGCCGCCGCCATGACGGCGGCGCGAACATGCGCTATCGTCGCGATATCCGTAACGCGCCGACCCATGCGCCATGA
ACAGGATGTCATACCCATGCGGATGGTAAGCCGGCCGAAGCGTTGCGCGGCGGCCGTGGCCGGCCTGGCCCTGGGTTTCA
CCTGCGCCACCGCGCGGGCCGACGCCCCCCTGTTCGCGCCGCCCGCGCCGCCGCTGGTCACCTCCGGGCCGCTGACCTTC
GCGCCGCTGGTGCGTCAGGTGGTGCCGGCCGTGGTCAATATCGCCGTGACGCAGGATGCCGACGACCCGCAGAAGCGCGT
GCCGGTTCCCCCGGGCGTCAAGGGCACGCCCTTCGAGAAGCGGTTCCGCGAGCGCATGCGCTCGCGCGGCGAGGAGATGC
TGGGCGCCGGATCGGGCTTCATCATCGACCCCAGCGGCGTGATCGTGACCAACAACCATGTGGTGGGCGAGGCCGACCAC
ATCACGGTCTCGCTGTCCGACGGAACCGAATATCCCGCCCGTCTGGTGGGCAGCGACGACCTGACCGACATCGCGGTCAT
CAGCATCCAGGCCCCGCATCCGCTGCCGTTCGTGACCTGGGGCGACAGCCGGCAGATCAATGTCGGCGACTGGATCATGG
CGGCGGGCAACCCGTTCGGCCTGGGCTCGTCCGTCACCGCCGGGATCGTGTCCGCGCGCGGGCGCGATATCGGCGCCAGC
CCGTTCGACGATTTCCTGCAACTGGACGCGCCGATCAATCCCGGCAATTCGGGGGGGCCGTCGTTCAACCTCAGCGGCCA
GGTGGTGGCGCTGAACACCGCCATCGTGTCGCCCACCGGCGGGTCGGTGGGAATCGGCTTCGGCATTCCGTCGGAAATCG
TGGCCCCCATCGTGGCCGAACTGCGCCGCAGCGGGCACATCGCGCGCGGCTGGCTGGGCGTGACCCTGGCGGATGGCGAC
ACCCATGACGGGGTGCGCATCACCGACATCGACCATGACGGCCCCGCCCAGCGGGCCAGGCTGCGCACCGGCGACATCGT
GCTGAGCGTGGGGGACGAACCGATGGATACCTCCCGCACCCTGATCCGCACCATCGCGGCGGAACATCCCGGTTCGACCG
TGCAGGTCCGCATCCGCCGCCACGGCGCCGTGCTGACGGTGCCGGTCGCGGTGGGAAGCCGGCCGGCGGATATGGACGAC
TAG

Upstream 100 bases:

>100_bases
CGGACATGCGCCGCGACATGCGCGGGCGCTACCCCCGCCACGACTGGCCGGAAAACCCGGCGACCGCCGCGCCCCCCGCG
CGTCATGCCGGCCGCCGGCC

Downstream 100 bases:

>100_bases
GTACCTCCCGCTCTGGCCAGTGCGGCCGCATGCAGCGTAAGATGATCGGCCAAGGTTGAAACGGGAGCCGGACCGACATG
CATATCCTGGTCGTCGAGGA

Product: protease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTAAAMTAARTCAIVAISVTRRPMRHEQDVIPMRMVSRPKRCAAAVAGLALGFTCATARADAPLFAPPAPPLVTSGPLTF
APLVRQVVPAVVNIAVTQDADDPQKRVPVPPGVKGTPFEKRFRERMRSRGEEMLGAGSGFIIDPSGVIVTNNHVVGEADH
ITVSLSDGTEYPARLVGSDDLTDIAVISIQAPHPLPFVTWGDSRQINVGDWIMAAGNPFGLGSSVTAGIVSARGRDIGAS
PFDDFLQLDAPINPGNSGGPSFNLSGQVVALNTAIVSPTGGSVGIGFGIPSEIVAPIVAELRRSGHIARGWLGVTLADGD
THDGVRITDIDHDGPAQRARLRTGDIVLSVGDEPMDTSRTLIRTIAAEHPGSTVQVRIRRHGAVLTVPVAVGSRPADMDD

Sequences:

>Translated_400_residues
MTAAAMTAARTCAIVAISVTRRPMRHEQDVIPMRMVSRPKRCAAAVAGLALGFTCATARADAPLFAPPAPPLVTSGPLTF
APLVRQVVPAVVNIAVTQDADDPQKRVPVPPGVKGTPFEKRFRERMRSRGEEMLGAGSGFIIDPSGVIVTNNHVVGEADH
ITVSLSDGTEYPARLVGSDDLTDIAVISIQAPHPLPFVTWGDSRQINVGDWIMAAGNPFGLGSSVTAGIVSARGRDIGAS
PFDDFLQLDAPINPGNSGGPSFNLSGQVVALNTAIVSPTGGSVGIGFGIPSEIVAPIVAELRRSGHIARGWLGVTLADGD
THDGVRITDIDHDGPAQRARLRTGDIVLSVGDEPMDTSRTLIRTIAAEHPGSTVQVRIRRHGAVLTVPVAVGSRPADMDD
>Mature_399_residues
TAAAMTAARTCAIVAISVTRRPMRHEQDVIPMRMVSRPKRCAAAVAGLALGFTCATARADAPLFAPPAPPLVTSGPLTFA
PLVRQVVPAVVNIAVTQDADDPQKRVPVPPGVKGTPFEKRFRERMRSRGEEMLGAGSGFIIDPSGVIVTNNHVVGEADHI
TVSLSDGTEYPARLVGSDDLTDIAVISIQAPHPLPFVTWGDSRQINVGDWIMAAGNPFGLGSSVTAGIVSARGRDIGASP
FDDFLQLDAPINPGNSGGPSFNLSGQVVALNTAIVSPTGGSVGIGFGIPSEIVAPIVAELRRSGHIARGWLGVTLADGDT
HDGVRITDIDHDGPAQRARLRTGDIVLSVGDEPMDTSRTLIRTIAAEHPGSTVQVRIRRHGAVLTVPVAVGSRPADMDD

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=326, Percent_Identity=30.3680981595092, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI22129776, Length=285, Percent_Identity=31.5789473684211, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI24308541, Length=258, Percent_Identity=31.7829457364341, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI7019477, Length=279, Percent_Identity=32.258064516129, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1789629, Length=326, Percent_Identity=38.0368098159509, Blast_Score=217, Evalue=9e-58,
Organism=Escherichia coli, GI1786356, Length=341, Percent_Identity=35.1906158357771, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1789630, Length=280, Percent_Identity=37.8571428571429, Blast_Score=173, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24646839, Length=263, Percent_Identity=31.9391634980989, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41778; Mature: 41647

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAAMTAARTCAIVAISVTRRPMRHEQDVIPMRMVSRPKRCAAAVAGLALGFTCATARA
CCCHHHHHHHEEEEEEEEECCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHEEECCCC
DAPLFAPPAPPLVTSGPLTFAPLVRQVVPAVVNIAVTQDADDPQKRVPVPPGVKGTPFEK
CCCCCCCCCCCCEECCCCHHHHHHHHHHHHHEEEEEECCCCCHHHCCCCCCCCCCCCHHH
RFRERMRSRGEEMLGAGSGFIIDPSGVIVTNNHVVGEADHITVSLSDGTEYPARLVGSDD
HHHHHHHHCCHHHHCCCCCEEECCCCEEEECCEEECCCCEEEEEECCCCCCCCEECCCCC
LTDIAVISIQAPHPLPFVTWGDSRQINVGDWIMAAGNPFGLGSSVTAGIVSARGRDIGAS
CCEEEEEEEECCCCCCEEEECCCCEEECCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCC
PFDDFLQLDAPINPGNSGGPSFNLSGQVVALNTAIVSPTGGSVGIGFGIPSEIVAPIVAE
CCHHHHEECCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEECCCCCHHHHHHHHHH
LRRSGHIARGWLGVTLADGDTHDGVRITDIDHDGPAQRARLRTGDIVLSVGDEPMDTSRT
HHHCCCEEEEEEEEEEECCCCCCCEEEEECCCCCCHHHHEEECCCEEEEECCCCCCHHHH
LIRTIAAEHPGSTVQVRIRRHGAVLTVPVAVGSRPADMDD
HHHHHHHCCCCCEEEEEEEECCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
TAAAMTAARTCAIVAISVTRRPMRHEQDVIPMRMVSRPKRCAAAVAGLALGFTCATARA
CCHHHHHHHEEEEEEEEECCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHEEECCCC
DAPLFAPPAPPLVTSGPLTFAPLVRQVVPAVVNIAVTQDADDPQKRVPVPPGVKGTPFEK
CCCCCCCCCCCCEECCCCHHHHHHHHHHHHHEEEEEECCCCCHHHCCCCCCCCCCCCHHH
RFRERMRSRGEEMLGAGSGFIIDPSGVIVTNNHVVGEADHITVSLSDGTEYPARLVGSDD
HHHHHHHHCCHHHHCCCCCEEECCCCEEEECCEEECCCCEEEEEECCCCCCCCEECCCCC
LTDIAVISIQAPHPLPFVTWGDSRQINVGDWIMAAGNPFGLGSSVTAGIVSARGRDIGAS
CCEEEEEEEECCCCCCEEEECCCCEEECCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCC
PFDDFLQLDAPINPGNSGGPSFNLSGQVVALNTAIVSPTGGSVGIGFGIPSEIVAPIVAE
CCHHHHEECCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEECCCCCHHHHHHHHHH
LRRSGHIARGWLGVTLADGDTHDGVRITDIDHDGPAQRARLRTGDIVLSVGDEPMDTSRT
HHHCCCEEEEEEEEEEECCCCCCCEEEEECCCCCCHHHHEEECCCEEEEECCCCCCHHHH
LIRTIAAEHPGSTVQVRIRRHGAVLTVPVAVGSRPADMDD
HHHHHHHCCCCCEEEEEEEECCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]