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The map label for this gene is guaD [H]

Identifier: 162147221

GI number: 162147221

Start: 1430300

End: 1430806

Strand: Reverse

Name: guaD [H]

Synonym: GDI_1426

Alternate gene names: 162147221

Gene position: 1430806-1430300 (Counterclockwise)

Preceding gene: 162147222

Following gene: 162147220

Centisome position: 36.28

GC content: 72.58

Gene sequence:

>507_bases
ATGCATGAAGCCCCCACACCGACCGACCTGGACCTGCTGCGGCGGGCCATCGCGCTGTCGGCGGACGCTCGCGCGCAGGG
GCGGCATCCGTTCGCGGCGCTGGTCGCCGATGCGCAGGGGCGGGTGGTCAGCACCGCCATCAACAATTCCATGCCGCCCG
AAGGCGATCCGACGCAGCATGCCGAACTGCGCGCCGTGGCCGGCGCCGCGCGCATCCTGCCGCCCGACGCGATGGCGGAC
TGCACGCTTTATACCAGCGCCGAGCCCTGCTGCATGTGTGCCGGCGCGGTCTACTGGACCAATATCCGCCGCGTGGTCTA
CGCGCTGTCGGAGCACCGGCTGCTGGCCCTGACCGGCGCGCACCCGGAAAACCCGACCTTCGCCCTGCCCTGCCGCGAGG
TATTCGCCCGTGGGCAGCACCCCGTCGCGGTGCTGGGCCCGATGCTGGAGGACGAAGCCGCCGGCCCGCATGCGGGCTTC
TGGTGCGACGGCCCGCCGGCAGGCTGA

Upstream 100 bases:

>100_bases
GCCAGCGGCGTGTTCATGGCGGCGTTCTGCGCGGTGACGCTGAACCTGCTGCTGTCCCCGGACCAGATATCCCGGACCGG
ACCCTGCGAGGACGCAACCG

Downstream 100 bases:

>100_bases
TCCCCCCGCCCCCCCGGCCGGTCCCCGGGCGCGGCGCGGGATTGCAACCGGAAGACGGGCATGCCAAGTGTGCCCTTGCG
TCCCGAGCGGTCCCGGATGT

Product: cytidine deaminase

Products: NA

Alternate protein names: GDEase; Guanase; Guanine aminase; Guanine aminohydrolase; GAH [H]

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MHEAPTPTDLDLLRRAIALSADARAQGRHPFAALVADAQGRVVSTAINNSMPPEGDPTQHAELRAVAGAARILPPDAMAD
CTLYTSAEPCCMCAGAVYWTNIRRVVYALSEHRLLALTGAHPENPTFALPCREVFARGQHPVAVLGPMLEDEAAGPHAGF
WCDGPPAG

Sequences:

>Translated_168_residues
MHEAPTPTDLDLLRRAIALSADARAQGRHPFAALVADAQGRVVSTAINNSMPPEGDPTQHAELRAVAGAARILPPDAMAD
CTLYTSAEPCCMCAGAVYWTNIRRVVYALSEHRLLALTGAHPENPTFALPCREVFARGQHPVAVLGPMLEDEAAGPHAGF
WCDGPPAG
>Mature_168_residues
MHEAPTPTDLDLLRRAIALSADARAQGRHPFAALVADAQGRVVSTAINNSMPPEGDPTQHAELRAVAGAARILPPDAMAD
CTLYTSAEPCCMCAGAVYWTNIRRVVYALSEHRLLALTGAHPENPTFALPCREVFARGQHPVAVLGPMLEDEAAGPHAGF
WCDGPPAG

Specific function: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.3 [H]

Molecular weight: Translated: 17770; Mature: 17770

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEAPTPTDLDLLRRAIALSADARAQGRHPFAALVADAQGRVVSTAINNSMPPEGDPTQH
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCH
AELRAVAGAARILPPDAMADCTLYTSAEPCCMCAGAVYWTNIRRVVYALSEHRLLALTGA
HHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
HPENPTFALPCREVFARGQHPVAVLGPMLEDEAAGPHAGFWCDGPPAG
CCCCCEEECCHHHHHHCCCCCCEECCCHHHHCCCCCCCCEECCCCCCC
>Mature Secondary Structure
MHEAPTPTDLDLLRRAIALSADARAQGRHPFAALVADAQGRVVSTAINNSMPPEGDPTQH
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCH
AELRAVAGAARILPPDAMADCTLYTSAEPCCMCAGAVYWTNIRRVVYALSEHRLLALTGA
HHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
HPENPTFALPCREVFARGQHPVAVLGPMLEDEAAGPHAGFWCDGPPAG
CCCCCEEECCHHHHHHCCCCCCEECCCHHHHCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11101664 [H]