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The map label for this gene is ygfU [H]

Identifier: 162147222

GI number: 162147222

Start: 1430799

End: 1432139

Strand: Reverse

Name: ygfU [H]

Synonym: GDI_1427

Alternate gene names: 162147222

Gene position: 1432139-1430799 (Counterclockwise)

Preceding gene: 162147223

Following gene: 162147221

Centisome position: 36.31

GC content: 71.74

Gene sequence:

>1341_bases
ATGAACCATGTCGCGAACCGGCCCGACCCTGTCGAGGCGCGCCTGCCGCCCTGGCAGCTTCTGGTCTGCGGTTTGCAGCA
TGTGCTGGTGATCTATGCCGGGATCGTCGCGGTGCCGCTGATCATCGGCAGCACGCTGGGGCTGGACGGCGCACAGCAGG
CGATGCTGGTCAATGCCAGCATCCTGACATCCGGCATCGCCACGCTGGTCCAGACCCTGGGGCTGGGCCCGTTCGGCGCA
CGCCTGCCGCTGATCCAGGCATCGTCCTTCATCGCCCTGCCGCCCATGGTCATGATCGCGCGGGAATACGACCTGCCGAC
CGCCTATGGCGCGGTCATCGGCGGCGGGCTGGCCACCTGCCTGCTGGCGCCCCTGGCCAGCCGGCTGACGCGCTTCTTCC
CGCCCGTGGTGATCGGCAGCGTGATCACCGTCGTCGGGCTGTCGCTGATGCCGGCGGCGGCGAACTGGCTGGGCGGGGGG
CGGCCGGGGGACCCCGGCTTCGGCGCGCCCGCGCACCTGCTGCTGGGTTTCGCGACCCTGGCCCTGACCCTGCTGATCAC
CGCGCGGGCCGGCGGCATGGGGCGGACGCTGGCCATCCTGCTGGGCATGGCGGCCGGCTGCGTGCTGGGCATCCTGACCG
GGCAGGCCGATTTCACCCCCATGCGCCAGGTGGCGTGGATGGCGCCGCCGCCGGTGCTGCCATTTGGCGCACCGGCCTTC
CACACCGTGCCGATCCTGGTCATGACCATGGCGATGATGGTCATCCTGGTGGAGACCACCGGCAACTGCCTGGCCGTCTC
GCGCCTGGCGGGGCGGACGGCATCGCGCGCGGTGCTGGCGCGCACCTATGCCGCCGATGGATTGTCCACCCTGCTGGGCG
GATTCCTGGGCGGCACGCCCTATAACGCCTTCGCCCAGAATACCGGGCTGATCGCCCTGACCGGCGTGCGCAGCCGCTTC
GTCGTCGCGGCGGCGGGCGCCCTGATGGTCGCAATGGGCCTGTTTCCCCGCCTGGGCGCCGCCGTCGCCTGCATGCCCCG
GCCGGTCCTGGGCGGTTCGGCGATCCTGATGTTCGGCATGACCGCGATGGCCGGCATCCAGGACCTGGCGCGCATCCGCC
CCTCCGGCACGGCGCACGCGCTGGTCGCCGCCGTGGCGATCGGGGCGGGCGTGCTGCCGATGGCCTGCCCGACCCTGTTC
GCCCACCTGCCCGGTCCGCTGCGCATCCTGACCGCCAGCGGCGTGTTCATGGCGGCGTTCTGCGCGGTGACGCTGAACCT
GCTGCTGTCCCCGGACCAGATATCCCGGACCGGACCCTGCGAGGACGCAACCGATGCATGA

Upstream 100 bases:

>100_bases
ACGATTCCGCCGGAATGAATACCTGGCTGCACAGGCAGGTCATGCAGAAGCTGGCGGACAATGGCGGCAAGGTTCCCGAC
GACCTGAAATGACCCGCTGA

Downstream 100 bases:

>100_bases
AGCCCCCACACCGACCGACCTGGACCTGCTGCGGCGGGCCATCGCGCTGTCGGCGGACGCTCGCGCGCAGGGGCGGCATC
CGTTCGCGGCGCTGGTCGCC

Product: permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MNHVANRPDPVEARLPPWQLLVCGLQHVLVIYAGIVAVPLIIGSTLGLDGAQQAMLVNASILTSGIATLVQTLGLGPFGA
RLPLIQASSFIALPPMVMIAREYDLPTAYGAVIGGGLATCLLAPLASRLTRFFPPVVIGSVITVVGLSLMPAAANWLGGG
RPGDPGFGAPAHLLLGFATLALTLLITARAGGMGRTLAILLGMAAGCVLGILTGQADFTPMRQVAWMAPPPVLPFGAPAF
HTVPILVMTMAMMVILVETTGNCLAVSRLAGRTASRAVLARTYAADGLSTLLGGFLGGTPYNAFAQNTGLIALTGVRSRF
VVAAAGALMVAMGLFPRLGAAVACMPRPVLGGSAILMFGMTAMAGIQDLARIRPSGTAHALVAAVAIGAGVLPMACPTLF
AHLPGPLRILTASGVFMAAFCAVTLNLLLSPDQISRTGPCEDATDA

Sequences:

>Translated_446_residues
MNHVANRPDPVEARLPPWQLLVCGLQHVLVIYAGIVAVPLIIGSTLGLDGAQQAMLVNASILTSGIATLVQTLGLGPFGA
RLPLIQASSFIALPPMVMIAREYDLPTAYGAVIGGGLATCLLAPLASRLTRFFPPVVIGSVITVVGLSLMPAAANWLGGG
RPGDPGFGAPAHLLLGFATLALTLLITARAGGMGRTLAILLGMAAGCVLGILTGQADFTPMRQVAWMAPPPVLPFGAPAF
HTVPILVMTMAMMVILVETTGNCLAVSRLAGRTASRAVLARTYAADGLSTLLGGFLGGTPYNAFAQNTGLIALTGVRSRF
VVAAAGALMVAMGLFPRLGAAVACMPRPVLGGSAILMFGMTAMAGIQDLARIRPSGTAHALVAAVAIGAGVLPMACPTLF
AHLPGPLRILTASGVFMAAFCAVTLNLLLSPDQISRTGPCEDATDA
>Mature_446_residues
MNHVANRPDPVEARLPPWQLLVCGLQHVLVIYAGIVAVPLIIGSTLGLDGAQQAMLVNASILTSGIATLVQTLGLGPFGA
RLPLIQASSFIALPPMVMIAREYDLPTAYGAVIGGGLATCLLAPLASRLTRFFPPVVIGSVITVVGLSLMPAAANWLGGG
RPGDPGFGAPAHLLLGFATLALTLLITARAGGMGRTLAILLGMAAGCVLGILTGQADFTPMRQVAWMAPPPVLPFGAPAF
HTVPILVMTMAMMVILVETTGNCLAVSRLAGRTASRAVLARTYAADGLSTLLGGFLGGTPYNAFAQNTGLIALTGVRSRF
VVAAAGALMVAMGLFPRLGAAVACMPRPVLGGSAILMFGMTAMAGIQDLARIRPSGTAHALVAAVAIGAGVLPMACPTLF
AHLPGPLRILTASGVFMAAFCAVTLNLLLSPDQISRTGPCEDATDA

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680145, Length=458, Percent_Identity=24.8908296943231, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI44680143, Length=462, Percent_Identity=24.6753246753247, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI87082181, Length=446, Percent_Identity=37.8923766816144, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI1790087, Length=440, Percent_Identity=30, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI87082178, Length=451, Percent_Identity=27.9379157427938, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87081818, Length=447, Percent_Identity=28.8590604026846, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1788843, Length=454, Percent_Identity=26.2114537444934, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17558856, Length=493, Percent_Identity=22.5152129817444, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17542262, Length=412, Percent_Identity=21.3592233009709, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356175, Length=445, Percent_Identity=23.3707865168539, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45391; Mature: 45391

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHVANRPDPVEARLPPWQLLVCGLQHVLVIYAGIVAVPLIIGSTLGLDGAQQAMLVNAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ILTSGIATLVQTLGLGPFGARLPLIQASSFIALPPMVMIAREYDLPTAYGAVIGGGLATC
HHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHCCCHHHHHHHCCCCHHHHHHHHHHHHHH
LLAPLASRLTRFFPPVVIGSVITVVGLSLMPAAANWLGGGRPGDPGFGAPAHLLLGFATL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
ALTLLITARAGGMGRTLAILLGMAAGCVLGILTGQADFTPMRQVAWMAPPPVLPFGAPAF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCHH
HTVPILVMTMAMMVILVETTGNCLAVSRLAGRTASRAVLARTYAADGLSTLLGGFLGGTP
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YNAFAQNTGLIALTGVRSRFVVAAAGALMVAMGLFPRLGAAVACMPRPVLGGSAILMFGM
CHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHH
TAMAGIQDLARIRPSGTAHALVAAVAIGAGVLPMACPTLFAHLPGPLRILTASGVFMAAF
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHH
CAVTLNLLLSPDQISRTGPCEDATDA
HHHHHHHHCCCHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNHVANRPDPVEARLPPWQLLVCGLQHVLVIYAGIVAVPLIIGSTLGLDGAQQAMLVNAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ILTSGIATLVQTLGLGPFGARLPLIQASSFIALPPMVMIAREYDLPTAYGAVIGGGLATC
HHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHCCCHHHHHHHCCCCHHHHHHHHHHHHHH
LLAPLASRLTRFFPPVVIGSVITVVGLSLMPAAANWLGGGRPGDPGFGAPAHLLLGFATL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
ALTLLITARAGGMGRTLAILLGMAAGCVLGILTGQADFTPMRQVAWMAPPPVLPFGAPAF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCHH
HTVPILVMTMAMMVILVETTGNCLAVSRLAGRTASRAVLARTYAADGLSTLLGGFLGGTP
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YNAFAQNTGLIALTGVRSRFVVAAAGALMVAMGLFPRLGAAVACMPRPVLGGSAILMFGM
CHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHH
TAMAGIQDLARIRPSGTAHALVAAVAIGAGVLPMACPTLFAHLPGPLRILTASGVFMAAF
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHH
CAVTLNLLLSPDQISRTGPCEDATDA
HHHHHHHHCCCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]