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The map label for this gene is ompR [H]

Identifier: 162147183

GI number: 162147183

Start: 1393606

End: 1394397

Strand: Direct

Name: ompR [H]

Synonym: GDI_1388

Alternate gene names: 162147183

Gene position: 1393606-1394397 (Clockwise)

Preceding gene: 162147182

Following gene: 162147184

Centisome position: 35.33

GC content: 68.69

Gene sequence:

>792_bases
ATGATGAATACAACCGTGACGATGTCCCAGACCGCTTCCGACGGCGACCTGCCTGCCCGTATCCTCGTTGTGGAAGATGA
TCCCGGCATGCGCACCCTGCTGGTCAGGGTGCTGCAGGGCGATGGCTACCGCGTGCGCGGCGTGCAGGATGGGCGTGAAA
TGTGGTCGGCGCTGGCGACCTCGCCGGCCGATCTGATCGTGCTGGACGTGATGCTGCCCGGCACCAACGGGCTGGATCTG
TGCCGGTCGCTGCGGCGGGGTGGGGTGCCGGTCGACGGTGTCGTACCCGACCCCCAGATTCCCGTCATCATGGTATCGGC
CCGGGGTGAGGAACTGGACCGGGTCGTCGGCCTGGAACTGGGCGCCGACGATTACGTCGCCAAACCCTTCGGCCAGAAGG
AACTGCTGGCCCGGGTCCGTGCCGTGCTGCGGCGCGGGACGGGCGGCGCGCCCAATGGGCTTGCGGGGGCGCCCCGGCGG
GAAACCCTGAAATTCGCGGGCTGGACGCTGGACCTGCGCCGGCGGGAACTGACCGATCCGTCCGGCACCATCGTCGAGAT
TTCCGGGGCGGAGCACGACCTGCTGGCCAGCTTCCTGGACAATCCGCAGCGGGTGATCGGCCGCGACCGGCTGCTGGAAC
TGTCGCGCACGCGCCTGGGCGACGTGTCGGACCGCAGCGTCGACGTGCTGGTCAGCCGCCTGCGCCGCAAGCTGGGCAAT
GAATCGGAAACCCTGATCCGCACCGTGCGGGGCCTGGGTTACATCTTCACCGCGCCGGTGGACCGAACCTGA

Upstream 100 bases:

>100_bases
CCGGACGGCAGACCCACGACGCGGATCGGCAGGGCCGGGCGGAATACTCCGCCCGGCCCTGCTGTTGTTATGATATTCTT
CCTGTCCCATTCTCTTCAGG

Downstream 100 bases:

>100_bases
ACCCATGGCGGGCCCTGCTTCCCAGAACGCGCCGCCCGGTGTCCGGCGGATCACGCTCTGGCCGCGCGGGCTGGTGGGGC
GGGTCACGGTCGTGCTGCTG

Product: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MMNTTVTMSQTASDGDLPARILVVEDDPGMRTLLVRVLQGDGYRVRGVQDGREMWSALATSPADLIVLDVMLPGTNGLDL
CRSLRRGGVPVDGVVPDPQIPVIMVSARGEELDRVVGLELGADDYVAKPFGQKELLARVRAVLRRGTGGAPNGLAGAPRR
ETLKFAGWTLDLRRRELTDPSGTIVEISGAEHDLLASFLDNPQRVIGRDRLLELSRTRLGDVSDRSVDVLVSRLRRKLGN
ESETLIRTVRGLGYIFTAPVDRT

Sequences:

>Translated_263_residues
MMNTTVTMSQTASDGDLPARILVVEDDPGMRTLLVRVLQGDGYRVRGVQDGREMWSALATSPADLIVLDVMLPGTNGLDL
CRSLRRGGVPVDGVVPDPQIPVIMVSARGEELDRVVGLELGADDYVAKPFGQKELLARVRAVLRRGTGGAPNGLAGAPRR
ETLKFAGWTLDLRRRELTDPSGTIVEISGAEHDLLASFLDNPQRVIGRDRLLELSRTRLGDVSDRSVDVLVSRLRRKLGN
ESETLIRTVRGLGYIFTAPVDRT
>Mature_263_residues
MMNTTVTMSQTASDGDLPARILVVEDDPGMRTLLVRVLQGDGYRVRGVQDGREMWSALATSPADLIVLDVMLPGTNGLDL
CRSLRRGGVPVDGVVPDPQIPVIMVSARGEELDRVVGLELGADDYVAKPFGQKELLARVRAVLRRGTGGAPNGLAGAPRR
ETLKFAGWTLDLRRRELTDPSGTIVEISGAEHDLLASFLDNPQRVIGRDRLLELSRTRLGDVSDRSVDVLVSRLRRKLGN
ESETLIRTVRGLGYIFTAPVDRT

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=242, Percent_Identity=42.9752066115703, Blast_Score=174, Evalue=4e-45,
Organism=Escherichia coli, GI1788394, Length=256, Percent_Identity=35.15625, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790863, Length=246, Percent_Identity=33.739837398374, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786599, Length=240, Percent_Identity=37.9166666666667, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787229, Length=248, Percent_Identity=35.4838709677419, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI2367329, Length=243, Percent_Identity=37.4485596707819, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786784, Length=241, Percent_Identity=36.0995850622407, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790860, Length=244, Percent_Identity=34.4262295081967, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787375, Length=238, Percent_Identity=31.0924369747899, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789402, Length=239, Percent_Identity=35.1464435146443, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786911, Length=239, Percent_Identity=33.4728033472803, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082012, Length=241, Percent_Identity=34.4398340248963, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790552, Length=239, Percent_Identity=30.1255230125523, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=249, Percent_Identity=29.718875502008, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=32.520325203252, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28661; Mature: 28661

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNTTVTMSQTASDGDLPARILVVEDDPGMRTLLVRVLQGDGYRVRGVQDGREMWSALAT
CCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHC
SPADLIVLDVMLPGTNGLDLCRSLRRGGVPVDGVVPDPQIPVIMVSARGEELDRVVGLEL
CCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHCEEE
GADDYVAKPFGQKELLARVRAVLRRGTGGAPNGLAGAPRRETLKFAGWTLDLRRRELTDP
CCCCHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEEECCEEEEEHHHHCCCC
SGTIVEISGAEHDLLASFLDNPQRVIGRDRLLELSRTRLGDVSDRSVDVLVSRLRRKLGN
CCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
ESETLIRTVRGLGYIFTAPVDRT
CHHHHHHHHHHCCEEEECCCCCC
>Mature Secondary Structure
MMNTTVTMSQTASDGDLPARILVVEDDPGMRTLLVRVLQGDGYRVRGVQDGREMWSALAT
CCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHC
SPADLIVLDVMLPGTNGLDLCRSLRRGGVPVDGVVPDPQIPVIMVSARGEELDRVVGLEL
CCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHCEEE
GADDYVAKPFGQKELLARVRAVLRRGTGGAPNGLAGAPRRETLKFAGWTLDLRRRELTDP
CCCCHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEEECCEEEEEHHHHCCCC
SGTIVEISGAEHDLLASFLDNPQRVIGRDRLLELSRTRLGDVSDRSVDVLVSRLRRKLGN
CCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
ESETLIRTVRGLGYIFTAPVDRT
CHHHHHHHHHHCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]