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The map label for this gene is yafC [H]

Identifier: 162147169

GI number: 162147169

Start: 1377483

End: 1378448

Strand: Direct

Name: yafC [H]

Synonym: GDI_1374

Alternate gene names: 162147169

Gene position: 1377483-1378448 (Clockwise)

Preceding gene: 162147167

Following gene: 162147174

Centisome position: 34.92

GC content: 72.77

Gene sequence:

>966_bases
TTGCGCGGTCCGGCACGCGGCGCAGAGACAGGAGGGGATGTGGACTACGTGACCTGCCTGCGCGTGCTGGTCGCCACCGC
CGACGGCGGCAGCCTGTCGCGGGCGGCGGGGGTGCTGCATATGACCGTCTCCTCGGTGTCGCGGGCGATCACCGTGCTGG
AACAGGACCTGGGCGCCGCCGTCTTCAACCGTTCGACCCGGGGATTGCACCTGACGGAAATCGGCGGCCGGTTCCTGGCC
CGGGCGCGCGACATCCTGGCCGAACTGGATGATGCCCGGGCCGAGGCCGCGTCGCTGAACGCCGCCCCCCGGGGCCGCCT
GCGGGTGCTGGCCTCGCCATCGGTCGGCCGGGCGGTGATCGCGCCGCTGCTGCCGGGGTTCCTGAAGGCCTATCCCGATA
TCGACCTCGACCTGCGCAGCGGGCCGGCCGGCGGGGACCTGTCGCACATCCTGATCGAAAGCGGGGCGGATATCGCGGTC
GTCACCGGGCGGCCGCCGGATTCCGGCCTGCTGTTCCGGCCGGTGCTGACGGGATCATGGTGGCTGATGGCGCCGCCGGG
GCGGGTGCCTGCCGATGCCGGGCCCGATGACCTGTCCGGCTTGCCCTGCCTGGCCCCGTCGGGCCAGGAGGCGGAATGGC
GCTGCCATCGTGGCGGCCGGACGGTCGTCCTGCCCACGACAGGGCGGATTACGGCGGATTCGCCGGACATGCTGCGCGCC
CTGGCGGCCGCCGGGGCCGGGCTGGCGCTGCTGCCGGACTGGATGTTCCTGCATGCCGCGCCGGGCGAGGCAGGGTTGGA
GCGGGTTCTGGCCGACTGGCGCATCACGCCGGCCGCGGATGAATCCTGCGACCTGTCGGCGCTCTATCCCCGCAAGAAGG
TGGTGCCGCCCAAGACCCGGGCCTTCGTGACCGCGCTGGGCGCCGCCGGCCGGGCCTTCGATGCGCGGATGATCTGTCTT
AAATGA

Upstream 100 bases:

>100_bases
CCTCTTCTCTTTGCCATCCGGTTCTGTGATTTGCCGGACTGGACGCGGACTGTAGGGTACGGGCTCCGCCAGGCGGAACG
GCCGGTTCGGGAAAAGAGTT

Downstream 100 bases:

>100_bases
TATTCCGCAGGACGATCCGGACGTGTTTTTCACCATGTGCCGTGCTGATGGCGAAGTCCAGCGTGCTTCCGGTCGGCCCT
GTCAGAAGCGACCAGATATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MRGPARGAETGGDVDYVTCLRVLVATADGGSLSRAAGVLHMTVSSVSRAITVLEQDLGAAVFNRSTRGLHLTEIGGRFLA
RARDILAELDDARAEAASLNAAPRGRLRVLASPSVGRAVIAPLLPGFLKAYPDIDLDLRSGPAGGDLSHILIESGADIAV
VTGRPPDSGLLFRPVLTGSWWLMAPPGRVPADAGPDDLSGLPCLAPSGQEAEWRCHRGGRTVVLPTTGRITADSPDMLRA
LAAAGAGLALLPDWMFLHAAPGEAGLERVLADWRITPAADESCDLSALYPRKKVVPPKTRAFVTALGAAGRAFDARMICL
K

Sequences:

>Translated_321_residues
MRGPARGAETGGDVDYVTCLRVLVATADGGSLSRAAGVLHMTVSSVSRAITVLEQDLGAAVFNRSTRGLHLTEIGGRFLA
RARDILAELDDARAEAASLNAAPRGRLRVLASPSVGRAVIAPLLPGFLKAYPDIDLDLRSGPAGGDLSHILIESGADIAV
VTGRPPDSGLLFRPVLTGSWWLMAPPGRVPADAGPDDLSGLPCLAPSGQEAEWRCHRGGRTVVLPTTGRITADSPDMLRA
LAAAGAGLALLPDWMFLHAAPGEAGLERVLADWRITPAADESCDLSALYPRKKVVPPKTRAFVTALGAAGRAFDARMICL
K
>Mature_321_residues
MRGPARGAETGGDVDYVTCLRVLVATADGGSLSRAAGVLHMTVSSVSRAITVLEQDLGAAVFNRSTRGLHLTEIGGRFLA
RARDILAELDDARAEAASLNAAPRGRLRVLASPSVGRAVIAPLLPGFLKAYPDIDLDLRSGPAGGDLSHILIESGADIAV
VTGRPPDSGLLFRPVLTGSWWLMAPPGRVPADAGPDDLSGLPCLAPSGQEAEWRCHRGGRTVVLPTTGRITADSPDMLRA
LAAAGAGLALLPDWMFLHAAPGEAGLERVLADWRITPAADESCDLSALYPRKKVVPPKTRAFVTALGAAGRAFDARMICL
K

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=32.5423728813559, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789639, Length=296, Percent_Identity=30.0675675675676, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI145693193, Length=317, Percent_Identity=25.8675078864353, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789440, Length=241, Percent_Identity=25.3112033195021, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787128, Length=288, Percent_Identity=26.7361111111111, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787589, Length=264, Percent_Identity=28.030303030303, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081978, Length=241, Percent_Identity=27.8008298755187, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790262, Length=245, Percent_Identity=28.1632653061224, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787806, Length=255, Percent_Identity=27.843137254902, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693105, Length=161, Percent_Identity=23.6024844720497, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787879, Length=123, Percent_Identity=38.2113821138211, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788297, Length=241, Percent_Identity=26.1410788381743, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI157672245, Length=121, Percent_Identity=33.0578512396694, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789173, Length=245, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790208, Length=297, Percent_Identity=24.5791245791246, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33498; Mature: 33498

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGPARGAETGGDVDYVTCLRVLVATADGGSLSRAAGVLHMTVSSVSRAITVLEQDLGAA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFNRSTRGLHLTEIGGRFLARARDILAELDDARAEAASLNAAPRGRLRVLASPSVGRAVI
HHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHH
APLLPGFLKAYPDIDLDLRSGPAGGDLSHILIESGADIAVVTGRPPDSGLLFRPVLTGSW
HHHHHHHHHHCCCCCEEECCCCCCCCCEEEEEECCCCEEEEECCCCCCCEEEEEECCCCE
WLMAPPGRVPADAGPDDLSGLPCLAPSGQEAEWRCHRGGRTVVLPTTGRITADSPDMLRA
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCEECCCHHHHHH
LAAAGAGLALLPDWMFLHAAPGEAGLERVLADWRITPAADESCDLSALYPRKKVVPPKTR
HHHCCCCCEECCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCHH
AFVTALGAAGRAFDARMICLK
HHHHHHCCCCCCCCCEEEEEC
>Mature Secondary Structure
MRGPARGAETGGDVDYVTCLRVLVATADGGSLSRAAGVLHMTVSSVSRAITVLEQDLGAA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFNRSTRGLHLTEIGGRFLARARDILAELDDARAEAASLNAAPRGRLRVLASPSVGRAVI
HHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHH
APLLPGFLKAYPDIDLDLRSGPAGGDLSHILIESGADIAVVTGRPPDSGLLFRPVLTGSW
HHHHHHHHHHCCCCCEEECCCCCCCCCEEEEEECCCCEEEEECCCCCCCEEEEEECCCCE
WLMAPPGRVPADAGPDDLSGLPCLAPSGQEAEWRCHRGGRTVVLPTTGRITADSPDMLRA
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCEECCCHHHHHH
LAAAGAGLALLPDWMFLHAAPGEAGLERVLADWRITPAADESCDLSALYPRKKVVPPKTR
HHHCCCCCEECCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCHH
AFVTALGAAGRAFDARMICLK
HHHHHHCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]