Click here to switch to the map view.

The map label for this gene is hrcA [H]

Identifier: 162147174

GI number: 162147174

Start: 1382831

End: 1383898

Strand: Direct

Name: hrcA [H]

Synonym: GDI_1379

Alternate gene names: 162147174

Gene position: 1382831-1383898 (Clockwise)

Preceding gene: 162147169

Following gene: 162147175

Centisome position: 35.06

GC content: 68.63

Gene sequence:

>1068_bases
ATGGACCCCGCCACGCTGTCCCCCCGTCCTGCCCTGCCGCCCGGGCTGGACGCAAGATCCGCGGCGATCCTGCGTGAAAT
CGTCGAACAGTACGTGGAAACCGGCGAACCGGTCGGCTCGCGCACGCTCTCGCGCCGCCTGCCGCTGTCGCTGTCCCCGG
CCACGATCCGCAACGTCATGGCGGACCTGACCGAGGCCGGACTGCTGTTTTCGCCCCACGCCTCGGCCGGCCGCCTGCCC
ACCGAAAAGGGCGTGCGGCTGTTCGTCGACGGCCTGCTGCAGTTCGGCAGCCTGACCGAGGACGAGCGCGAGACGATCAC
CCGCTCGCTGGAAATGCGCGGCCGGTCGCTGCAGGACATGCTGTCCGAGGCCTCGTCTATGCTCTCGGGCCTGTCCTCGG
CGGCGGGTCTGGTCCTGGCGCCCAAGAGCGACGGTGCGGTGAAGCATATCGAATTCGTGGCCCTAGGGCCGCGCCGCGCG
CTGGTCATCCTGGTGGGGGCGGACGGGCAGGTGGAAAACCGGGTGATCGAAACCCCGATCGGCCTGCCGCCCTCGGCTCT
GGTCGAGGCGGGGAACTACCTGAATGCCCACCTGACCGGTCGCACGCTGGAGGGCCTGCGCGAGCATGTCAGCGCCAACA
TGGCCGCCAATCGCAATGAACTGCATCATCTGACGGCCGAAGTGGTGGCCAGCGGCCTGGCGACGTGGAGCGAGCTGGAT
CGCGGCGGCACGCTGTTCGTGCGCGGCCAGGCGCGGCTGCTGGCCGACGTGACGGAGATCGAGCGCCTGTCCACCATCCA
GATGCTGTTCGAACGGCTAGAAACGCAGGAAACGATGCTGCGCCTGCTGGACCTGGCGCAGGAATCCGAGGGGGTGCGGA
TCTTCATCGGGGCCGAAAGCGGCGTGTTCGGCCTGTCGGGCATGTCGGCGGTGGTGGCCCCGGCGCGGACCGACAGCAAC
CGCATCGTGGGTGCGATCGGCGTGATCGGGCCGACGCGCATCAATTATGGCCGCATTATCCCGGTGGTGGATTACACCGC
GCGGGTTATCGGCCGGATGCTGGGGTGA

Upstream 100 bases:

>100_bases
TCCCGTGCTTGTCATGGCCCGCTTCCGGTTCCAGATTTAGGCTGGTCGTTTTTTCGGGCTGGCGTTTCCTGGCCGGTCGA
ACAGGGAGGAACCAAGGCCG

Downstream 100 bases:

>100_bases
CTGCCTCGCCAGTGCCATATTGTTTCGTTCTTTTTTGAAGAAAGAAGAAATCTTCTTCATGCAGGAGGCCCGAATGTCCC
ACCCAGACGCCCGCCAGGCG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MDPATLSPRPALPPGLDARSAAILREIVEQYVETGEPVGSRTLSRRLPLSLSPATIRNVMADLTEAGLLFSPHASAGRLP
TEKGVRLFVDGLLQFGSLTEDERETITRSLEMRGRSLQDMLSEASSMLSGLSSAAGLVLAPKSDGAVKHIEFVALGPRRA
LVILVGADGQVENRVIETPIGLPPSALVEAGNYLNAHLTGRTLEGLREHVSANMAANRNELHHLTAEVVASGLATWSELD
RGGTLFVRGQARLLADVTEIERLSTIQMLFERLETQETMLRLLDLAQESEGVRIFIGAESGVFGLSGMSAVVAPARTDSN
RIVGAIGVIGPTRINYGRIIPVVDYTARVIGRMLG

Sequences:

>Translated_355_residues
MDPATLSPRPALPPGLDARSAAILREIVEQYVETGEPVGSRTLSRRLPLSLSPATIRNVMADLTEAGLLFSPHASAGRLP
TEKGVRLFVDGLLQFGSLTEDERETITRSLEMRGRSLQDMLSEASSMLSGLSSAAGLVLAPKSDGAVKHIEFVALGPRRA
LVILVGADGQVENRVIETPIGLPPSALVEAGNYLNAHLTGRTLEGLREHVSANMAANRNELHHLTAEVVASGLATWSELD
RGGTLFVRGQARLLADVTEIERLSTIQMLFERLETQETMLRLLDLAQESEGVRIFIGAESGVFGLSGMSAVVAPARTDSN
RIVGAIGVIGPTRINYGRIIPVVDYTARVIGRMLG
>Mature_355_residues
MDPATLSPRPALPPGLDARSAAILREIVEQYVETGEPVGSRTLSRRLPLSLSPATIRNVMADLTEAGLLFSPHASAGRLP
TEKGVRLFVDGLLQFGSLTEDERETITRSLEMRGRSLQDMLSEASSMLSGLSSAAGLVLAPKSDGAVKHIEFVALGPRRA
LVILVGADGQVENRVIETPIGLPPSALVEAGNYLNAHLTGRTLEGLREHVSANMAANRNELHHLTAEVVASGLATWSELD
RGGTLFVRGQARLLADVTEIERLSTIQMLFERLETQETMLRLLDLAQESEGVRIFIGAESGVFGLSGMSAVVAPARTDSN
RIVGAIGVIGPTRINYGRIIPVVDYTARVIGRMLG

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 37982; Mature: 37982

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPATLSPRPALPPGLDARSAAILREIVEQYVETGEPVGSRTLSRRLPLSLSPATIRNVM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHH
ADLTEAGLLFSPHASAGRLPTEKGVRLFVDGLLQFGSLTEDERETITRSLEMRGRSLQDM
HHHHHCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHH
LSEASSMLSGLSSAAGLVLAPKSDGAVKHIEFVALGPRRALVILVGADGQVENRVIETPI
HHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEEECCCCEEEEEECCCCCCCCEEEECCC
GLPPSALVEAGNYLNAHLTGRTLEGLREHVSANMAANRNELHHLTAEVVASGLATWSELD
CCCHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
RGGTLFVRGQARLLADVTEIERLSTIQMLFERLETQETMLRLLDLAQESEGVRIFIGAES
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GVFGLSGMSAVVAPARTDSNRIVGAIGVIGPTRINYGRIIPVVDYTARVIGRMLG
CCCCCCCCHHHEECCCCCCCCEEEEEECCCCCEECCCCEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MDPATLSPRPALPPGLDARSAAILREIVEQYVETGEPVGSRTLSRRLPLSLSPATIRNVM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHH
ADLTEAGLLFSPHASAGRLPTEKGVRLFVDGLLQFGSLTEDERETITRSLEMRGRSLQDM
HHHHHCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHH
LSEASSMLSGLSSAAGLVLAPKSDGAVKHIEFVALGPRRALVILVGADGQVENRVIETPI
HHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEEECCCCEEEEEECCCCCCCCEEEECCC
GLPPSALVEAGNYLNAHLTGRTLEGLREHVSANMAANRNELHHLTAEVVASGLATWSELD
CCCHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
RGGTLFVRGQARLLADVTEIERLSTIQMLFERLETQETMLRLLDLAQESEGVRIFIGAES
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GVFGLSGMSAVVAPARTDSNRIVGAIGVIGPTRINYGRIIPVVDYTARVIGRMLG
CCCCCCCCHHHEECCCCCCCCEEEEEECCCCCEECCCCEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA