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The map label for this gene is ccmB [H]

Identifier: 162147148

GI number: 162147148

Start: 1353204

End: 1353884

Strand: Reverse

Name: ccmB [H]

Synonym: GDI_1353

Alternate gene names: 162147148

Gene position: 1353884-1353204 (Counterclockwise)

Preceding gene: 162147149

Following gene: 162147146

Centisome position: 34.33

GC content: 74.45

Gene sequence:

>681_bases
ATGAACGCGTCGATTCCCGCCCTGCTGGCCGCCGTCATCGGGCGCGACCTGCGGCTGGCGCTGCGTCACGGGGCCGACAC
GCTGGGTGCCGTGCTGTTCTTCATCCTGGCGGGGGCGCTGTTTCCCCTGGCGCTGGGCCCGTCGCCCGAACTGCTGCGCC
GGATGGCGCCGGGCATCGTCTGGGTCTGCGCCCTGCTGGCCGCCCTGCTGCCGCTGGACCGCCTGTTCGGGTCCGAACTG
GAAGACGGGTCGCTGGACCAGTTGATGCTGTCGGGCCTGCCGCCCGCCCTGGTCGCGCTGGCCAAGATGGTGGCGCACTG
GCTGACCACCGGCCTGCCGCTTCTGGTCGCGGCGGGGCCGCTGGCCATCATGCTGGGACTGCCGCTGCCGGTCCTGCCGA
TCCTGCTGGGGGGGCTGGCGCTGGGCACGATCGTGCTGTCGCTGATCGGCGGCATGGCGGCATCCGTGGTGCTGGGCGCG
CGGCGCGGCGGCGTGCTGCTGCCGCTGCTGGTGCTGCCGCTGGCAACCCCCGCGCTGATCTTCGGCGCGGCGGCGCTGGA
CGCGGCGCAGACCGGCCTGTCCTGGACGCCGGACCTGGAATTGCTGGGCGCCTTCCTGGCCGGGGCACTGCCGCTGTGCC
CGCTGGCAGCGGGGGCCGGGTTGCGCGCGGCGGTCGAGTAG

Upstream 100 bases:

>100_bases
AAACCCTGGTCCTGCCCGGCGCGACCGAACCGGCGCCGGATTTTGGGATGGAATCAGGATTCGATTCCCATGCGGACCAC
TCCCACGCGGACCACTGGGC

Downstream 100 bases:

>100_bases
GGGGCAGTCCGGAGCCAAAGGCCGCCGGCCTTTGGAAACCGATTCGTTATGATCCGATCGGTGTGCGGGGCATCACGCCC
CTGCACGGTCCATCAGATAT

Product: Heme exporter protein B

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MNASIPALLAAVIGRDLRLALRHGADTLGAVLFFILAGALFPLALGPSPELLRRMAPGIVWVCALLAALLPLDRLFGSEL
EDGSLDQLMLSGLPPALVALAKMVAHWLTTGLPLLVAAGPLAIMLGLPLPVLPILLGGLALGTIVLSLIGGMAASVVLGA
RRGGVLLPLLVLPLATPALIFGAAALDAAQTGLSWTPDLELLGAFLAGALPLCPLAAGAGLRAAVE

Sequences:

>Translated_226_residues
MNASIPALLAAVIGRDLRLALRHGADTLGAVLFFILAGALFPLALGPSPELLRRMAPGIVWVCALLAALLPLDRLFGSEL
EDGSLDQLMLSGLPPALVALAKMVAHWLTTGLPLLVAAGPLAIMLGLPLPVLPILLGGLALGTIVLSLIGGMAASVVLGA
RRGGVLLPLLVLPLATPALIFGAAALDAAQTGLSWTPDLELLGAFLAGALPLCPLAAGAGLRAAVE
>Mature_226_residues
MNASIPALLAAVIGRDLRLALRHGADTLGAVLFFILAGALFPLALGPSPELLRRMAPGIVWVCALLAALLPLDRLFGSEL
EDGSLDQLMLSGLPPALVALAKMVAHWLTTGLPLLVAAGPLAIMLGLPLPVLPILLGGLALGTIVLSLIGGMAASVVLGA
RRGGVLLPLLVLPLATPALIFGAAALDAAQTGLSWTPDLELLGAFLAGALPLCPLAAGAGLRAAVE

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=211, Percent_Identity=47.8672985781991, Blast_Score=147, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22742; Mature: 22742

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASIPALLAAVIGRDLRLALRHGADTLGAVLFFILAGALFPLALGPSPELLRRMAPGIV
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHH
WVCALLAALLPLDRLFGSELEDGSLDQLMLSGLPPALVALAKMVAHWLTTGLPLLVAAGP
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHH
LAIMLGLPLPVLPILLGGLALGTIVLSLIGGMAASVVLGARRGGVLLPLLVLPLATPALI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FGAAALDAAQTGLSWTPDLELLGAFLAGALPLCPLAAGAGLRAAVE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCC
>Mature Secondary Structure
MNASIPALLAAVIGRDLRLALRHGADTLGAVLFFILAGALFPLALGPSPELLRRMAPGIV
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHH
WVCALLAALLPLDRLFGSELEDGSLDQLMLSGLPPALVALAKMVAHWLTTGLPLLVAAGP
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHH
LAIMLGLPLPVLPILLGGLALGTIVLSLIGGMAASVVLGARRGGVLLPLLVLPLATPALI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FGAAALDAAQTGLSWTPDLELLGAFLAGALPLCPLAAGAGLRAAVE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]