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The map label for this gene is ltaE [H]

Identifier: 162147099

GI number: 162147099

Start: 1304070

End: 1305122

Strand: Reverse

Name: ltaE [H]

Synonym: GDI_1304

Alternate gene names: 162147099

Gene position: 1305122-1304070 (Counterclockwise)

Preceding gene: 162147103

Following gene: 162147096

Centisome position: 33.09

GC content: 70.09

Gene sequence:

>1053_bases
GTGGTAGAGCAGATACGCAAAAATTTCAGCAGCGACAACGTCGTTCCGGCCTGCCCTGCCGTGATGTCCGCCCTGATGGC
GGCCAACGAGGGCGCCGCCCCCGCCTACGGCGCCGACGCCTGGACCGCGCGCCTGCAGCAGGTGGCGGCGGATGTCTTCC
AGCACGCGGTCCAGGTCTTTCCCGTCACCACCGGCACGGCGGCGAACGCGCTGGCGCTGGCGGCGATAACCCCACCCTAT
GGCGCGGTCCTGTGCGACGAGAGCGCGCATATCGTCCAGTCCGAATGCGGGGCGCCCGATTTCTATACCGGCGGCGCGCG
GCTGCTGACGATCCCGTCCGAAGACGGGCGCATGGACCCCGCTGCCCTGTCCTATGTGCTGGACCGCCACCCGGCTTCCA
ACGTGCAGGACAACCTGCCGACGACGCTGAGCCTGACGCAGGCCACGGAATGGGGCACCGTCTACGACCCGGCGCGGATC
GCGGACCTGACGGCGCGGGCGCGCGCCCGGGGCCTGGCGGTGCATCTGGACGGCGCACGGCTGGCCAACGCCATCGTCCA
TCTGGGATGCACGCCCGCCGAGGCGACATGGAAGGCCGGGATCGACGTGCTGGCGCTGGGCGCGACCAAGAACGGCGCGA
TGGCGGCCGAAGCCGTGATCATCTTCGACCCCGCGCGGGCCGAGCAGTTCGCCCGGCGCCGCAAGCGCGGCGGCCATGGC
TGGTCCAAGCAGCGCTTCCTCAGCGCACAGTTGCTGGCCTGCCTGGAAGACGATCTGTGGCTGAACAACGCGCGGCAGGC
CAACGCCATGGCGCACCGGCTGGCAGGCGGCCTGTTCCGCCACCCCGGCGCCCGCCTGGTCTATGAAACCCAGGCCAACG
AGATCTTCGTCATGCTGCCCGACCGGGCGATCGCGCACCTGCGCGCGGCAGGGTTCGTCTTCCGCGACTGGCCCACCCCG
CTGGGCGTGGAGGGGACCGTCGTGCGGCTGGTCACCAGTTATTATACGCGCGTGGCGGATGTTGACGCGTTCCTGGCGAC
CTGGCGGAAGTAA

Upstream 100 bases:

>100_bases
ACCGGCGCGGGTTCGGCAGGCACGGGATCGGTCGTTCGATCGGTCATGGGGCGCTCCGGACAGCGGGCATGGGCCAGATG
GCATAGGACAGGGGGCCAGG

Downstream 100 bases:

>100_bases
AAGTACGACATGGCGGGCCGCCCGGCAGGGCGGCCGCCCGCCCGTCAGTCGTTGCCGTCGGGGTCGCTGTTGCCGTTGCC
GCTGTCGCCCTCATCCGAGC

Product: threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MVEQIRKNFSSDNVVPACPAVMSALMAANEGAAPAYGADAWTARLQQVAADVFQHAVQVFPVTTGTAANALALAAITPPY
GAVLCDESAHIVQSECGAPDFYTGGARLLTIPSEDGRMDPAALSYVLDRHPASNVQDNLPTTLSLTQATEWGTVYDPARI
ADLTARARARGLAVHLDGARLANAIVHLGCTPAEATWKAGIDVLALGATKNGAMAAEAVIIFDPARAEQFARRRKRGGHG
WSKQRFLSAQLLACLEDDLWLNNARQANAMAHRLAGGLFRHPGARLVYETQANEIFVMLPDRAIAHLRAAGFVFRDWPTP
LGVEGTVVRLVTSYYTRVADVDAFLATWRK

Sequences:

>Translated_350_residues
MVEQIRKNFSSDNVVPACPAVMSALMAANEGAAPAYGADAWTARLQQVAADVFQHAVQVFPVTTGTAANALALAAITPPY
GAVLCDESAHIVQSECGAPDFYTGGARLLTIPSEDGRMDPAALSYVLDRHPASNVQDNLPTTLSLTQATEWGTVYDPARI
ADLTARARARGLAVHLDGARLANAIVHLGCTPAEATWKAGIDVLALGATKNGAMAAEAVIIFDPARAEQFARRRKRGGHG
WSKQRFLSAQLLACLEDDLWLNNARQANAMAHRLAGGLFRHPGARLVYETQANEIFVMLPDRAIAHLRAAGFVFRDWPTP
LGVEGTVVRLVTSYYTRVADVDAFLATWRK
>Mature_350_residues
MVEQIRKNFSSDNVVPACPAVMSALMAANEGAAPAYGADAWTARLQQVAADVFQHAVQVFPVTTGTAANALALAAITPPY
GAVLCDESAHIVQSECGAPDFYTGGARLLTIPSEDGRMDPAALSYVLDRHPASNVQDNLPTTLSLTQATEWGTVYDPARI
ADLTARARARGLAVHLDGARLANAIVHLGCTPAEATWKAGIDVLALGATKNGAMAAEAVIIFDPARAEQFARRRKRGGHG
WSKQRFLSAQLLACLEDDLWLNNARQANAMAHRLAGGLFRHPGARLVYETQANEIFVMLPDRAIAHLRAAGFVFRDWPTP
LGVEGTVVRLVTSYYTRVADVDAFLATWRK

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=271, Percent_Identity=24.7232472324723, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 37569; Mature: 37569

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEQIRKNFSSDNVVPACPAVMSALMAANEGAAPAYGADAWTARLQQVAADVFQHAVQVF
CHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEE
PVTTGTAANALALAAITPPYGAVLCDESAHIVQSECGAPDFYTGGARLLTIPSEDGRMDP
ECCCCCCCCCEEEEEECCCCCEEEECCCHHHHHHHCCCCCEECCCEEEEEECCCCCCCCH
AALSYVLDRHPASNVQDNLPTTLSLTQATEWGTVYDPARIADLTARARARGLAVHLDGAR
HHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCHH
LANAIVHLGCTPAEATWKAGIDVLALGATKNGAMAAEAVIIFDPARAEQFARRRKRGGHG
HHHHHHHCCCCCCCCHHHCCCEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCC
WSKQRFLSAQLLACLEDDLWLNNARQANAMAHRLAGGLFRHPGARLVYETQANEIFVMLP
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEC
DRAIAHLRAAGFVFRDWPTPLGVEGTVVRLVTSYYTRVADVDAFLATWRK
CHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVEQIRKNFSSDNVVPACPAVMSALMAANEGAAPAYGADAWTARLQQVAADVFQHAVQVF
CHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEE
PVTTGTAANALALAAITPPYGAVLCDESAHIVQSECGAPDFYTGGARLLTIPSEDGRMDP
ECCCCCCCCCEEEEEECCCCCEEEECCCHHHHHHHCCCCCEECCCEEEEEECCCCCCCCH
AALSYVLDRHPASNVQDNLPTTLSLTQATEWGTVYDPARIADLTARARARGLAVHLDGAR
HHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCHH
LANAIVHLGCTPAEATWKAGIDVLALGATKNGAMAAEAVIIFDPARAEQFARRRKRGGHG
HHHHHHHCCCCCCCCHHHCCCEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCC
WSKQRFLSAQLLACLEDDLWLNNARQANAMAHRLAGGLFRHPGARLVYETQANEIFVMLP
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEC
DRAIAHLRAAGFVFRDWPTPLGVEGTVVRLVTSYYTRVADVDAFLATWRK
CHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]