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The map label for this gene is luxR [H]

Identifier: 162147030

GI number: 162147030

Start: 1228407

End: 1229069

Strand: Reverse

Name: luxR [H]

Synonym: GDI_1235

Alternate gene names: 162147030

Gene position: 1229069-1228407 (Counterclockwise)

Preceding gene: 162147031

Following gene: 162147028

Centisome position: 31.16

GC content: 68.93

Gene sequence:

>663_bases
ATGAGCGGGCAGGCACCGGAAGACCGGCCCCGGCCGCATGTCGTCGTCGTCGATGACGATGCCGGGGTGCGCGCGTCGCT
GGACAGCCTGTTCCGTTCCGCCGGCTTCACCGTGACCCTGTTTGCCGACCCGCACGCCTTCCTGAAGGCCGGCGTGCCAC
AGGGGCCGTGCTGCCTGGTACTGGACGTGAAGCTGGGCCGGATCGACGGCCTCGACTTCCACGAGGCGATCGTCGACGCG
GGACTCCGCATCCCGACCATCATCATGACCGGTCATGGGGACATTCCGATGGCCGTCCGGGGCATGCGGACGGGGGCGAT
CGATTTCCTGGCCAAGCCGTTCGGCGACCAGGCGATGCTGTCGGCTGTCTCGGACGCGGTGGAGACATGGTGGCGGCAAT
GGCGCCAGGACCAGGGCGCGGCCGACGCCCGGCAGCGTTACGCCACCCTGTCGGCGCGCGAGCGCGAAGTCATGGCCCTG
GTCGTCGCGGGCCTGATGAACAAGCAGATCGCGGCCCGTCTTTCCCTGAGCGTCGTCGCGATCAAGGCCCATCGCTCCGG
CGTCATGAGGAAGATGGGCGCCGATTCCCTGGCCGACCTGGTCCGCCTGGGGGAAAGGCTGGGCGTCCGGGACGAGGAGG
TCAGCCGGTACGGAAAGGTCTGA

Upstream 100 bases:

>100_bases
GGTCGCATGGCGGTGCGATCACGGCCGCAAACGGCACGCCCTCCGGCGCCGTCATAACGGTCAGGCTGCCCGCCGCGCAC
GCCACGGCGGCGGCAGCGGC

Downstream 100 bases:

>100_bases
CGATGCAGACCATCAGGACCGCATGACCACCCGTTCGCTGACATCCGGAACCGTGAAGCCGAACACCTGTCCATAGAAAT
CCAGTTCCAGGTCCAGCGCG

Product: transcriptional regulatory protein

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSGQAPEDRPRPHVVVVDDDAGVRASLDSLFRSAGFTVTLFADPHAFLKAGVPQGPCCLVLDVKLGRIDGLDFHEAIVDA
GLRIPTIIMTGHGDIPMAVRGMRTGAIDFLAKPFGDQAMLSAVSDAVETWWRQWRQDQGAADARQRYATLSAREREVMAL
VVAGLMNKQIAARLSLSVVAIKAHRSGVMRKMGADSLADLVRLGERLGVRDEEVSRYGKV

Sequences:

>Translated_220_residues
MSGQAPEDRPRPHVVVVDDDAGVRASLDSLFRSAGFTVTLFADPHAFLKAGVPQGPCCLVLDVKLGRIDGLDFHEAIVDA
GLRIPTIIMTGHGDIPMAVRGMRTGAIDFLAKPFGDQAMLSAVSDAVETWWRQWRQDQGAADARQRYATLSAREREVMAL
VVAGLMNKQIAARLSLSVVAIKAHRSGVMRKMGADSLADLVRLGERLGVRDEEVSRYGKV
>Mature_219_residues
SGQAPEDRPRPHVVVVDDDAGVRASLDSLFRSAGFTVTLFADPHAFLKAGVPQGPCCLVLDVKLGRIDGLDFHEAIVDAG
LRIPTIIMTGHGDIPMAVRGMRTGAIDFLAKPFGDQAMLSAVSDAVETWWRQWRQDQGAADARQRYATLSAREREVMALV
VAGLMNKQIAARLSLSVVAIKAHRSGVMRKMGADSLADLVRLGERLGVRDEEVSRYGKV

Specific function: Member of the two-component regulatory system nodV/nodW probably involved in the regulation of the transcription of genes involved in the nodulation process [H]

COG id: COG4566

COG function: function code T; Response regulator

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=34.1666666666667, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23862; Mature: 23731

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQAPEDRPRPHVVVVDDDAGVRASLDSLFRSAGFTVTLFADPHAFLKAGVPQGPCCLV
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCHHHHHCCCCCCCEEEE
LDVKLGRIDGLDFHEAIVDAGLRIPTIIMTGHGDIPMAVRGMRTGAIDFLAKPFGDQAML
EEEEECCCCCCCHHHHHHHCCCCCCEEEEECCCCCCHHHHCCCCCHHHHHHCCCCCHHHH
SAVSDAVETWWRQWRQDQGAADARQRYATLSAREREVMALVVAGLMNKQIAARLSLSVVA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
IKAHRSGVMRKMGADSLADLVRLGERLGVRDEEVSRYGKV
EEHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure 
SGQAPEDRPRPHVVVVDDDAGVRASLDSLFRSAGFTVTLFADPHAFLKAGVPQGPCCLV
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCHHHHHCCCCCCCEEEE
LDVKLGRIDGLDFHEAIVDAGLRIPTIIMTGHGDIPMAVRGMRTGAIDFLAKPFGDQAML
EEEEECCCCCCCHHHHHHHCCCCCCEEEEECCCCCCHHHHCCCCCHHHHHHCCCCCHHHH
SAVSDAVETWWRQWRQDQGAADARQRYATLSAREREVMALVVAGLMNKQIAARLSLSVVA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
IKAHRSGVMRKMGADSLADLVRLGERLGVRDEEVSRYGKV
EEHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2320582; 11157954; 12597275 [H]